Functional and genomic analyses of blocked protein O‐mannosylation in baker's yeast

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Molecular Microbiology

• Publication date

  2011-03-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1111/j.1365-2958.2011.07537.xPMID 21231968
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Protein O-mannosylation: conserved from bacteria to humans.

  2009influential reference
• Glycosylation defects activate filamentous growth Kss1 MAPK and inhibit osmoregulatory Hog1 MAPK

  2009cited by this paper
• The unfolded protein response is induced by the cell wall integrity mitogen-activated protein kinase signaling cascade and is required for cell wall integrity in Saccharomyces cerevisiae.

  2009cited by this paper
• ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

  2009cited by this paper
• O‐Mannosylation is required for the solubilization of heterologously expressed human β‐amyloid precursor protein in Saccharomyces cerevisiae

  2009cited by this paper
• The cell wall and endoplasmic reticulum stress responses are coordinately regulated in Saccharomyces cerevisiae

  2009cited by this paper
• POMT1 and POMT2 mutations in CMD patients: a multicentric Italian study.

  2008cited by this paper
• Hos2p/Set3p Deacetylase Complex Signals Secretory Stress through the Mpk1p Cell Integrity Pathway

  2008cited by this paper
• Transcriptional and physiological adaptation to defective protein‐O‐mannosylation in Candida albicans

  2007influential reference
• Signal integration in the endoplasmic reticulum unfolded protein response

  2007influential reference
• Function and regulation in MAPK signaling pathways: lessons learned from the yeast Saccharomyces cerevisiae.

  2007cited by this paper
• GENECODIS: a web-based tool for finding significant concurrent annotations in gene lists

  2007cited by this paper
• The sequential activation of the yeast HOG and SLT2 pathways is required for cell survival to cell wall stress.

  2007cited by this paper
• O-mannosylation is required for degradation of the endoplasmic reticulum-associated degradation substrate Gas1*p via the ubiquitin/proteasome pathway in Saccharomyces cerevisiae.

  2007influential reference
• Membrane association is a determinant for substrate recognition by PMT4 protein O-mannosyltransferases

  2007influential reference
• Regulation of Mating and Filamentation Genes by Two Distinct Ste12 Complexes in Saccharomyces cerevisiae

  2006cited by this paper
• Pheromone Signaling Pathways in Yeast

  2006cited by this paper
• Genome-wide analysis of the response to protein glycosylation deficiency in yeast.

  2006cited by this paper
• Protein glycosylation, conserved from yeast to man: a model organism helps elucidate congenital human diseases.

  2006influential reference
• Cell wall construction in Saccharomyces cerevisiae

  2006influential reference
• Genome‐wide analysis of the unfolded protein response in fibroblasts from congenital disorders of glycosylation type‐I patients

  2005cited by this paper
• Identification of Mitogen-Activated Protein Kinase Signaling Pathways That Confer Resistance to Endoplasmic Reticulum Stress in Saccharomyces cerevisiae

  2005influential reference
• Cell Wall Integrity Signaling in Saccharomyces cerevisiae

  2005cited by this paper
• Roles of O-Mannosylation of Aberrant Proteins in Reduction of the Load for Endoplasmic Reticulum Chaperones in Yeast*

  2004cited by this paper
• Chromatin Immunoprecipitation for Determining the Association of Proteins with Specific Genomic Sequences In Vivo

  2004cited by this paper
• Roles of N-linked glycans in the endoplasmic reticulum.

  2004cited by this paper
• Aberrant Processing of the WSC Family and Mid2p Cell Surface Sensors Results in Cell Death of Saccharomyces cerevisiae O-Mannosylation Mutants

  2004cited by this paper
• Rhodanine-3-acetic acid derivatives as inhibitors of fungal protein mannosyl transferase 1 (PMT1).

  2004influential reference
• Principles of MAP kinase signaling specificity in Saccharomyces cerevisiae.

  2004cited by this paper
• The Global Transcriptional Response to Transient Cell Wall Damage in Saccharomyces cerevisiae and Its Regulation by the Cell Integrity Signaling Pathway*

  2004influential reference
• Functional Mapping of Quantitative Trait Loci Underlying Growth Trajectories Using a Transform‐Both‐Sides Logistic Model

  2004influential reference
• Chromatin Immunoprecipitation for Determining the Association of Proteins with Specific Genomic Sequences In Vivo

  2004cited by this paper
• Genome-wide Analysis of the Response to Cell Wall Mutations in the Yeast Saccharomyces cerevisiae*

  2003influential reference
• Members of the Evolutionarily Conserved PMT Family of ProteinO-Mannosyltransferases Form Distinct Protein Complexes among Themselves*

  2003influential reference
• Program-specific distribution of a transcription factor dependent on partner transcription factor and MAPK signaling.

  2003cited by this paper
• TM4: a free, open-source system for microarray data management and analysis.

  2003cited by this paper
• Unique and redundant roles for HOG MAPK pathway components as revealed by whole-genome expression analysis.

  2003cited by this paper
• O-mannosyl glycans: from yeast to novel associations with human disease.

  2003cited by this paper
• A comprehensive analysis of gene expression profiles in a yeast N-glycosylation mutant.

  2001influential reference
• O-mannosylation protects mutant alpha-factor precursor from endoplasmic reticulum-associated degradation.

  2001cited by this paper
• A Bayesian framework for the analysis of microarray expression data: regularized t -test and statistical inferences of gene changes

  2001cited by this paper
• Functional discovery via a compendium of expression profiles.

  2000cited by this paper
• The unfolded protein response represses nitrogen-starvation induced developmental differentiation in yeast.

  2000cited by this paper
• Structure-Function Analysis of the Dolichyl Phosphate-Mannose: Protein O-Mannosyltransferase ScPmt1p*

  2000cited by this paper
• Signaling and circuitry of multiple MAPK pathways revealed by a matrix of global gene expression profiles.

  2000cited by this paper
• Defects in protein glycosylation cause SHO1-dependent activation of a STE12 signaling pathway in yeast.

  2000influential reference
• Functional and Genomic Analyses Reveal an Essential Coordination between the Unfolded Protein Response and ER-Associated Degradation

  2000influential reference
• Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation.

  2000cited by this paper
• Protein O-mannosylation.

  1999cited by this paper
• The contribution of the O‐glycosylated protein Pir2p/Hsp150 to the construction of the yeast cell wall in wild‐type cells and β1,6‐glucan‐deficient mutants

  1999cited by this paper
• Mnt2p and Mnt3p of Saccharomyces cerevisiae are members of the Mnn1p family of alpha-1,3-mannosyltransferases responsible for adding the terminal mannose residues of O-linked oligosaccharides.

  1999cited by this paper
• The MAPKKK Ste11 regulates vegetative growth through a kinase cascade of shared signaling components.

  1999cited by this paper
• Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls.

  1999influential reference
• Mapping DNA interaction sites of chromosomal proteins. Crosslinking studies in yeast.

  1999cited by this paper
• O-Glycosylation of Axl2/Bud10p by Pmt4p Is Required for Its Stability, Localization, and Function in Daughter Cells

  1999cited by this paper
• Genome‐wide analysis of gene expression regulated by the yeast cell wall integrity signalling pathway

  1999cited by this paper
• The KTR and MNN1 mannosyltransferase families of Saccharomyces cerevisiae.

  1999cited by this paper
• Mapping DNA Interaction Sites of Chromosomal Proteins

  1999cited by this paper
• The control of filamentous differentiation and virulence in fungi.

  1998influential reference
• Endoplasmic Reticulum Degradation of a Mutated ATP-binding Cassette Transporter Pdr5 Proceeds in a Concerted Action of Sec61 and the Proteasome*

  1998cited by this paper
• Concepts and principles of O-linked glycosylation.

  1998cited by this paper
• Protein-O-glycosylation in yeast: protein-specific mannosyltransferases.

  1997cited by this paper
• Yeast pseudohyphal growth is regulated by GPA2, a G protein α homolog

  1997cited by this paper
• Yeast pseudohyphal growth is regulated by GPA2, a G protein alpha homolog.

  1997cited by this paper
• Heterologous HIS3 Marker and GFP Reporter Modules for PCR‐Targeting in Saccharomyces cerevisiae

  1997cited by this paper
• Muc1, a mucin-like protein that is regulated by Mss10, is critical for pseudohyphal differentiation in yeast.

  1996cited by this paper
• The PMT gene family: protein O‐glycosylation in Saccharomyces cerevisiae is vital.

  1996influential reference
• Saccharomyces cerevisiae TEC1 is required for pseudohyphal growth

  1996cited by this paper
• PMT1, the gene for a key enzyme of protein O-glycosylation in Saccharomyces cerevisiae.

  1993influential reference
• Improved method for high efficiency transformation of intact yeast cells.

  1992cited by this paper
• Growth and Manipulation of Yeast

  1992cited by this paper
• OCH1 encodes a novel membrane bound mannosyltransferase: outer chain elongation of asparagine‐linked oligosaccharides.

  1992cited by this paper
• Growth and Manipulation of Yeast

  1992cited by this paper
• Properties of the DNA-binding domain of the Saccharomyces cerevisiae STE12 protein

  1991cited by this paper
• Vanadate-resistant yeast mutants are defective in protein glycosylation.

  1991cited by this paper
• Yeast/E. coli shuttle vectors with multiple unique restriction sites

  1986cited by this paper

• The Schizosaccharomyces pombe Glycosyltransferase Gmh5 is a Functional Homologue of the α-1,6-Mannosyltransferase Mnn10 Crucial for N-Glycan Processing

  2025cites this paper
• mRNA decapping activator Pat1 is required for efficient yeast adaptive transcriptional responses via the Cell Wall Integrity MAPK pathway.

  2024cites this paper
• The role of manganese in morphogenesis and pathogenesis of the opportunistic fungal pathogen Candida albicans

  2023cites this paper
• Development of a novel target-based cell assay, reporter of the activity of mycobacterium tuberculosis protein-O-mannosyltransferase.

  2023cites this paper
• Protein O-mannosylation across kingdoms and related diseases: From glycobiology to glycopathology.

  2022cites this paper
• Fungal cell wall: An underexploited target for antifungal therapies

  2021cites this paper
• The Saccharomyces cerevisiae Ncw2 protein works on the chitin/β-glucan organisation of the cell wall

  2021cites this paper
• Our pursuit for effective antifungal agents targeting fungal cell wall components, where are we?

  2021cites this paper
• Overview of yeast environmental stress response pathways and the development of tolerant yeasts

  2021cites this paper
• Cell Wall Strengthening and Remodeling Provide New Insights on Sclerotia Development of Medicinal Fungus Polyporus Umbellatus

  2020cites this paper
• The Degree and Length of O‐Glycosylation of Recombinant Proteins Produced in Pichia pastoris Depends on the Nature of the Protein and the Process Type

  2020cites this paper
• Functional implications of MIR domains in protein O-mannosylation

  2020cites this paper
• Translational Regulation of Pmt1 and Pmt2 by Bfr1 Affects Unfolded Protein O-Mannosylation

  2019cites this paper
• Translation Control of HAC1 by Regulation of Splicing in Saccharomyces cerevisiae

  2019cites this paper
• Vph2 is required for protection against a reductive stress in Candida albicans.

  2019cites this paper
• Rational strain engineering interventions to enhance cellulase secretion by Saccharomyces cerevisiae

  2018cites this paper
• Monitoring Protein Dynamics in Protein O-Mannosyltransferase Mutants In Vivo by Tandem Fluorescent Protein Timers

  2018cites this paper
• Engineering of Yeast Glycoprotein Expression.

  2018cites this paper
• PMT1 deficiency extends the shortened replicative lifespan of TED1-deficient yeast in a Hac1p-dependent manner

  2018cites this paper
• CaGdt1 plays a compensatory role for the calcium pump CaPmr1 in the regulation of calcium signaling and cell wall integrity signaling in Candida albicans

  2018cites this paper
• Cellular Consequences of Diminished Protein O-Mannosyltransferase Activity in Baker’s Yeast

  2017cites this paper
• The CWI Pathway: Regulation of the Transcriptional Adaptive Response to Cell Wall Stress in Yeast

  2017cites this paper
• Unlocking the Therapeutic Potential of the Fungal Cell Wall: Clinical Implications and Drug Resistance

  2017cites this paper
• A novel connection between the Cell Wall Integrity and the PKA pathways regulates cell wall stress response in yeast

  2017cites this paper
• SWATH-MS Glycoproteomics Reveals Consequences of Defects in the Glycosylation Machinery*

  2016cites this paper
• Protein O-mannosylation in the early secretory pathway.

  2016cites this paper
• Development of N- and O-linked oligosaccharide engineered Saccharomyces cerevisiae strain.

  2016cites this paper
• Cooperation between SAGA and SWI/SNF complexes is required for efficient transcriptional responses regulated by the yeast MAPK Slt2

  2016cites this paper
• Examination and Disruption of the Yeast Cell Wall.

  2016cites this paper
• Effects of carbon source and light intensity on the growth and total lipid production of three microalgae under different culture conditions

  2016cites this paper
• Candida albicans responds to glycostructure damage by Ace2‐mediated feedback regulation of Cek1 signaling

  2016cites this paper
• Role of Saccharomyces cerevisiae PMT 1 in endoplasmic reticulum stress response

  2016influential citation
• Mapping the O-Mannose Glycoproteome in Saccharomyces cerevisiae

  2016cites this paper
• Protein O-mannosylation is crucial for human mesencyhmal stem cells fate

  2015cites this paper
• Progress in Yeast Glycosylation Engineering.

  2015cites this paper
• PMT1 deficiency enhances basal UPR activity and extends replicative lifespan of Saccharomyces cerevisiae

  2015cites this paper
• Hansenula polymorpha Pmt4p Plays Critical Roles in O-Mannosylation of Surface Membrane Proteins and Participates in Heteromeric Complex Formation

  2015cites this paper
• Engineering yeast for producing human glycoproteins: where are we now?

  2015cites this paper
• Discovery of a nucleocytoplasmic O-mannose glycoproteome in yeast

  2015cites this paper
• Comparative Analysis of Protein Glycosylation Pathways in Humans and the Fungal Pathogen Candida albicans

  2014cites this paper
• Protein O-Mannosyltransferases Associate with the Translocon to Modify Translocating Polypeptide Chains*

  2014cites this paper
• ERAD and how viruses exploit it

  2014cites this paper
• A Phenylalanine to Serine Substitution within an O-Protein Mannosyltransferase Led to Strong Resistance to PMT-Inhibitors in Pichia pastoris

  2013cites this paper
• Protein O-mannosylation: what we have learned from baker's yeast.

  2013cites this paper
• Reverse Engineering Molecular Hypergraphs

  2013cites this paper
• Protein O-mannosylation is crucial for E-cadherin–mediated cell adhesion

  2013cites this paper
• Functional and molecular characterization of novel Hansenula polymorpha genes, HpPMT5 and HpPMT6, encoding protein O-mannosyltransferases.

  2013cites this paper
• Genes involved in protein glycosylation determine the activity and cell internalization of the antifungal peptide PAF26 in Saccharomyces cerevisiae.

  2013cites this paper
• Characterization of the Pichia pastoris Protein-O-mannosyltransferase Gene Family

  2013influential citation
• Architecture and Biosynthesis of the Saccharomyces cerevisiae Cell Wall

  2012cites this paper
• Mtl1 O-mannosylation mediated by both Pmt1 and Pmt2 is important for cell survival under oxidative conditions and TOR blockade.

  2012cites this paper
• More than 40 years of glycobiology in Regensburg.

  2012cites this paper
• The essential endoplasmic reticulum chaperone Rot1 is required for protein N- and O-glycosylation in yeast.

  2012cites this paper
• Aberrant substrate engagement of the ER translocon triggers degradation by the Hrd1 ubiquitin ligase

  2012cites this paper
• Chromatin remodeling by the SWI/SNF complex is essential for transcription mediated by the yeast cell wall integrity MAPK pathway

  2012cites this paper
• Genome-wide survey of yeast mutations leading to activation of the yeast cell integrity MAPK pathway: Novel insights into diverse MAPK outcomes

  2011cites this paper
• A Conserved Acidic Motif Is Crucial for Enzymatic Activity of Protein O-Mannosyltransferases*

  2011cites this paper