This chapter aims at giving a critical overview of the major oxidant and antioxidant changes in arterial hypertension, summarizing the experimental and clinical evidence about the involvement of oxidative stress in the pathophysiology of hypertension, either as a cause or a consequence of this disease. This review also provides a description of the biomarkers commonly used to evaluate lipid peroxidation and antioxidant defenses in experimental and human hypertension. Finally, we review the strategies (antioxidants, antihypertensive drugs) known to prevent or ameliorate oxidative damage, both in animal models of hypertension and hypertensive patients.
Lipid Peroxidation and Antioxidants in Arterial Hypertension
T. Sousa,J. Afonso,A. Albino-Teixeira,F. Carvalho
Published 2012 in Unknown venue
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- Publication year
2012
- Venue
Unknown venue
- Publication date
2012-08-29
- Fields of study
Medicine, Chemistry, Environmental Science
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