A topoisomerase II-dependent G2 cycle checkpoint in mammalian cells

No abstract is available for this paper.

• Publication year

  1994

• Venue

  Nature

• Publication date

  1994-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/372467A0PMID 7984241
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Cell cycle progression and chromosome segregation in mammalian cells cultured in the presence of the topoisomerase II inhibitors ICRF-187 [(+)-1,2-bis(3,5-dioxopiperazinyl-1-yl)propane; ADR-529] and ICRF-159 (Razoxane).

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• Effect of ICRF-193, a novel DNA topoisomerase II inhibitor, on simian virus 40 DNA and chromosome replication in vitro

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• Sister chromatid separation in frog egg extracts requires DNA topoisomerase II activity during anaphase

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• The nucleoskeleton and the topology of replication.

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• Characteristics of an infinite life span diploid human fibroblast cell strain and a near-diploid strain arising from a clone of cells expressing a transfected v-myc oncogene.

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• Inhibitors of DNA topoisomerase II prevent chromatid separation in mammalian cells but do not prevent exit from mitosis.

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  1990cited by this paper
• Action of caffeine on DNA replication after ultraviolet irradiation in Indian muntjac cells: no connection with action on cell cycle delay.

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• Antitumour Activity in a Series of bisDiketopiperazines

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