Sensitization with Xenogeneic Tissues Alters the Heavy Chain Repertoire of Human Anti-Gal&agr;1–3Gal Antibodies

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Transplantation

• Publication date

  2005-07-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1097/01.TP.0000162976.07023.6DPMID 16003240
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Immunochemical Properties of Anti-Galα1–3Gal Antibodies After Sensitization with Xenogeneic Tissues

  2004cited by this paper
• Repertoire Shift in the Humoral Response to Phosphocholine-Keyhole Limpet Hemocyanin: VH Somatic Mutation in Germinal Center B Cells Impairs T15 Ig Function1

  2003cited by this paper
• Comparative analyses of immunoglobulin genes: surprises and portents

  2002cited by this paper
• Somatic immunoglobulin hypermutation.

  2002cited by this paper
• Gene Conversion-Like Sequence Transfers Between Transgenic Antibody V Genes Are Independent of RAD541

  2002cited by this paper
• The life and death of a B cell.

  2002cited by this paper
• Somatic Hypermutation Shapes the Antibody Repertoire of Memory B Cells in Humans

  2001cited by this paper
• BIOPHYSICAL CHARACTERISTICS OF ANTI-GAL&agr;1-3GAL IgM BINDING TO CELL SURFACES: IMPLICATIONS FOR XENOTRANSPLANTATION1

  2001cited by this paper
• The Structural Basis of Repertoire Shift in an Immune Response to Phosphocholine

  2000cited by this paper
• The human antibody response to porcine xenoantigens is encoded by IGHV3-11 and IGHV3-74 IgVH germline progenitors.

  1999cited by this paper
• Innate and acquired humoral immunities to influenza virus are mediated by distinct arms of the immune system.

  1999cited by this paper
• Naturally occurring anti-α-galactosyl antibodies: Relationship to xenoreactive anti-α-galactosyl antibodies

  1999cited by this paper
• Naturally occurring anti-alpha-galactosyl antibodies: relationship to xenoreactive anti-alpha-galactosyl antibodies.

  1999cited by this paper
• Linkages of innate and adaptive immunity.

  1998cited by this paper
• A Critical Role of Natural Immunoglobulin M in Immediate Defense Against Systemic Bacterial Infection

  1998cited by this paper
• Heterogeneity of human anti-pig natural antibodies cross-reactive with the Gal(alpha1,3)Galactose epitope.

  1997cited by this paper
• Analysis of the human VH gene repertoire. Differential effects of selection and somatic hypermutation on human peripheral CD5(+)/IgM+ and CD5(-)/IgM+ B cells.

  1997cited by this paper
• Specificity and Function of “Natural” Antibodies in Immunodeficient Subjects: Clues to B Cell Lineage and Development

  1997cited by this paper
• Cloning of anti-Gal Fabs from combinatorial phage display libraries: structural analysis and comparison of Fab expression in pComb3H and pComb8 phage.

  1997cited by this paper
• The Instructive Role of Innate Immunity in the Acquired Immune Response

  1996cited by this paper
• Avidity maturation, repertoire shift, and strain differences in antibodies to bacterial levan, a type 2 thymus-independent polysaccharide antigen.

  1996cited by this paper
• Anti‐Gal activity In diabetic patients transplanted with fetal porcine Islet cell clusters

  1995cited by this paper
• A novel mechanism of retrovirus inactivation in human serum mediated by anti-alpha-galactosyl natural antibody

  1995cited by this paper
• Human anti-Gal heavy chain genes. Preferential use of VH3 and the presence of somatic mutations.

  1995cited by this paper
• The V-region repertoire of Haemophilus influenzae type b polysaccharide antibodies induced by immunization of infants

  1995cited by this paper
• The human immunoglobulin VH repertoire.

  1995cited by this paper
• THE HUMORAL IMMUNE RESPONSE IN HUMANS FOLLOWING CROSS‐PERFUSION OF PORCINE ORGANS

  1995cited by this paper
• Human anti-Gal heavy chain genes

  1995cited by this paper
• Predominant V‐Region Gene Configurations in the Human Antibody Response to Haemophilus influenzae Capsule Polysaccharide

  1995cited by this paper
• MECHANISMS OF INJURY IN PORCINE LIVERS PERFUSED WITH BLOOD OF PATIENTS WITH FULMINANT HEPATIC FAILURE

  1994cited by this paper
• Brief report: treatment of hepatic failure with ex vivo pig-liver perfusion followed by liver transplantation.

  1994cited by this paper
• Clonotypic Dominance and Variable Gene Elements of Pathogenic Anti‐DNA Autoantibodies from a Single Patient with Lupus

  1994cited by this paper
• Characterization and affinity isolation of xenoreactive human natural antibodies.

  1994cited by this paper
• One percent of human circulating B lymphocytes are capable of producing the natural anti-Gal antibody.

  1993cited by this paper
• Interaction of the natural anti-Gal antibody with alpha-galactosyl epitopes: a major obstacle for xenotransplantation in humans.

  1993cited by this paper
• Anti-DNA antibodies secreted by peripheral B cells of lupus patients have both normal and lupus-specific features.

  1993cited by this paper
• Anti-pig IgM antibodies in human serum react predominantly with Gal(alpha 1-3)Gal epitopes.

  1993cited by this paper
• Identification of alpha-galactosyl and other carbohydrate epitopes that are bound by human anti-pig antibodies: relevance to discordant xenografting in man.

  1993cited by this paper
• The repertoire of human antibody to the Haemophilus influenzae type b capsular polysaccharide.

  1992cited by this paper
• NATURAL HUMAN IgG ANTIBODY WITH ANTI-β-GALACTOSYL SPECIFICITY

  1992cited by this paper
• Variable region diversity in human circulating antibodies specific for the capsular polysaccharide of Haemophilus influenzae type b. Preferential usage of two types of VH3 heavy chains.

  1991cited by this paper
• Natural autoantibodies: from 'horror autotoxicus' to 'gnothi seauton'.

  1991cited by this paper
• Structural characterization of the second major cross-reactive idiotype group of human rheumatoid factors. Association with the VH4 gene family.

  1990cited by this paper
• Structural characterization of human monoclonal cold agglutinins: Evidence for a distinct primary sequence‐defined VH4 idiotype

  1990cited by this paper
• Cold agglutinins: specificity, idiotypy and structural analysis.

  1990cited by this paper
• Immunogenic Gal alpha 1----3Gal carbohydrate epitopes are present on pathogenic American Trypanosoma and Leishmania.

  1989cited by this paper
• Idiotypic and subgroup analysis of human monoclonal rheumatoid factors. Implications for structural and genetic basis of autoantibodies in humans.

  1988cited by this paper
• Distinct patterns of heavy chain variable region subgroup use by human monoclonal autoantibodies of different specificity

  1988cited by this paper
• Evolutionary relationship between the natural anti-Gal antibody and the Gal alpha 1----3Gal epitope in primates.

  1987cited by this paper
• Evolutionary and somatic selection of the antibody repertoire in the mouse.

  1987cited by this paper
• Mutation Drift and Repertoire Shift in the Maturation of the Immune Response

  1987cited by this paper
• Diversity achieved by diverse mechanisms: gene conversion in developing B cells of the chicken.

  1987cited by this paper
• The natural anti-alpha-galactosyl IgG on human normal senescent red blood cells.

  1986cited by this paper
• The natural anti‐α‐galactosyl IgG on human normal senescent red blood cells

  1986cited by this paper
• Human natural anti-alpha-galactosyl IgG. II. The specific recognition of alpha (1----3)-linked galactose residues

  1985cited by this paper
• A unique natural human IgG antibody with anti-alpha-galactosyl specificity

  1984cited by this paper
• Natural antibodies and the immune response.

  1966cited by this paper
• SOME HISTOLOGICAL AND FUNCTIONAL ASPECTS OF LYMPHOID TISSUE IN GERMFREE ANIMALS: I. MORPHOLOGICAL STUDIES*

  1959cited by this paper
• ORIGIN OF ANTI-HUMAN BLOOD GROUP B AGGLUTININS IN WHITE LEGHORN CHICKS

  1959cited by this paper
• Origin of naturally occurring hemagglutinins and hemolysins; a review.

  1951cited by this paper
• THE PRECIPITIN REACTION BETWEEN TYPE III PNEUMOCOCCUS POLYSACCHARIDE AND HOMOLOGOUS ANTIBODY

  1935cited by this paper

• Xenotransplantation in transition.

  2022cites this paper
• The five dimensions of B cell tolerance

  2019cites this paper
• Anti-Gal in Humans and Its Antigen the α-Gal Epitope

  2018cites this paper
• Lessons from cardiac transplantation in infancy

  2009cites this paper
• Accommodation and antibodies.

  2009cites this paper
• Role of anti-MHC class I antibody in facilitating transplant accommodation.

  2008cites this paper
• Accommodation in organ transplantation

  2008cites this paper
• ccommodation of grafts : Implications for health nd disease

  2007cites this paper
• Accommodation of grafts: implications for health and disease.

  2007cites this paper