Haematopoietic stem cell release is regulated by circadian oscillations

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Nature

• Publication date

  2008-03-27

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/nature06685PMID 18256599
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Hematopoietic Stem Cell Trafficking

  2007cited by this paper
• Phagocyte-derived catecholamines enhance acute inflammatory injury

  2007cited by this paper
• Immunosurveillance by hematopoietic progenitor cells trafficking through blood, lymph, and peripheral tissues.

  2007cited by this paper
• Self-renewing osteoprogenitors in bone marrow sinusoids can organize a hematopoietic microenvironment.

  2007cited by this paper
• Catecholaminergic neurotransmitters regulate migration and repopulation of immature human CD34+ cells through Wnt signaling

  2007cited by this paper
• Circadian rhythms: mechanisms and therapeutic implications.

  2007cited by this paper
• Mammalian circadian signaling networks and therapeutic targets.

  2007cited by this paper
• Maintenance of the hematopoietic stem cell pool by CXCL12-CXCR4 chemokine signaling in bone marrow stromal cell niches.

  2006cited by this paper
• Signals from the sympathetic nervous system regulate hematopoietic stem cell egress from bone marrow.

  2006cited by this paper
• Circadian Rhythms in Heart Rate, Motility, and Body Temperature of Wild‐type C57 and eNOS Knock‐out Mice Under Light‐dark, Free‐run, and After Time Zone Transition

  2006cited by this paper
• The stem-cell niche as an entity of action

  2006cited by this paper
• G-CSF potently inhibits osteoblast activity and CXCL12 mRNA expression in the bone marrow.

  2005cited by this paper
• Functional characterization of SDF-1 proximal promoter.

  2005cited by this paper
• Evidence for Stem Cells in the Peripheral Blood of Mice

  2005cited by this paper
• The molecular clock mediates leptin-regulated bone formation.

  2005cited by this paper
• Leptin regulation of bone resorption by the sympathetic nervous system and CART

  2005cited by this paper
• Current mechanistic scenarios in hematopoietic stem/progenitor cell mobilization.

  2004cited by this paper
• Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche.

  2004cited by this paper
• Integrin alpha4beta7 and its counterreceptor MAdCAM-1 contribute to hematopoietic progenitor recruitment into bone marrow following transplantation.

  2004cited by this paper
• Integrin α4β7 and its counterreceptor MAdCAM-1 contribute to hematopoietic progenitor recruitment into bone marrow following transplantation

  2004cited by this paper
• Osteoblastic cells regulate the haematopoietic stem cell niche

  2003cited by this paper
• Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by GCSF or cyclophosphamide.

  2003cited by this paper
• PSGL-1 participates in E-selectin-mediated progenitor homing to bone marrow: evidence for cooperation between E-selectin ligands and alpha4 integrin.

  2003cited by this paper
• Galactocerebrosides are required postnatally for stromal-dependent bone marrow lymphopoiesis.

  2003cited by this paper
• Impaired osteoblastic differentiation, reduced bone formation, and severe osteoporosis in noggin-overexpressing mice.

  2003cited by this paper
• Identification of the haematopoietic stem cell niche and control of the niche size

  2003cited by this paper
• Mouse α1(I)‐collagen promoter is the best known promoter to drive efficient Cre recombinase expression in osteoblast

  2002cited by this paper
• G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4

  2002cited by this paper
• Current understanding of stem cell mobilization: the roles of chemokines, proteolytic enzymes, adhesion molecules, cytokines, and stromal cells.

  2002cited by this paper
• Lipopolysaccharide Down-regulates Sp1 Binding Activity by Promoting Sp1 Protein Dephosphorylation and Degradation*

  2002cited by this paper
• Hematopoietic Stem Cells Are Uniquely Selective in Their Migratory Response to Chemokines

  2002cited by this paper
• Mechanisms of mobilization of hematopoietic progenitors with granulocyte colony-stimulating factor

  2002cited by this paper
• Nonredundant roles of the mPer1 and mPer2 genes in the mammalian circadian clock.

  2001cited by this paper
• Sp1 Phosphorylation Regulates Apoptosis via Extracellular FasL-Fas Engagement*

  2001cited by this paper
• Physiological Migration of Hematopoietic Stem and Progenitor Cells

  2001cited by this paper
• Mop3 is an essential component of the master circadian pacemaker in mammals.

  2000cited by this paper
• The β3-Adrenergic Receptor Activates Mitogen-activated Protein Kinase in Adipocytes through a Gi-dependent Mechanism*

  1999cited by this paper
• Targeted Disruption of the β2 Adrenergic Receptor Gene*

  1999cited by this paper
• No neuronal regulation of murine bone marrow function.

  1998cited by this paper
• Endothelial selectins and vascular cell adhesion molecule-1 promote hematopoietic progenitor homing to bone marrow.

  1998cited by this paper
• Neural and endogenous catecholamines in the bone marrow. Circadian association of norepinephrine with hematopoiesis?

  1998cited by this paper
• The Chemokine SDF-1 Is a Chemoattractant for Human CD34+ Hematopoietic Progenitor Cells and Provides a New Mechanism to Explain the Mobilization of CD34+ Progenitors to Peripheral Blood

  1997cited by this paper
• Modulation of Transcription Factor Sp1 by cAMP-dependent Protein Kinase*

  1997cited by this paper
• Susceptibility to infection and altered hematopoiesis in mice deficient in both P- and E-selectins.

  1996cited by this paper
• Targeted Disruption of the β3-Adrenergic Receptor Gene *

  1995cited by this paper
• Ultrastructural morphometric study of efferent nerve terminals on murine bone marrow stromal cells, and the recognition of a novel anatomical unit: the "neuro-reticular complex".

  1990cited by this paper
• Diurnal variation of circulating human myeloid progenitor cells.

  1980cited by this paper
• Diurnal changes in circulating myeloid progenitor cells in man

  1980cited by this paper
• Evidence for stem cells in the peripheral blood of mice.

  1962cited by this paper

• Rora Regulates Hematopoietic Stem Cell Phenotypes and Progression of Chronic Myelogenous Leukemia.

  2026cites this paper
• Squishing, squeezing and stretching age hematopoietic stem cells

  2026cites this paper
• Neuro‐Immune Crosstalk: Molecular Mechanisms, Biological Functions, Diseases, and Therapeutic Targets

  2026cites this paper
• Stromal-Derived Factor-1 (SDF-1/CXCL12) and Skin Wound Healing Research at the Intersection Between Regenerative Biology and Medicine

  2026cites this paper
• CD34-positive circulating cells quantification during follow-up in myeloproliferative neoplasms

  2026cites this paper
• Sepsis induces long-term reprogramming of human HSPCs and drives myeloid dysregulation in sepsis survivors

  2026cites this paper
• The Neuro-Bone Axis in Metastatic Progression: Innervation, Neuro-Immune-Osteoclast Crosstalk, and Therapeutic Opportunities.

  2026cites this paper
• Life‐Threatening Agranulocytosis Induced by Sinomenine Hydrochloride in Chronic Kidney Disease: A Case Report and Literature Review

  2026cites this paper
• Metabolism and metabolites regulating hematopoiesis.

  2025cites this paper
• Altered thrombopoiesis in spontaneously hypertensive rats

  2025cites this paper
• Circadian Light Hygiene Is Associated with Anemia Markers in Young Adults

  2025cites this paper
• Temporal Orchestration of Immunity: How Circadian Clocks Coordinate Immune Responses.

  2025cites this paper
• Macro-scale, scaffold-assisted model of the human bone marrow endosteal niche using hiPSC-vascularized osteoblastic organoids.

  2025cites this paper
• Understanding the intricacies of cellular mechanisms in remyelination: The role of circadian rhythm.

  2025cites this paper
• Integrated control of leukocyte compartments as a feature of adaptive physiology.

  2025cites this paper
• Evaluation of sleep quality and engraftment in patients undergoing mobilization and hematopoietic stem cell transplantation

  2025cites this paper
• The Sympathetic Nervous Influence on Hematopoiesis Up To Date.

  2025cites this paper
• GABA produced by multiple bone marrow cell types regulates hematopoietic stem and progenitor cells

  2025cites this paper
• Optimizing stem cell infusion timing in the prevention of acute graft-versus-host disease.

  2025cites this paper
• Circadian rhythm and immunity: decoding chrono-immunology using the model organism Drosophila melanogaster.

  2025cites this paper
• Connection and communication between the nervous and immune systems

  2025cites this paper
• Quantitative proteomics and phosphoproteomics reveal glucocorticoid stimulation of TLR and Rho GTPase signaling in neutrophil-like cells

  2025cites this paper
• Cancer Neuroscience: Decoding Neural Circuitry in Tumor Evolution for Targeted Therapy

  2025cites this paper
• Circadian Clock: A Regulator of Immunity in Autoimmune Diseases

  2025cites this paper
• GABA produced by multiple bone marrow cell types regulates hematopoietic stem and progenitor cells

  2025cites this paper
• Circulating plasma cells: from basic mechanisms to clinical applications

  2025cites this paper
• Circadian Control of Neutrophils Drives Collateral Perfusion and Stroke Outcome

  2025cites this paper
• Thymus ad astra, or spaceflight-induced thymic involution

  2025cites this paper
• Bone Marrow Niche Aging: Are Adipocytes Detrimental Cells in the Bone Marrow?

  2025influential citation
• Defective neutrophil clearance in JAK2V617F myeloproliferative neoplasms drives myelofibrosis via immune checkpoint CD24

  2025cites this paper
• Circadian clock–gated cell renewal controls time-dependent changes in taste sensitivity

  2025cites this paper
• Neural regulation of the thymus: past, current, and future perspectives

  2025cites this paper
• Bone Marrow Niche in Cardiometabolic Disease: Mechanisms and Therapeutic Potential.

  2025cites this paper
• Circadian rhythms in stem cells and their therapeutic potential

  2025cites this paper
• Diurnally‐Regulated Corticosterone and Melatonin Inversely Control Endotoxin‐Induced Acute Immune Responses

  2025cites this paper
• Bone marrow sympathetic neuropathy is a hallmark of hematopoietic malignancies and it involves severe ultrastructural damage

  2025cites this paper
• Immunometabolism in heart failure

  2025cites this paper
• The role of the extracellular matrix protein SPOCK2 for bone physiology and hematopoiesis.

  2025cites this paper
• The impact of aging on neutrophil functions and the contribution to periodontitis

  2025cites this paper
• Intra-bone marrow diversity of endothelial cells and its impact on hematopoietic stem cell development and maintenance.

  2025cites this paper
• Neuroimmunology and Sleep

  2025cites this paper
• SERCA-mediated endoplasmic reticulum stress facilitates hematopoietic stem cell mobilization

  2025cites this paper
• Serotonergic neurons regulate the Drosophila vascular niche to control immune stress hematopoiesis

  2025cites this paper
• Nervous system–gut microbiota–immune system axis: future directions for preventing tumor

  2025cites this paper
• The diverse roles of the circadian clock in cancer

  2025cites this paper
• Nanovaccines: Antigen selection, stabilization, adjuvantation, formulation, and evaluation

  2025cites this paper
• cKit Ligand (Stem Cell Factor)-Induced Immune Response via an Alternative Receptor in Human Cells

  2025cites this paper
• Impaired therapeutic efficacy of sleep-deprived bone marrow mesenchymal stem cells in the cerebellum of mouse cuprizone model of multiple sclerosis: stereological and motor behavioral evidence

  2025cites this paper
• Contemporary insights into neuroimmune interactions across development and aging

  2025cites this paper
• Cardiopulmonary neuro-immune reflex: From afferent stress signaling to peripheral myeloid memory.

  2025cites this paper
• Prognostic Role of Kidney Disease in Newly Diagnosed Acute Myeloid Leukemia Under Venetoclax-Based Low-Intensity Therapy

  2025cites this paper
• Association between muscle sympathetic nerve activity and red blood cell distribution width in adults

  2025cites this paper
• Transcriptional and epigenetic repression of hematopoietic stem cells underlies bone marrow failure after spinal cord injury

  2025cites this paper
• Stem Cells Run Like Clockwork for Stroke Therapeutics

  2025cites this paper
• Research progress on how mesenchymal stem cells regulate hematopoietic stem cell behavior

  2025cites this paper
• Investigating the effect of neuro-immune communication on immune responses in health and disease: Exploring immunological disorders.

  2025cites this paper
• The aging hematopoietic stem cell niche: a mini review.

  2025cites this paper
• Circadian Rhythms, Immune Regulation, and the Risk for Sepsis: Circadian Rhythms and Neonatal Care.

  2024cites this paper
• Evaluating diurnal rhythms of host responses to enteric norovirus infection in mouse models

  2024cites this paper
• Influences on the Hematopoietic Stem Cell Niche.

  2024cites this paper
• Neuro- and immuno-modulation mediated by the cardiac sympathetic nerve: a novel insight into the anti-ischemic efficacy of acupuncture.

  2024cites this paper
• Cellular crosstalk in the bone marrow niche

  2024cites this paper
• Neutrophils in toxicology: a forgotten field

  2024cites this paper
• Intermittent Fasting During Ramadan Increases the Absolute Number of Circulating Progenitor Stem Cells in Healthy Subjects

  2024cites this paper
• Development of VLA4 and CXCR4 Antagonists for the Mobilization of Hematopoietic Stem and Progenitor Cells

  2024cites this paper
• Regulation of the hematopoietic stem cell pool by C-Kit–associated trogocytosis

  2024cites this paper
• Adrenergic orchestration of immune cell dynamics in response to cardiac stress.

  2024cites this paper
• Sleep and Immune System Crosstalk: Implications for Inflammatory Homeostasis and Disease Pathogenesis

  2024cites this paper
• The hematopoietic niche and the autoreactive memory in autoimmune disorders.

  2024cites this paper
• Circadian disruption in cancer and regulation of cancer stem cells by circadian clock genes: An updated review.

  2024cites this paper
• Implications of Circadian Disruption on Intervertebral Disc Degeneration: The Mediating Role of Sympathetic Nervous System.

  2024cites this paper
• CHIP: a clonal odyssey of the bone marrow niche

  2024cites this paper
• Neuro-immune crosstalk in hematopoiesis, inflammation, and repair.

  2024cites this paper
• Investigation of Clock Genes Expression in G-CSFMobilized Individuals at Different Hours of the Day

  2024cites this paper
• Role of Neurotransmitters in Steady State Hematopoiesis, Aging, and Leukemia

  2024influential citation
• Targeting the bone marrow niche, moving towards leukemia eradication

  2024cites this paper
• Systemic and local regulation of hematopoietic homeostasis in health and disease

  2024influential citation
• Circadian control of tumor immunosuppression affects efficacy of immune checkpoint blockade

  2024cites this paper
• The specificities, influencing factors, and medical implications of bone circadian rhythms

  2024cites this paper
• Circadian-clock-controlled endocrine and cytokine signals regulate multipotential innate lymphoid cell progenitors in the bone marrow

  2024cites this paper
• Circadian rhythm regulates the function of immune cells and participates in the development of tumors

  2024cites this paper
• Bone marrow niches for hematopoietic stem cells

  2024cites this paper
• International Society for Cell and Gene Therapy Clinical Translation Committee recommendations on mesenchymal stromal cells in graft-versus-host disease: easy manufacturing is faced with standardizing and commercialization challenges

  2024cites this paper
• Complexities of modelling the bone marrow microenvironment to facilitate haematopoietic research.

  2024cites this paper
• Macrophages in cardiovascular diseases: molecular mechanisms and therapeutic targets

  2024cites this paper
• How aging influences the gut-bone marrow axis and alters hematopoietic stem cell regulation

  2024cites this paper
• Lipid mediators in neutrophil biology: inflammation, resolution and beyond

  2024cites this paper
• Hematopoietic Stem Cells as an Integrative Hub Linking Lifestyle to Cardiovascular Health

  2024cites this paper
• Remodeling of the bone marrow microenvironment during acute myeloid leukemia progression

  2024cites this paper
• Made to order: emergency myelopoiesis and demand-adapted innate immune cell production

  2024cites this paper
• A multistep computational approach reveals a neuro-mesenchymal cell population in the embryonic hematopoietic stem cell niche.

  2024cites this paper
• Circadian Effects on Vascular Immunopathologies

  2024cites this paper
• Extramedullary hematopoiesis in cancer

  2024cites this paper
• Semaphorins and the bone marrow microenvironment: New candidates that influence the hematopoietic system.

  2024cites this paper
• Circulating hematopoietic stem/progenitor cell subsets contribute to human hematopoietic homeostasis

  2024cites this paper
• Circadian disturbances by altering the light–dark cycle negatively affects hematopoietic function of bone marrow in mice

  2024cites this paper
• Interorgan rhythmicity as a feature of healthful metabolism.

  2024cites this paper
• Circadian Rhythms in Solid Organ Transplantation.

  2024cites this paper
• Stress-induced stenotic vascular remodeling via reduction of plasma omega-3 fatty acid metabolite 4-oxoDHA by noradrenaline

  2024cites this paper
• Circadian immunity from bench to bedside: a practical guide

  2024cites this paper