Aberrant substrate engagement of the ER translocon triggers degradation by the Hrd1 ubiquitin ligase

E. Rubenstein,S. Kreft,W. Greenblatt,R. Swanson,M. Hochstrasser

Published 2012 in Journal of Cell Biology

ABSTRACT

The Hrd1 ubiquitin ligase plays a role in quality control of two substrates associated with the Sec61 translocon.

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