Quantitative sensory testing in the German Research Network on Neuropathic Pain (DFNS): Standardized protocol and reference values

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Pain

• Publication date

  2006-08-01

• Fields of study

  Medicine, Psychology

• Identifiers
  DOI 10.1016/j.pain.2006.01.041PMID 16697110
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Quantitative sensory testing: a comprehensive protocol for clinical trials

  2006influential reference
• Dynamic mechanical allodynia: On the relationship between temporo‐spatial stimulus parameters and evoked pain in patients with peripheral neuropathy

  2005cited by this paper
• Financial Liberalisations in Latin America in the 1990s: A Reassessment

  2005cited by this paper
• Human surrogate models of neuropathic pain

  2005cited by this paper
• Use of the Rydel—Seiffer graduated tuning fork in the assessment of vibration threshold in postherpetic neuralgia patients and healthy controls

  2005cited by this paper
• Age effects on pain thresholds, temporal summation and spatial summation of heat and pressure pain

  2005cited by this paper
• Hyperalgesia : molecular mechanisms and clinical implications

  2004cited by this paper
• EFNS guidelines on neuropathic pain assessment

  2004cited by this paper
• Topical menthol--a human model for cold pain by activation and sensitization of C nociceptors.

  2004cited by this paper
• Advances in neuropathic pain: diagnosis, mechanisms, and treatment recommendations.

  2003cited by this paper
• Gender differences in pressure pain threshold in healthy humans

  2003cited by this paper
• Quantitative sensory testing Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology

  2003cited by this paper
• Clinical usefulness of laser-evoked potentials.

  2003cited by this paper
• Gender and laterality differences in thermosensation throughout the perceptible range

  2003cited by this paper
• Quantitative sensory testing

  2003cited by this paper
• Quantitative Sensory Testing and Human Surgery: Effects of Analgesic Management on Postoperative Neuroplasticity

  2003cited by this paper
• Translation of symptoms and signs into mechanisms in neuropathic pain

  2003cited by this paper
• Diabetic neuropathy: a review emphasizing diagnostic methods.

  2003cited by this paper
• Neuropathic pain: clinical characteristics and diagnostic workup

  2002cited by this paper
• Pain elicited by blunt pressure: neurobiological basis and clinical relevance

  2002cited by this paper
• Neurogenic hyperalgesia versus painful hypoalgesia: two distinct mechanisms of neuropathic pain

  2002influential reference
• Quantitative assessment of neuropathic pain

  2001cited by this paper
• Sex differences in musculoskeletal pain.

  2001cited by this paper
• Neuronal plasticity: increasing the gain in pain.

  2000cited by this paper
• Wind-up of spinal cord neurones and pain sensation: much ado about something?

  2000cited by this paper
• Quantitative sensory testing: effect of site and skin temperature on thermal thresholds.

  2000cited by this paper
• Thermal and tactile perception thresholds in acute herpes zoster

  1999influential reference
• Pressure pain thresholds in different tissues in one body region. The influence of skin sensitivity in pressure algometry.

  1999cited by this paper
• Secondary hyperalgesia to punctate mechanical stimuli. Central sensitization to A-fibre nociceptor input.

  1999cited by this paper
• Secondary hyperalgesia and perceptual wind‐up following intradermal injection of capsaicin in humans

  1998cited by this paper
• Normative values of vibratory perception in 530 children, juveniles and adults aged 3-79 years.

  1998cited by this paper
• Postherpetic neuralgia: irritable nociceptors and deafferentation.

  1998cited by this paper
• Sex differences in the perception of noxious experimental stimuli: a meta‐analysis

  1998cited by this paper
• Spatial summation of heat pain: a reassessment

  1996influential reference
• Qualitatively altered nociception in chronic myofascial pain

  1996cited by this paper
• Paradoxical heat sensation in patients with multiple sclerosis. Evidence for a supraspinal integration of temperature sensation.

  1996cited by this paper
• Heat pain thresholds: normative data and repeatability

  1995cited by this paper
• Thresholds for the perception of pressure, sharpness, and mechanically evoked cutaneous pain: effects of laterality and repeated testing.

  1994cited by this paper
• Thermal testing: normative data and repeatability for various test algorithms.

  1994cited by this paper
• Hypotheses on the pathogenesis of herpes zoster—associated pain

  1994influential reference
• The effect of changes in temperature and humidity on the accuracy of von Frey hairs.

  1993cited by this paper
• Cool, warm, and heat‐pain detection thresholds

  1993cited by this paper
• Neuropathic pain and injured nerve: peripheral mechanisms.

  1991cited by this paper
• Differential effect of compression-ischaemia block on warm sensation and heat-induced pain.

  1991cited by this paper
• Thermal discrimination thresholds: a comparison of different methods

  1990cited by this paper
• Assessment of small and large fiber function in long‐term type 1 (insulin‐dependent) diabetic patients with and without painful neuropathy

  1988cited by this paper
• Methods of measurement of thermal thresholds

  1987cited by this paper
• Thermal sensibility changes during ischemie nerve block

  1984cited by this paper
• The behavioural management of anxiety, depression and pain: P.O. Davidson (Ed.), Brunne Mazel, New York, 1976, x + 197 pp.

  1979cited by this paper
• Pain terms: a list with definitions and notes on usage. Recommended by the IASP Subcommittee on Taxonomy.

  1979cited by this paper
• Painful peripheral states and sympathetic blocks.

  1978cited by this paper
• Mechanisms of first and second pain in the peripheral and central nervous systems.

  1977cited by this paper
• Intensive and extensive aspects of tactile sensitivity as a function of body part, sex, and laterality

  1968cited by this paper

• Differences in human assumed central sensitization between patients with radiating and non-radiating chronic low back pain: a cross-sectional observational study with special attention to sex.

  2026cites this paper
• Response to High‐Dose Topical Capsaicin in Neuropathic Pain: Absence of Deep Pain as a Predictor of Analgesic Effect

  2026cites this paper
• Pain modulation profiles in temporomandibular disorders with migraine and fibromyalgia

  2026cites this paper
• Applications of pelvic neurophysiology testing in clinical practice

  2026cites this paper
• Assessment of Sensitivity and Specificity of Common Sensory Tests in Diagnosing Digital Nerve Lacerations

  2026cites this paper
• Cytokines, Somatosensory Functioning, and Psychological Distress in Post-Breast Cancer Surgery Pain: A longitudinal study.

  2026cites this paper
• TrkA abundance is increased in cutaneous nerves in bortezomib-induced neuropathy.

  2026cites this paper
• Pressure pain sensitivity is more strongly associated with musculoskeletal pain among women and those with chronic diseases: results from a large population-based birth cohort study.

  2026cites this paper
• Double-blind randomized control trial investigating immediate changes in pain processing measures in response to dry needling to the lumbar multifidus in an asymptomatic population

  2026cites this paper
• The Impact of Familiarization on Pressure and Heat Pain Scores

  2026cites this paper
• The intrinsic reason why complementary tests (clinical neurophysiology, neuroimaging, skin biopsy) cannot establish the diagnosis of neuropathic pain

  2026cites this paper
• Reduced Descending Itch Inhibition in Peripheral Neuropathy Patients With Chronic Pruritus

  2026cites this paper
• A model-agnostic framework for dataset-specific selection of missing value imputation methods in pain-related numerical data

  2026cites this paper
• Brain Mechanisms of Pain Anticipation in Chronic Low Back Pain: Insights into Phenotypical Responses to Mind-Body Therapy.

  2026cites this paper
• Sex differences in pain-related biopsychosocial assessments in patients with axial spondyloarthritis

  2026cites this paper
• Coding of mechanical pain by myelinated and unmyelinated nociceptors in human hairy skin

  2026cites this paper
• Social skills moderate pain sensitivity during acute psychosocial stress: an experimental study using the Trier Social Stress Test.

  2026cites this paper
• Experimental Pain Research as an Effective Active Learning Method for Pain Education.

  2026cites this paper
• Quantitative Sensory Testing Following Orthopedic Trauma: A Longitudinal Multi-Site Feasibility Study.

  2026cites this paper
• Perceiving less or perceiving unreliably? Disentangling thermosensory sensitivity and precision in the contexts of ageing and neuropathy

  2026cites this paper
• Correlation of Mechanical Thresholds, Glasgow Composite Measure Pain Scale, and Sharp and Wheeler Grading Scale in Dogs with Acute Thoracolumbar Disc Extrusions

  2025cites this paper
• A Randomized Controlled Trial of Intraoperative Ketamine for Acute Postsurgical Pain after Breast Cancer Surgery: The Moderating Effect of Baseline Temporal Summation of Pain.

  2025cites this paper
• Endogenous pain modulation (EPM) changes after a course of exercise therapy in low back pain (LBP): A pilot feasibility study

  2025cites this paper
• Reduced functional resting-state connectivity in chronic pain patients with small fiber neuropathy.

  2025cites this paper
• Diagnostic accuracy of quantitative sensory testing for detecting small fiber impairment in polyneuropathy and diagnosing small fiber neuropathy.

  2025cites this paper
• What a Sham(e): Sham‐Controlled Conditioned Pain Modulation Effects on Pressure but Not Heat Pain Thresholds in Healthy Volunteers

  2025cites this paper
• Human Mutations in the TRPV1 Channel: Implications for Noxious Cold Sensation.

  2025cites this paper
• Quantitative sensory testing for detecting small fiber impairment-the same old story or finally evidence-based decision making?

  2025cites this paper
• Small Fiber Morphology and Function in Inclusion Body Myositis—A Multimodal Assessment Including Confocal Corneal Microscopy

  2025cites this paper
• Multimodal Management and Prognostic Factors in Post-Traumatic Trigeminal Neuropathic Pain Following Dental Procedures: A Retrospective Study

  2025cites this paper
• The diagnostic test performance of clinical point-of-care testing in relation to quantitative sensory testing for neurosensory injury among workers exposed to hand-arm vibration

  2025cites this paper
• Autonomic and sensory dysfunction in hypermobile Ehlers-Danlos syndrome: How do small fibers contribute?

  2025cites this paper
• Central and Peripheral Mechanisms of Neuropathic Pain.

  2025cites this paper
• Trans-scrotal Suspensory Ligament Release: A Novel Technique for Penile Length Augmentation.

  2025cites this paper
• Quantifying Pain: A Methodological Review of Pain Assessment in Exercise Science

  2025cites this paper
• Clinical characterization of neuropathic pain and small fiber impairment in neurofibromatosis

  2025cites this paper
• Comparison of nab-paclitaxel, paclitaxel, and oxaliplatin-induced peripheral neuro-pathy: a cross-sectional cohort study

  2025cites this paper
• Neuropathic pain in diabetic polyneuropathy: a 5-year prospective study.

  2025cites this paper
• Modifying quantitative sensory testing to investigate tactile sensory function and behavioral reactivity in children with intellectual and developmental disabilities: establishing feasibility and testing sex, autism, and self-injury effects

  2025cites this paper
• Serum neurofilament light chain and structural and Functional nerve fiber loss in painful and painless diabetic polyneuropathy.

  2025cites this paper
• Exploring the Spectrum of Temporal Summation and Conditioned Pain Modulation Responses in Pain‐Free Individuals Using a Tonic Heat Pain and Cold Pressor Test Paradigms

  2025influential citation
• Evaporative cooling for low-cost monitoring of flow of cerebrospinal fluid through shunts in patients with hydrocephalus.

  2025cites this paper
• Neuropathic Pain: A Comprehensive Bibliometric Analysis of Research Trends, Contributions, and Future Directions

  2025cites this paper
• The effect of mindfulness combined with exercise compared with a self-management guide on measures of nervous system sensitivity in individuals with chronic pain: a pilot randomised control trial

  2025cites this paper
• Quantitative Sensory Testing in Fibromyalgia Syndrome: A Scoping Review

  2025cites this paper
• Who is the patient with resistant myofascial temporomandibular disorders pain? A somatosensory, psychosocial, and genetic characterization

  2025cites this paper
• Microneurographic portrait of 19 patients with small fiber neuropathy-A pilot study.

  2025cites this paper
• Local cold injury affecting the hand and incident Raynaud’s phenomenon – a case report

  2025cites this paper
• Temporal Summation of Pain Varies Across Body Regions: A Cutaneous Laser Stimulation Study in Healthy Controls.

  2025cites this paper
• Small Fiber Neuropathy in Long COVID: A Cohort Study with Multimodal Assessment and Follow-Up

  2025cites this paper
• Effects of device color and sex on mice in von Frey Test.

  2025cites this paper
• Noziplastischer Schmerz (1): Konzept und Abgrenzung

  2025cites this paper
• The prevalence of neuropathic pain pathophysiology associated with ankle fracture: A study protocol

  2025cites this paper
• Validity and contributions to pain from the central aspects of pain questionnaire in rheumatoid arthritis

  2025cites this paper
• Small fibre neuropathy and sarcoidosis, target for diagnosis and treatment?

  2025cites this paper
• Diminished transient receptor vanilloid 1 on skin nerve fibers in painful bortezomib-induced peripheral neuropathy.

  2025cites this paper
• Bibliometric Analysis: Insights Into the Podiatric Medicine Landscape of Diabetic Sensory Peripheral Neuropathy and Genomics

  2025cites this paper
• Assessment of Mechanical Detection Thresholds in Healthy Participants and Patients With Neuropathy: A Comparison of OptiHair2 and Aesthesiometer II

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• Reply to Cohen et al.

  2025cites this paper
• Evaluating the association of transient receptor potential cation channel subfamily A member 1 gene polymorphisms with pain sensitivity: results from an adaptive recall by genotype study

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• Misdiagnosis in carpal tunnel syndrome: amyloidosis and other red flags. A narrative review

  2025cites this paper
• No evidence for a link between mental health symptoms and pain thresholds

  2025cites this paper
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  2025cites this paper
• Altered Sensory and Stress Responses in Atopic Dermatitis: Effects of Acute Stress on Lesional and Non‐Lesional Skin

  2025cites this paper
• Targeted Nipple Areola Complex Reinnervation in Gynecomastia Mastectomy: A Case Report

  2025influential citation
• Prevalence and Interplay of Hypervigilance and Kinesiophobia in TMD Patients: Implications in Clinical Outcomes

  2025cites this paper
• Subgrouping People With Acute Low Back Pain Based on Psychological, Sensory, and Motor Characteristics: A Cross‐Sectional Study

  2025influential citation
• Identification of small fiber neuropathy in neuronal intranuclear inclusion disease: A clinicopathological study

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• The presence and prognosis of nerve pathology following whiplash injury: a prospective cohort study

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• Touch inhibits cold: non-contact cooling suggests a thermotactile gating mechanism

  2025cites this paper
• Jaw muscle and joint psychophysics—relevance for clinical orofacial pain practice and research. A narrative review

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• Intra-Rater Reliability of Pressure Pain Threshold with Different Algometers in Healthy Participants

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