Experimental developments in movement disorders: update on proposed free radical mechanisms.

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Current Opinion in Neurology

• Publication date

  1998-08-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1097/00019052-199808000-00009PMID 9725079
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Animal Models of Action Tremor

  2008cited by this paper
• A novel neurological phenotype in mice lacking mitochondrial manganese superoxide dismutase

  1998cited by this paper
• Energy metabolism defects in Huntington's disease and effects of coenzyme Q10

  1997cited by this paper
• Effects of Wild‐Type and Mutated Copper/Zinc Superoxide Dismutase on Neuronal Survival and l‐DOPA‐Induced Toxicity in Postnatal Midbrain Culture

  1997cited by this paper
• Oxidative DNA Damage in the Parkinsonian Brain: An Apparent Selective Increase in 8‐Hydroxyguanine Levels in Substantia Nigra

  1997cited by this paper
• An immunohistochemical study on manganese superoxide dismutase in Parkinson's disease.

  1997cited by this paper
• Oxidative damage and metabolic dysfunction in Huntington's disease: Selective vulnerability of the basal ganglia

  1997cited by this paper
• A Generalised Increase in Protein Carbonyls in the Brain in Parkinson's but Not Incidental Lewy Body Disease

  1997cited by this paper
• Neuroprotective Effect of the Iron Chelator Desferrioxamine Against MPP+ Toxicity on Striatal Dopaminergic Terminals

  1997cited by this paper
• Midbrain dopaminergic neuronal degeneration in a transgenic mouse model of familial amyotrophic lateral sclerosis

  1997cited by this paper
• Generation of Reactive Oxygen Species by Tyrosine Hydroxylase: A Possible Contribution to the Degeneration of Dopaminergic Neurons?

  1997cited by this paper
• Elevated expression of glutathione peroxidase in PC12 cells results in protection against methamphetamine but not MPTP toxicity.

  1997cited by this paper
• Coenzyme Q10 levels correlate with the activities of complexes I and II/III in mitochondria from parkinsonian and nonparkinsonian subjects

  1997cited by this paper
• Involvement of iron in MPP+ toxicity in substantia nigra: protection by desferrioxamine.

  1997cited by this paper
• An Endogenous Dopaminergic Neurotoxin, N‐Methyl‐(R)‐Salsolinol, Induces DNA Damage in Human Dopaminergic Neuroblastoma SH‐SY5Y Cells

  1997cited by this paper
• Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice.

  1996cited by this paper
• Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury

  1996cited by this paper
• Dopamine-derived endogenous 1(R),2(N)-dimethyl-6,7-dihydroxy- 1,2,3,4-tetrahydroisoquinoline, N-methyl-(R)-salsolinol, induced parkinsonism in rat: biochemical, pathological and behavioral studies.

  1996cited by this paper
• Chronic 3-Nitropropionic Acid Treatment in Baboons Replicates the Cognitive and Motor Deficits of Huntington’s Disease

  1996cited by this paper
• Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease.

  1996cited by this paper
• Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly.

  1996cited by this paper
• Mitochondrial defect in Huntington's disease caudate nucleus

  1996cited by this paper
• Striatal Malonate Lesions Are Attenuated in Neuronal Nitric Oxide Synthase Knockout Mice

  1996cited by this paper
• Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity.

  1996cited by this paper
• Mice lacking extracellular superoxide dismutase are more sensitive to hyperoxia.

  1995cited by this paper
• Aging, energy, and oxidative stress in neurodegenerative diseases

  1995cited by this paper
• Superoxide dismutase in familial amyotrophic lateral sclerosis: models for gain of function.

  1995cited by this paper
• 3‐Nitropropionic Acid Neurotoxicity Is Attenuated in Copper/Zinc Superoxide Dismutase Transgenic Mice

  1995cited by this paper
• Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase

  1995cited by this paper
• Inhibition of Neuronal Nitric Oxide Synthase by 7‐Nitroindazole Protects Against MPTP‐Induced Neurotoxicity in Mice

  1995cited by this paper
• Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia

  1994cited by this paper
• Reduction of MPP(+)-induced hydroxyl radical formation and nigrostriatal MPTP toxicity by inhibiting nitric oxide synthase.

  1994cited by this paper
• Superoxide Dismutase Expression in Parkinson's Disease

  1994cited by this paper
• Chronic levodopa administration alters cerebral mitochondrial respiratory chain activity

  1993cited by this paper
• Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid

  1993cited by this paper
• Pharmacological characterization of PD 118717, a putative piperazinyl benzopyranone dopamine autoreceptor agonist.

  1992cited by this paper
• Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase.

  1992cited by this paper
• Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity

  1992cited by this paper
• The oxidant stress hypothesis in Parkinson's disease: Evidence supporting it

  1992cited by this paper
• Compensations after lesions of central dopaminergic neurons: some clinical and basic implications.

  1990cited by this paper
• A Selective Increase in Particulate Superoxide Dismutase Activity in Parkinsonian Substantia Nigra

  1989cited by this paper
• Basal Lipid Peroxidation in Substantia Nigra Is Increased in Parkinson's Disease

  1989cited by this paper
• Mitochondrial Complex I Deficiency in Parkinson's Disease

  1989cited by this paper
• Mitochondrial complex I deficiency in Parkinson's disease.

  1989cited by this paper
• Brain glutathione peroxidase in neurodegenerative disorders.

  1986cited by this paper
• Brain peroxidase and catalase in Parkinson disease.

  1975cited by this paper

• Assessment of Nutritional Value and Free Radical Scavenging Activity of Selected Genotypes of Cordia myxa L.

  2023cites this paper
• Assessment of Nutritional And Free Radical Scavenging Activity of Selected Genotypes of Cordia Myxa L.: A Potential Underutilized Fruit Crop of Indian Arid Zone

  2021cites this paper
• Lessons learned from protein aggregation: toward technological and biomedical applications

  2017cites this paper
• Chapter 40 – Etiology and Progression of Parkinson's Disease: Cross-Talk Between Environmental Factors and Genetic Vulnerability

  2017cites this paper
• Is the NMDA Receptor of the CA1 Region Participated in the Amnesic Effect of Harmane

  2016cites this paper
• The impact of 1MeTIQ on the dopaminergic system function in the 6-OHDA model of Parkinson’s disease

  2016cites this paper
• PRELIMINARY PHYTOCHEMICAL ANALYSIS AND IN VITRO ANTIOXIDANT ACTIVITY OF AQUA ALCOHOLIC EXTRACT OF SOLANUM NIGRUM LEAVES

  2015cites this paper
• FREE-RADICAL SCAVENGING ACTIVITY OF SOME FRESH AND REFRIGERATED FRUITS

  2015cites this paper
• ANTIBACTERIAL, ANTIOXIDANT AND PHYTOCHEMICAL SCREENING OF Hibiscus rosa sinensis, Acorus calamus, Cucurbita maxima and Moringa oliefera Thesis submitted to National Institute of Technology, Rourkela For the partial fulfilment of the Master degree in Life Science

  2012cites this paper
• Comfa Comsia and Molecular Docking Studies of AntioxidantChromone Derivatives

  2011cites this paper
• Parkinson's Disease: Cross-Talk Between Environmental Factors and Gene Defects

  2010cites this paper
• Caffeine Protects Against Disruptions of the Blood-Brain Barrier in Animal Models of Alzheimer's and Parkinson's Diseases

  2010cites this paper
• Antioxidant activities of Zizyphus mauritiana Lam. (Rhamnaceae)

  2009cites this paper
• The Mitochondrial ATP-Sensitive Potassium Channel Blocker 5-Hydroxydecanoate Inhibits Toxicity of 6-Hydroxydopamine on Dopaminergic Neurons

  2009cites this paper
• Animal Models of Parkinson's Disease to Aid Drug Discovery and Development

  2008cites this paper
• Caffeine protects against MPTP‐induced blood‐brain barrier dysfunction in mouse striatum

  2008cites this paper
• Untersuchung des Expressionsmusters und der Neuropathologie konditionaler Mausmodelle des Morbus Parkinson

  2008cites this paper
• Brain angiotensin enhances dopaminergic cell death via microglial activation and NADPH-derived ROS.

  2008cites this paper
• Angiotensin type-1-receptor antagonists reduce 6-hydroxydopamine toxicity for dopaminergic neurons.

  2007cites this paper
• Mechanism of 6‐hydroxydopamine neurotoxicity: the role of NADPH oxidase and microglial activation in 6‐hydroxydopamine‐induced degeneration of dopaminergic neurons

  2007cites this paper
• Age‐dependent telomere‐shortening is repressed by phosphorylated α‐tocopherol together with cellular longevity and intracellular oxidative‐stress reduction in human brain microvascular endotheliocytes

  2007cites this paper
• The Active Site Cysteine of the Proapoptotic Protein Glyceraldehyde-3-phosphate Dehydrogenase Is Essential in Oxidative Stress-induced Aggregation and Cell Death*

  2007cites this paper
• Reduction of dopaminergic degeneration and oxidative stress by inhibition of angiotensin converting enzyme in a MPTP model of parkinsonism.

  2006cites this paper
• Paeoniflorin attenuates neuroinflammation and dopaminergic neurodegeneration in the MPTP model of Parkinson's disease by activation of adenosine A1 receptor

  2006cites this paper
• Modulation of voltage‐gated channel currents by harmaline and harmane

  2005cites this paper
• Angiotensin‐converting enzyme inhibition reduces oxidative stress and protects dopaminergic neurons in a 6‐hydroxydopamine rat model of Parkinsonism

  2005cites this paper
• Neuronal expression of myeloperoxidase is increased in Alzheimer's disease

  2004cites this paper
• Comt inhibition in the treatment of Parkinson's disease: neuroprotection and future perspectives.

  2004cites this paper
• CNS diseases amenable to gene therapy.

  2003cites this paper
• Survival and differentiation of transplanted neural stem cells in mice brain with MPTP-induced Parkinson disease.

  2003cites this paper
• Gene Therapy for Neurological Diseases

  2003cites this paper
• Galectin-7 (PIG1) Exhibits Pro-apoptotic Function through JNK Activation and Mitochondrial Cytochrome cRelease* 210

  2002cites this paper
• Tyrosine 125 of α-synuclein plays a critical role for dimerization following nitrative stress

  2002cites this paper
• Tyrosine 125 of alpha-synuclein plays a critical role for dimerization following nitrative stress.

  2002cites this paper
• MPTP: a review of its mechanisms of neurotoxicity

  2001cites this paper
• Apoptosis, Glial Cells and Parkinson’s Disease

  2001cites this paper
• Mice transgenic for exon 1 of the Huntington's disease gene display reduced striatal sensitivity to neurotoxicity induced by dopamine and 6‐hydroxydopamine

  2001cites this paper
• Neuroprotective effects of D3 dopamine receptor agonists.

  2001cites this paper
• The last decade in Parkinson's disease research. Basic sciences.

  2001cites this paper
• Point Mutations in the α-Synuclein Gene.

  2001influential citation
• Neuronal Death by Accident or by Design

  2001cites this paper
• Tumor necrosis factor alpha is toxic to embryonic mesencephalic dopamine neurons.

  2001cites this paper
• Tumor Necrosis Factor α Is Toxic to Embryonic Mesencephalic Dopamine Neurons

  2001cites this paper
• Dityrosine Cross-linking Promotes Formation of Stable α-Synuclein Polymers

  2000cites this paper
• Advances in our Knowledge of MPTP Action and Mechanism

  2000cites this paper
• Time-course of Oxidation of Human Cerebrospinal Fluid Lipids in In Vitro

  2000cites this paper
• Time-course of oxidation of lipids in human cerebrospinal fluid in vitro

  2000cites this paper
• Dityrosine cross-linking promotes formation of stable alpha -synuclein polymers. Implication of nitrative and oxidative stress in the pathogenesis of neurodegenerative synucleinopathies.

  2000cites this paper
• The parkinsonian toxin MPTP: action and mechanism

  2000cites this paper
• Plasma Ubiquinol-10 as a Marker for Disease

  2000cites this paper
• Bioenergetics in Huntington's Disease

  1999cites this paper
• Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease

  1999cites this paper
• Polymorphonuclear leukocyte nitrite content and antioxidant enzymes in Parkinson's disease patients

  1999cites this paper
• Mass Spectrometric Quantification of 3-Nitrotyrosine, ortho-Tyrosine, and o,o′-Dityrosine in Brain Tissue of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated Mice, a Model of Oxidative Stress in Parkinson's Disease*

  1999cites this paper