Human T-cell leukemia virus type I Tax associates with and is negatively regulated by the NF-kappa B2 p100 gene product: implications for viral latency

No abstract is available for this paper.

• Publication year

  1994

• Venue

  Molecular and Cellular Biology

• Publication date

  1994-02-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/mcb.14.2.1374-1382.1994PMID 8289813PMCID PMC358492
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Autoregulation of the NF-kappa B transactivator RelA (p65) by multiple cytoplasmic inhibitors containing ankyrin motifs.

  1994cited by this paper
• The trans-activator tax of human T-cell leukemia virus type 1 (HTLV-1) interacts with cAMP-responsive element (CRE) binding and CRE modulator proteins that bind to the 21-base-pair enhancer of HTLV-1.

  1993cited by this paper
• NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway.

  1993cited by this paper
• p105 and p98 precursor proteins play an active role in NF-kappa B-mediated signal transduction.

  1993cited by this paper
• The NF‐kappa B precursor p105 and the proto‐oncogene product Bcl‐3 are I kappa B molecules and control nuclear translocation of NF‐kappa B.

  1993cited by this paper
• The transcriptionally active factors mediating the effect of the HTLV-I Tax transactivator on the IL-2R alpha kappa B enhancer include the product of the c-rel proto-oncogene.

  1993cited by this paper
• Candidate proto-oncogene bcl-3 encodes a subunit-specific inhibitor of transcription factor NF-κB

  1992cited by this paper
• I kappa B/MAD-3 masks the nuclear localization signal of NF-kappa B p65 and requires the transactivation domain to inhibit NF-kappa B p65 DNA binding.

  1992cited by this paper
• Mutations of the p53 gene in adult T-cell leukemia.

  1992cited by this paper
• cactus, a gene involved in dorsoventral pattern formation of Drosophila, is related to the I kappa B gene family of vertebrates.

  1992cited by this paper
• Expression of alternatively spliced human T-lymphotropic virus type I pX mRNA in infected cell lines and in primary uncultured cells from patients with adult T-cell leukemia/lymphoma and healthy carriers.

  1992cited by this paper
• Characterization of a novel nuclear localization signal in the HTLV-I tax transactivator protein.

  1992cited by this paper
• cactus, a gene involved in dorsoventral pattern formation of Drosophila, is related to the IκB gene family of vertebrates

  1992cited by this paper
• The 65-kDa subunit of human NF-kappa B functions as a potent transcriptional activator and a target for v-Rel-mediated repression.

  1992cited by this paper
• The ankyrin repeat domains of the NF-kappa B precursor p105 and the protooncogene bcl-3 act as specific inhibitors of NF-kappa B DNA binding.

  1992cited by this paper
• Characterization of the Drosophila cactus locus and analysis of interactions between cactus and dorsal proteins.

  1992cited by this paper
• RelB, a new Rel family transcription activator that can interact with p50-NF-kappa B

  1992cited by this paper
• A novel mitogen-inducible gene product related to p50/p105-NF-kappa B participates in transactivation through a kappa B site

  1992cited by this paper
• The precursor of NF-kappa B p50 has I kappa B-like functions.

  1992cited by this paper
• Structural and functional analysis of oncogenes and tumor suppressor genes in adult T-cell leukemia/lymphoma shows frequent p53 mutations.

  1992cited by this paper
• The candidate oncoprotein Bcl-3 is an antagonist of pSO/NF-κB-mediated inhibition

  1992cited by this paper
• The NF‐kappa B p50 precursor, p105, contains an internal I kappa B‐like inhibitor that preferentially inhibits p50.

  1992cited by this paper
• The candidate oncoprotein Bcl-3 is an antagonist of p50/NF-kappa B-mediated inhibition.

  1992cited by this paper
• Interaction of HTLV-1 Tax1 with p67SRF causes the aberrant induction of cellular immediate early genes through CArG boxes.

  1992cited by this paper
• Human T-cell lymphotropic virus type I (HTLV-I) transcriptional activator, Tax, enhances CREB binding to HTLV-I 21-base-pair repeats by protein-protein interaction.

  1992cited by this paper
• I kappa B gamma, a 70 kd protein identical to the C-terminal half of p110 NF-kappa B: a new member of the I kappa B family.

  1992cited by this paper
• Transcriptional activator Tax of HTLV-1 binds to the NF-kappa B precursor p105.

  1992cited by this paper
• Molecular cloning and characterization of a novel Rel/NF-kappa B family member displaying structural and functional homology to NF-kappa B p50/p105.

  1992cited by this paper
• The p65 subunit is responsible for the strong transcription activating potential of NF‐kappa B.

  1991cited by this paper
• Type I human T cell leukemia virus tax protein transforms rat fibroblasts through the cyclic adenosine monophosphate response element binding protein/activating transcription factor pathway.

  1991cited by this paper
• Malignant transformation by mutant Rel proteins.

  1991cited by this paper
• Generation of p50 subunit of NF-kB by processing of p105 through an ATP-dependent pathway

  1991cited by this paper
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  1991cited by this paper
• DNA binding and IκB inhibition of the cloned p65 subunit of NF-κB, a rel-related polypeptide

  1991cited by this paper
• Cloning of the DNA-binding subunit of human nuclear factor kappa B: the level of its mRNA is strongly regulated by phorbol ester or tumor necrosis factor alpha.

  1991cited by this paper
• Cloning of an NF-κB subunit which stimulates HIV transcription in synergy with p65

  1991cited by this paper
• Interaction of the human T-cell lymphotrophic virus type I (HTLV-I) transcriptional activator Tax with cellular factors that bind specifically to the 21-base-pair repeats in the HTLV-I enhancer.

  1991cited by this paper
• B cell lymphoma-associated chromosomal translocation involves candidate oncogene lyt-10, homologous to NF-kappa B p50.

  1991cited by this paper
• Four regulatory elements in the human c-fos promoter mediate transactivation by HTLV-1 Tax protein.

  1991cited by this paper
• DNA binding and I kappa B inhibition of the cloned p65 subunit of NF-kappa B, a rel-related polypeptide.

  1991cited by this paper
• Molecular biology of the type I human T-cell leukemia virus (HTLV-I) and adult T-cell leukemia.

  1991cited by this paper
• Isolation of a rel-related human cDNA that potentially encodes the 65-kD subunit of NF-kappa B.

  1991cited by this paper
• Cloning of an NF-kappa B subunit which stimulates HIV transcription in synergy with p65.

  1991cited by this paper
• Binding of the HTLV‐I Tax1 transactivator to the inducible 21 bp enhancer is mediated by the cellular factor HEB1.

  1991cited by this paper
• The inducible transcription activator NF-kappa B: regulation by distinct protein subunits.

  1991cited by this paper
• The inducible transcription activator NF-κB: regulation by distinct protein subunits

  1991cited by this paper
• Regulation of human T cell leukemia virus expression 1

  1990cited by this paper
• The candidate proto-oncogene bcl-3 is related to genes implicated in cell lineage determination and cell cycle control.

  1990cited by this paper
• Cloning of a mitogen-inducible gene encoding a κB DNA-binding protein with homology to the rel oncogene and to cell-cycle motifs

  1990cited by this paper
• NF-kappa B, KBF1, dorsal, and related matters.

  1990cited by this paper
• The human T-lymphotropic virus type I tax gene can cooperate with the ras oncogene to induce neoplastic transformation of cells

  1990cited by this paper
• Identification of HTLV-I tax trans-activator mutants exhibiting novel transcriptional phenotypes.

  1990cited by this paper
• Cloning of the p50 DNA binding subunit of NF-kappa B: homology to rel and dorsal.

  1990cited by this paper
• Oncogenic transformation by the tax gene of human T-cell leukemia virus type I in vitro.

  1990cited by this paper
• The 65-kD subunit of NF-kappa B is a receptor for I kappa B and a modulator of DNA-binding specificity.

  1990cited by this paper
• Purified human I kappa B can rapidly dissociate the complex of the NF-kappa B transcription factor with its cognate DNA.

  1990cited by this paper
• The DNA binding subunit of NF-κB is identical to factor KBF1 and homologous to the rel oncogene product

  1990cited by this paper
• Purified human IκB can rapidly dissociate the complex of the NF-κB transcription factor with its cognate DNA

  1990cited by this paper
• Cloning of the p50 DNA binding subunit of NF-κB: Homology to rel and dorsal

  1990cited by this paper
• Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme.

  1989cited by this paper
• Activation of endogenous c-fos proto-oncogene expression by human T-cell leukemia virus type I-encoded p40tax protein in the human T-cell line, Jurkat

  1989cited by this paper
• UV-induced DNA damage is an intermediate step in UV-induced expression of human immunodeficiency virus type 1, collagenase, c-fos, and metallothionein

  1989cited by this paper
• Stimulation of the human immunodeficiency virus type 1 enhancer by the human T-cell leukemia virus type I tax gene product involves the action of inducible cellular proteins

  1989cited by this paper
• A human rel proto-oncogene cDNA containing an Alu fragment as a potential coding exon.

  1989cited by this paper
• A 65-kappaD subunit of active NF-kappaB is required for inhibition of NF-kappaB by I kappaB.

  1989cited by this paper
• c-fos promoter trans-activation by the tax1 protein of human T-cell leukemia virus type I.

  1988cited by this paper
• I kappa B: a specific inhibitor of the NF-kappa B transcription factor.

  1988cited by this paper
• Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-kappa B transcription factor.

  1988cited by this paper
• Manifestations of human T-lymphotropic virus type I infection.

  1988cited by this paper
• HTLV-I tax induces cellular proteins that activate the kappa B element in the IL-2 receptor alpha gene.

  1988cited by this paper
• Geographic distribution of HTLV‐I and identification of a new high‐risk population

  1988cited by this paper
• Cellular transcription factors and regulation of IL-2 receptor gene expression by HTLV-I tax gene product.

  1988cited by this paper
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  1987cited by this paper
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  1987cited by this paper
• Non-Hodgkin lymphoma in Jamaica and its relation to adult T-cell leukemia-lymphoma.

  1987cited by this paper
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  1987cited by this paper
• The tat gene of human T-lymphotropic virus type 1 induces mesenchymal tumors in transgenic mice.

  1987cited by this paper
• A transgenic mouse model for human neurofibromatosis.

  1987cited by this paper
• Regulation of the human interleukin-2 receptor alpha chain promoter: activation of a nonfunctional promoter by the transactivator gene of HTLV-I.

  1987cited by this paper
• Dorsal, an embryonic polarity gene in Drosophila, is homologous to the vertebrate proto-oncogene, c-rel.

  1987cited by this paper
• Induction of interleukin 2 receptor gene expression by p40x encoded by human T‐cell leukemia virus type 1.

  1986cited by this paper
• HTLV-I associated myelopathy, a new clinical entity.

  1986cited by this paper
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  1986cited by this paper
• The x gene is essential for HTLV replication.

  1985cited by this paper
• A transcriptional activator protein encoded by the x-lor region of the human T-cell leukemia virus.

  1985cited by this paper
• Antibodies to human T-lymphotropic virus type-I in patients with tropical spastic paraparesis.

  1985cited by this paper
• Nucleic acid sequences of the oncogene v-rel in reticuloendotheliosis virus strain T and its cellular homolog, the proto-oncogene c-rel

  1984cited by this paper
• The pathologic spectrum of adult T‐cell leukemia/lymphoma in the United States: Human T‐cell leukemia/lymphoma virus‐associated lymphoid malignancies

  1984cited by this paper
• Epidemiology of human T-cell leukemia/lymphoma virus.

  1983cited by this paper
• Association of the human type C retrovirus with a subset of adult T-cell cancers.

  1983cited by this paper
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  1983cited by this paper
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  1982cited by this paper
• The human type‐C retrovirus, HTLV, in blacks from the Caribbean region, and relationship to adult T‐cell leukemia/lymphoma

  1982cited by this paper
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  1982cited by this paper
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  1982cited by this paper
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  1977cited by this paper
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