Predictive testing for Huntington's disease with use of a linked DNA marker.

No abstract is available for this paper.

• Publication year

  1988

• Venue

  New England Journal of Medicine

• Publication date

  1988-03-03

• Fields of study

  Medicine

• Identifiers
  DOI 10.1056/NEJM198803033180903PMID 2893260
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Attitudes of persons at risk for Huntington disease toward predictive testing.

  1987cited by this paper
• Testing for the Huntington gene: a right to know, a right not to know, or a duty to know.

  1987cited by this paper
• First-trimester prenatal diagnosis for Huntington's disease with DNA probes.

  1987cited by this paper
• Homozygotes for Huntington's disease

  1987cited by this paper
• Intended use of predictive testing by those at risk for Huntington disease.

  1987cited by this paper
• A DNA segment encoding two genes very tightly linked to Huntington's disease.

  1987cited by this paper
• At-risk persons' attitudes toward presymptomatic and prenatal testing of Huntington disease in Michigan.

  1987cited by this paper
• Presymptomatic testing for Huntington chorea: guidelines for moral and social accountability.

  1987cited by this paper
• Genetic linkage in neurologic diseases.

  1987cited by this paper
• The decision to be tested for Huntington's disease.

  1987cited by this paper
• Attitudes toward presymptomatic testing in Huntington disease.

  1987cited by this paper
• Presymptomatic testing for Huntington chorea: ethical and legal issues.

  1987cited by this paper
• Exclusion testing for Huntington's disease in pregnancy with a closely linked DNA marker.

  1987cited by this paper
• Genetic screening raises questions for employers and insurers.

  1986cited by this paper
• Huntington's disease. Pathogenesis and management.

  1986cited by this paper
• Legal problems of Huntington's chorea tests

  1986cited by this paper
• Ethics of predictive testing for Huntington's chorea: the need for more information.

  1986cited by this paper
• Suicide and attempted suicide in Huntington disease: implications for preclinical testing of persons at risk.

  1986cited by this paper
• Presymptomatic testing for Huntington's disease.

  1985cited by this paper
• A DNA polymorphism for Huntington's disease marks the future.

  1985cited by this paper
• Multilocus linkage analysis in humans: detection of linkage and estimation of recombination.

  1985cited by this paper
• A genetic model for age at onset in Huntington disease.

  1985cited by this paper
• Genetic prediction and family structure in Huntington's chorea.

  1985cited by this paper
• Genomic sequencing.

  1984cited by this paper
• Huntington's disease

  1984cited by this paper
• Potential impact of a predictive test on the gene frequency of Huntington disease.

  1984cited by this paper
• "A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity". Addendum.

  1984cited by this paper
• Huntington disease: Estimation of heterozygote status using linked genetic markers

  1984cited by this paper
• Huntington disease: genetics and epidemiology.

  1984cited by this paper
• SCL-90-R, Administration, Scoring, and Procedures Manual-II for the R(evised) Version and Other Instruments of the Psychopathology Rating Scale Series

  1983cited by this paper
• Effect of genetic counselling on the prevalence of Huntington's chorea.

  1983cited by this paper
• A polymorphic DNA marker genetically linked to Huntington's disease

  1983cited by this paper
• A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity.

  1983cited by this paper
• Huntington’s Chorea

  1981cited by this paper
• Decline in the predicted incidence of Huntington's chorea associated with systematic genetic counselling and family support.

  1981cited by this paper
• Ethics of provocative test for Huntington's disease.

  1981cited by this paper
• Precise localization of human beta-globin gene complex on chromosome 11.

  1979cited by this paper
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  1978cited by this paper
• Detection of specific sequences among DNA fragments separated by gel electrophoresis.

  1975cited by this paper
• Letter: Myoclonus, methysergide, and serotonin.

  1974cited by this paper
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  1974cited by this paper
• Assessment of depression: the depression inventory.

  1974cited by this paper

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  2022cites this paper
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  2021cites this paper
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  2018cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
• 22 Years of predictive testing for Huntington’s disease: the experience of the UK Huntington’s Prediction Consortium

  2016cites this paper
• Years of predictive testing for Huntington ’ s disease : the experience of the UK Huntington ’ s Prediction Consortium

  2016cites this paper
• Genetic counselling implications for intermediate allele predictive test results for Huntington disease

  2012cites this paper
• Chapter 14 – Huntington disease

  2011cites this paper
• IMPACTO PSICOSOCIAL DE PRUEBAS GENÉTICAS PREDICTIVAS EN ENFERMEDADES NEURODEGENERATIVAS DE INICIO TARDÍO (ATAXIA ESPINOCEREBELOSA TIPO 2 Y POLINEUROPATÍA AMILOIDÓTICA FAMILIAR ATTRV30M)

  2011cites this paper
• Generation after generation: Exploring the psychological impact of providing genetic services through a cascading approach

  2010cites this paper
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  2009cites this paper
• Presymptomatic Diagnosis in Huntington's Disease: The Mexican Experience

  2009cites this paper
• Mental health and quality of life after genetic testing for Huntington disease: A long‐term effect study in Germany

  2008cites this paper
• To know or not to know: a review of behaviour and suicidal ideation in preclinical Huntington's disease.

  2007cites this paper
• Genetic criteria for Huntington's disease pathogenesis.

  2007cites this paper
• Risk Reduction and Health Promotion Behaviors Following Genetic Testing for Adult-Onset Disorders

  2007cites this paper
• The Perceived Advantages and Disadvantages of Presymptomatic Testing for Machado-Joseph Disease: Development of a New Self-Response Inventory

  2006cites this paper
• ASPECTOS PSICOSSOCIAIS DA MEDICINA PREDITIVA: REVISÃO DA LITERATURA SOBRE TESTES DE RISCOS GENÉTICOS

  2005cites this paper
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  2005cites this paper
• ESCALA DE ACEITAÇÃO DO TESTE PRÉ-SINTOMÁTICO: ESTUDO DE VALIDAÇÃO COM UMA AMOSTRA DE PESSOAS EM RISCO PARA A DOENÇA DE MACHADO-JOSEPH

  2005cites this paper
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  2005cites this paper
• Eine epidemiologische Studie im süddeutschen Raum

  2004cites this paper
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  2004cites this paper
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  2004cites this paper
• Psychologic distress after disclosure of genetic test results regarding hereditary nonpolyposis colorectal carcinoma

  2004cites this paper
• Psychological consequences and predictors of adverse events in the first 5 years after predictive testing for Huntington's disease

  2003cites this paper
• Stories in Decisions: How At-Risk Individuals Decide to Request Predictive Testing for Huntington Disease

  2003cites this paper
• Predictive, pre‐natal and diagnostic genetic testing for Huntington's disease: the experience in Canada from 1987 to 2000

  2003influential citation
• Genetic Exceptionalism in Medicine: Clarifying the Differences between Genetic and Nongenetic Tests

  2003cites this paper
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  2003cites this paper
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  2003cites this paper
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  2002cites this paper
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  2002cites this paper
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  2001cites this paper
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  2000cites this paper
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  1999cites this paper
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  1999cites this paper
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  1999cites this paper
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  1999influential citation
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  1999cites this paper
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  1998influential citation
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  1998cites this paper
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  1998cites this paper
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  1997cites this paper
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  1997cites this paper
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  1997cites this paper
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  1997cites this paper
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  1997cites this paper
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  1997cites this paper
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  1997cites this paper
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  1997cites this paper
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  1996cites this paper
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  1996cites this paper
• Issues in genetic testing for susceptibility to alcoholism: lessons from Alzheimer's disease and Huntington's disease.

  1996cites this paper
• [Huntington chorea. Molecular genetic principles, mutation detection and predictive diagnosis].

  1996cites this paper
• Genetic tests: evolving policy questions

  1996cites this paper
• Psychosocial aspects of neurological disorders: Implications for research in neuropsychology

  1996cites this paper
• Chapter 15 DNA probes in human diseases

  1996cites this paper
• Emotional and functional impact of DNA testing on patients with symptoms of Huntington's disease.

  1995cites this paper
• Presymptomatic Testing for Genetic Diseases of Later Life

  1995cites this paper
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  1995cites this paper
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  1995cites this paper
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  1994cites this paper
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  1994cites this paper
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  1994cites this paper
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  1994cites this paper
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  1994cites this paper
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  1994cites this paper
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  1994cites this paper
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  1994cites this paper
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  1993cites this paper
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  1993cites this paper
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  1993cites this paper
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  1993cites this paper
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• [Genetic markers in neuropsychiatric disorders: genetic cartography and diagnostic and therapeutic explorations (II)].

  1993cites this paper
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  1993cites this paper
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  1993cites this paper
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  1993cites this paper
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  1993cites this paper
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  1992cites this paper
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  1992cites this paper
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  1992cites this paper