Placental Vasculature in Health and Disease

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Seminars in Thrombosis and Hemostasis

• Publication date

  2010-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1055/s-0030-1253453PMID 20490981
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Recombinant Vascular Endothelial Growth Factor 121 Infusion Lowers Blood Pressure and Improves Renal Function in Rats With Placental Ischemia-Induced Hypertension

  2010cited by this paper
• Reduction of circulating soluble Flt-1 alleviates preeclampsia-like symptoms in a mouse model

  2009cited by this paper
• Novel splice variants of sFlt1 are upregulated in preeclampsia.

  2009cited by this paper
• A prospective cohort study of the value of maternal plasma concentrations of angiogenic and anti-angiogenic factors in early pregnancy and midtrimester in the identification of patients destined to develop preeclampsia

  2009cited by this paper
• A Novel Human-Specific Soluble Vascular Endothelial Growth Factor Receptor 1: Cell Type-Specific Splicing and Implications to Vascular Endothelial Growth Factor Homeostasis and Preeclampsia

  2008cited by this paper
• Autoantibody From Women With Preeclampsia Induces Soluble Fms-Like Tyrosine Kinase-1 Production via Angiotensin Type 1 Receptor and Calcineurin/Nuclear Factor of Activated T-Cells Signaling

  2008cited by this paper
• Angiotensin receptor agonistic autoantibodies induce pre-eclampsia in pregnant mice

  2008cited by this paper
• VEGF inhibition and renal thrombotic microangiopathy.

  2008cited by this paper
• Putting pressure on pre-eclampsia

  2008cited by this paper
• A preeclampsia-like syndrome characterized by reversible hypertension and proteinuria induced by the multitargeted kinase inhibitors sunitinib and sorafenib.

  2008cited by this paper
• VEGF inhibition and renal thrombotic microangiopathy.

  2008cited by this paper
• A longitudinal study of angiogenic (placental growth factor) and anti-angiogenic (soluble endoglin and soluble vascular endothelial growth factor receptor-1) factors in normal pregnancy and patients destined to develop preeclampsia and deliver a small for gestational age neonate

  2008cited by this paper
• Dysregulation of the Circulating and Tissue-Based Renin–Angiotensin System in Preeclampsia

  2007cited by this paper
• Recombinant Vascular Endothelial Growth Factor 121 Attenuates Hypertension and Improves Kidney Damage in a Rat Model of Preeclampsia

  2007cited by this paper
• Intronic polyadenylation signal sequences and alternate splicing generate human soluble Fltl variants and regulate the abundance of soluble Flt1 in the placenta

  2007cited by this paper
• Uteroplacental ischemia results in proteinuric hypertension and elevated sFLT-1.

  2007cited by this paper
• Soluble endoglin and other circulating antiangiogenic factors in preeclampsia

  2007cited by this paper
• Decidual NK cells regulate key developmental processes at the human fetal-maternal interface

  2006cited by this paper
• Urinary Placental Growth Factor and Risk of Preeclampsia

  2006cited by this paper
• Soluble endoglin contributes to the pathogenesis of preeclampsia

  2006cited by this paper
• Soluble endoglin and other circulating antiangiogenic factors in preeclampsia.

  2006cited by this paper
• Evidence supporting that the excess of the sVEGFR-1 concentration in maternal plasma in preeclampsia has a uterine origin

  2005cited by this paper
• Angiotensin II type 1-receptor activating antibodies in renal-allograft rejection.

  2005cited by this paper
• Angiotensin II Type 1 Receptor Agonistic Antibodies Reflect Fundamental Alterations in the Uteroplacental Vasculature

  2005cited by this paper
• Maternal serum soluble fms-like tyrosine kinase 1 concentrations are not increased in early pregnancy and decrease more slowly postpartum in women who develop preeclampsia.

  2005cited by this paper
• Preeclampsia: a renal perspective.

  2005cited by this paper
• Circulating Angiogenic Factors and the Risk of Preeclampsia

  2005cited by this paper
• Soluble fms-like tyrosine kinase 1 is increased in preeclampsia but not in normotensive pregnancies with small-for-gestational-age neonates: relationship to circulating placental growth factor.

  2005cited by this paper
• The Role of the Anti-Angiogenic Factor Endostatin in Intrauterine Growth Restriction

  2005influential reference
• Angiotensin II type 1-receptor activating antibodies in renal-allograft rejection.

  2005cited by this paper
• AT1 receptor agonistic antibodies, hypertension, and preeclampsia.

  2004cited by this paper
• Association of extreme first-trimester free human chorionic gonadotropin-beta, pregnancy-associated plasma protein A, and nuchal translucency with intrauterine growth restriction and other adverse pregnancy outcomes.

  2004cited by this paper
• Developmental biology of the placenta and the origins of placental insufficiency.

  2004cited by this paper
• Insulin-like growth factor I is required for vessel remodeling in the adult brain.

  2004cited by this paper
• Morphometric evidence that villous development and fetoplacental angiogenesis are compromised by intrauterine growth restriction but not by pre-eclampsia.

  2004cited by this paper
• Angiogenic imbalance in the pathophysiology of preeclampsia: newer insights.

  2004influential reference
• Trophoblast differentiation during embryo implantation and formation of the maternal-fetal interface.

  2004cited by this paper
• Elevated Placental Soluble Vascular Endothelial Growth Factor Receptor-1 Inhibits Angiogenesis in Preeclampsia

  2004cited by this paper
• Insulin-like growth factor I plasmid therapy promotes in vivo angiogenesis.

  2004cited by this paper
• Fetal growth restriction due to placental disease.

  2004cited by this paper
• Circulating angiogenic factors and the risk of preeclampsia.

  2004cited by this paper
• Endothelial dysfunction and raised plasma concentrations of asymmetric dimethylarginine in pregnant women who subsequently develop pre-eclampsia.

  2003cited by this paper
• Localization of mRNA for vascular endothelial growth factor (VEGF), angiopoietins and their receptors during the peri-implantation period and early pregnancy in marmosets (Callithrix jacchus).

  2003cited by this paper
• The frequency and severity of placental findings in women with preeclampsia are gestational age dependent.

  2003cited by this paper
• Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) could contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia

  2003influential reference
• Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia.

  2003cited by this paper
• IGF-I receptor mutations resulting in intrauterine and postnatal growth retardation.

  2003cited by this paper
• Human cytotrophoblasts promote endothelial survival and vascular remodeling through secretion of Ang2, PlGF, and VEGF-C.

  2003cited by this paper
• A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer.

  2003cited by this paper
• Gestation stage-dependent intrauterine trophoblast cell invasion in the rat and mouse: novel endocrine phenotype and regulation.

  2003cited by this paper
• Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases.

  2003cited by this paper
• Possible angiogenic roles of insulin-like growth factor II and its receptors in uterine vascular adaptation to pregnancy.

  2003cited by this paper
• Second‐Trimester Maternal Serum Placental Growth Factor and Vascular Endothelial Growth Factor for Predicting Severe, Early‐Onset Preeclampsia

  2003cited by this paper
• Overexpression of the soluble vascular endothelial growth factor receptor in preeclamptic patients: pathophysiological consequences.

  2003cited by this paper
• Leptin: A Potential Marker of Placental Insufficiency

  2003cited by this paper
• Skin capillary density changes in normal pregnancy and pre-eclampsia

  2002cited by this paper
• Searching for preeclampsia genes: the current position.

  2002cited by this paper
• Vascular endothelial growth factor ligands and receptors that regulate human cytotrophoblast survival are dysregulated in severe preeclampsia and hemolysis, elevated liver enzymes, and low platelets syndrome.

  2002cited by this paper
• Altered placental development and intrauterine growth restriction in IGF binding protein-1 transgenic mice.

  2002cited by this paper
• Placental-fetal interrelationship in IUGR fetuses--a review.

  2002cited by this paper
• Hemochorial Placentation in the Primate: Expression of Vascular Endothelial Growth Factor, Angiopoietins, and Their Receptors Throughout Pregnancy1

  2002influential reference
• Human placental vascular development: vasculogenic and angiogenic (branching and nonbranching) transformation is regulated by vascular endothelial growth factor-A, angiopoietin-1, and angiopoietin-2.

  2002cited by this paper
• Early pregnancy levels of pregnancy-associated plasma protein a and the risk of intrauterine growth restriction, premature birth, preeclampsia, and stillbirth.

  2002cited by this paper
• Vascular growth factors and lymphangiogenesis.

  2002cited by this paper
• Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions

  2001cited by this paper
• Post-cyclosporine-mediated hypertension and nephropathy: amelioration by vascular endothelial growth factor.

  2001cited by this paper
• Structure and function of VEGF/VEGF-receptor system involved in angiogenesis.

  2001cited by this paper
• Vascular endothelial growth factor enhances glomerular capillary repair and accelerates resolution of experimentally induced glomerulonephritis.

  2001cited by this paper
• Differential inhibition of tumor angiogenesis by tie2 and vascular endothelial growth factor receptor‐2 dominant‐negative receptor mutants

  2001cited by this paper
• Developmental regulation of vascular endothelial growth/permeability factor messenger ribonucleic acid levels in and vascularization of the villous placenta during baboon pregnancy.

  2001cited by this paper
• The Regulation and Localization of Angiopoietin-1, -2, and Their Receptor Tie2 in Normal and Pathologic Human Placentae

  2001cited by this paper
• Preeclampsia: what we know and what we do not know.

  2000cited by this paper
• Angiopoietin-1 protects the adult vasculature against plasma leakage

  2000cited by this paper
• Tie-2 and angiopoietin-2 expression at the fetal-maternal interface: a receptor ligand model for vascular remodelling.

  2000cited by this paper
• AT(1) receptor agonistic antibodies from preeclamptic patients cause vascular cells to express tissue factor.

  2000cited by this paper
• Angiopoietin-1 and angiopoietin-2 activate trophoblast Tie-2 to promote growth and migration during placental development.

  2000cited by this paper
• Vascular endothelial growth factor accelerates renal recovery in experimental thrombotic microangiopathy.

  2000cited by this paper
• Mechanisms of angiogenesis and arteriogenesis

  2000cited by this paper
• Placental vascular morphogenesis.

  2000cited by this paper
• Pre-eclampsia

  2000cited by this paper
• Patients with preeclampsia develop agonistic autoantibodies against the angiotensin AT1 receptor.

  1999cited by this paper
• Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin-1.

  1999cited by this paper
• Prostacyclin and thromboxane changes predating clinical onset of preeclampsia: a multicenter prospective study.

  1999cited by this paper
• Current biology of VEGF-B and VEGF-C.

  1999cited by this paper
• Alternative splicing of vascular endothelial growth factor (VEGF)-R1 (FLT-1) pre-mRNA is important for the regulation of VEGF activity.

  1999cited by this paper
• Structure, expression and receptor-binding properties of placenta growth factor (PlGF).

  1999cited by this paper
• Biologic significance of angiopoietin-2 expression in human hepatocellular carcinoma.

  1999cited by this paper
• IL-10 is an autocrine inhibitor of human placental cytotrophoblast MMP-9 production and invasion.

  1999cited by this paper
• Direct actions of angiopoietin-1 on human endothelium: evidence for network stabilization, cell survival, and interaction with other angiogenic growth factors.

  1999cited by this paper
• Preeclampsia: an excessive maternal inflammatory response to pregnancy.

  1999cited by this paper
• Vascular Endothelial Growth Factor Signals Endothelial Cell Production of Nitric Oxide and Prostacyclin through Flk-1/KDR Activation of c-Src*

  1999cited by this paper
• Angiopoietin-1 induces sprouting angiogenesis in vitro.

  1998cited by this paper
• Endothelial Dysfunction in Preeclampsia

  1998cited by this paper
• Predictive Value of Plasma Thrombomodulin in Preeclampsia and Gestational Hypertension

  1998cited by this paper
• A vascular endothelial growth factor antagonist is produced by the human placenta and released into the maternal circulation.

  1998cited by this paper
• First trimester utero-placental circulation: maternal-fetal interaction.

  1998cited by this paper
• Vascular Endothelial Growth Factor Induces Endothelial Fenestrations In Vitro

  1998cited by this paper
• The biology of vascular endothelial growth factor.

  1997cited by this paper
• Regulation of human placental development by oxygen tension.

  1997cited by this paper
• Mechanisms of angiogenesis

  1997cited by this paper

• An Endogenous Aryl Hydrocarbon Receptor Ligand Dysregulates Endothelial Functions, Transcriptome, and Phosphoproteome.

  2025cites this paper
• Convergent evolution of complex adaptive traits modulates angiogenesis in high-altitude Andean and Himalayan human populations

  2025cites this paper
• An endogenous aryl hydrocarbon receptor ligand induces preeclampsia‐like phenotypes in rats

  2024cites this paper
• Proangiogenic Macrophage Development in Human Prenatal Stage: A Key Element in Maternal-Fetal Medicine Puzzle

  2024cites this paper
• Impact of ectopic calcification on vascular oxygenation in placental dysfunction models: Simultaneous in vivo assessment with multi-parametric ultrasound and photoacoustic imaging

  2023cites this paper
• Convergent evolution of complex adaptive traits enabled human life at high altitudes

  2023cites this paper
• Genetic Polymorphisms of Vascular Endothelial Growth Factor in Neonatal Pathologies: A Systematic Search and Narrative Synthesis of the Literature

  2023cites this paper
• Blood Plasma Calorimetric Profiles of Women with Preeclampsia: Effect of Oxidative Stress

  2023cites this paper
• Trans-differentiation of trophoblast stem cells: implications in placental biology

  2022cites this paper
• Placental DNA methylation in pregnancies complicated by maternal diabetes and/or obesity: State of the art and research gaps

  2022cites this paper
• Clinical correlation between volume of placental lakes and non-reassuring fetal status: a retrospective cohort study.

  2022cites this paper
• Implications of VEGF gene sequence variations and its expression in recurrent pregnancy loss.

  2021cites this paper
• Untersuchung des Einflusses von Vitamin D3 auf die plazentare Angiogenese in vitro

  2021cites this paper
• Comparison of prenatal functional markers of retardation of fetal growth and delayed fetal development with expression of vascular growth factors in the placenta

  2021cites this paper
• Maternal tetrahydrofolate reductase gene mutation in patients with missed abortion

  2019cites this paper
• Damaging Variants in Proangiogenic Genes Impair Growth in Fetuses with Cardiac Defects.

  2019influential citation
• Placenta‐conditioned extracellular matrix (ECM) activates breast cancer cell survival mechanisms: A key for future distant metastases

  2019cites this paper
• The impact of the maternal–foetal environment on outcomes of surgery for congenital heart disease in neonates†

  2018cites this paper
• The effects of flavonoids in reducing trophoblast oxidative stress and apoptosis

  2018cites this paper
• Inhibition of 11&bgr;‐hydroxysteroid dehydrogenase 2 by the fungicides itraconazole and posaconazole

  2017cites this paper
• Maternal methyltetrahydrofolate reductase gene mutation in patients with missed abortions

  2017cites this paper
• Expression of factors involved in the regulation of angiogenesis in the full-term human placenta: Effects of in vitro fertilization.

  2016cites this paper
• KDR gene polymorphisms and idiopathic recurrent spontaneous abortion

  2016cites this paper
• The Presence of Vascular Mimicry Predicts High Risk of Clear Cell Renal Cell Carcinoma after Radical Nephrectomy.

  2016cites this paper
• Comparison of the thrombophilic gene polymorphisms and recurrent pregnancy loss: Results on combined gene effect of FVLeiden, FVR2, FXIII, MTHFR(A1298C and C677T), PAI-1 4G/5G and ACE I/D genes in RPL Women from Misk/Belarus and Canakkale - Sivas/Turkey

  2016cites this paper
• Acute kidney injury in pregnancy

  2016cites this paper
• The role of endometrial blood vessels in the formation of the trophoblast and placenta

  2016cites this paper
• Pregnancy Associated Kidney Diseases

  2015cites this paper
• Multiple Inherited Thrombophilic Gene Polymorphisms in Spontaneous Abortions in Turkish Population

  2015cites this paper
• Blocking Endogenous Leukemia Inhibitory Factor During Placental Development in Mice Leads to Abnormal Placentation and Pregnancy Loss

  2015cites this paper
• 2,3,7,8-Tetrachlorodibenzo-p-dioxin differentially suppresses angiogenic responses in human placental vein and artery endothelial cells.

  2015cites this paper
• The Effects of Heme Oxygenase By-Products on the Proliferation and Invasion of HUVECs, HTR-8/SVneo Cells, 3A(tPA 30-1) Cells, and HESCs Under Varying Oxygen Concentrations

  2015influential citation
• Gene-gene interactions and gene polymorphisms of VEGFA and EG-VEGF gene systems in recurrent pregnancy loss

  2014cites this paper
• FSH Receptor (FSHR) Expression in Human Extragonadal Reproductive Tissues and the Developing Placenta, and the Impact of Its Deletion on Pregnancy in Mice1

  2014cites this paper
• The effect of heat shock protein 27 on extravillous trophoblast differentiation and on eukaryotic translation initiation factor 4E expression.

  2014cites this paper
• Signaling through FSH receptors on human umbilical vein endothelial cells promotes angiogenesis.

  2014cites this paper
• Development of the hemochorial maternal vascular spaces in the placenta through endothelial and vasculogenic mimicry.

  2014cites this paper
• Welcome to Seminars in Thrombosis & Hemostasis 2014

  2014cites this paper
• Factores vasculares implicados en la preeclampsia

  2013cites this paper
• MicroRNAs in Human Placental Development and Pregnancy Complications

  2013cites this paper
• Identification of soluble CD146 as a regulator of trophoblast migration: potential role in placental vascular development

  2013cites this paper
• Placental trophoblast cell differentiation: physiological regulation and pathological relevance to preeclampsia.

  2013cites this paper
• Anti-Angiogenic Effects of Diltiazem , Imatinib , and Bevacizumab in the CAM Assay

  2013cites this paper
• Vascular endothelial growth factors and their receptors and regulators in gestational trophoblastic diseases and normal placenta.

  2012cites this paper
• Maternal and neonatal separation and mortality associated with concurrent admissions to intensive care units

  2012cites this paper
• Regulation of Placental Autophagy by the Bcl-2 Family Proteins Myeloid Cell Leukemia Factor 1 (Mcl-1) and Matador/Bcl-2 Related Ovarian Killer (Mtd/Bok)

  2012cites this paper
• Gestational Hypertension, Preeclampsia, and Eclampsia

  2012cites this paper
• The involvement of eukaryotic translation initiation factor 4E in extravillous trophoblast cell function.

  2012cites this paper
• Acute kidney injury in pregnancy: a clinical challenge.

  2012cites this paper
• Adverse Fetal and Neonatal Outcomes Associated with a Life-Long High Fat Diet: Role of Altered Development of the Placental Vasculature

  2012cites this paper
• The Hemodynamic Basis for Positional- and Inter-Fetal Dependent Effects in Dual Arterial Supply of Mouse Pregnancies

  2012cites this paper
• Single-nucleotide polymorphisms in genes involved in placental function and unexplained stillbirth.

  2012cites this paper
• Nitric oxide generation affects pro- and anti-angiogenic growth factor expression in primary human trophoblast.

  2011cites this paper
• Preeclampsia, a Disease of the Maternal Endothelium: The Role of Antiangiogenic Factors and Implications for Later Cardiovascular Disease

  2011cites this paper
• Genetic association studies of angiogenesis- and vasoconstriction-related genes in women with recurrent pregnancy loss: a systematic review and meta-analysis.

  2011cites this paper
• Cancer in Pregnancy and Lactation: The Motherisk Guide

  2011cites this paper
• Investigating the psychobiological stress response and the conversion of cortisol to cortisone in human pregnancy

  2011cites this paper