Therapeutic Options for Sleep‐Maintenance and Sleep‐Onset Insomnia

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Pharmacotherapy

• Publication date

  2007-01-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1592/phco.27.1.89PMID 17192164
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Valerian.

  2020cited by this paper
• Sleep problems and their correlates in a working population

  2007cited by this paper
• An efficacy, safety, and dose-response study of Ramelteon in patients with chronic primary insomnia.

  2006cited by this paper
• Ramelteon (TAK-375), a selective MT1/MT2-receptor agonist, reduces latency to persistent sleep in a model of transient insomnia related to a novel sleep environment.

  2005cited by this paper
• Eszopiclone (Lunesta), a new hypnotic.

  2005cited by this paper
• Cognitive-Behavioral Group Therapy as an Early Intervention for Insomnia: A Randomized Controlled Trial

  2005cited by this paper
• Virtual Colonoscopy

  2005cited by this paper
• Diagnosis and treatment of chronic insomnia: a review.

  2005cited by this paper
• A 2-week efficacy and safety study of eszopiclone in elderly patients with primary insomnia.

  2005cited by this paper
• Ramelteon

  2005cited by this paper
• Caloric Restriction and Caloric Restriction Mimetics: Current Status and Promise for the Future

  2005cited by this paper
• A review of the evidence for the efficacy and safety of trazodone in insomnia.

  2005cited by this paper
• Fresh from the pipeline: Ramelteon.

  2005cited by this paper
• Clinical practice. Chronic insomnia.

  2005cited by this paper
• Effects of exogenous melatonin on sleep: a meta-analysis.

  2005cited by this paper
• An evaluation of the efficacy and safety of eszopiclone over 12 months in patients with chronic primary insomnia.

  2005cited by this paper
• Positioning of the alpha-subunit isoforms confers a functional signature to gamma-aminobutyric acid type A receptors.

  2004cited by this paper
• Special considerations in insomnia diagnosis and management: depressed, elderly, and chronic pain populations.

  2004cited by this paper
• The Pharmacology and Mechanisms of Action of New Generation, Non-Benzodiazepine Hypnotic Agents

  2004cited by this paper
• Characterization of the Interaction of Indiplon, a Novel Pyrazolopyrimidine Sedative-Hypnotic, with the GABAA Receptor

  2004cited by this paper
• Overview of the Therapeutic Management of Insomnia with Zolpidem

  2004cited by this paper
• The treatment of chronic insomnia: drug indications, chronic use and abuse liability. Summary of a 2001 New Clinical Drug Evaluation Unit meeting symposium.

  2004cited by this paper
• In Vivo Pharmacological Characterization of Indiplon, a Novel Pyrazolopyrimidine Sedative-Hypnotic

  2004cited by this paper
• The Gamma-Aminobutyric Acidergic Effects of Valerian and Valerenic Acid on Rat Brainstem Neuronal Activity

  2004cited by this paper
• Melatonin, sleep, and circadian rhythms: rationale for development of specific melatonin agonists.

  2004cited by this paper
• A systematic review of non-pharmacological therapies for sleep problems in later life.

  2004cited by this paper
• Cognitive-behavioral approaches to the treatment of insomnia.

  2004cited by this paper
• Symptoms and circuits, part 3: schizophrenia.

  2004cited by this paper
• Acetaminophen preferable to ibuprofen for pretreatment of electroconvulsive therapy-induced headache.

  2004cited by this paper
• Positioning of the α-subunit isoforms confers a functional signature to γ-aminobutyric acid type A receptors

  2004cited by this paper
• Clinical and socioeconomic correlates of insomnia.

  2004cited by this paper
• Cognitive behavior therapy and pharmacotherapy for insomnia: a randomized controlled trial and direct comparison.

  2004cited by this paper
• Measuring treatment efficacy in insomnia.

  2004cited by this paper
• Issues in the clinical use of benzodiazepines: potency, withdrawal, and rebound.

  2004cited by this paper
• Identification and management of insomnia.

  2004cited by this paper
• Pharmacologic management of insomnia.

  2004cited by this paper
• Efficacy and safety of eszopiclone across 6-weeks of treatment for primary insomnia

  2004cited by this paper
• Use of sleep hygiene in the treatment of insomnia.

  2003cited by this paper
• Sustained efficacy of eszopiclone over 6 months of nightly treatment: results of a randomized, double-blind, placebo-controlled study in adults with chronic insomnia.

  2003cited by this paper
• Treatment of primary insomnia with melatonin: a double-blind, placebo-controlled, crossover study.

  2003cited by this paper
• New Drugs for Insomnia

  2003cited by this paper
• Sedation and performance impairment of diphenhydramine and second-generation antihistamines: a meta-analysis.

  2003cited by this paper
• Poor sleep increases the prospective risk for recurrent events in middle-aged women with coronary disease. The Stockholm Female Coronary Risk Study.

  2003cited by this paper
• Subunit composition, distribution and function of GABA(A) receptor subtypes.

  2002cited by this paper
• Comparative meta-analysis of pharmacotherapy and behavior therapy for persistent insomnia.

  2002cited by this paper
• Medical and socio-professional impact of insomnia.

  2002cited by this paper
• Prevalence of sleep problems and quality of life in an older population.

  2002cited by this paper
• Comparison of the effects of zaleplon, zolpidem, and triazolam at various GABA(A) receptor subtypes.

  2002cited by this paper
• The relationship between insomnia and health-related quality of life in patients with chronic illness.

  2002cited by this paper
• Continuous versus non-nightly use of zolpidem in chronic insomnia: results of a large-scale, double-blind, randomized, outpatient study

  2002cited by this paper
• Tolerance to Daytime Sedative Effects of H1 Antihistamines

  2002cited by this paper
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  2001cited by this paper
• Efficacy and Safety of Zolpidem Administered ‘As Needed’ in Primary Insomnia

  2001cited by this paper
• A Double-Blind Comparative Study of Zolpidem versus Zopiclone in the Treatment of Chronic Primary Insomnia

  2001cited by this paper
• Sleep disturbances and mood disorders: An epidemiologic perspective

  2001cited by this paper
• Cognitive behavioral therapy for treatment of chronic primary insomnia: a randomized controlled trial.

  2001cited by this paper
• Melatonin treatment for age-related insomnia.

  2001cited by this paper
• Effect of alpha subunit on allosteric modulation of ion channel function in stably expressed human recombinant gamma-aminobutyric acid(A) receptors determined using (36)Cl ion flux.

  2001cited by this paper
• Hepatitis associated with Kava, a herbal remedy for anxiety

  2001cited by this paper
• Dietary supplements: how they are used and regulated.

  2001cited by this paper
• Effect of α Subunit on Allosteric Modulation of Ion Channel Function in Stably Expressed Human Recombinant γ-Aminobutyric AcidA Receptors Determined Using 36Cl Ion Flux

  2001cited by this paper
• Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABAA receptor α1 subtype

  2000cited by this paper
• Zaleplon improves sleep without producing rebound effects in outpatients with insomnia

  2000cited by this paper
• Lack of Residual Sedation Following Middle-of-the-Night Zaleplon Administration in Sleep Maintenance Insomnia

  2000cited by this paper
• Valerian for insomnia: a systematic review of randomized clinical trials.

  2000cited by this paper
• Zaleplon shortens subjective sleep latency and improves subjective sleep quality in elderly patients with insomnia

  2000cited by this paper
• Dose‐response effects of zaleplon as compared with triazolam (0·25 mg) and placebo in chronic primary insomnia

  2000cited by this paper
• Efficacy and safety of herbal stimulants and sedatives in sleep disorders.

  2000influential reference
• Comparison of the effects of zaleplon, zolpidem, and triazolam on memory, learning, and psychomotor performance.

  2000cited by this paper
• Eight weeks of non-nightly use of zolpidem for primary insomnia.

  2000cited by this paper
• A five week, polysomnographic assessment of zaleplon 10 mg for the treatment of primary insomnia.

  2000cited by this paper
• Meta-analysis of benzodiazepine use in the treatment of insomnia.

  2000cited by this paper
• Practice parameters for the evaluation of chronic insomnia. An American Academy of Sleep Medicine report. Standards of Practice Committee of the American Academy of Sleep Medicine.

  2000cited by this paper
• Sleep latency is shortened during 4 weeks of treatment with zaleplon, a novel nonbenzodiazepine hypnotic. Zaleplon Clinical Study Group.

  1999cited by this paper
• Ten-year trends in the pharmacological treatment of insomnia.

  1999cited by this paper
• Practice parameters for the nonpharmacologic treatment of chronic insomnia. An American Academy of Sleep Medicine report. Standards of Practice Committee of the American Academy of Sleep Medicine.

  1999cited by this paper
• Zaleplon, A Novel Nonbenzodiazepine Hypnotic, Effectively Treats Insomnia in Elderly Patients Without Causing Rebound Effects.

  1999influential reference
• Nonpharmacologic treatment of chronic insomnia. An American Academy of Sleep Medicine review.

  1999influential reference
• Quality of life in people with insomnia.

  1999cited by this paper
• Behavioral and pharmacological therapies for late-life insomnia: a randomized controlled trial.

  1999cited by this paper
• Daytime consequences and correlates of insomnia in the United States: results of the 1991 National Sleep Foundation Survey. II.

  1999cited by this paper
• Nonpharmacologic Treatment of Chronic Insomnia

  1999cited by this paper
• Residual effects of evening and middle‐of‐the‐night administration of zaleplon 10 and 20 mg on memory and actual driving performance

  1998cited by this paper
• The Scientific Basis for the Reputed Activity of Valerian

  1998cited by this paper
• Insomnia, Health-Related Quality of Life and Healthcare Resource Consumption

  1998cited by this paper
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  1998cited by this paper
• Are sleep disturbances risk factors for anxiety, depressive and addictive disorders?

  1998cited by this paper
• Are sleep disturbances risk factors for anxiety, depressive and addictive disorders?

  1998cited by this paper
• Subjective hypnotic efficacy of trazodone and zolpidem in DSMIII–R primary insomnia

  1998cited by this paper
• Prevalence, burden, and treatment of insomnia in primary care.

  1997cited by this paper
• Minimal rebound insomnia after treatment with 10-mg zolpidem.

  1997cited by this paper
• Double‐blind, placebo‐controlled comparison of zolpidem, triazolam, and temazepam in elderly patients with insomnia

  1997cited by this paper
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  1997cited by this paper
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  1997cited by this paper
• Hypnotic effects of low doses of quazepam in older insomniacs.

  1997cited by this paper
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  1996cited by this paper
• Effects of triazolam on sleep, daytime sleepiness, and morning stiffness in patients with rheumatoid arthritis.

  1996cited by this paper
• Zolpidem in the treatment of transient insomnia: a double-blind, randomized comparison with placebo.

  1995cited by this paper
• Zolpidem in Insomnia: A 3-Year Post-Marketing Surveillance Study in Switzerland

  1995cited by this paper
• An eosinophilia-myalgia syndrome related disorder associated with exposure to L-5-hydroxytryptophan.

  1994cited by this paper

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  2013cites this paper
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  2011cites this paper
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  2011cites this paper
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  2011cites this paper
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  2009cites this paper
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  2009cites this paper
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  2009cites this paper
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  2009cites this paper
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