The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Nature Neuroscience

• Publication date

  2012-01-29

• Fields of study

  Medicine, Psychology

• Identifiers
  DOI 10.1038/nn.3028PMID 22286176
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• De novo induction of amyloid-β deposition in vivo

  2013cited by this paper
• De novo induction of amyloid-β deposition in vivo

  2012cited by this paper
• Cognitive effects of cell-derived and synthetically derived Aβ oligomers.

  2011cited by this paper
• The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics

  2011cited by this paper
• P4‐316: Stabilization of neurotoxic Alzheimer amyloid‐beta oligomers by protein engineering

  2011cited by this paper
• Amyloid-β Annular Protofibrils Evade Fibrillar Fate in Alzheimer Disease Brain*♦

  2011cited by this paper
• High ability of apolipoprotein E4 to stabilize amyloid‐β peptide oligomers, the pathological entities responsible for Alzheimer's disease

  2011cited by this paper
• Two Distinct Amyloid β-Protein (Aβ) Assembly Pathways Leading to Oligomers and Fibrils Identified by Combined Fluorescence Correlation Spectroscopy, Morphology, and Toxicity Analyses*

  2011cited by this paper
• Characteristics of amyloid-related oligomers revealed by crystal structures of macrocyclic β-sheet mimics.

  2011cited by this paper
• A monoclonal antibody against synthetic Aβ dimer assemblies neutralizes brain‐derived synaptic plasticity‐disrupting Aβ

  2011cited by this paper
• Tau Protein Is Required for Amyloid β-Induced Impairment of Hippocampal Long-Term Potentiation

  2011cited by this paper
• Aβ1–42 inhibition of LTP is mediated by a signaling pathway involving caspase-3, Akt1 and GSK-3β

  2011cited by this paper
• Soluble amyloid β-protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration

  2011cited by this paper
• Human apoE Isoforms Differentially Regulate Brain Amyloid-β Peptide Clearance

  2011influential reference
• Peripherally applied Abeta-containing inoculates induce cerebral beta-amyloidosis

  2011cited by this paper
• State of aggregation

  2011cited by this paper
• Amyloid-β Forms Fibrils by Nucleated Conformational Conversion of Oligomers

  2011influential reference
• Extracellular phosphorylation of the amyloid β‐peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease

  2011cited by this paper
• Ion mobility-mass spectrometry reveals a conformational conversion from random assembly to beta-sheet in amyloid fibril formation

  2010cited by this paper
• Stabilization of neurotoxic Alzheimer amyloid-β oligomers by protein engineering

  2010cited by this paper
• Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models.

  2010cited by this paper
• Amyloid β-Protein Dimers Rapidly Form Stable Synaptotoxic Protofibrils

  2010cited by this paper
• A Critical Reappraisal

  2010influential reference
• Blood-Borne Amyloid-β Dimer Correlates with Clinical Markers of Alzheimer's Disease

  2010cited by this paper
• Proteases and Proteolysis in Alzheimer Disease: A Multifactorial View on the Disease Process

  2010cited by this paper
• A causative link between the structure of aberrant protein oligomers and their toxicity.

  2010influential reference
• The Monomer State of Beta-Amyloid: Where the Alzheimer's Disease Protein Meets Physiology

  2010cited by this paper
• Amyloid-β-Derived Diffusible Ligands Cause Impaired Axonal Transport of Mitochondria in Neurons

  2010cited by this paper
• Aβ Oligomers Cause Localized Ca2+ Elevation, Missorting of Endogenous Tau into Dendrites, Tau Phosphorylation, and Destruction of Microtubules and Spines

  2010cited by this paper
• Distinct cerebrospinal fluid amyloid β peptide signatures in sporadic and PSEN1 A431E-associated familial Alzheimer's disease

  2010cited by this paper
• Anti-ADDL antibodies differentially block oligomer binding to hippocampal neurons.

  2010cited by this paper
• Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio

  2010cited by this paper
• Peripherally Applied Aβ-Containing Inoculates Induce Cerebral β-Amyloidosis

  2010cited by this paper
• Amyloid beta induces the morphological neurodegenerative triad of spine loss, dendritic simplification, and neuritic dystrophies through calcineurin activation.

  2010influential reference
• Proteases and proteolysis in Alzheimer disease: a multifactorial view on the disease process.

  2010cited by this paper
• Generation and Therapeutic Efficacy of Highly Oligomer-Specific β-Amyloid Antibodies

  2010cited by this paper
• The presence of sodium dodecyl sulphate-stable Abeta dimers is strongly associated with Alzheimer-type dementia.

  2010cited by this paper
• An amyloid-beta protofibril-selective antibody prevents amyloid formation in a mouse model of Alzheimer's disease.

  2009cited by this paper
• NMDA receptor–dependent signaling pathways that underlie amyloid β‐protein disruption of LTP in the hippocampus

  2009cited by this paper
• Direct in vivo intracellular selection of conformation-sensitive antibody domains targeting Alzheimer's amyloid-beta oligomers.

  2009cited by this paper
• Intracellular amyloid formation in muscle cells of Aβ-transgenic Caenorhabditis elegans: determinants and physiological role in copper detoxification

  2009cited by this paper
• Cellular Prion Protein Mediates Impairment of Synaptic Plasticity by Amyloid-β Oligomers

  2009cited by this paper
• Biochemical and immunohistochemical analysis of an Alzheimer's disease mouse model reveals the presence of multiple cerebral Abeta assembly forms throughout life.

  2009influential reference
• Multimodal techniques for diagnosis and prognosis of Alzheimer's disease

  2009influential reference
• The amyloid hypothesis for Alzheimer’s disease: a critical reappraisal

  2009cited by this paper
• Single-domain antibodies recognize selectively small oligomeric forms of amyloid beta, prevent Abeta-induced neurotoxicity and inhibit fibril formation.

  2009cited by this paper
• Faculty Opinions recommendation of Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers.

  2009cited by this paper
• Amyloid seeds formed by cellular uptake, concentration, and aggregation of the amyloid-beta peptide

  2009cited by this paper
• Structure–neurotoxicity relationships of amyloid β-protein oligomers

  2009cited by this paper
• Prions: protein aggregation and infectious diseases.

  2009cited by this paper
• G Protein–Coupled Receptors, Cholinergic Dysfunction, and Aβ Toxicity in Alzheimer’s Disease

  2009cited by this paper
• The Amyloid Hypothesis of Alzheimer ’ s Disease : Progress and Problems on the Road to Therapeutics

  2009cited by this paper
• Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake.

  2009cited by this paper
• Amyloid Goes Global

  2009influential reference
• Pyroglutamate formation influences solubility and amyloidogenicity of amyloid peptides.

  2009cited by this paper
• Characterisation of two antibodies to oligomeric Abeta and their use in ELISAs on human brain tissue homogenates.

  2009cited by this paper
• Isolation and Characterization of Patient-derived, Toxic, High Mass Amyloid β-Protein (Aβ) Assembly from Alzheimer Disease Brains*

  2009cited by this paper
• A new amyloid β variant favoring oligomerization in Alzheimer's‐type dementia

  2008cited by this paper
• Anti-oligomeric Abeta single-chain variable domain antibody blocks Abeta-induced toxicity against human neuroblastoma cells.

  2008cited by this paper
• Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

  2008influential reference
• Peripheral Aβ subspecies as risk biomarkers of Alzheimer's disease

  2008cited by this paper
• Alzheimer's disease-type neuronal tau hyperphosphorylation induced by A beta oligomers.

  2008cited by this paper
• Alzheimer's disease-type neuronal tau hyperphosphorylation induced by Aβ oligomers

  2008cited by this paper
• Transglutaminase Induces Protofibril-like Amyloid β-Protein Assemblies That Are Protease-resistant and Inhibit Long-term Potentiation*

  2008influential reference
• Directed selection of a conformational antibody domain that prevents mature amyloid fibril formation by stabilizing Aβ protofibrils

  2007cited by this paper
• Sensitive ELISA detection of amyloid-beta protofibrils in biological samples.

  2007cited by this paper
• Sensitive ELISA detection of amyloid‐β protofibrils in biological samples

  2007cited by this paper
• The presenilin hypothesis of Alzheimer's disease: Evidence for a loss-of-function pathogenic mechanism

  2007cited by this paper
• Molecular basis for passive immunotherapy of Alzheimer's disease

  2007cited by this paper
• A General Model of Prion Strains and Their Pathogenicity

  2007cited by this paper
• Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers

  2007cited by this paper
• Monoclonal antibodies that target pathological assemblies of Aβ

  2007cited by this paper
• Conformation-sensitive Antibodies against Alzheimer Amyloid-β by Immunization with a Thioredoxin-constrained B-cell Epitope Peptide*

  2007cited by this paper
• Targeting Amyloid-β Peptide (Aβ) Oligomers by Passive Immunization with a Conformation-selective Monoclonal Antibody Improves Learning and Memory in Aβ Precursor Protein (APP) Transgenic Mice*

  2006cited by this paper
• Amyloid β‐protein monomer structure: A computational and experimental study

  2006cited by this paper
• Different Conformations of Amyloid β Induce Neurotoxicity by Distinct Mechanisms in Human Cortical Neurons

  2006cited by this paper
• Solution State Characterization of Amyloid β-Derived Diffusible Ligands

  2006cited by this paper
• A specific amyloid-beta protein assembly in the brain impairs memory.

  2006cited by this paper
• Exogenous Induction of Cerebral ß-Amyloidogenesis Is Governed by Agent and Host

  2006cited by this paper
• Solution state characterization of amyloid beta-derived diffusible ligands.

  2006cited by this paper
• A specific amyloid-β protein assembly in the brain impairs memory

  2006cited by this paper
• Copper-mediated Amyloid-β Toxicity Is Associated with an Intermolecular Histidine Bridge*

  2006cited by this paper
• Effects of secreted oligomers of amyloid β‐protein on hippocampal synaptic plasticity: a potent role for trimers

  2006cited by this paper
• Neurotoxic protein oligomers — what you see is not always what you get

  2005influential reference
• Calcium Dysregulation and Membrane Disruption as a Ubiquitous Neurotoxic Mechanism of Soluble Amyloid Oligomers*♦

  2005cited by this paper
• Natural oligomers of the amyloid-β protein specifically disrupt cognitive function

  2005cited by this paper
• Nucleation-Dependent Polymerization Is an Essential Component of Amyloid-Mediated Neuronal Cell Death

  2005cited by this paper
• What is the role of protein aggregation in neurodegeneration?

  2005cited by this paper
• Globular amyloid beta-peptide oligomer - a homogenous and stable neuropathological protein in Alzheimer's disease.

  2005cited by this paper
• Self-Propagating, Molecular-Level Polymorphism in Alzheimer's ß-Amyloid Fibrils

  2005cited by this paper
• Self-propagating, molecular-level polymorphism in Alzheimer's beta-amyloid fibrils.

  2005cited by this paper
• Globular amyloid β‐peptide1−42 oligomer − a homogenous and stable neuropathological protein in Alzheimer's disease

  2005cited by this paper
• Common Structure of Soluble Amyloid Oligomers Implies Common Mechanism of Pathogenesis

  2003cited by this paper
• The regulation of glucose metabolism by HIF-1 mediates a neuroprotective response to amyloid beta peptide.

  2003cited by this paper
• Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders.

  2003cited by this paper
• Spherical aggregates of beta-amyloid (amylospheroid) show high neurotoxicity and activate tau protein kinase I/glycogen synthase kinase-3beta.

  2003cited by this paper
• Spherical aggregates of β-amyloid (amylospheroid) show high neurotoxicity and activate tau protein kinase I/glycogen synthase kinase-3β

  2003cited by this paper
• Conformational Abs recognizing a generic amyloid fibril epitope

  2002cited by this paper
• Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo

  2002influential reference
• The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics

  2002cited by this paper

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