Gut–Brain Axis and Mood Disorder

Humans have over 100 trillion bacteria, highly abundant in the intestinal tract. Evidence suggests that intestinal microbiota is associated with the neuro-endocrine-immune pathways and can be associated with various mood disorders. This review summarizes findings from studies looking into neurobiochemical, neuroendocrine, and neuroimmune system mechanisms of the gut–brain axis to determine the relationship between intestinal microbiota and mood disorders. The effect of prebiotics, probiotics and antibiotics on mood disorders are also discussed, with the aim to propose some new therapeutic strategies for mood disorders.

• Publication year

  2018

• Venue

  Frontiers in Psychiatry

• Publication date

  2018-05-29

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.3389/fpsyt.2018.00223PMID 29896129PMCID 5987167
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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