Caco-2 cells can be used to assess human iron bioavailability from a semipurified meal.

No abstract is available for this paper.

• Publication year

  2000

• Venue

  Journal of NutriLife

• Publication date

  2000-05-01

• Fields of study

  Agricultural and Food Sciences, Medicine, Chemistry

• Identifiers
  DOI 10.1093/JN/130.5.1329PMID 10801938
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Transferrin stimulates iron absorption, exocytosis, and secretion in cultured intestinal cells.

  1999cited by this paper
• Caco-2 cell ferritin formation predicts nonradiolabeled food iron availability in an in vitro digestion/Caco-2 cell culture model.

  1998cited by this paper
• Decreased citrate improves iron availability from infant formula: application of an in vitro digestion/Caco-2 cell culture model.

  1998cited by this paper
• Iron uptake is enhanced in Caco-2 cell monolayers by cysteine and reduced cysteinyl glycine.

  1997cited by this paper
• Ferrous iron uptake but not transfer is down-regulated in Caco-2 cells grown in high iron serum-free medium.

  1996cited by this paper
• The Caco-2 cell culture system can be used as a model to study food iron availability.

  1996cited by this paper
• Caco-2 cell iron uptake from meat and casein digests parallels in vivo studies: use of a novel in vitro method for rapid estimation of iron bioavailability.

  1996cited by this paper
• The influence of different protein sources on phytate inhibition of nonheme-iron absorption in humans.

  1996influential reference
• Reduction of Fe(III) is required for uptake of nonheme iron by Caco-2 cells.

  1995cited by this paper
• Regulation of iron uptake and transport by transferrin in Caco-2 cells, an intestinal cell line.

  1994cited by this paper
• Role of redox systems on Fe3+ uptake by transformed human intestinal epithelial (Caco-2) cells.

  1994cited by this paper
• Soy protein, phytate, and iron absorption in humans.

  1992cited by this paper
• Contributions of heme and nonheme iron to human nutrition.

  1992cited by this paper
• Calcium supplementation: effect on iron absorption.

  1991cited by this paper
• Dose-dependent inhibitory effect of phenolic compounds in foods on nonheme-iron absorption in men.

  1991cited by this paper
• Assessment of dietary determinants of nonheme-iron absorption in humans and rats.

  1991influential reference
• Calcium: effect of different amounts on nonheme- and heme-iron absorption in humans.

  1991cited by this paper
• Assessment of the role of nonheme-iron availability in iron balance.

  1991cited by this paper
• Iron absorption in humans as influenced by bovine milk proteins.

  1989influential reference
• In vitro studies of iron bioavailability. Probing the concentration and oxidation-reduction of pinto bean iron with ferrous chromogens.

  1989cited by this paper
• Food iron absorption.

  1989cited by this paper
• The role of vitamin C in iron absorption.

  1989cited by this paper
• Iron absorption in humans: bovine serum albumin compared with beef muscle and egg white.

  1988influential reference
• Phytates and the inhibitory effect of bran on iron absorption in man.

  1987cited by this paper
• Enterocyte-like differentiation and polarization of the human colon carcinoma cell line Caco-2 in culture

  1983cited by this paper
• The effects of organic acids, phytates and polyphenols on the absorption of iron from vegetables

  1983cited by this paper
• Dietary Fiber—Iron Interactions

  1982cited by this paper
• The inhibitory effect of soy products on nonheme iron absorption in man.

  1981influential reference
• Phytic acid interactions in food systems.

  1980influential reference
• INTERACTION OF VITAMIN C AND IRON *

  1980cited by this paper
• Food iron absorption in human subjects. V. Effects of the major dietary constituents of semisynthetic meal.

  1979cited by this paper
• Biological availability to the rat of intrinsic and extrinsic iron with soybean protein isolates.

  1978cited by this paper
• Vitamin C, the common cold, and iron absorption.

  1977cited by this paper
• Food iron absorption in human subjects. III. Comparison of the effect of animal proteins on nonheme iron absorption.

  1976cited by this paper
• Food iron absorption. I. Use of semisynthetic diet to study absorption of nonheme iron.

  1975cited by this paper
• The effect of tea on iron absorption.

  1975cited by this paper
• A simple technique for measuring storage iron concentrations in formalinised liver samples.

  1968cited by this paper
• A simple technique for measuring storage iron concentrations in formalinised liver samples.

  1968cited by this paper
• [IRON METABOLISM].

  1964influential reference
• Modified reagents for determination of urea and ammonia.

  1962cited by this paper
• Protein measurement with the Folin phenol reagent.

  1951influential reference

• Assessing Iron Intake During the Complementary Feeding Period (6 Months to 2 Years) in Bangladesh

  2025cites this paper
• Mathematical modeling reveals ferritin as the strongest cellular driver of dietary iron transfer block in enterocytes

  2025cites this paper
• Stable Natural Iron Complex Micronutrient Powder for Enhanced Cellular Uptake

  2025cites this paper
• Ferrous nutritional metal-organic framework as food fortificant

  2025cites this paper
• Effects of soy protein on alleviating iron deficiency anemia in suckling rats with different iron supplements

  2024cites this paper
• Bioaccessibility and Caco-2 Cell Uptake of Iron Chlorophyllin Using A Biologically Relevant Digestion Model.

  2024cites this paper
• Iron deficiency anemia: a critical review on iron absorption, supplementation and its influence on gut microbiota.

  2024cites this paper
• The Beneficial Impact of Iron-Fortified Complementary Feeding in the Burden of Iron Deficiency Anaemia (IDA) in Children of Bangladesh

  2024cites this paper
• Efficiency of Coriandrum sativum (Linn.) and Petroselinum crispum (Mill.) in Enhancing Iron Absorption: An In Silico and In Vitro Approach

  2022cites this paper
• Absorption of iron from Tegillarca granosa using an in vitro simulated digestion and Caco-2/HepG2 co-culture system.

  2022cites this paper
• Sneak-peek into iron deficiency anemia in India: The need for food-based interventions and enhancing iron bioavailability.

  2022cites this paper
• Fortification of foods with nano-iron: its uptake and potential toxicity: current evidence, controversies, and research gaps.

  2022cites this paper
• Bioavailability of iron from novel hydrogen reduced iron powders: Studies in Caco-2 cells and rat model.

  2021cites this paper
• Retention, stability, iron bioavailability and sensory evaluation of extruded rice fortified with iron, folic acid and vitamin B12

  2020cites this paper
• Chondroitin sulfate and its nanocomposites with protamine or chitosan stabilize and deliver available nanosized iron.

  2020cites this paper
• Advances in Nanoliposomes Production for Ferrous Sulfate Delivery

  2020cites this paper
• Iron deficiency anemia: A comprehensive review on iron absorption, bioavailability and emerging food fortification approaches

  2020cites this paper
• Mass spectrometry-based analytical developments to link iron speciation to iron bioavailability in maize.

  2019cites this paper
• Advantages and limitations of in vitro and in vivo methods of iron and zinc bioavailability evaluation in the assessment of biofortification program effectiveness

  2018cites this paper
• Challenges in Optimal Utilization of Bioactive Molecules Clinically

  2018cites this paper
• Glutathione and the cytosolic heme pool

  2018cites this paper
• In vitro Approaches for Investigating the Bioaccessibility and Bioavailability of Dietary Nutrients and Bioactive Metabolites

  2018cites this paper
• Evaluation of exposure to fluoride in child population of North Argentina

  2017cites this paper
• Natural Fe isotope fractionation in an intestinal Caco-2 cell line model

  2017cites this paper
• Mechanisms of Iron Uptake from Ferric Phosphate Nanoparticles in Human Intestinal Caco-2 Cells

  2017cites this paper
• IRON ABSORPTION IMPROVEMENT : AN ADDITIONAL HEALTH BENEFIT FOR CERTAIN PROBIOTICS , IN VITRO AND IN VIVO STUDY

  2017cites this paper
• Evaluation of Iron Bioavailability in Caco-2 cell Culture Model: Modification of the Original Method

  2016cites this paper
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  2016cites this paper
• The effects of hydrothermal processing and germination on Fe speciation and Fe bioaccessibility to human intestinal Caco-2 cells in Tartary buckwheat.

  2016cites this paper
• Protein iron and zinc content and bioaccessibility of a ready-to-eat sorghum and cowpea meal developed for 2-to 5-year old African children

  2016cites this paper
• Soybean extracts increase cell surface ZIP4 abundance and cellular zinc levels: a potential novel strategy to enhance zinc absorption by ZIP4 targeting.

  2015cites this paper
• Sucrosomial Iron®: A New Highly Bioavaible Oral Iron Supplement

  2015cites this paper
• Calcium as a nutrient involved in the synthesis and localization of proteins that facilitate iron uptake and efflux in enterocytes

  2015cites this paper
• Mineral nutrient content and iron bioavailability in common and Hawaiian seaweeds assessed by an in vitro digestion/Caco-2 cell model

  2015cites this paper
• The gastrointestinal uptake of titanium dioxide nanoparticles : studies on Caco-2 cells, perfused intestine and in vivo dietary intake in the rat (Rattus norvegicus)

  2015cites this paper
• In vitro iron absorption of α-lactalbumin hydrolysate-iron and β-lactoglobulin hydrolysate-iron complexes.

  2014cites this paper
• Pharmacokinetic Compatibility of Ginsenosides and Schisandra Lignans in Shengmai-san: From the Perspective of P-Glycoprotein

  2014cites this paper
• ptake of different crystal structures of TiO 2 nanoparticles by Caco-2 ntestinal cells

  2014cites this paper
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  2014cites this paper
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  2014cites this paper
• Uptake of different crystal structures of TiO₂ nanoparticles by Caco-2 intestinal cells.

  2014cites this paper
• Glutathione‐enriched baker's yeast: production, bioaccessibility and intestinal transport assays

  2014cites this paper
• Microfluidic chip for monitoring Ca2+ transport through a confluent layer of intestinal cells

  2014cites this paper
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  2014cites this paper
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  2013cites this paper
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  2013cites this paper
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  2013cites this paper
• Arsenic speciation in Chinese Herbal Medicines and human health implication for inorganic arsenic.

  2013cites this paper
• Kiwifruit and mineral nutrition.

  2013cites this paper
• Tea and Iron Metabolism

  2013cites this paper
• Application of in vitro bioaccessibility and bioavailability methods for calcium, carotenoids, folate, iron, magnesium, polyphenols, zinc, and vitamins B6, B12, D, and E

  2012influential citation
• Nutritionally Enhanced Staple Food Crops

  2012cites this paper
• Evidence for an enhancing effect of alginate on iron availability in Caco-2 cells.

  2012cites this paper
• Dephytinisation of Sangak and Barbari bread made from different extraction rate flours increases iron and zinc bioaccessibility in Caco‐2 cells

  2012cites this paper
• Comparison between in vitro and in vivo methods to screen iron bioavailability

  2012cites this paper
• Effect of dietary protein on heme iron uptake by Caco-2 cells

  2011cites this paper
• Organic acid bioavailability from banana and sweet potato using an in vitro digestion and Caco-2 cell model

  2011cites this paper
• Cholesterol Ester and Free Fatty Acids Are Modulated by Policosanol in CaCo-2 Intestinal Cells

  2011cites this paper
• Preparation and characterization of iron-containing liposomes: their effect on soluble iron uptake by Caco-2 cells

  2011influential citation
• The Effect of Cooking on Formation of Bioavailable Species of Iron from Chicken Breast Muscle

  2011cites this paper
• Seaweed Digestibility and Methods used for Digestibility Determination

  2011cites this paper
• Caco-2 cell uptake of Ca, Mg and Fe from biscuits as affected by enrichment with pseudocereal/inulin mixtures

  2011cites this paper
• Phytic acid content and "in vitro" iron, calcium and zinc bioavailability in bakery products: The effect of processing

  2011cites this paper
• The use of caco-2 cells to estimate fe absorption in humans--a critical appraisal.

  2010cites this paper
• In vitro approach (solubility and Caco-2 uptake) to compare Cu availability from model cookies

  2010cites this paper
• Does the pelleting process affect the nutritive value of a pre-starter diet for suckling piglets? Ex vivo studies on mineral absorption.

  2010cites this paper
• Iron uptake by Caco-2 cells following in vitro digestion: effects of heat treatments of pork meat and pH of the digests.

  2010cites this paper
• Intake of Maillard reaction products reduces iron bioavailability in male adolescents.

  2009cites this paper
• Nutriomic analysis of fresh and processed fruit products. 2. During in vitro simultaneous molecular passages using Caco-2 cell monolayers.

  2009cites this paper
• In Vitro Estimates of Iron Bioavailability in Some Kenyan Complementary Foods

  2009cites this paper
• Receptor-mediated uptake of ferritin-bound iron by human intestinal Caco-2 cells.

  2009cites this paper
• Challenges and advances in nanoparticle-based oral insulin delivery

  2009cites this paper
• Characterization of Caco-2 and HT29-MTX cocultures in an in vitro digestion/cell culture model used to predict iron bioavailability.

  2009cites this paper
• Effect of dietary ligands and food matrices on zinc uptake in Caco-2 cells: implications in assessing zinc bioavailability.

  2008cites this paper
• Effects of dietary factors on iron uptake from ferritin by Caco-2 cells.

  2008cites this paper
• Caseinophosphopeptide-Bound Iron: Protective Effect against Gut Peroxidation

  2008cites this paper
• Comparison of iron uptake from reduced iron powder and FeSO4 using the Caco-2 cell model: effects of ascorbic acid, phytic acid, and pH.

  2008cites this paper
• Interactions between ethylenediaminetetraacetic acid (EDTA) and iron absorption pathways, in the Caco-2 model.

  2008cites this paper
• An overview of methods for assessment of iron bioavailability from foods nutritionally enhanced through biotechnology.

  2007cites this paper
• Nonheme iron absorption in young women is not influenced by purified sulfated and unsulfated glycosaminoglycans.

  2007cites this paper
• Impact of modifying tea–biscuit composition on phytate levels and iron content and availability

  2007cites this paper
• Dietary factors influencing non-heme iron absorption

  2007cites this paper
• Diversified strategies for improving iron bioavailability of maize

  2007cites this paper
• Gastric digestion of pea ferritin and modulation of its iron bioavailability by ascorbic and phytic acids in caco-2 cells.

  2007cites this paper
• Smaller iron particle size improves bioavailability of hydrogen-reduced iron–fortified bread

  2006cites this paper
• Transport of calcium across caco-2 cells in the presence of inositol hexakisphosphate

  2006cites this paper
• Calcium, iron and zinc uptakes by Caco-2 cells from white beans and effect of cooking

  2006cites this paper
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  2006cites this paper
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  2006cites this paper
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  2006cites this paper
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  2006cites this paper
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  2006cites this paper
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  2006cites this paper
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  2006cites this paper
• Algorithms to assess non-heme iron bioavailability.

  2005cites this paper
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  2005cites this paper
• The precision of in vitro methods and algorithms for predicting the bioavailability of dietary iron.

  2005cites this paper
• Milk Proteins and Iron Absorption: Contrasting Effects of Different Caseinophosphopeptides

  2005cites this paper
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  2005influential citation
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