Molecular model for a complete clathrin lattice from electron cryomicroscopy

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Nature

• Publication date

  2004-12-02

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1038/nature03079PMID 15502812
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Structure of an auxilin-bound clathrin coat and its implications for the mechanism of uncoating

  2004cited by this paper
• University of Groningen Endocytosis by Random Initiation and Stabilization of Clathrin-Coated Pits

  2004cited by this paper
• Adaptable adaptors for coated vesicles.

  2004cited by this paper
• Optimal determination of particle orientation, absolute hand, and contrast loss in single-particle electron cryomicroscopy.

  2003cited by this paper
• Accurate determination of local defocus and specimen tilt in electron microscopy.

  2003cited by this paper
• Clathrin light and heavy chain interface: α‐helix binding superhelix loops via critical tryptophans

  2002cited by this paper
• Biological basket weaving: formation and function of clathrin-coated vesicles.

  2001cited by this paper
• Comparative protein structure modeling of genes and genomes.

  2000cited by this paper
• Single-particle electron cryo-microscopy: towards atomic resolution

  2000cited by this paper
• Ximdisp--A visualization tool to aid structure determination from electron microscope images.

  1999cited by this paper
• Clathrin self-assembly is mediated by a tandemly repeated superhelix

  1999cited by this paper
• EMAN: semiautomated software for high-resolution single-particle reconstructions.

  1999cited by this paper
• Software for handling macromolecular envelopes.

  1999cited by this paper
• Functional organization of clathrin in coats: combining electron cryomicroscopy and X-ray crystallography.

  1999cited by this paper
• Atomic Structure of Clathrin : A b Propeller Terminal Domain Joins an a Zigzag Linker

  1998cited by this paper
• Atomic structure of clathrin: a beta propeller terminal domain joins an alpha zigzag linker.

  1998cited by this paper
• Clathrin coats at 21 Å resolution: a cellular assembly designed to recycle multiple membrane receptors

  1998cited by this paper
• Three-dimensional structure of bovine NADH:ubiquinone oxidoreductase (complex I) at 22 A in ice.

  1998cited by this paper
• A new generation of the IMAGIC image processing system.

  1996cited by this paper
• Regulation of clathrin assembly and trimerization defined using recombinant triskelion hubs.

  1995cited by this paper
• Role of auxilin in uncoating clathrin-coated vesicles

  1995cited by this paper
• The CCP4 suite: programs for protein crystallography.

  1994cited by this paper
• Immunoelectron microscopic evidence for the extended conformation of light chains in clathrin trimers.

  1993cited by this paper
• Comparative protein modelling by satisfaction of spatial restraints.

  1993cited by this paper
• Folding and trimerization of clathrin subunits at the triskelion hub.

  1992cited by this paper
• Improved methods for building protein models in electron density maps and the location of errors in these models.

  1991cited by this paper
• Analysis of clathrin light chain-heavy chain interactions using truncated mutants of rat liver light chain LCB3.

  1990cited by this paper
• Stabilization of clathrin coats by the core of the clathrin-associated protein complex AP-2.

  1990cited by this paper
• Clathrin light chains contain brain-specific insertion sequences and a region of homology with intermediate filaments

  1987cited by this paper
• Clathrin light chains LCA and LCB are similar, polymorphic, and share repeated heptad motifs.

  1987cited by this paper
• Three‐dimensional structure of clathrin cages in ice.

  1986cited by this paper
• Location of the 100 kd‐50 kd accessory proteins in clathrin coats.

  1986cited by this paper
• Exact filters for general geometry three dimensional reconstruction

  1986cited by this paper
• Configuration of clathrin trimers: evidence from electron microscopy.

  1986cited by this paper
• Location and distribution of the light chains in clathrin trimers.

  1983cited by this paper
• Biochemical and immunological studies on clathrin light chains and their binding sites on clathrin triskelions.

  1983cited by this paper
• Assembly units of clathrin coats

  1981cited by this paper
• Protein organization in clathrin trimers.

  1981cited by this paper
• Three-dimensional visualization of coated vesicle formation in fibroblasts

  1980cited by this paper
• On the structure of coated vesicles.

  1976cited by this paper
• Notizen: Zur Defokussierungsabhängigkeit des Phasenkontrastes bei der elektronenmikroskopischen Abbildung

  1966cited by this paper

• ClathPLM: Deep multi-view feature extraction with CNN and attention enhances clathrin protein identification.

  2026cites this paper
• Structuring of the endolysosomal system by HOPS and CORVET tethering complexes.

  2025cites this paper
• Aptamers and endocytosis: The path into tumor cells.

  2025cites this paper
• An M60L60 metal-peptide capsid with a 60-crossing woven network

  2025cites this paper
• A new statistical metric for robust target detection in cryo-EM using 2D template matching

  2025cites this paper
• Spatial organization of phosphoinositide signaling.

  2025cites this paper
• Blueberries Reduce Palm Oil‐Induced Metabolic Endotoxemia in an In Vitro Human Intestinal‐Immune Cell Model

  2025cites this paper
• Topological defect engineering enables size and shape control in self-assembly

  2025cites this paper
• Resolving protein organization in cells with nanometer resolution

  2025influential citation
• Of condensates and coats - reciprocal regulation of clathrin assembly and the growth of protein networks

  2025cites this paper
• AI-Guided Stability Tuning of a Heterodimeric Linker for Programmable Protein Tube Architectures

  2025cites this paper
• Cryo-electron tomography pipeline for plasma membranes

  2025cites this paper
• Design of supports based on S-layer proteins-poly(acrylic) particles with varying surface properties.

  2025cites this paper
• Visualization of lysosomal membrane proteins by cryo electron tomography

  2025cites this paper
• Protein Cage-like Vesicles Fabricated via Polymerization-Induced Microphase Separation of Amphiphilic Diblock Copolymers

  2025cites this paper
• Of condensates and coats - reciprocal regulation of clathrin assembly and the growth of protein networks

  2025cites this paper
• Dynamin independent endocytosis is an alternative cell entry mechanism for multiple animal viruses

  2024cites this paper
• Clathrin assemblies at a glance.

  2024cites this paper
• CHC22 clathrin recruitment to the early secretory pathway requires two-site interaction with SNX5 and p115

  2024cites this paper
• Clathrin-Mediated Endocytosis of Multiple Nanoparticles Tends to Be Less Cooperative: A Computational Study.

  2024cites this paper
• Molecular architecture of synaptic vesicles

  2024cites this paper
• Mechanistic divergences of endocytic clathrin-coated vesicle formation in mammals, yeasts and plants

  2024influential citation
• Induced degradation of SNAP-fusion proteins

  2024cites this paper
• Vesiculation pathways in clathrin-mediated endocytosis

  2024cites this paper
• Coat stiffening can explain invagination of clathrin-coated membranes.

  2024cites this paper
• Introduction of the Capsules environment to support further growth of the SBGrid structural biology software collection

  2024cites this paper
• Clathrin coats partially preassemble and subsequently bend during endocytosis

  2023cites this paper
• Alternative cell entry mechanisms for SARS-CoV-2 and multiple animal viruses

  2023cites this paper
• A computational study of the influence of nanoparticle shape on clathrin-mediated endocytosis.

  2023cites this paper
• Patterns of human and porcine gammaherpesvirus-encoded BILF1 receptor endocytosis

  2023cites this paper
• Endocytosis gated by emergent properties of membrane-clathrin interactions

  2023cites this paper
• α-Synuclein colocalizes with AP180 and affects the size of clathrin lattices

  2023cites this paper
• Shape‐Anisotropic Assembly of Protein Nanocages with Identical Building Blocks by Designed Intermolecular π–π Interactions

  2023cites this paper
• The recurrent pathogenic Pro890Leu substitution in CLTC causes a generalized defect in synaptic transmission in Caenorhabditis elegans

  2023cites this paper
• Close packings of identical proteins in small spherical capsids and similar proteinaceous shells.

  2023cites this paper
• Regulation of cargo exocytosis by a Reps1-Ralbp1-RalA module

  2023cites this paper
• Capturing the mechanics of clathrin-mediated endocytosis.

  2022cites this paper
• Construction and Functionalization of a Clathrin Assembly for a Targeted Protein Delivery.

  2022cites this paper
• MIT Open Access

  2022cites this paper
• A Clathrin light chain A reporter mouse for in vivo imaging of endocytosis

  2022cites this paper
• The beauty of simplicity in membrane biology

  2022cites this paper
• Three-dimensional visualization of planta clathrin-coated vesicles at ultrastructural resolution.

  2022cites this paper
• Generation of nanoscopic membrane curvature for membrane trafficking

  2022cites this paper
• Biomimetic ultrathin pepsomes for photo-controllable catalysis

  2022cites this paper
• IFT-A Structure Reveals Carriages for Membrane Protein Transport into Cilia

  2022cites this paper
• Selective membrane wrapping on differently sized nanoparticles regulated by clathrin assembly: A computational model.

  2022cites this paper
• Mercury-instructed assembly (MiA): architecting clathrin triskelion-inspired highly functional C3-symmetric triskelion nanotorus functional structures into microtorus structures.

  2022cites this paper
• User-friendly electron microscopy protocols for the visualization of biological macromolecular complexes in three dimensions: Visualization of planta clathrin-coated vesicles at ultrastructural resolution

  2022cites this paper
• Reconstituting and Purifying Assembly Intermediates of Clathrin Adaptors AP1 and AP2.

  2022cites this paper
• A conformational switch in clathrin light chain regulates lattice structure and endocytosis at the plasma membrane of mammalian cells

  2022cites this paper
• Functional Diversity of Macropinocytosis.

  2022cites this paper
• Large self-assembled clathrin lattices spontaneously disassemble without sufficient adaptor proteins

  2022cites this paper
• Protein phase separation hotspots at the presynapse

  2022cites this paper
• Vesicle trafficking and vesicle fusion: mechanisms, biological functions, and their implications for potential disease therapy

  2022cites this paper
• Molecular Mechanisms of Steric Pressure Generation and Membrane Remodeling by Intrinsically Disordered Proteins

  2022cites this paper
• Characterization of CAP1 and ECA4 adaptors participating in clathrin-mediated endocytosis

  2022cites this paper
• Role of Clathrin and Dynamin in Clathrin Mediated Endocytosis/Synaptic Vesicle Recycling and Implications in Neurological Diseases

  2022cites this paper
• Supramolecular assembly of protein building blocks: from folding to function

  2022cites this paper
• Symmetric tangled Platonic polyhedra

  2022cites this paper
• Virus Assembly Pathways Inside a Host Cell.

  2022cites this paper
• Clathrin-mediated endocytosis cooperates with bulk endocytosis to generate vesicles

  2022cites this paper
• Hierarchical Self-Assembly of Adhesive and Conductive Gels with Anion-Coordinated Triple Helicate Junctions.

  2022cites this paper
• Subcellular trafficking and post-translational modification regulate PIN polarity in plants

  2022cites this paper
• Probing Intracellular Vesicle Trafficking and Membrane Remodelling by Cryo-EM.

  2022cites this paper
• Bionanomaterials based on protein self-assembly: Design and applications in biotechnology.

  2021cites this paper
• Multi‐modal adaptor‐clathrin contacts drive coated vesicle assembly

  2021cites this paper
• AAGAB is an assembly chaperone regulating AP1 and AP2 clathrin adaptors.

  2021cites this paper
• De novo transcriptome sequencing, assembly, and gene expression profiling of a salt-stressed halophyte (Salsola drummondii) from a saline habitat.

  2021cites this paper
• Nanodissected elastically loaded clathrin lattices relax to increased curvature

  2021influential citation
• Structure of the RZZ complex and molecular basis of Spindly‐driven corona assembly at human kinetochores

  2021cites this paper
• Clathrin: the molecular shape shifter.

  2021cites this paper
• Hierarchical Nanomaterials Assembled from Peptoids and Other Sequence-Defined Synthetic Polymers.

  2021cites this paper
• Nascent clathrin lattices spontaneously disassemble without sufficient adaptor proteins

  2021cites this paper
• Arrestin-dependent and -independent internalization of GPCRs-methods, mechanisms and implications on cell signaling

  2021cites this paper
• Clathrin Heavy Chain 1 Plays Essential Roles During Oocyte Meiotic Spindle Formation and Early Embryonic Development in Sheep

  2021cites this paper
• Endocytosis against high turgor pressure is made easier by partial protein coating and a freely rotating base.

  2021cites this paper
• Arrestin-Dependent and -Independent Internalization of G Protein–Coupled Receptors: Methods, Mechanisms, and Implications on Cell Signaling

  2021cites this paper
• Dynamin-2 mediates clathrin-dependent endocytosis for amyloid-β internalization in brain microvascular endothelial cells.

  2021cites this paper
• Networks of interacting proteins contribute to membrane curvature sensing.

  2021cites this paper
• Morphological and functional characterization of host proteins during infections by actin-hijacking bacterial pathogens

  2020cites this paper
• Competing pathways for the invagination of clathrin-coated membranes.

  2020cites this paper
• The Missing Link: Au191(SPh-tBu)66 Janus Nanoparticle with Molecular and Bulk-Metal-like Properties.

  2020cites this paper
• Architecture of the AP2/clathrin coat on the membranes of clathrin-coated vesicles

  2020cites this paper
• Tailoring Iron Oxide Nanoparticles for Efficient Cellular Internalization and Endosomal Escape

  2020cites this paper
• The structures of natively assembled clathrin-coated vesicles

  2020cites this paper
• Wbox2: A clathrin terminal domain–derived peptide inhibitor of clathrin-mediated endocytosis

  2020cites this paper
• Eden growth models for flat clathrin lattices with vacancies

  2020cites this paper
• Clathrin light chain diversity regulates membrane deformation in vitro and synaptic vesicle formation in vivo

  2020cites this paper
• Structural and Biochemical Properties of Hsp40/Hsp70 Chaperone System.

  2020cites this paper
• Alternative splicing of clathrin heavy chain contributes to the switch from coated pits to plaques

  2020cites this paper
• Architecture of the AP2:clathrin coat on the membranes of clathrin-coated vesicles

  2020cites this paper
• Self-assembly of trigonal building blocks into nanostructures: molecular design and biomedical applications.

  2020cites this paper
• The Structures of Natively Assembled Clathrin Coated Vesicles

  2020cites this paper
• Clathrin Senses Membrane Curvature

  2020influential citation
• From cellular microbiology to bacteria‐based next generations of cancer immunotherapies

  2020influential citation
• Slow Axonal Transport and Presynaptic Targeting of Clathrin Packets

  2020cites this paper
• Structure-based inhibitors reveal roles for the clathrin terminal domain and its W-box binding site in CME

  2020cites this paper
• CLATHRIN LIGHT CHAIN DIVERSITY REGULATES MEMBRANE DEFORMATION IN 3 VITRO AND SYNAPTIC VESICLE FORMATION IN VIVO

  2020cites this paper
• Interactions at the cell membrane and pathways of internalization of nano-sized materials for nanomedicine

  2020cites this paper
• CLATHRIN LIGHT CHAIN DIVERSITY REGULATES BUDDING EFFICIENCY IN VITRO 3 AND SYNAPTIC VESICLE FORMATION IN VIVO 4 5 6

  2020cites this paper