Modulation of potassium channel gating by coexpression of Kv2.1 with regulatory Kv5.1 or Kv6.1 α-subunits.

No abstract is available for this paper.

• Publication year

  1998

• Venue

  American Journal of Physiology - Cell Physiology

• Publication date

  1998-06-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1152/ajpcell.1998.274.6.C1501PMID 9696692
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Inactivation determined by a single site in K+ pores

  2004cited by this paper
• Inactivation of Kv2.1 potassium channels.

  1998cited by this paper
• A Novel Subunit for Shal K+ Channels Radically Alters Activation and Inactivation

  1997cited by this paper
• Modes of Regulation of Shab K+ Channel Activity by the Kv8.1 Subunit*

  1997cited by this paper
• Identification and Functional Characterization of a K+ Channel α-Subunit with Regulatory Properties Specific to Brain

  1997cited by this paper
• New Modulatory α Subunits for Mammalian ShabK+ Channels*

  1997cited by this paper
• Accumulation of long-lasting inactivation in rat brain K+-channels

  1996cited by this paper
• Kv2.1 and electrically silent Kv6.1 potassium channel subunits combine and express a novel current

  1996cited by this paper
• A new algorithm for idealizing single ion channel data containing multiple unknown conductance levels.

  1996cited by this paper
• Kv8.1, a new neuronal potassium channel subunit with specific inhibitory properties towards Shab and Shaw channels.

  1996cited by this paper
• The Role of K+ Currents in Frequency-Dependent Spike Broadening in Aplysia R20 Neurons: A Dynamic-Clamp Analysis

  1996cited by this paper
• C-type inactivation of a voltage-gated K+ channel occurs by a cooperative mechanism.

  1995cited by this paper
• Cooperative subunit interactions in C-type inactivation of K channels.

  1995cited by this paper
• Functional role of a conserved aspartate in the external mouth of voltage-gated potassium channels.

  1995cited by this paper
• Auxiliary subunits of voltage-gated ion channels.

  1994cited by this paper
• Inactivation properties of voltage-gated K+ channels altered by presence of β-subunit

  1994cited by this paper
• Na+ channels must deactivate to recover from inactivation.

  1994cited by this paper
• Auxiliary subunits of voltage-gated ion channels.

  1994cited by this paper
• Potassium Channels in Mammalian Brain: A Molecular Approach

  1994cited by this paper
• Functional interactions between K+ pore residues located in different subunits.

  1993cited by this paper
• Distinct spatial and temporal expression patterns of K+ channel mRNAs from different subfamilies

  1992cited by this paper
• A novel K+ channel with unique localizations in mammalian brain: molecular cloning and characterization.

  1992cited by this paper
• Specification of subunit assembly by the hydrophilic amino-terminal domain of the Shaker potassium channel.

  1992cited by this paper
• The aromatic binding site for tetraethylammonium ion on potassium channels.

  1992cited by this paper
• Tetraethylammonium blockade distinguishes two inactivation mechanisms in voltage-activated K+ channels.

  1991cited by this paper
• Shaker, Shal, Shab, and Shaw express independent K+ current systems.

  1991cited by this paper
• Evidence for the formation of heteromultimeric potassium channels in Xenopus oocytes

  1990cited by this paper
• Alteration and restoration of K+ channel function by deletions at the N- and C-termini.

  1990cited by this paper
• A novel potassium channel with delayed rectifier properties isolated from rat brain by expression cloning

  1989cited by this paper
• Temporal integration by a slowly inactivating K+ current in hippocampal neurons

  1988cited by this paper
• Mechanism of frequency‐dependent broadening of molluscan neurone soma spikes.

  1979cited by this paper
• Inactivation of the sodium channel. II. Gating current experiments

  1977cited by this paper

• Kv2/Kv6.4 Heteromeric Potassium Channels Are Expressed in Spinal Motoneurons and Localized at C‐Bouton Synapses

  2025cites this paper
• The Shab family potassium channels are highly enriched at the presynaptic terminals of human neurons

  2025cites this paper
• The Electrically Silent Kv5.1 Subunit Forms Heteromeric Kv2 Channels in Cortical Neurons and Confers Distinct Functional Properties

  2025cites this paper
• Molecular and cellular rhythms in excitatory and inhibitory neurons in the mouse prefrontal cortex.

  2025cites this paper
• Regulation of Kv2.1 biogenesis and gating by candidate disease-linked Kv6.1 variants

  2025influential citation
• Regulation of Kv2.1 Channels by Kv9.1 Variants

  2025cites this paper
• Chronic treatment with fluoxetine regulates mitochondrial features and plasticity-associated transcriptomic pathways in parvalbumin-positive interneurons of prefrontal cortex

  2025cites this paper
• Kv2/Kv6.4 heteromeric potassium channels are expressed in spinal motor neurons and localized at C-bouton synapses

  2025cites this paper
• A Kv2 inhibitor combination reveals native neuronal conductances consistent with Kv2/KvS heteromers

  2024influential citation
• Electrically silent KvS subunits associate with native Kv2 channels in brain and impact diverse properties of channel function

  2024cites this paper
• Voltage Gated Ion Channels and Sleep

  2024cites this paper
• Kv2 channels contribute to neuronal activity within the vagal afferent-nTS reflex arc.

  2023cites this paper
• Adam, amigo, brain, and K channel

  2023cites this paper
• Gene therapy for chronic pain: emerging opportunities in target-rich peripheral nociceptors

  2023cites this paper
• A KCNB1 gain of function variant causes developmental delay and speech apraxia but not seizures

  2022cites this paper
• Kv5.1 antibody in epilepsy patients with unknown etiology.

  2022cites this paper
• High spatial density is associated with non-conducting Kv channels from two families.

  2022cites this paper
• KCNG1-Related Syndromic Form of Congenital Neuromuscular Channelopathy in a Crossbred Calf

  2021cites this paper
• Sleep loss drives acetylcholine- and somatostatin interneuron–mediated gating of hippocampal activity to inhibit memory consolidation

  2021cites this paper
• Dual Role of an mps-2/KCNE-Dependent Pathway in Long-Term Memory and Age-Dependent Memory Decline.

  2020cites this paper
• Molecular characterization of projection neuron subtypes in the mouse olfactory bulb

  2020cites this paper
• The Role of Potassium Channels in Chronic Stress-Induced Brain Injury.

  2020cites this paper
• Kv2.1 voltage‐gated potassium channels in developmental perspective

  2019cites this paper
• A Kinetic Map of the Homomeric Voltage-Gated Potassium Channel (Kv) Family

  2019cites this paper
• Noncanonical Ion Channel Behaviour in Pain

  2019cites this paper
• The S6 gate in regulatory Kv6 subunits restricts heteromeric K+ channel stoichiometry

  2018cites this paper
• Kv channels and vascular smooth muscle cell proliferation

  2018cites this paper
• Oddballs in the Shaker family: Kv2-related regulatory subunits

  2018cites this paper
• T2N as a new tool for robust electrophysiological modeling demonstrated for mature and adult-born dentate granule cells

  2017cites this paper
• KCNF1 is a Novel Regulator of NSCLC Cell Growth Independent of Its Potassium Ion Channel Function BY ABHINAYA BASKARAN

  2017influential citation
• Reconstruction of Cell Surface Densities of Ion Pumps, Exchangers, and Channels from mRNA Expression, Conductance Kinetics, Whole-Cell Calcium, and Current-Clamp Voltage Recordings, with an Application to Human Uterine Smooth Muscle Cells

  2016cites this paper
• La douleur sous le contrôle des canaux potassiques

  2016cites this paper
• Kv5, Kv6, Kv8, and Kv9 subunits: No simple silent bystanders

  2016cites this paper
• Expression and function of a CP339,818-sensitive K⁺ current in a subpopulation of putative nociceptive neurons from adult mouse trigeminal ganglia.

  2015cites this paper
• Functional Expression Profile of Voltage-Gated K+ Channel Subunits in Rat Small Mesenteric Arteries

  2015cites this paper
• Kv2 dysfunction after peripheral axotomy enhances sensory neuron responsiveness to sustained input

  2014cites this paper
• Differences in Human Cortical Gene Expression Match the Temporal Properties of Large-Scale Functional Networks

  2014cites this paper
• MOR Is Not Enough: Identification of Novel mu-Opioid Receptor Interacting Proteins Using Traditional and Modified Membrane Yeast Two-Hybrid Screens

  2013cites this paper
• Auxiliary KChIP4a Suppresses A-type K+ Current through Endoplasmic Reticulum (ER) Retention and Promoting Closed-state Inactivation of Kv4 Channels*

  2013cites this paper
• Functional Analysis of Missense Mutations in Kv8.2 Causing Cone Dystrophy with Supernormal Rod Electroretinogram*

  2012cites this paper
• KV2.1 and electrically silent KV channel subunits control excitability and contractility of guinea pig detrusor smooth muscle.

  2012cites this paper
• Electrically silent Kv subunits: their molecular and functional characteristics.

  2012cites this paper
• Expanded Functional Diversity of Shaker K+ Channels in Cnidarians Is Driven by Gene Expansion

  2012cites this paper
• Mechanisms of closed‐state inactivation in voltage‐gated ion channels

  2011cites this paper
• Nitric Oxide Is an Activity-Dependent Regulator of Target Neuron Intrinsic Excitability

  2011cites this paper
• A model of the interaction between N-type and C-type inactivation in Kv1.4 channels.

  2011cites this paper
• Contribution of Kv2.1 channels to the delayed rectifier current in freshly dispersed smooth muscle cells from rabbit urethra.

  2011cites this paper
• Dissection of the voltage-activated potassium outward currents in adult mouse ventricular myocytes: Ito,f, Ito,s, IK,slow1, IK,slow2, and Iss

  2011cites this paper
• Stromatoxin‐sensitive, heteromultimeric Kv2.1/Kv9.3 channels contribute to myogenic control of cerebral arterial diameter

  2010cites this paper
• Formation of Heteromeric Kv2 Channels in Mammalian Brain Neurons*

  2010cites this paper
• Expression and Function of the Potassium Channels of the Human Heart

  2010cites this paper
• Kv2.1 and silent Kv subunits underlie the delayed rectifier K+ current in cultured small mouse DRG neurons.

  2009cites this paper
• De novo expression of Kv6.3 contributes to changes in vascular smooth muscle cell excitability in a hypertensive mice strain

  2009cites this paper
• Conserved Negative Charges in the N-terminal Tetramerization Domain Mediate Efficient Assembly of Kv2.1 and Kv2.1/Kv6.4 Channels*

  2009cites this paper
• Expression and distribution of voltage-gated ion channels in ferret sinoatrial node.

  2009cites this paper
• Mutation of Histidine 105 in the T1 Domain of the Potassium Channel Kv2.1 Disrupts Heteromerization with Kv6.3 and Kv6.4*

  2009cites this paper
• Animal toxins acting on voltage-gated potassium channels.

  2008cites this paper
• THE ROLE OF THE TRANSCRIPTION FACTOR NFAT IN THE REGULATION OF SMOOTH MUSCLE CONTRACTILITY

  2008cites this paper
• What are the roles of the many different types of potassium channel expressed in cerebellar granule cells?

  2008cites this paper
• An investigation of NAADP-dependent Ca²⁺ signalling mechanisms in arterial smooth muscle

  2007cites this paper
• Kv2 subunits underlie slowly inactivating potassium current in rat neocortical pyramidal neurons

  2007influential citation
• Characterization of the heteromeric potassium channel formed by kv2.1 and the retinal subunit kv8.2 in Xenopus oocytes.

  2007cites this paper
• Molecular determinants of voltage-gated potassium currents in vascular smooth muscle

  2007cites this paper
• Ionic Channel Function in Action Potential Generation: Current Perspective

  2007cites this paper
• Voltage‐Gated Ion Channels

  2007cites this paper
• Voltage-Gated Potassium Channels

  2007cites this paper
• Bone morphogenetic protein-2 upregulates expression and function of voltage-gated K+ channels in human pulmonary artery smooth muscle cells.

  2006cites this paper
• Kv2 channels oppose myogenic constriction of rat cerebral arteries.

  2006cites this paper
• Gene expression profiling of human cardiac potassium and sodium channels.

  2006cites this paper
• K+ Channels in Apoptosis

  2006cites this paper
• Fluorescence measurements reveal stoichiometry of K+ channels formed by modulatory and delayed rectifier α-subunits

  2005cites this paper
• International Union of Pharmacology. LII. Nomenclature and Molecular Relationships of Calcium-Activated Potassium Channels

  2005cites this paper
• Ion channels in smooth muscle: regulators of intracellular calcium and contractility.

  2005cites this paper
• Potassium channels

  2005cites this paper
• International Union of Pharmacology. LIII. Nomenclature and Molecular Relationships of Voltage-Gated Potassium Channels

  2005cites this paper
• Amino-terminal regulation of Kv channel inactivation

  2005cites this paper
• Domain analysis of Kv6.3, an electrically silent channel

  2005cites this paper
• Biophysical and pharmacological properties of the voltage‐gated potassium current of human pancreatic β‐cells

  2005cites this paper
• Selective expression of HERG and Kv2 channels influences proliferation of uterine cancer cells.

  2004cites this paper
• NFATc3 Regulates Kv2.1 Expression in Arterial Smooth Muscle*

  2004cites this paper
• Pharmacological evidence for a key role of voltage‐gated K+ channels in the function of rat aortic smooth muscle cells

  2004cites this paper
• Carboxyl tail region of the Kv2.2 subunit mediates novel developmental regulation of channel density.

  2004cites this paper
• Modification of Kv2.1 K+ currents by the silent Kv10 subunits.

  2004cites this paper
• Modification of Kv2.1 K+ currents by the silent Kv10 subunits.

  2004cites this paper
• Molecular cloning and partial functional characterization of Tsha3--a novel modulatory potassium channel alpha-subunit of trout CNS.

  2004cites this paper
• Novel Developmental Regulation of Channel Density Carboxyl Tail Region of the Kv 2 . 2 Subunit Mediates

  2004cites this paper
• Wh h l f h diff f i What are the roles of the many different types of potassium channel expressed in cerebellar granule cells

  2003cites this paper
• Role of Voltage-Gated K+ (KV) Channels in Vascular Function

  2003cites this paper
• Voltage-dependent K+ channels in pancreatic beta cells: Role, regulation and potential as therapeutic targets

  2003cites this paper
• Properties and molecular basis of the mouse urinary bladder voltage‐gated K+ current

  2003influential citation
• Structural Determinants of the Regulation of the Voltage-gated Potassium Channel Kv2.1 by the Modulatory α-Subunit Kv9.3*

  2003cites this paper
• New Expression Profiles of Voltage‐gated Ion Channels in Arteries Exposed to High Blood Pressure

  2002cites this paper
• Amino-terminal Determinants of U-type Inactivation of Voltage-gated K+ Channels*

  2002cites this paper
• Different Kv2.1/Kv9.3 heteromer expression during brain and lung post-natal development in the rat

  2002cites this paper
• AtKC1, a silent Arabidopsis potassium channel α-subunit modulates root hair K+ influx

  2002cites this paper
• Diurnal and Circadian Regulation of Putative Potassium Channels in a Leaf Moving Organ1

  2002cites this paper
• AtKC1, a silent Arabidopsis potassium channel alpha -subunit modulates root hair K+ influx.

  2002cites this paper
• K(V)2.1 channels mediate hypoxic inhibition of I(KV) in native pulmonary arterial smooth muscle cells of the rat.

  2002cites this paper
• Obligatory heterotetramerization of three previously uncharacterized Kv channel α-subunits identified in the human genome

  2002cites this paper
• The molecular physiology of the cardiac transient outward potassium current (I(to)) in normal and diseased myocardium.

  2001cites this paper