Adenylyl cyclases: structure, regulation and function in an enzyme superfamily.

No abstract is available for this paper.

• Publication year

  1997

• Venue

  Molecular and Cellular Endocrinology

• Publication date

  1997-04-04

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/S0303-7207(97)04013-6PMID 9140089
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• mu-Opioid receptors inhibit dopamine-stimulated activity of type V adenylyl cyclase but enhance dopamine-stimulated activity of type VII adenylyl cyclase.

  1996cited by this paper
• Purification and Characterization of a Soluble Form of Mammalian Adenylyl Cyclase*

  1996cited by this paper
• Circadian rhythm in the Ca2+‐inhibitable adenylyl cyclase activity of the rat striatum

  1996cited by this paper
• Interaction of the two cytosolic domains of mammalian adenylyl cyclase.

  1996cited by this paper
• Isoform-specific sensitization of adenylyl cyclase activity by prior activation of inhibitory receptors: role of beta gamma subunits in transducing enhanced activity of the type VI isoform.

  1996cited by this paper
• Circadian rhythm in the Ca(2+)-inhibitable adenylyl activity of the rat striatum.

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• Membrane potential regulates sea urchin sperm adenylylcyclase.

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• Diurnal variation of the adenylyl cyclase type 1 in the rat pineal gland.

  1996cited by this paper
• Diversity and selectivity of receptor-G protein interaction.

  1996cited by this paper
• Functional Co-localization of Transfected Ca2+-stimulable Adenylyl Cyclases with Capacitative Ca2+ Entry Sites (*)

  1996cited by this paper
• Agonist regulation of adenylate cyclase activity in neuroblastoma x glioma hybrid NG108-15 cells transfected to co-express adenylate cyclase type II and the beta 2-adrenoceptor. Evidence that adenylate cyclase is the limiting component for receptor-mediated stimulation of adenylate cyclase activity.

  1996cited by this paper
• Reduction of Morphine Abstinence in Mice with a Mutation in the Gene Encoding CREB

  1996cited by this paper
• A Domain on the G Protein β Subunit Interacts with Both Adenylyl Cyclase 2 and the Muscarinic Atrial Potassium Channel*

  1996cited by this paper
• Chronic Opioid Treatment Induces Adenylyl Cyclase V Superactivation

  1996cited by this paper
• Retinal–specific guanylate cyclase gene mutations in Leber's congenital amaurosis

  1996cited by this paper
• Inhibition of Adenylyl Cyclase by a Family of Newly Synthesized Adenine Nucleoside 3′-Polyphosphates*

  1996cited by this paper
• Complexity and diversity of mammalian adenylyl cyclases.

  1996cited by this paper
• Calcineurin Mediates Calcium-induced Potentiation of Adenylyl Cyclase Activity in Dispersed Chief Cells from Guinea Pig Stomach

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• Platelet adenylyl cyclase activity in alcoholics and subtypes of alcoholics. WHO/ISBRA Study Clinical Centers.

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• Families of adenylate cyclase genes in Trypanosoma brucei.

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• Identification and Characterization of a Widely Expressed Form of Adenylyl Cyclase*

  1996cited by this paper
• Phosphorylation and Inhibition of Type III Adenylyl Cyclase by Calmodulin-dependent Protein Kinase II in Vivo *

  1996cited by this paper
• Splice Variants of Type VIII Adenylyl Cyclase

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• Multiplicity in type V adenylylcyclase: type V-a and type V-b.

  1995cited by this paper
• Distinct Characteristics of the Basal Activities of Adenylyl Cyclases 2 and 6 (*)

  1995cited by this paper
• A region of adenylyl cyclase 2 critical for regulation by G protein beta gamma subunits.

  1995cited by this paper
• Altered behavior and long-term potentiation in type I adenylyl cyclase mutant mice.

  1995cited by this paper
• Expression of adenylyl cyclase subtypes in brown adipose tissue: neural regulation of type III.

  1995cited by this paper
• Mapping of adenylyl cyclase genes type I, II, III, IV, V, and VI in mouse

  1995cited by this paper
• Control of a novel adenylyl cyclase by calcineurin.

  1995cited by this paper
• Adenylylcyclase Supersensitization in μ-Opioid Receptor-transfected Chinese Hamster Ovary Cells Following Chronic Opioid Treatment (*)

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• Expression of Type V Adenylyl Cyclase Is Required for Epidermal Growth Factor-mediated Stimulation of cAMP Accumulation (*)

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• Developmentally Expressed Ca2+-sensitive Adenylyl Cyclase Activity Is Disrupted in the Brains of Type I Adenylyl Cyclase Mutant Mice (*)

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• Trypanosoma brucei: stimulation of adenylate cyclase by proventriculus and esophagus tissue of the tsetse fly, Glossina morsitans morsitans.

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• Quantification of signalling components and amplification in the beta-adrenergic-receptor-adenylate cyclase pathway in isolated adult rat ventricular myocytes.

  1995cited by this paper
• Selective effects of ethanol on the generation of cAMP by particular members of the adenylyl cyclase family.

  1995cited by this paper
• Construction of a soluble adenylyl cyclase activated by Gs alpha and forskolin.

  1995cited by this paper
• Acylation of adenylyl cyclase catalyst is important for enzymic activity

  1995cited by this paper
• Localization of the gene for a novel human adenylyl cyclase (ADCY7) to chromosome 16

  1995cited by this paper
• Mammalian Membrane-bound Adenylyl Cyclases (*)

  1995cited by this paper
• Type V, but not type VI, adenylyl cyclase mRNA accumulates in the rat heart during ontogenic development. Correlation with increased global adenylyl cyclase activity.

  1995cited by this paper
• Regulation of cellular calcium through signaling cross‐talk involves an intricate interplay between the actions of receptors, G‐proteins, and second messengers

  1995cited by this paper
• Identification of Functional Domains of Adenylyl Cyclase Using in Vivo Chimeras (*)

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• Adenylyl cyclases and the interaction between calcium and cAMP signalling

  1995cited by this paper
• Ca2+ Inhibition of Type III Adenylyl Cyclase in Vivo(*)

  1995cited by this paper
• Hormone Stimulation of Type III Adenylyl Cyclase Induces Ca2+ Oscillations in HEK-293 Cells (*)

  1995cited by this paper
• Voltage-sensitive Adenylyl Cyclase Activity in Cultured Neurons. A CALCIUM-INDEPENDENT PHENOMENON (*)

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• Regulation of Adenylyl Cyclase by Protein Kinase A (*)

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• Stimulation of cAMP accumulation by the cloned Xenopus melatonin receptor through Gi and Gz proteins

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• G protein beta gamma subunits. Simplified purification and properties of novel isoforms.

  1994cited by this paper
• Chromosomal mapping of human adenylyl cyclase genes type III, type V and type VI

  1994cited by this paper
• Molecular cloning of the human type VIII adenylyl cyclase

  1994cited by this paper
• Changes in type VI adenylyl cyclase isoform expression correlate with a decreased capacity for cAMP generation in the aging ventricle.

  1994cited by this paper
• A novel peptide inhibitor of adenylyl cyclase (AC). A peptide from type V AC directly inhibits AC catalytic activity.

  1994cited by this paper
• Type VIII adenylyl cyclase. A Ca2+/calmodulin-stimulated enzyme expressed in discrete regions of rat brain.

  1994cited by this paper
• Differential activation of adenylyl cyclase by protein kinase C isoenzymes.

  1994cited by this paper
• Bimodal Opioid Regulation of Cyclic AMP Formation: Implications for Positive and Negative Coupling of Opiate Receptors to Adenylyl Cyclase

  1994cited by this paper
• Protein kinase C-dependent cyclic AMP formation in airway smooth muscle: the role of type II adenylate cyclase and the blockade of extracellular-signal-regulated kinase-2 (ERK-2) activation.

  1994cited by this paper
• Evidence for participation of calcineurin in potentiation of agonist-stimulated cyclic AMP formation by the calcium-mobilizing hormone, angiotensin II.

  1994cited by this paper
• Capacitative Ca2+ entry regulates Ca(2+)-sensitive adenylyl cyclases.

  1994cited by this paper
• Ca(2+)-sensitive adenylyl cyclases.

  1994cited by this paper
• Phorbol ester-induced stimulation and phosphorylation of adenylyl cyclase 2.

  1994cited by this paper
• Mammalian adenylyl cyclase family members are randomly located on different chromosomes

  1994cited by this paper
• Regulation of forskolin interactions with type I, II, V, and VI adenylyl cyclases by Gs alpha.

  1994cited by this paper
• Ca(2+)-sensitive adenylyl cyclases.

  1994cited by this paper
• G protein βγ subunits: Simplified purification and properties of novel isoforms

  1994cited by this paper
• Colocalization of the genes coding for the alpha 3 and beta 3 subunits of soluble guanylyl cyclase to human chromosome 4 at q31.3-q33.

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• In vivo generation of an adenylylcyclase isoform with a half-molecule motif.

  1993cited by this paper
• Type I Calmodulin‐Sensitive Adenylyl Cyclase Is Neural Specific

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  1993cited by this paper
• Inhibition of adenylyl cyclase by Gi alpha.

  1993cited by this paper
• Stimulation of specific types of Gs-stimulated adenylyl cyclases by phorbol ester treatment.

  1993cited by this paper
• The calmodulin binding domain of nitric oxide synthase and adenylyl cyclase.

  1993cited by this paper
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• Cloning and expression of an adenylyl cyclase localized to the corpus striatum

  1993cited by this paper
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• Stimulation of Trypanosoma cruzi adenylyl cyclase by an alpha D-globin fragment from Triatoma hindgut: effect on differentiation of epimastigote to trypomastigote forms.

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• Modification of the calcium and calmodulin sensitivity of the type I adenylyl cyclase by mutagenesis of its calmodulin binding domain.

  1993cited by this paper
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  1992cited by this paper
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• Different chromosomal localization of two adenylyl cyclase genes expressed in human brain

  1992cited by this paper
• The Drosophila learning and memory gene rutabaga encodes a Ca2+/Calmodulin-responsive adenylyl cyclase.

  1992cited by this paper
• Isolation and characterization of a novel cardiac adenylylcyclase cDNA.

  1992cited by this paper
• Two members of a widely expressed subfamily of hormone-stimulated adenylyl cyclases.

  1992cited by this paper
• Molecular diversity in the adenylylcyclase family. Evidence for eight forms of the enzyme and cloning of type VI.

  1992cited by this paper
• Hormonal stimulation of adenylyl cyclase through Gi-protein beta gamma subunits.

  1992cited by this paper
• Stimulation of the type III olfactory adenylyl cyclase by calcium and calmodulin.

  1992cited by this paper
• Cloning and characterization of a sixth adenylyl cyclase isoform: types V and VI constitute a subgroup within the mammalian adenylyl cyclase family.

  1992cited by this paper
• Lowered responsiveness of the catalyst of adenylyl cyclase to stimulation by GS in heterologous desensitization: a role for adenosine 3',5'-monophosphate-dependent phosphorylation.

  1992cited by this paper
• Hormonal stimulation of adenylyl cyclase through Gi-protein βγ subunits

  1992cited by this paper
• Cloning and expression of a Ca(2+)-inhibitable adenylyl cyclase from NCB-20 cells.

  1992cited by this paper
• Cloning and expression of a widely distributed (type IV) adenylyl cyclase.

  1991cited by this paper
• Expression and characterization of calmodulin-activated (type I) adenylylcyclase.

  1991cited by this paper
• Inhibition of adenylate cyclase by Ca(2+)--a counterpart to stimulation by Ca2+/calmodulin.

  1991cited by this paper
• Type-specific regulation of adenylyl cyclase by G protein beta gamma subunits.

  1991cited by this paper
• Stoichiometry of receptor‐Gs‐adenylate cyclase interactions

  1991cited by this paper
• Identification of a specialized adenylyl cyclase that may mediate odorant detection.

  1990cited by this paper
• Adenylyl cyclase amino acid sequence: possible channel- or transporter-like structure.

  1989cited by this paper

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