Synthesizing life

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Nature

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Materials Science, Environmental Science

• Identifiers
  DOI 10.1038/35053176PMID 11201752
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Kinetic framework for ligation by an efficient RNA ligase ribozyme.

  2000cited by this paper
• Constructing an RNA world.

  1999cited by this paper
• Global transposon mutagenesis and a minimal Mycoplasma genome.

  1999cited by this paper
• RNAs that bind and change the permeability of phospholipid membranes.

  1999cited by this paper
• A Fission-Fusion Origin for Life

  1998cited by this paper
• About Various Definitions of Life

  1998cited by this paper
• Ribozymes: aiming at RNA replication and protein synthesis.

  1996cited by this paper
• Effects of submicellar bile salt concentrations on biological membrane permeability to low molecular weight non-ionic solutes.

  1996cited by this paper
• RNA-catalysed RNA polymerization using nucleoside triphosphates

  1996cited by this paper
• Structurally complex and highly active RNA ligases derived from random RNA sequences.

  1995cited by this paper
• Polymerase chain reaction in liposomes.

  1995cited by this paper
• The secondary structure and sequence optimization of an RNA ligase ribozyme.

  1995cited by this paper
• Production of RNA by a polymerase protein encapsulated within phospholipid vesicles

  1994cited by this paper
• Isolation of new ribozymes from a large pool of random sequences [see comment].

  1993cited by this paper
• Selection of a ribozyme that functions as a superior template in a self-copying reaction.

  1992cited by this paper
• The rise and fall of the RNA world.

  1991cited by this paper
• A multisubunit ribozyme that is a catalyst of and template for complementary strand RNA synthesis.

  1991cited by this paper
• RNA-catalysed synthesis of complementary-strand RNA

  1989cited by this paper
• Partition behavior of a nonionic detergent, octyl glucoside, between membrane and water phases, and its effect on membrane permeability.

  1989cited by this paper
• pH-dependent fusion of phosphatidylcholine small vesicles. Induction by a synthetic amphipathic peptide.

  1988cited by this paper
• RNA world

  1987cited by this paper
• Evolution of the RNA coliphages: the role of secondary structures during RNA replication.

  1987cited by this paper
• H+- and Ca2+-induced fusion and destabilization of liposomes.

  1985cited by this paper
• Studies on the mechanism of membrane fusion: kinetics of calcium ion induced fusion of phosphatidylserine vesicles followed by a new assay for mixing of aqueous vesicle contents.

  1980cited by this paper
• The role of calcium in fusion of artificial vesicles.

  1978cited by this paper

• Harnessing Dynamic Self‐Assembly to Accelerate Chemical Reactions

  2026cites this paper
• Deep-Sea Hydrothermal Vent and Impact-Generated Hydrothermal Vent Systems: Insights into the Origin of Life

  2026cites this paper
• Organocatalyzed bottom-up formation of protocells

  2026cites this paper
• Phasentrennung von Nukleinsäuren: Mechanismen, Eigenschaften und Anwendungen

  2026cites this paper
• From Searching for Extraterrestrial Biosignatures to Exploring the Origins of Life: A Prebiotic Chemistry Perspective

  2026cites this paper
• G-quadruplexes self-assembled from nucleotide monomers as stable prepolymer scaffolds in aqueous environments

  2026cites this paper
• Evolution of pre-genetic semantic information in protocells under variable inheritance fidelity

  2026cites this paper
• Polymeric emulsifier and diatom‐inspired membrane synergistically locate enzymes for interfacial cascade reactions

  2026cites this paper
• Pier Luigi Luisi (1938–2025)

  2026cites this paper
• From Equilibrium to Emergence: The Physical Foundations of Chemical Order – A Conceptual Framework Linking Thermodynamics, Quantum Mechanics and Systems Chemistry

  2026cites this paper
• De novo emergence of metabolically active protocells

  2026cites this paper
• Template-Based Catalysis and the Emergence of Collectively Autocatalytic Systems.

  2026cites this paper
• Advances in artificial cells capable of metabolic mimicry: from fundamentals to applications.

  2026cites this paper
• Phase Separation of Nucleic Acids: Mechanisms, Properties, and Applications.

  2026cites this paper
• Life on Mars? The physiological perspective.

  2026cites this paper
• Surface‐Driven Protocell Formation in Geologically Relevant Early Earth Environment

  2026cites this paper
• Hot Mineral Water as a Medium for Molecular Hydrogen Reactions in the Primordial Hydrosphere for the Origin of Life

  2025cites this paper
• Advances in Intelligent Design and Optimization Methods for Nucleic Acid Sequences

  2025cites this paper
• Construction of a De Novo Nucleotide Biosynthesis Pathway in Artificial Cells for RNA Transcription.

  2025cites this paper
• Development of Dipeptide-Based Liquid Droplets and Fibrils as Enzyme-Mimics.

  2025cites this paper
• Positioning Formation and Controllable Fabrication of Lipid Vesicles Using Patterned Substrates

  2025cites this paper
• Membraneless protocell confined by a heat flow

  2025cites this paper
• On the Evolution of Biomolecular Condensates: From Prebiotic Origins to Subcellular Diversity.

  2025cites this paper
• Living dynamic polymeric materials.

  2025cites this paper
• Autonomous ribosome biogenesis in vitro

  2025cites this paper
• What ‘Has Life Potentially’?

  2025cites this paper
• Thermodynamics of Morphogenesis: Beading and Branching Pattern Formation in Diffusion-Driven Salt Finger Plumes

  2025cites this paper
• Medical and Nonmedical Applications of Synthetic Transmembrane Anion Transporters

  2025cites this paper
• Accelerated design of Escherichia coli reduced genomes using a whole-cell model and machine learning

  2025cites this paper
• Challenge-Based Funding to Spark Origins Breakthroughs

  2025cites this paper
• Emergent Chemical Reactivity and Complexity of RNA Condensates

  2025cites this paper
• The non-canonical nucleotides and prebiotic evolution

  2025cites this paper
• Compositional selection of phospholipid compartments in icy environments drives the inheritance of encapsulated genetic information

  2025cites this paper
• Characterizing mixed single chain amphiphile-based coacervates as a robust protocell system

  2025cites this paper
• Phase-separated lipid vesicles: continuum modeling, simulation, and validation

  2025cites this paper
• Renormalized mechanics and stochastic thermodynamics of growing vesicles

  2025cites this paper
• Chemiosmotic ATP synthesis by minimal protocells

  2025cites this paper
• False-vacuum decay and flaws in Frampton's model of the origin of life

  2025cites this paper
• Cell membranes and the organization of biological information

  2025cites this paper
• Glassy dynamics of model complex coacervate films with variable interaction strength quantified by the critical salt concentration.

  2025cites this paper
• Synthetic nucleic-acid droplets: a bioprogramming platform for designer microliquids

  2025cites this paper
• Permeability selection of biologically relevant membranes matches the stereochemistry of life on Earth

  2025cites this paper
• Serotonergic Mechanisms in Proteinoid-Based Protocells

  2025cites this paper
• Constructal thermodynamics and its semantic ontology in autopoietic, digital, and computational architectural and urban space open systems

  2025cites this paper
• Responsive DNA artificial cells for contact and behavior regulation of mammalian cells

  2025cites this paper
• Critical bifurcations in deformable membrane necks under inhomogeneous curvature: constriction frustration vs. abscissional elongation

  2025cites this paper
• Genealogical Searching

  2025cites this paper
• An Integrative View on Multiple "Lipid Divide" Events as Hallmarks of Distinct Evolutionary Transitions.

  2025cites this paper
• Direct photochemical control of imine exchange reactions

  2025cites this paper
• Photochemical synthesis of natural lipids in artificial and living cells

  2025cites this paper
• Tuning Covalent Organic Frameworks for Nucleic Acid Loading: Toward Creating a Hierarchical Artificial Cell.

  2025cites this paper
• Bistable Functions and Signaling Motifs in Systems Chemistry: Taking the Next Step Toward Synthetic Cells

  2025cites this paper
• From experimental clues to theoretical modeling: Evolution associated with the membrane-takeover at an early stage of life

  2025cites this paper
• Construction of the reduced nicotinamide adenine dinucleotide salvage pathway in artificial cells and its application in amino acid synthesis

  2025cites this paper
• Optimizing (Bio) Catalysis with Liquid‐Liquid Phase Separation Systems

  2025cites this paper
• Compositional selection of phospholipid compartments in icy environments drives the enrichment of encapsulated genetic information

  2025cites this paper
• Microstructures as Models for Origin of Life in Hot Water: Hydrogen-Assisted Self-Assembly of Glycine and Alanine Zwitterions

  2025cites this paper
• The secret life of RNA and lipids

  2025cites this paper
• Advances in Multicompartment Synthetic Protocells: from Design Strategies to Biomedical Application.

  2025cites this paper
• Coacervates meet the RNP-world: liquid-liquid phase separation and the emergence of biological compartmentalization

  2025cites this paper
• Potentially Prebiotic Isocyanide Activation Chemistry Drives RNA Assembly via both Nonenzymatic and Ribozymecatalyzed Ligation

  2025cites this paper
• A proposed mechanism for the formation of protocell-like structures on Titan

  2025cites this paper
• Anion-π interaction-induced phase separation as a prebiotic pathway to oxygenation.

  2025cites this paper
• Spontaneous Fusion of Aqueous Two‐Phase Droplets: Effect of Coexisting Phospholipids on Stability

  2025cites this paper
• Coacervate Vesicles as Adaptive Platforms for Synthetic Biology and Smart Materials

  2025cites this paper
• Engineering of DNA nanostructure-based artificial cells for biosensing applications

  2025cites this paper
• Dynamical interactions among protocell populations: Implications for membrane-mediated chemical evolution.

  2025cites this paper
• Reconstituting alternative life using the test-bed of cell-free systems

  2025cites this paper
• Potentially prebiotic isocyanide activation chemistry drives RNA assembly

  2025cites this paper
• Who Decides What Is Prebiotically Plausible? The Risks of Premature Constraints in Origin-of-Life Research

  2025cites this paper
• Protocells Either Synchronize or Starve

  2025cites this paper
• Construction of Artificial Cells with Urea Cycle Pathway for Ammonia Detoxification.

  2025cites this paper
• Minimalist Molecules Drive Liquid-Liquid Phase Separation to Modularly Assemble Functional Coacervate Protocells.

  2025cites this paper
• Polymeric Artificial Cells: from Interfacial Membranization to Cytomimetic Architecture Engineering.

  2025cites this paper
• Interfacial energy-mediated bulk transport across artificial cell membranes

  2024cites this paper
• Self-growing protocell models in aqueous two-phase system induced by internal DNA replication reaction

  2024cites this paper
• Protocell Effects on RNA Folding, Function, and Evolution

  2024cites this paper
• Vesicle-like Nanocapsules Formed by Self-Assembly of Peptides with Oligoproline and -Leucine.

  2024cites this paper
• Compartmentalization as a ubiquitous feature of life: from origins of life to biomimetics

  2024cites this paper
• Protocells Featuring Membrane-Bound and Dynamic Membraneless Organelles.

  2024cites this paper
• Fitness Landscapes and Evolution of Catalytic RNA.

  2024cites this paper
• Optimizing in vitro expression balance of central dogma-related genes using parallel reaction monitoring.

  2024cites this paper
• Probing and evaluating transmembrane chloride ion transport in double walled trifluorophenyl/phthalimide extended calix[4]pyrrole-based supramolecular receptors.

  2024cites this paper
• Unveiling structural and energetic characterization of the emissive RNA alphabet anchored in the methylthieno[3,4-d]pyrimidine heterocycle core.

  2024cites this paper
• Gas-Responsive and Gas-Releasing Polymer Assemblies.

  2024cites this paper
• DNA-empowered synthetic cells as minimalistic life forms

  2024cites this paper
• Intermedial semiotics in the age of artificial intelligence. Challenges and opportunities for the arts

  2024cites this paper
• Autocatalysis, Autopoiesis, and the Opportunity Cost of Individuality

  2024cites this paper
• Prebiotic membrane structures mimic the morphology of alleged early traces of life on Earth

  2024cites this paper
• Circular at the very beginning: on the initial genomes in the RNA world

  2024cites this paper
• Apoptosis-Inducing Activity of a 2-Hydroxyphenyl Benzamide-Based Self-Assembled Anion Channel.

  2024cites this paper
• Reconfigurable nanomaterials folded from multicomponent chains of DNA origami voxels

  2024cites this paper
• Spontaneous Emergence of Lipid Vesicles in a Coacervate-Based Compartmentalized System.

  2024cites this paper
• Dynamic satellite–parent liposome networks for quantitative microreactions

  2024cites this paper
• The Evolutionary Transition of the RNA World to Obcells to Cellular-Based Life

  2024cites this paper
• Biomimetic Materials to Fabricate Artificial Cells.

  2024cites this paper
• Environmental constraints on the origin of life based on membrane formation: the role of salinity

  2024cites this paper
• Catalytic peptide-based coacervates for enhanced function through structural organization and substrate specificity

  2024cites this paper
• Shadow electrochemiluminescence imaging of giant liposomes opening at polarized electrodes.

  2024cites this paper
• Protocells by spontaneous reaction of cysteine with short-chain thioesters

  2024cites this paper