Protective Effects of Vitamin C (Ascorbic Acid) in Lead Acetate Exposed Diabetic Male Rats: Evaluation of Blood Biochemical Parameters and Testicular Histopathology

Bu calismanin amaci diyabetik erkek sicanlarda kan parametrelerinin olculmesi ve testisin histopatolojisinin calisilmasi ile vitamin C’nin kursun toksisitesine karsi koruyucu etkisini incelemektir. Wistar sicanlar (42) rastgele 7 gruba ayrilmistir I) saglikli; II) sadece kursun asetat ile beslenenler; III) sadece vitamin C uygulananlar; IV) diyabetik; V) vitamin C uygulanan diyabetik sicanlar; VI) kursun asetat verilen diyabetik sicanlar ve VII) kursun asetat ve vitamin C uygulanan diyabetik sicanlar. Diyabetik ve kursun verilen gruplarin kontrol gruplara kiyasla daha yuksek glukoz, kolesterol, LDL, trigliseritler ve daha dusuk insulin ve HDL konsantrasyonuna sahip olduklari tespit edilmistir. Vitamin C uygulamasi kanda glukoz, kolesterol, LDL ve trigliserit duzeylerini dusurdugu HDL konsantrasyonunu ise arttirdigi saptanmistir. Sonuc olarak diyabetik farelerde vitamin C’nin antioksidan ozelligi, kursun asetatin toksik seviyelerinde oksidatif stres komplikasyonlarini azaltmasina neden olmustur.

• Publication year

  2015

• Venue

  Unknown venue

• Publication date

  2015-01-05

• Fields of study

  Not labeled

• Identifiers
  DOI 10.16988/IUVFD.2015.90715
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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