Gastrointestinal effects of nonsteroidal anti‐inflammatory drugs

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Fundamental & Clinical Pharmacology

• Publication date

  2003-06-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1046/j.1472-8206.2003.00135.xPMID 12803569
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Endoscopic evaluation of etodolac and naproxen, and their relative effects on gastric and duodenal prostaglandins

  2005cited by this paper
• Presents from patient

  2002cited by this paper
• UvA-DARE (Digital Academic Repository) Are selective COX 2 inhibitors superior to traditional non steroidal anti-inflammatory drugs?

  2002cited by this paper
• Pharmacology and potential therapeutic applications of nitric oxide‐releasing non‐steroidal anti‐inflammatory and related nitric oxide‐donating drugs

  2002cited by this paper
• Comparison of thromboembolic events in patients treated with celecoxib, a cyclooxygenase-2 specific inhibitor, versus ibuprofen or diclofenac.

  2002cited by this paper
• Observational study of upper gastrointestinal haemorrhage in elderly patients given selective cyclo-oxygenase-2 inhibitors or conventional non-steroidal anti-inflammatory drugs

  2002cited by this paper
• COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: Cloning, structure, and expression

  2002cited by this paper
• Efficacy, tolerability, and upper gastrointestinal safety of celecoxib for treatment of osteoarthritis and rheumatoid arthritis: systematic review of randomised controlled trials

  2002cited by this paper
• Risk of cardiovascular events associated with selective COX-2 inhibitors.

  2001cited by this paper
• Interactive roles of superoxide and inducible nitric oxide synthase in rat intestinal injury provoked by non-steroidal anti-inflammatory drugs.

  2001cited by this paper
• The coxibs, selective inhibitors of cyclooxygenase-2.

  2001cited by this paper
• Inhibition of bone resorption in vitro and prevention of ovariectomy-induced bone loss in vivo by flurbiprofen nitroxybutylester (HCT1026).

  2001cited by this paper
• Cyclooxygenase 2—implications on maintenance of gastric mucosal integrity and ulcer healing: controversial issues and perspectives

  2001cited by this paper
• COX-2 inhibition with rofecoxib does not increase intestinal permeability in healthy subjects: a double blind crossover study comparing rofecoxib with placebo and indomethacin

  2000cited by this paper
• Nitrovasodilators, low-dose aspirin, other nonsteroidal antiinflammatory drugs, and the risk of upper gastrointestinal bleeding.

  2000cited by this paper
• NO‐naproxen modulates inflammation, nociception and downregulates T cell response in rat Freund's adjuvant arthritis

  2000cited by this paper
• Incidence of congenital rubella in Greece

  2000cited by this paper
• Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: the CLASS study: A randomized controlled trial. Celecoxib Long-term Arthritis Safety Study.

  2000cited by this paper
• NSAID-induced gastric damage in rats: requirement for inhibition of both cyclooxygenase 1 and 2.

  2000cited by this paper
• Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group.

  2000cited by this paper
• Comparative efficacy and safety of nimesulide and diclofenac in patients with acute shoulder, and a meta-analysis of controlled studies with nimesulide.

  1999cited by this paper
• Suppression of inducible cyclooxygenase 2 gene transcription by aspirin and sodium salicylate.

  1999cited by this paper
• The in vivo assessment of nimesulide cyclooxygenase-2 selectivity.

  1999cited by this paper
• Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: the human pharmacology of a selective inhibitor of COX-2.

  1999cited by this paper
• Celecoxib versus diclofenac in long-term management of rheumatoid arthritis: randomised double-blind comparison.

  1999cited by this paper
• Adverse upper gastrointestinal effects of rofecoxib compared with NSAIDs.

  1999cited by this paper
• Rofecoxib [Vioxx, MK-0966; 4-(4'-methylsulfonylphenyl)-3-phenyl-2-(5H)-furanone]: a potent and orally active cyclooxygenase-2 inhibitor. Pharmacological and biochemical profiles.

  1999cited by this paper
• Anti-inflammatory and upper gastrointestinal effects of celecoxib in rheumatoid arthritis: a randomized controlled trial.

  1999cited by this paper
• Selective cyclo‐oxygenase‐2 inhibitors aggravate ischaemia‐reperfusion injury in the rat stomach

  1999cited by this paper
• Nitric oxide, superoxide radicals and mast cells in pathogenesis of indomethacin-induced small intestinal lesions in rats.

  1999cited by this paper
• A randomized trial comparing the effect of rofecoxib, a cyclooxygenase 2-specific inhibitor, with that of ibuprofen on the gastroduodenal mucosa of patients with osteoarthritis. Rofecoxib Osteoarthritis Endoscopy Study Group.

  1999cited by this paper
• Cyclo‐oxygenase‐2: pharmacology, physiology, biochemistry and relevance to NSAID therapy

  1999cited by this paper
• Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis.

  1999cited by this paper
• Lack of beneficial effect of COX-2 inhibitors in an experimental model of colitis.

  1999cited by this paper
• Use of point-of-care test in identification of patients who can benefit from desmopressin during cardiac surgery: a randomised controlled trial.

  1999cited by this paper
• Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: Insight into mechanisms and implications for cancer growth and ulcer healing

  1999cited by this paper
• Gastrointestinal safety of nitric oxide-derived aspirin is related to inhibition of ICE-like cysteine proteases in rats.

  1999cited by this paper
• COX-2 inhibitors.

  1999cited by this paper
• Pharmacological approach to the prevention of non-steroidal anti-inflammatory drug-induced gastropathy.

  1999cited by this paper
• COX-2 inhibitors.

  1999cited by this paper
• Levels of cyclooxygenase-1 and -2 mRNA expression at various stages of acute gastric injury induced by ischemia-reperfusion in rats.

  1998cited by this paper
• Role of tumour necrosis factor-alpha and inducible nitric oxide synthase in the prevention of nitro-flurbiprofen small intestine toxicity.

  1998cited by this paper
• Gastrointestinal tolerability of meloxicam compared to diclofenac in osteoarthritis patients. International MELISSA Study Group. Meloxicam Large-scale International Study Safety Assessment.

  1998cited by this paper
• Comparison of indomethacin and nimesulide, a selective cyclooxygenase-2 inhibitor, on key pathophysiologic steps in the pathogenesis of nonsteroidal anti-inflammatory drug enteropathy in the rat.

  1998cited by this paper
• Intestinal permeability and inflammation in patients on NSAIDs

  1998cited by this paper
• Effects of inhibition of prostaglandin endoperoxide synthase‐2 in chronic gastro‐intestinal ulcer models in rats

  1998cited by this paper
• Improvement in gastrointestinal tolerability of the selective cyclooxygenase (COX)-2 inhibitor, meloxicam, compared with piroxicam: results of the Safety and Efficacy Large-scale Evaluation of COX-inhibiting Therapies (SELECT) trial in osteoarthritis.

  1998cited by this paper
• Nonsteroidal anti-inflammatory drug enteropathy in rats: role of permeability, bacteria, and enterohepatic circulation.

  1997cited by this paper
• Nonsteroidal anti-inflammatory drugs and gastroenteropathy: the second hundred years.

  1997cited by this paper
• Exacerbation of inflammation-associated colonic injury in rat through inhibition of cyclooxygenase-2.

  1996cited by this paper
• Indomethacin-induced lesion modifies contractile activity in rat small intestines.

  1995cited by this paper
• Role of tumor necrosis factor alpha release and leukocyte margination in indomethacin-induced gastric injury in rats.

  1995cited by this paper
• Non-steroidal anti-inflammatory drugs (NSAIDs) associate with zwitterionic phospholipids: Insight into the mechanism and reversal of NSAID-induced gastrointestinal injury

  1995cited by this paper
• Transdermal nitroglycerin prevents nonsteroidal anti-inflammatory drug gastropathy.

  1995cited by this paper
• The biochemical basis of non-steroidal anti-inflammatory drug-induced damage to the gastrointestinal tract: a review and a hypothesis.

  1995cited by this paper
• Double-blind, placebo-controlled comparison of the safety and efficacy of orally administered etodolac and nabumetone in patients with active osteoarthritis of the knee.

  1995cited by this paper
• Induction of nitric oxide synthase and microvascular injury in the rat jejunum provoked by indomethacin

  1995cited by this paper
• Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration.

  1995cited by this paper
• Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic.

  1994cited by this paper
• Risks of bleeding peptic ulcer associated with individual non-steroidal anti-inflammatory drugs.

  1994cited by this paper
• A diclofenac derivative without ulcerogenic properties.

  1994cited by this paper
• Double-blind, randomised, multi-centre clinical study evaluating the efficacy and tolerability of nimesulide in comparison with etodalac in patients suffering from osteoarthritis of the knee.

  1994cited by this paper
• The microcirculation and inflammation: modulation of leukocyte‐endothelial cell adhesion

  1994cited by this paper
• Neuronal and endothelium‐derived mediators in the modulation of the gastric microcirculation: integrity in the balance

  1993cited by this paper
• Role of endothelial adhesion molecules in NSAID-induced gastric mucosal injury.

  1993cited by this paper
• Modulation of leukocyte adhesion in rat mesenteric venules by aspirin and salicylate.

  1992cited by this paper
• Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing.

  1991cited by this paper
• A serum- and glucocorticoid-regulated 4-kilobase mRNA encodes a cyclooxygenase-related protein.

  1991cited by this paper
• Oxygen Free Radicals and Lipid Peroxidation in the Pathogenesis of Gastric Mucosal Lesions Induced by Indomethacin in Rats

  1991cited by this paper
• Oxygen free radicals and lipid peroxidation in the pathogenesis of gastric mucosal lesions induced by indomethacin in rats. Relation to gastric hypermotility.

  1991cited by this paper
• Role of oxygen-derived free radicals in indomethacin-induced gastric injury.

  1991cited by this paper
• The induction and suppression of prostaglandin H2 synthase (cyclooxygenase) in human monocytes.

  1990cited by this paper
• Regulation of gastric mucosal integrity by endogenous nitric oxide: interactions with prostanoids and sensory neuropeptides in the rat

  1990cited by this paper
• Gastric ulceration induced by nonsteroidal anti-inflammatory drugs is a neutrophil-dependent process.

  1990cited by this paper
• Internalization of fluorescent vasotocin-receptor agonist and antagonist in the toad bladder.

  1990cited by this paper
• Human gastric mucosal bleeding induced by low dose aspirin, but not warfarin.

  1989cited by this paper
• Toward an epidemiology of gastropathy associated with nonsteroidal antiinflammatory drug use.

  1989cited by this paper
• Vascular injury in acute gastric mucosal damage

  1988cited by this paper
• The role of leukotrienes in the pathogenesis of gastric ulceration.

  1988cited by this paper
• Indomethacin inhibits duodenal mucosal bicarbonate secretion and endogenous prostaglandin E2 output in human subjects.

  1987cited by this paper
• Effect of aspirin plus hydrochloric acid on the gastric mucosal microcirculation.

  1987cited by this paper
• Nonsteroidal antiinflammatory drug-induced intestinal inflammation in humans.

  1987cited by this paper
• Free radicals and lipid peroxidation in ethanol- or aspirin-induced gastric mucosal injury

  1987cited by this paper
• Effect of acetylsalicylic acid on gastric mucin viscosity, permeability to hydrogen ion, and susceptibility to pepsin.

  1986cited by this paper
• Butyl hydroxy toluene antagonizes the gastric toxicity but not the pharmacological activity of acetylsalicylic acid in rats

  1984cited by this paper
• Temporal Relationship Between Cyclooxygenase Inhibition, as Measured by Prostacyclin Biosynthesis, and the Gastrointestinal Damage Induced by Indomethacin in the Rat

  1981cited by this paper
• Temporal relationship between cyclooxygenase inhibition, as measured by prostacyclin biosynthesis, and the gastrointestinal damage induced by indomethacin in the rat.

  1981cited by this paper
• Intravenous indomethacin and aspirin reduce basal gastric mucosal blood flow in dogs.

  1980cited by this paper
• Anti-inflammatory/anti-pyretic salicylic acid esters with low gastric ulcerogenic activity

  1980cited by this paper
• Selective inhibition of prostaglandin production in inflammatory exudates and gastric mucosa

  1980cited by this paper
• Cytoprotection by Prostaglandins in Rats Prevention of Gastric Necrosis Produced by Alcohol, HCl, NaOH, Hypertonic NaCl, and Thermal Injury

  1979cited by this paper
• Cytoprotection by prostaglandins in rats. Prevention of gastric necrosis produced by alcohol, HCl, NaOH, hypertonic NaCl, and thermal injury.

  1979cited by this paper
• Effect of indomethacin and aspirin on gastric blood flow and acid secretion.

  1977cited by this paper
• Salicylate- and aspirin-induced uncoupling of oxidative phosphorylation in mitochondria isolated from the mucosal membrane of the stomach.

  1976cited by this paper
• INVESTIGATION OF THE VASODILATOR AND ANTISECRETORY ROLE OF PROSTAGLANDINS IN THE RAT GASTRIC MUCOSA BY USE OF NON‐STEROIDAL ANTI‐INFLAMMATORY DRUGS

  1975cited by this paper
• Effect of aspirin on ionic movement and acid hydrolase activity of explants of canine antral and duodenal mucosae.

  1975cited by this paper
• An intestinal disease produced experimentally by a prostaglandin deficiency.

  1975cited by this paper
• Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs.

  1971cited by this paper
• Profile of pH, pressure, and potential difference at gastroduodenal junction in man.

  1965cited by this paper
• Concerning the regulation of some diverse biochemical reactions underlying the inflammatory response by salicylic acid, phenylbutazone and other acidic antirheumatic drugs

  1965cited by this paper

• Gastroprotective and Antioxidant Effects of Ferula Plant Extract Against Indomethacin Induced Gastric Ulcer in Rats

  2025cites this paper
• Pharmacological insight of rutin as a potential candidate against peptic ulcer.

  2024cites this paper
• Effect of phylloquinone on indomethacin‐induced gastric ulceration in rats: Role of SIRT‐1

  2023cites this paper
• The severity of NEC is ameliorated by prostaglandin E2 through regulating intestinal microcirculation

  2023cites this paper
• An Exploratory Study Investigating the Prevalence of Gastrointestinal Symptoms in Collegiate Division I American Football Athletes

  2023cites this paper
• Regular use of low-dose of opioids after gastrointestinal surgery may lead to postoperative gastrointestinal tract dysfunction in children: a Chinese national regional health center experience sharing

  2023cites this paper
• PEPTIC ULCER: A SURVEY ON ETIOLOGY AND PATHOGENESIS

  2023cites this paper
• Protective Effects of Aqueous Extracts of the Herb of Paederia scandens (Lour.) Merr. against HCl/EtOH-Induced Gastric Ulcer in Rats: Involvement and Inhibitors’ Identification of NF-κB Signaling

  2023cites this paper
• Potential metabolites of Arecaceae family for the natural anti-osteoarthritis medicine: A review

  2022cites this paper
• Non-steroidal anti-inflammatory drugs (NSAIDs), pain and aging: Adjusting prescription to patient features.

  2022cites this paper
• Protective effect of Juglans regia L. (walnut) leaves extract against indomethacin induced gastric mucosal damage in rats

  2022cites this paper
• Naproxen sodium nanoparticles are less toxic and gastroprotective agents than the conventional NSAID drug naproxen sodium in Balb/c mice.

  2022cites this paper
• Three-dimensional printed dosage forms based on disease-focussed perspectives.

  2022cites this paper
• Efficacy of olmesartan, irbesartan and telmisartan against acute indomethacin-induced gastric ulcers in mice

  2022cites this paper
• Synthesis of PVA capped naproxen conjugated MgO nanoparticles and its bioactivity screening

  2022cites this paper
• Histopathological Overview of Experimental Ulcer Models

  2022cites this paper
• Ketogal Safety Profile in Human Primary Colonic Epithelial Cells and in Mice

  2021cites this paper
• A narrative review

  2021cites this paper
• A Novel approach to develop Etodolac Emulgel with Alkaloidal Penetration Enhancer

  2021cites this paper
• Phase transited asymmetric membrane floating nanoparticles: a means for better management of poorly water-soluble drugs

  2021cites this paper
• Ameliorative effects of ribes rubrum oil against gastric ulcers caused by indomethacin in experimental models

  2021cites this paper
• GASTROPROTECTIVE ACTIVITY OF BROWN PROPOLIS EXTRACT AGAINST ASPIRIN AND ETHANOL- INDUCED GASTRIC ULCERS IN ADULT WISTAR RATS BY TARGETING OXIDATIVE STRESS AND PRO-INFLAMMATORY SIGNALING

  2020cites this paper
• Polysubstituted Pyrimidines as mPGES-1 Inhibitors: Discovery of Potent Inhibitors of PGE2 Production with a Strong Anti-inflammatory Effects in Carrageenan-Induced Rat Paw Edema.

  2020cites this paper
• Carvedilol safeguards against aspirin-induced gastric damage in rats

  2020cites this paper
• Antiulcerogenic effect of Capparis cartillaginea decne on indomethacin induced gastric ulcer in wistar rats

  2020cites this paper
• Synthesis, in silico studies and cytotoxicity evaluation of novel 1,3,4-oxadiazole derivatives designed as potential mPGES-1 inhibitors

  2020cites this paper
• The Effect of Metformin on Indomethacin-induced Gastric Ulcer: Involvement of Nitric oxide/Rho kinase pathway.

  2020cites this paper
• Modulating Effect of Vitamin D on iNOS, PCNA and a-SMA Expression Against Diclofenac Sodium Induced Gastric Injury in Rats

  2020cites this paper
• Gastric Perforation Associated with Candidiasis and NSAIDS

  2020cites this paper
• COMPARATIVE GASTROPROTECTIVE ACTIVITY OF Malva pseudolavatera Webb & Berthel and Malva sylvestris L. GROWN IN ECUADOR

  2020cites this paper
• A Straightforward Approach to the Synthesis of Disubstituted Cyclopentenones

  2020cites this paper
• Preparation and evaluation of protective effect of pumpkin seed oil based self nanoemulsifying oral delivery system against ibuprofen-induced peptic ulcer

  2019cites this paper
• A randomized clinical efficacy study targeting mPGES1 or EP4 in dogs with spontaneous osteoarthritis

  2019cites this paper
• Relationships between housing and management factors and clinical health events in elephants in North American zoos

  2019cites this paper
• Penetration and efficacy of transdermal NSAIDs in a model of acute joint inflammation

  2018cites this paper
• Efficacy and safety of combined low doses of either diclofenac or celecoxib with gabapentin versus their single high dose in treatment of neuropathic pain in rats.

  2018cites this paper
• Gastro-protective effect of methanol extract of Vernonia amygdalina (del.) leaf on aspirin-induced gastric ulcer in Wistar rats

  2017cites this paper
• New pyrazole derivative 5‐[1‐(4‐fluorophenyl)‐1H‐pyrazol‐4‐yl]‐2H‐tetrazole: synthesis and assessment of some biological activities

  2017cites this paper
• Pulmonary , gastrointestinal and urogenital pharmacology Participation of the anti-in fl ammatory and antioxidative activity of docosahexaenoic acid on indomethacin-induced gastric injury model

  2017cites this paper
• Nonsteroidal Anti-Inflammatory Drugs: Exploiting Bivalent COXIB/ TP Antagonists for the Control of Cardiovascular Risk.

  2017influential citation
• Complementarity of in vitro and in vivo models for the evaluation of gastro‐protective effects of pharmacological substances

  2017cites this paper
• Pathophysiology of Enteritis and Colitis

  2017cites this paper
• The curative effect of modified Wuqi decoction against non-steroidal antiinflammatory drugs-induced gastric ulcer by regulating the pathway of COX2/PGE2

  2017cites this paper
• THROMBOXANE PROSTANOID RECEPTOR: FUNCTION, ACTIVATION AND POSSIBLE TARGET FOR CARDIOVASCULAR PROTECTION

  2017cites this paper
• Mitigating effect of Avicenna marina on indomethacin induced gastric ulcer in male albino rats

  2016cites this paper
• EVALUATION OF ANTIULCER ACTIVITY OF RED PEPPER AND GARLIC BULB AGAINST INDOMETHACIN- INDUCED GASTRIC ULCER IN RATS: BIOCHEMICAL AND HISTOPATHOLOGICAL STUDY

  2016cites this paper
• Serotonin and histamine mediate gastroprotective effect of fluoxetine against experimentally-induced ulcers in rats

  2016cites this paper
• Synthesis and antinociceptive activity of new 2-substituted 4-(trifluoromethyl)-5,6-dihydrobenzo[h]quinazolines.

  2016cites this paper
• Evaluation of the Antiulcer Activity of the Leaves of Azadirachta indica: An Experimental Study

  2016cites this paper
• ADMINISTRATION OF H2 BLOCKERS IN NSAID INDUCED GASTROPATHY IN RATS: effect on histopathological changes in gastric, hepatic and renal tissues.

  2016cites this paper
• Serotonin and histamine mediate gastroprotective effect of fluoxetine against experimentally-induced ulcers in rats

  2016cites this paper
• Gastroprotective effect of bezafibrate, a peroxisome proliferator activated receptor α agonist and its mechanism in a rat model of aspirin‐induced gastric ulcer

  2016cites this paper
• A REVIEW ON: PEPTIC ULCER

  2016cites this paper
• Antinociceptive and anti-hyperalgesic effects of bis(4-methylbenzoyl) diselenide in mice: Evidence for the mechanism of action

  2015cites this paper
• Gastroprotective effect of andrographolide sodium bisulfite against indomethacin-induced gastric ulceration in rats.

  2015cites this paper
• Evaluation of anti-ulcer, anti-secretory and anti- helicobacter pylori effects of folkloric medicinal plant, Fumaria vaillantii L, in rats

  2015cites this paper
• Activity of Alkaloids on Peptic Ulcer: What’s New?

  2015cites this paper
• Pes Anserine Bursitis in Symptomatic Osteoarthritis Patients: A Mesotherapy Treatment Study

  2015cites this paper
• Antisecretory, Gastroprotective, Antioxidant and Anti-Helicobcter Pylori Activity of Zerumbone from Zingiber Zerumbet (L.) Smith

  2015cites this paper
• The postulated mechanism of the protective effect of ginger on the aspirin induced gastric ulcer: Histological and immunohistochemical studies.

  2015cites this paper
• Antioxidant activity of aqueous extract of Piliostigma thonningii Leaf following Indomethacin induced gastric mucosa onslaught in male wistar Albino Rats.

  2015cites this paper
• Antiulcer activity of Garcinia indica fruit rind (kokum berry) in rats

  2014cites this paper
• A review on COX and their inhibitors: Present and future

  2014cites this paper
• Gastro-protective, Anti-Helicobacter pylori and, Antioxidant Properties of Moroccan Zizyphus lotus L.

  2014cites this paper
• Gastric antisecretory and cytoprotective effects of hydroalcoholic extracts of Plumeria alba Linn. leaves in rats.

  2014cites this paper
• Proanthocyanidin from Grape Seed Extracts Protects Indomethacin-Induced Small Intestinal Mucosal Injury

  2014cites this paper
• Nonsteroidal Anti-inflammatory Drugs and Inflammatory Bowel Disease: Pathophysiology and Clinical Associations

  2014influential citation
• Application of prostaglandin E2 improves ileal blood flow in NEC.

  2014influential citation
• Effects of rifaximin on indomethacin-induced intestinal damage in guinea-pigs.

  2014cites this paper
• Comparative evaluation of gastroulcerogenic potential of nitrogen isoforms of salicyl alcohol and aspirin in rats: biochemical and histological study

  2014cites this paper
• Gastro-protective, Anti-Helicobacter pylori and, Antioxidant Properties of Moroccan Zizyphus lotus L

  2014cites this paper
• Efficacy and Safety of some Medical Herbs on Gastric Ulcer Induced by Aspirin in Rats

  2014cites this paper
• EFFECTS OF THE COMBINED THERAPY D-002 PLUS GRAPE SEED EXTRACT (GSE) ON ASPIRIN INDUCED GASTRIC ULCER IN RATS.

  2014cites this paper
• Management of Rheumatoid Arthritis and Monitoring of Drug Therapy: A Review

  2014cites this paper
• Evaluation of Antiulcer Activity of Ginger, Clove and Castor Oils Against Aspirin Induced Gastric Ulcers in Rats

  2014cites this paper
• PROTECTIVE EFFECT OF ARJUNOLIC ACID (A NATURAL TRITERPENOID SAPONIN OF TERMINALIA ARJUNA (TA)ON ASPIRIN-INDUCED GASTRIC INJURY IN RATS: APOSSIBLE INVOLVEMENT OF INTERCELLULAR ADHESION MOLECULE-1 (ICAM-1) AND VASCULAR ENDOTHELIAL

  2014cites this paper
• Protective effect of Artemisia campestris extract against aspirin-induced gastric lesions and oxidative stress in rat

  2014cites this paper
• 3-Dimensional quantitative structure-activity relationship and molecular docking studies of tetrasubstituted pyrazole derivatives as inhibitors of cyclooxygenase-2

  2014cites this paper
• Investigating the inclusion of the Ag(I)-nimesulide complex into β-cyclodextrin: studies in solution and in the solid state

  2014cites this paper
• Drug-induced injury in the gastrointestinal tract.

  2014cites this paper
• Estimation of ibuprofen in urine and tablet formulations by transmission Fourier Transform Infrared spectroscopy by partial least square.

  2013cites this paper
• Convolutamydine A and synthetic analogues have antinociceptive properties in mice.

  2013cites this paper
• a Noncanonical p38 MAPK Pathway via Cyclooxygenase-2 in Intestinal Epithelium Lipopolysaccharide Induces

  2013cites this paper
• The Interplay Between NSAIDs and Candida albicans on the Gastrointestinal Tract of Guinea Pigs

  2013cites this paper
• Effects of D-002 on Formaldehyde-Induced Osteoarthritis in Rats

  2013cites this paper
• Comparative evaluation of gastroulcerogenic potential of nitrogen isoforms of salicyl alcohol and aspirin in rats: biochemical and histological study

  2013cites this paper
• Antiulcer and gastric antisecretory effects of dichloromethane fraction and piplartine obtained from fruits of Piper tuberculatum Jacq. in rats.

  2013cites this paper
• Influence of ibuprofen addition on the properties of a bioactive bone cement

  2013cites this paper
• Protective Effect of Ginger Against Aspirin-Induced Ulcers in Rats

  2013cites this paper
• In Vivo Models Used for Evaluation of Potential Antigastroduodenal Ulcer Agents

  2013influential citation
• Gastroprotective Effect of L-Carnitine on Indomethacin-Induced Gastric Ulcer in Rats : The Involvement of Antioxidant Mechanisms and Nitric Oxide

  2013cites this paper
• Regular ingestion of cinnamomi cortex pulveratus offers gastroprotective activity in mice

  2013cites this paper
• Efecto del D-002 sobre la úlcera inducida por aspirina asociada al infiltrado de neutrófilos en la mucosa gástrica

  2012cites this paper
• Protective effect of D-002, a mixture of beeswax alcohols, against indomethacin-induced gastric ulcers and mechanism of action

  2012cites this paper
• Lead compound design for TPR/COX dual inhibition

  2012cites this paper
• Semi-solid topical formulations containing nimesulide-loaded nanocapsules showed in-vivo anti-inflammatory activity in chronic arthritis and fibrovascular tissue models

  2012cites this paper
• Loss of Consciousness Induced by a Single Dose Flurbiprofen

  2012cites this paper
• EFFECT OF FLUNIXIN ON OVARIAN CANCER INDUCED BY DMBA IN FEMALE WISTAR RATS

  2012cites this paper
• UNIVERSIDADE FEDERAL DE PERNAMBUCO PROGRAMA DE PÓS-GRADUAÇÃO EM CIÊNCIAS BIOLÓGICAS DEPARTAMENTO DE BIOQUÍMICA

  2012cites this paper
• Avaliação da atividade anti-inflamatória e antinociceptiva do extrato hidroalcoólico de Eugenia punicifolia (Kunth) DC

  2012cites this paper