The Leptin Receptor*

No abstract is available for this paper.

• Publication year

  1997

• Venue

  Journal of Biological Chemistry

• Publication date

  1997-03-07

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1074/jbc.272.10.6093PMID 9102398
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Leptin Receptor (OB-R) Signaling

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• Role of leptin in fat regulation

  1996cited by this paper
• Endotoxin and cytokines induce expression of leptin, the ob gene product, in hamsters.

  1996cited by this paper
• Phenotype of fatty Due to Gln269Pro Mutation in the Leptin Receptor (Lepr)

  1996cited by this paper
• Abnormal splicing of the leptin receptor in diabetic mice

  1996cited by this paper
• Cerebrospinal fluid leptin levels: Relationship to plasma levels and to adiposity in humans

  1996cited by this paper
• Leptin receptor missense mutation in the fatty Zucker rat

  1996cited by this paper
• Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice.

  1996cited by this paper
• Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease.

  1996cited by this paper
• Indication for Linkage of the Human OB Gene Region With Extreme Obesity

  1996cited by this paper
• Absence of Mutations in the Human OB Gene in Obese/Diabetic Subjects

  1996cited by this paper
• Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway.

  1996cited by this paper
• Decreased cerebrospinal-fluid/serum leptin ratio in obesity: a possible mechanism for leptin resistance.

  1996cited by this paper
• Obese gene expression: reduction by fasting and stimulation by insulin and glucose in lean mice, and persistent elevation in acquired (diet-induced) and genetic (yellow agouti) obesity.

  1996cited by this paper
• Defective STAT signaling by the leptin receptor in diabetic mice.

  1996cited by this paper
• Serum immunoreactive-leptin concentrations in normal-weight and obese humans.

  1996cited by this paper
• Stat6 is required for mediating responses to IL-4 and for development of Th2 cells.

  1996cited by this paper
• OB protein binds specifically to the choroid plexus of mice and rats.

  1996cited by this paper
• Leptin activation of Stat3 in the hypothalamus of wild–type and ob/ob mice but not db/db mice

  1996cited by this paper
• The hypothalamic leptin receptor in humans: identification of incidental sequence polymorphisms and absence of the db/db mouse and fa/fa rat mutations.

  1996cited by this paper
• Nonsense mutation of leptin receptor in the obese spontaneously hypertensive Koletsky rat

  1996cited by this paper
• Regulation of Expression of ob mRNA and Protein by Glucocorticoids and cAMP (*)

  1996cited by this paper
• Extreme Obesity May Be Linked to Markers Flanking the Human OB Gene

  1996cited by this paper
• Phenotypes of Mouse diabetes and Rat fatty Due to Mutations in the OB (Leptin) Receptor

  1996cited by this paper
• Novel B219/OB receptor isoforms: Possible role of leptin in hematopoiesis and reproduction

  1996cited by this paper
• Human Obese Gene: Molecular Screening in Japanese and Asian Indian NIDDM Patients Associated With Obesity

  1996cited by this paper
• Leptin enters the brain by a saturable system independent of insulin.

  1996cited by this paper
• Localization of leptin receptor mRNA and the long form splice variant (Ob‐Rb) in mouse hypothalamus and adjacent brain regions by in situ hybridization

  1996cited by this paper
• The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors.

  1996cited by this paper
• Identification of targets of leptin action in rat hypothalamus.

  1996cited by this paper
• Identification of Incidental Sequence Polymorphisms and Absence of the db/db Mouse and fa/fa Rat Mutations

  1996cited by this paper
• Role of leptin in the neuroendocrine response to fasting

  1996cited by this paper
• Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted State6 gene

  1996cited by this paper
• Essential role of Stat6 in IL-4 signalling

  1996cited by this paper
• Leptin levels reflect body lipid content in mice: Evidence for diet-induced resistance to leptin action

  1995cited by this paper
• Increased obese mRNA expression in omental fat cells from massively obese humans

  1995cited by this paper
• Weight-reducing effects of the plasma protein encoded by the obese gene.

  1995cited by this paper
• Overexpression of the obese (ob) gene in adipose tissue of human obese subjects

  1995cited by this paper
• The role of neuropeptide Y in the antiobesity action of the obese gene product

  1995cited by this paper
• Identification and expression cloning of a leptin receptor, OB-R.

  1995cited by this paper
• Dimerization of cell surface receptors in signal transduction.

  1995cited by this paper
• Evidence against either a premature stop codon or the absence of obese gene mRNA in human obesity.

  1995cited by this paper
• Threading analysis suggests that the obese gene product may be a helical cytokine

  1995cited by this paper
• Expression of ob mRNA and its encoded protein in rodents. Impact of nutrition and obesity.

  1995cited by this paper
• Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects

  1995cited by this paper
• Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks.

  1995cited by this paper
• Increased expression in adipocytes of ob RNA in mice with lesions of the hypothalamus and with mutations at the db locus.

  1995cited by this paper
• Effects of the obese gene product on body weight regulation in ob/ob mice.

  1995cited by this paper
• Transient increase in obese gene expression after food intake or insulin administration

  1995cited by this paper
• Cytokine signal transduction.

  1994cited by this paper
• The insulin signaling system.

  1994cited by this paper
• Positional cloning of the mouse obese gene and its human homologue

  1994cited by this paper
• Leukemia inhibitory factor receptor is structurally related to the IL‐6 signal transducer, gp130.

  1991cited by this paper
• Rat obesity gene fatty (fa) maps to chromosome 5: evidence for homology with the mouse gene diabetes (db).

  1991cited by this paper
• Expression cloning of a human granulocyte colony-stimulating factor receptor: a structural mosaic of hematopoietin receptor, immunoglobulin, and fibronectin domains

  1990cited by this paper
• Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130.

  1989cited by this paper
• Obese and diabetes: Two mutant genes causing diabetes-obesity syndromes in mice

  1978cited by this paper
• Effects of parabiosis of obese with diabetes and normal mice

  1973cited by this paper
• Diabetes, a New Mutafton in the Mouse

  1966cited by this paper
• Obese, a new mutation in the house mouse.

  1950cited by this paper
• Obese, a new mutation in the house mouse.

  1950cited by this paper

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