Differential regulation of arginases and inducible nitric oxide synthase in murine macrophage cells.

No abstract is available for this paper.

• Publication year

  1998

• Venue

  American Journal of Physiology. Endocrinology and Metabolism

• Publication date

  1998-11-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1152/ajpendo.1998.275.5.E740PMID 29585228
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Distinct arginase isoforms expressed in primary and transformed macrophages: regulation by oxygen tension.

  1998influential reference
• Structure of the murine arginase II gene

  1998cited by this paper
• Nitric oxide and macrophage function.

  1997cited by this paper
• Involvement of protein kinase A in the induction of arginase in murine bone marrow-derived macrophages.

  1997cited by this paper
• Increasing cAMP Attenuates Induction of Inducible Nitric-oxide Synthase in Rat Primary Astrocytes*

  1997cited by this paper
• Human type II arginase: sequence analysis and tissue-specific expression.

  1997cited by this paper
• Regulation by cAMP of STAT1 activation in hepatic stellate cells.

  1997cited by this paper
• Differential regulation of macrophage arginine metabolism: a proposed role in wound healing.

  1997cited by this paper
• Chromosomal localization of the human arginase II gene and tissue distribution of its mRNA.

  1997cited by this paper
• An increase in intracellular cyclic AMP modulates nitric oxide production in IFN-gamma-treated macrophages.

  1997influential reference
• Coinduction of Nitric-oxide Synthase and Arginase I in Cultured Rat Peritoneal Macrophages and Rat Tissues in Vivo by Lipopolysaccharide*

  1997cited by this paper
• The Glucocorticoid-responsive Gene Cascade

  1997influential reference
• Novel actions of aspirin and sodium salicylate: discordant effects on nitric oxide synthesis and induction of nitric oxide synthase mRNA in a murine macrophage cell line

  1996cited by this paper
• Interleukin-1 beta-induced nitric oxide production from isolated rat islets is modulated by D-glucose and 3-isobutyl-1-methyl xanthine.

  1996cited by this paper
• Molecular cloning of cDNA for nonhepatic mitochondrial arginase (arginase II) and comparison of its induction with nitric oxide synthase in a murine macrophage‐like cell line

  1996influential reference
• Activation of Protein Kinase A Inhibits Interferon Induction of the Jak/Stat Pathway in U266 Cells (*)

  1996cited by this paper
• Comparative properties of arginases.

  1996cited by this paper
• Glucagon inhibits hepatocyte nitric oxide synthesis.

  1996cited by this paper
• Arginase activity in endothelial cells: inhibition by NG-hydroxy-L-arginine during high-output NO production.

  1996cited by this paper
• Inhibition of transcription factor Stat1 activity in mononuclear cell cultures and T cells by the cyclic AMP signaling pathway.

  1996cited by this paper
• Cloning and characterization of the human type II arginase gene.

  1996cited by this paper
• Lipocortin 1 mediates the inhibition by dexamethasone of the induction by endotoxin of nitric oxide synthase in the rat.

  1995cited by this paper
• Inhibition of arginase by in alveolar macrophages: implications for the utilization of l‐arginine for nitric oxide synthesis

  1995cited by this paper
• Co-induction of arginase and nitric oxide synthase in murine macrophages activated by lipopolysaccharide.

  1995influential reference
• Induction of nitric oxide synthase by cyclic AMP in rat vascular smooth muscle cells.

  1994cited by this paper
• New insights into the regulation of inducible nitric oxide synthesis.

  1994cited by this paper
• Role of interferon regulatory factor 1 in induction of nitric oxide synthase

  1994cited by this paper
• Inactivation of nitric oxide synthase after prolonged incubation of mouse macrophages with IFN-gamma and bacterial lipopolysaccharide.

  1994cited by this paper
• cAMP analogues and cholera toxin stimulate the accumulation of nitrite in rat peritoneal macrophage cultures.

  1994cited by this paper
• Two distinct signaling pathways trigger the expression of inducible nitric oxide synthase in rat renal mesangial cells.

  1994cited by this paper
• Mutagenesis of rat liver arginase expressed in Escherichia coli: role of conserved histidines.

  1994cited by this paper
• Tyrosine phosphorylated p91 binds to a single element in the ISGF2/IRF‐1 promoter to mediate induction by IFN alpha and IFN gamma, and is likely to autoregulate the p91 gene.

  1994cited by this paper
• Requirement for transcription factor IRF-1 in NO synthase induction in macrophages.

  1994cited by this paper
• Cyclic AMP-elevating agents induce an inducible type of nitric oxide synthase in cultured vascular smooth muscle cells. Synergism with the induction elicited by inflammatory cytokines.

  1993cited by this paper
• Norepinephrine Suppresses Inducible Nitric Oxide Synthase Activity in Rat Astroglial Cultures

  1993cited by this paper
• Complementation of a mutant cell line: central role of the 91 kDa polypeptide of ISGF3 in the interferon‐alpha and ‐gamma signal transduction pathways.

  1993cited by this paper
• Cloned and expressed macrophage nitric oxide synthase contrasts with the brain enzyme.

  1992cited by this paper
• Purification and cloning of interferon-stimulated gene factor 2 (ISGF2): ISGF2 (IRF-1) can bind to the promoters of both beta interferon- and interferon-stimulated genes but is not a primary transcriptional activator of either

  1990cited by this paper
• Tumor necrosis factor-induced activation of peritoneal macrophages is regulated by prostaglandin E2 and cAMP.

  1988cited by this paper
• Regulation of messenger ribonucleic acid levels for five urea cycle enzymes in cultured rat hepatocytes. Requirements for cyclic adenosine monophosphate, glucocorticoids, and ongoing protein synthesis.

  1988influential reference
• Rapid expression of ornithine decarboxylase mRNA in a macrophage‐like cell line: cAMP repression of the requirement for prior protein synthesis

  1988cited by this paper
• Multiple molecular forms of mouse liver arginase.

  1988cited by this paper
• Arginine metabolism in wounds.

  1988cited by this paper
• Regulation of mRNA levels for five urea cycle enzymes in rat liver by diet, cyclic AMP, and glucocorticoids.

  1987cited by this paper
• Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction.

  1987cited by this paper
• Complete nucleotide sequence of cDNA and deduced amino acid sequence of rat liver arginase.

  1987cited by this paper
• Cloning of rat liver arginase cDNA and elucidation of regulation of arginase gene expression in H4 rat hepatoma cells

  1986cited by this paper
• Studies on the methylation of avian sarcoma proviruses in permissive and non-permissive cells.

  1983cited by this paper
• Regulation of glucocorticoids of arginase and argininosuccinate synthetase in cultured rat hepatoma cells.

  1982cited by this paper
• Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids.

  1982cited by this paper
• Serum factors required for arginase induction in macrophages.

  1980cited by this paper
• Arginase production by peritoneal macrophages: a new assay.

  1980cited by this paper
• Properties of fetal and adult red blood cell arginase: a possible prenatal diagnostic test for arginase deficiency.

  1980cited by this paper
• Induction of ornithine decarboxylase in macrophages by bacterial lipopolysaccharides (LPS) and mycobacterial cell wall material.

  1980cited by this paper

• Discovery of Marine-Inspired Guanidine-Based PDE4 Inhibitors for the Treatment of Chronic Obstructive Pulmonary Disease

  2026cites this paper
• Equine monocyte-derived macrophages revisited: isolation and comprehensive characterization of pro- versus anti-inflammatory polarisation

  2025cites this paper
• The roles of arginases and arginine in immunity

  2024cites this paper
• Triamcinolone Acetonide Protects Against Light-Induced Retinal Degeneration by Activating Anti-Inflammatory STAT6/Arg1 Signaling in Microglia

  2024cites this paper
• Neither injury induced macrophages within the nerve, nor the environment created by Wallerian degeneration is necessary for enhanced in vivo axon regeneration after peripheral nerve injury

  2024cites this paper
• Xiao-Chai-Hu Decoction Ameliorates Poly (I:C)-Induced Viral Pneumonia through Inhibiting Inflammatory Response and Modulating Serum Metabolism

  2022cites this paper
• The Dark Side of an Essential Amino Acid: L-Arginine in Spinal Cord Injury

  2022cites this paper
• CD14 regulates the metabolomic profiles of distinct macrophage subsets under steady and activated states.

  2022cites this paper
• Arginase Activity in Eisenia andrei Coelomocytes: Function in the Earthworm Innate Response

  2021cites this paper
• Arginase II protein regulates Parkin-dependent p32 degradation that contributes to Ca2+-dependent eNOS activation in endothelial cells

  2021cites this paper
• Механизмы нарушения метаболизма L-аргинина в эндотелиальных клетках

  2021cites this paper
• The Mechanisms of L-Arginine Metabolism Disorder in Endothelial Cells

  2021cites this paper
• Arginase Gene Polymorphism Increases Risk of Diabetic Retinopathy in Type 2 Diabetes Mellitus Patients

  2021cites this paper
• Arginine-dependent immune responses

  2021cites this paper
• PHASE 2 RANDOMIZED CONTROL TRIAL OF ARGININE THERAPY FOR PEDIATRIC SICKLE CELL DISEASE PAIN

  2020cites this paper
• Toll-Like Receptor 2-Tpl2-Dependent ERK Signaling Drives Inverse Interleukin 12 Regulation in Dendritic Cells and Macrophages

  2020influential citation
• Dietary arginine and citrulline supplementation modulates the immune condition and inflammatory response of European seabass.

  2020cites this paper
• Microglial polarization in posttraumatic epilepsy: Potential mechanism and treatment opportunity

  2020cites this paper
• p32-Dependent p38 MAPK Activation by Arginase II Downregulation Contributes to Endothelial Nitric Oxide Synthase Activation in HUVECs

  2020cites this paper
• Selective inhibition of arginase-2 in endothelial cells but not proximal tubules reduces renal fibrosis

  2020cites this paper
• The Arginase Pathway in Neonatal Brain Hypoxia-Ischemia

  2019cites this paper
• Bench to bedside review: therapeutic modulation of nitric oxide in sepsis—an update

  2019cites this paper
• Arginase II activity regulates cytosolic Ca2+ level in a p32-dependent manner that contributes to Ca2+-dependent vasoconstriction in native low-density lipoprotein-stimulated vascular smooth muscle cells

  2019cites this paper
• Relevance of Erk1/2-PI3K/Akt signaling pathway in CEES-induced oxidative stress regulates inflammation and apoptosis in keratinocytes

  2019cites this paper
• Toll-like receptor 4/nuclear factor-kappa B pathway is involved in activating microphages by polysaccharides isolated from Fagopyrum esculentum

  2019cites this paper
• Arginase II Contributes to the Ca2+/CaMKII/eNOS Axis by Regulating Ca2+ Concentration Between the Cytosol and Mitochondria in a p32‐Dependent Manner

  2018cites this paper
• Host-Derived Nitric Oxide and Its Antibacterial Effects in the Urinary Tract.

  2018cites this paper
• Src promotes anti‐inflammatory (M2) macrophage generation via the IL‐4/STAT6 pathway

  2018cites this paper
• Cytosolic DNA Sensing Promotes Macrophage Transformation and Governs Myocardial Ischemic Injury

  2018cites this paper
• Blockade of Interleukin-7 Receptor Shapes Macrophage Alternative Activation and Promotes Functional Recovery After Spinal Cord Injury.

  2017cites this paper
• Acquired Amino Acid Deficiencies: A Focus on Arginine and Glutamine

  2017cites this paper
• Arginase-2 mediates renal ischemia-reperfusion injury.

  2017cites this paper
• l-Arginine and TNFα Production in Macrophages: A Focus on Metabolism, Aging, Metabolic Syndrome, and Type 2 Diabetes

  2017cites this paper
• Arginine metabolic endotypes related to asthma severity

  2017cites this paper
• Liposome‐induced immunosuppression and tumor growth is mediated by macrophages and mitigated by liposome‐encapsulated alendronate☆

  2017cites this paper
• The untold story of IFN-γ in cancer biology.

  2016cites this paper
• Antiretrovirals inhibit arginase in human microglia

  2016cites this paper
• Review of Triple Negative Breast Cancer and the Impact of Inducible Nitric Oxide Synthase on Tumor Biology and Patient Outcomes.

  2016cites this paper
• Strategies to Enhance the Therapeutic Ratio of Radiation as a Cancer Treatment

  2016cites this paper
• infection and stress Candida albicans Immunocompetence of macrophages in rats exposed to

  2016cites this paper
• Novel Strategies to Prevent, Mitigate or Reverse Radiation Injury and Fibrosis

  2016cites this paper
• CUNY Academic

  2016cites this paper
• Natural product derivative BIO promotes recovery after myocardial infarction via unique modulation of the cardiac microenvironment

  2016cites this paper
• Parallel Expression of Enzyme Inhibitors of CD8T Cell Activity in Tumor Microenvironments and Secretory Endometrium

  2016cites this paper
• Immunomodulation of Macrophages in Periapical Wound Healing

  2016cites this paper
• Macrophage Ablation Reduces M2-Like Populations and Jeopardizes Tumor Growth in a MAFIA-Based Glioma Model

  2015cites this paper
• Amino acid metabolism in the inflammatory niche

  2015cites this paper
• Interferon-Gamma and Nitric Oxide Synthase 2 Mediate the Aggregation of Resident Adherent Peritoneal Exudate Cells: Implications for the Host Response to Pathogens

  2015cites this paper
• A Novel Arginase Inhibitor Derived from Scutellavia indica Restored Endothelial Function in ApoE-Null Mice Fed a High-Cholesterol Diet

  2015cites this paper
• Mechanisms of Nitric Oxide-Dependent Regulation of Tumor Invasion and Metastasis

  2015cites this paper
• Serotonin & developmental axonal refinement : microglia contribution ?

  2015cites this paper
• Mechanisms of 2,4-Dinitrochlorobenzene-induced acute inflammation in Human Papillomavirus type 16 E7 oncoprotein expressing skin

  2015cites this paper
• Arginine and Citrulline and the Immune Response in Sepsis

  2015cites this paper
• postinsult immune paralysis Decreased exhaled nitric oxide as a marker of

  2015cites this paper
• TIPE2 Negatively Regulates Inflammation by Switching Arginine Metabolism from Nitric Oxide Synthase to Arginase

  2014cites this paper
• Retrograde Translocation of Arginase 2 in Aortic Endothelial Cells via ROCK and Mitochondrial Processing Peptidase

  2014cites this paper
• OxLDL Triggers Retrograde Translocation of Arginase2 in Aortic Endothelial Cells via ROCK and Mitochondrial Processing Peptidase

  2014cites this paper
• The Central Role of Arginine Catabolism in T-Cell Dysfunction and Increased Susceptibility to Infection After Physical Injury

  2014cites this paper
• Asymmetric dimethylarginine does not inhibit arginase activity and is pro‐proliferative in pulmonary endothelial cells

  2014influential citation
• Tumor-Induced Immune Suppression

  2014cites this paper
• Characterization of arginase expression by equine neutrophils.

  2014cites this paper
• Imogolite: an aluminosilicate nanotube endowed with low cytotoxicity and genotoxicity.

  2014cites this paper
• Arginine-based polyester amide/polysaccharide hydrogels and their biological response.

  2014cites this paper
• Common and small molecules as the ultimate regulatory and effector mediators of antigen-specific transplantation reactions.

  2013cites this paper
• Synthesis, Characteriaztion Of Chitosan-Based Derivatives, Their Hydrogels And Hybrids, And A New Family Of Arginine Based Polyester Urea Urethane

  2013cites this paper
• Effects of acute‐liver‐failure‐plasma exposure on hepatic functionality of HepaRG‐AMC‐Bioartificial Liver

  2013cites this paper
• Insights into the arginine paradox: evidence against the importance of subcellular location of arginase and eNOS.

  2013cites this paper
• Arginase II inhibited lipopolysaccharide-induced cell death by regulation of iNOS and Bcl-2 family proteins in macrophages

  2013cites this paper
• The Protective Effect of PNU-282987, a Selective &agr;7 Nicotinic Acetylcholine Receptor Agonist, on the Hepatic Ischemia-Reperfusion Injury Is Associated With the Inhibition of High-Mobility Group Box 1 Protein Expression and Nuclear Factor &kgr;B Activation in Mice

  2013cites this paper
• Contribution of arginase activation to vascular dysfunction in cigarette smoking.

  2013cites this paper
• An Integrative Framework for Bayesian Variable Selection with Informative Priors for Identifying Genes and Pathways

  2013cites this paper
• Development of Novel Arginase Inhibitors for Therapy of Endothelial Dysfunction

  2013cites this paper
• Liposomal Targeting of Prednisolone Phosphate to Synovial Lining Macrophages during Experimental Arthritis Inhibits M1 Activation but Does Not Favor M2 Differentiation

  2013influential citation
• Arginine metabolism profile in infection: Application in pathogenesis infections

  2013cites this paper
• Crosstalk of human mesenchymal stromal cells with the cellular components of the immune system

  2013cites this paper
• Increased sensitivity to ozone-induced injury and altered pulmonary mechanics in mice with chronic lung inflammation. effects of aging

  2013cites this paper
• The role of syndecan-1 in the resolution of chronic inflammatory responses

  2013cites this paper
• Arginase inhibition mediates renal tissue protection in diabetic nephropathy by a nitric oxide synthase 3-dependent mechanism

  2013cites this paper
• Arginase inhibition reduces interleukin-1β-stimulated vascular smooth muscle cell proliferation by increasing nitric oxide synthase-dependent nitric oxide production.

  2013cites this paper
• Pharmacologic agents elevating cAMP prevent arginase II expression and proliferation of pulmonary artery smooth muscle cells.

  2012cites this paper
• Macrophage Plasticity and Polarization: Cell Signaling Mechanisms and Roles in Immunity

  2012cites this paper
• UvA-DARE ( Digital Academic Repository ) Human liver cell lines for the AMC-bioartificial liver

  2012cites this paper
• Pollutant Particles Induce Arginase II in Human Bronchial Epithelial Cells

  2012cites this paper
• Effects of acute-liver-failure-plasma exposure on hepatic functionality of HepaRG-AMC-Bioartificial Liver

  2012cites this paper
• Upregulation of arginase-II contributes to decreased age-related myocardial contractile reserve

  2012cites this paper
• Human liver cell lines for the AMC-bioartificial liver

  2012cites this paper
• A new metabolomic assay to examine inflammation and redox pathways following LPS challenge

  2012influential citation
• Arginase II Promotes Macrophage Inflammatory Responses Through Mitochondrial Reactive Oxygen Species, Contributing to Insulin Resistance and Atherogenesis

  2012cites this paper
• Human liver cell lines for the AMC-bioartificial liver

  2012cites this paper
• Nitric oxide and related enzymes in asthma: relation to severity, enzyme function and inflammation

  2012cites this paper
• Increased arginase II activity contributes to endothelial dysfunction through endothelial nitric oxide synthase uncoupling in aged mice

  2012cites this paper
• Selective Endothelial Overexpression of Arginase II Induces Endothelial Dysfunction and Hypertension and Enhances Atherosclerosis in Mice

  2012cites this paper
• The Construction of a Plasmid for Detecting the Pathway of Arginine Metabolism in Human Macrophages: a Real-Time Assessment of Macrophage Polarity

  2012cites this paper
• Progressive Visceral Leishmaniasis Is Driven by Dominant Parasite-induced STAT6 Activation and STAT6-dependent Host Arginase 1 Expression

  2012cites this paper
• NOS‐2 signaling and cancer therapy

  2012cites this paper
• The Effect of Rat Acute-Liver-Failure Plasma on HepaRG Cells

  2012cites this paper
• Endothelial arginase II and atherosclerosis

  2011cites this paper
• Effect of azithromycin on macrophage phenotype during pulmonary infections and cystic fibrosis

  2011cites this paper
• Aging alters the production of iNOS, arginase and cytokines in murine macrophages.

  2011cites this paper
• OxLDL-dependent activation of arginase II is dependent on the LOX-1 receptor and downstream RhoA signaling.

  2011cites this paper