Activation of cAMP-response-element-binding protein (CREB) after focal cerebral ischemia stimulates neurogenesis in the adult dentate gyrus.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Proceedings of the National Academy of Sciences of the United States of America

• Publication date

  2004-06-22

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1073/PNAS.0401063101PMID 15197280PMCID PMC438997
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Targeting the CREB pathway for memory enhancers

  2003cited by this paper
• Expression of Inducible Nitric Oxide Synthase after Focal Cerebral Ischemia Stimulates Neurogenesis in the Adult Rodent Dentate Gyrus

  2003cited by this paper
• Generation of Functional Inhibitory Neurons in the Adult Rat Hippocampus

  2003cited by this paper
• Cdk5 activation induces hippocampal CA1 cell death by directly phosphorylating NMDA receptors

  2003cited by this paper
• Endogenously Produced Neurotrophins Regulate Survival and Differentiation of Cortical Progenitors via Distinct Signaling Pathways

  2003cited by this paper
• Regeneration of hippocampal pyramidal neurons after ischemic brain injury by recruitment of endogenous neural progenitors.

  2002cited by this paper
• Reversible inhibition of CREB/ATF transcription factors in region CA1 of the dorsal hippocampus disrupts hippocampus-dependent spatial memory.

  2002cited by this paper
• Localization of Phosphorylated cAMP Response Element-Binding Protein in Immature Neurons of Adult Hippocampus

  2002cited by this paper
• An essential role for a MEK-C/EBP pathway during growth factor-regulated cortical neurogenesis.

  2002cited by this paper
• Dietary restriction enhances neurotrophin expression and neurogenesis in the hippocampus of adult mice

  2002cited by this paper
• Expression of constitutively active CREB protein facilitates the late phase of long-term potentiation by enhancing synaptic capture.

  2002cited by this paper
• Neurogenesis in the adult is involved in the formation of trace memories

  2001cited by this paper
• Neurogenesis in dentate subgranular zone and rostral subventricular zone after focal cerebral ischemia in the rat

  2001cited by this paper
• Chronic Antidepressant Treatment Increases Neurogenesis in Adult Rat Hippocampus

  2000cited by this paper
• Induction of neurogenesis in the neocortex of adult mice

  2000cited by this paper
• BDNF upregulation during declarative memory formation in monkey inferior temporal cortex

  2000cited by this paper
• Dietary restriction increases the number of newly generated neural cells, and induces BDNF expression, in the dentate gyrus of rats

  2000cited by this paper
• CREB Activation Induces Adipogenesis in 3T3-L1 Cells

  2000cited by this paper
• Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus

  1999cited by this paper
• Learning enhances adult neurogenesis in the hippocampal formation

  1999cited by this paper
• Mediation by a CREB family transcription factor of NGF-dependent survival of sympathetic neurons.

  1999cited by this paper
• Proliferation of granule cell precursors in the dentate gyrus of adult monkeys is diminished by stress.

  1998cited by this paper
• Increased Neurogenesis in the Dentate Gyrus After Transient Global Ischemia in Gerbils

  1998cited by this paper
• Multipotent neural precursors can differentiate toward replacement of neurons undergoing targeted apoptotic degeneration in adult mouse neocortex.

  1997cited by this paper
• More hippocampal neurons in adult mice living in an enriched environment

  1997cited by this paper
• Differentiation of adult hippocampus-derived progenitors into olfactory neurons in vivo

  1996cited by this paper
• Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation

  1996cited by this paper
• Differentiation of newly born neurons and glia in the dentate gyrus of the adult rat.

  1993cited by this paper
• Regulation of gene expression in hippocampal neurons by distinct calcium signaling pathways.

  1993cited by this paper
• Direct evidence for loss and replacement of projection neurons in adult canary brain

  1993cited by this paper
• Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system.

  1992cited by this paper
• Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133.

  1989cited by this paper
• The new stereological tools: Disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis

  1988cited by this paper

• Aerobic exercise training improves learning and memory performance in hypoxic-exposed rats by activating the hippocampal PKA–CREB–BDNF signaling pathway

  2025cites this paper
• Exploring the memory: existing activity-dependent tools to tag and manipulate engram cells

  2024cites this paper
• Enhanced fear memory after social defeat in mice is dependent on interleukin-1 receptor signaling in glutamatergic neurons

  2024cites this paper
• Decreased Astrocytic CCL5 by MiR-324-5p Ameliorates Ischemic Stroke Injury via CCR5/ERK/CREB Pathway

  2024cites this paper
• The Role of Hyperbaric Oxygen Therapy in Neuroregeneration and Neuroprotection: A Review

  2024cites this paper
• Digestive and Absorptive Properties of the Antarctic Krill Tripeptide Phe-Pro-Phe (FPF) and Its Auxiliary Memory-Enhancing Effect.

  2024cites this paper
• Mechanism of S100A9-mediated astrocyte activation via TLR4/NF-κB in Parkinson's disease.

  2024cites this paper
• Early-life bisphenol A exposure causes detrimental age-related changes in anxiety, depression, learning, and memory in juvenile and adult male rats: Involvement of NMDAR/PSD-95-PTEN/AKT signaling pathway.

  2024cites this paper
• nNOS and Neurological, Neuropsychiatric Disorders: A 20-Year Story

  2023cites this paper
• Crosstalk between Adult Hippocampal Neurogenesis and Its Role in Alzheimer's Disease.

  2023cites this paper
• CREB: A multifaceted transcriptional regulator of neural and immune function in CNS tumors.

  2023cites this paper
• Role of NAD+ and FAD in Ischemic Stroke Pathophysiology: An Epigenetic Nexus and Expanding Therapeutic Repertoire

  2022cites this paper
• Histamine H3R antagonist counteracts the impaired hippocampal neurogenesis in Lipopolysaccharide-induced neuroinflammation.

  2022cites this paper
• Late Permian High-Ti and Low-Ti Basalts in the Songpan–Ganzi Terrane: Continental Breakup of the Western Margin of the South China Block

  2022cites this paper
• Dl-3-n-butylphthalide inhibits neuroinflammation by stimulating foxp3 and Ki-67 in an ischemic stroke model

  2021cites this paper
• Thioperamide Alleviates Lipopolysaccharide-Induced Neuroinflammation and Promotes Neurogenesis by Histamine Dependent Activation of H2R/PKA/CREB Pathway

  2021cites this paper
• Agonistic analog of growth hormone–releasing hormone promotes neurofunctional recovery and neural regeneration in ischemic stroke

  2021cites this paper
• The Effect of Monosodium Glutamate on Neuronal Signaling Molecules in the Hippocampus and the Neuroprotective Effects of Omega-3 Fatty Acids.

  2021cites this paper
• Insulin-Like Growth Factor 2 (IGF-2) Regulates Neuronal Density and IGF-2 Distribution Following Hippocampal Intracerebral Hemorrhage.

  2020cites this paper
• Impact of a Histone Deacetylase Inhibitor—Trichostatin A on Neurogenesis after Hypoxia-Ischemia in Immature Rats

  2020cites this paper
• Treadmill exercise ameliorates memory impairment through ERK-Akt-CREB-BDNF signaling pathway in cerebral ischemia gerbils

  2020cites this paper
• Histamine H3 Receptor Antagonist Enhances Neurogenesis and Improves Chronic Cerebral Hypoperfusion-Induced Cognitive Impairments

  2020cites this paper
• Antineuroinflammatory effects of dl-3-n-butylphthalide conferred by stimulation of Foxp3 and Ki-67 in an ischemic stroke model CURRENT STATUS: UNDER REVIEW

  2020cites this paper
• Antineuroinflammatory effects of dl-3-n-butylphthalide conferred by stimulation of Foxp3 and Ki-67 in an ischemic stroke model CURRENT STATUS: POSTED

  2020cites this paper
• Developmental exposure to diesel exhaust upregulates transcription factor expression, decreases hippocampal neurogenesis, and alters cortical lamina organization: relevance to neurodevelopmental disorders

  2020cites this paper
• Neuroprotective effects of Camellia nitidissima Chi leaf extract in hydrogen peroxide‐treated human neuroblastoma cells and its molecule mechanisms

  2020cites this paper
• Naoluo Xintong capsule ameliorates apoptosis induced by endoplasmic reticulum stress in rats with cerebral ischemia/ reperfusion injury.

  2020cites this paper
• Long-term Surgical and Chemical Castration Deteriorates Memory Function Through Downregulation of PKA/CREB/BDNF and c-Raf/MEK/ERK Pathways in Hippocampus

  2019cites this paper
• Pseudoginsenoside-F11 improves long-term neurological function and promotes neurogenesis after transient cerebral ischemia in mice.

  2019cites this paper
• Innate Immune Signaling and Its Role in Metabolic and Cardiovascular Diseases.

  2019cites this paper
• Silencing MicroRNA-134 Alleviates Hippocampal Damage and Occurrence of Spontaneous Seizures After Intraventricular Kainic Acid-Induced Status Epilepticus in Rats

  2019cites this paper
• Activation of CREB-binding protein ameliorates spinal cord injury in tabersonine treatment by suppressing NLRP3/Notch signaling

  2019cites this paper
• The therapeutic effect of quetiapine on cognitive impairment associated with 5-HT1A presynaptic receptor involved schizophrenia.

  2019cites this paper
• Mechanisms of neural differentiation and integration.

  2019cites this paper
• Recent advances in the neurobiology and neuropharmacology of Alzheimer's disease.

  2018cites this paper
• Clonidine preconditioning improved cerebral ischemia‐induced learning and memory deficits in rats via ERK1/2‐CREB/ NF‐&kgr;B‐NR2B pathway

  2018cites this paper
• Influence of isoflurane exposure in pregnant rats on the learning and memory of offsprings

  2018cites this paper
• Endogenous activity regulates the early development of adult-born neurons in the mouse olfactory bulb

  2018cites this paper
• Genetic Pathways of Neuroregeneration in a Novel Mild Traumatic Brain Injury Model in Adult Zebrafish

  2018cites this paper
• DEVELOPMENTAL EXPOSURE TO DIESEL EXHAUST CAUSES AUTISM-LIKE BEHAVIORAL, MOLECULAR, AND CORTICAL STRUCTURAL ALTERATIONS.

  2018cites this paper
• A Bioengineering Approach Towards Retina Regeneration

  2018cites this paper
• The expression of CKLFSF2B is regulated by GATA1 and CREB in the Leydig cells, which modulates testicular steroidogenesis.

  2018cites this paper
• Radix Scutellariae Attenuates CUMS-Induced Depressive-Like Behavior by Promoting Neurogenesis via cAMP/PKA Pathway

  2018cites this paper
• Walnut diets up-regulate the decreased hippocampal neurogenesis and age-related cognitive dysfunction in d-galactose induced aged rats.

  2018cites this paper
• A Dual Role for Hyperbaric Oxygen in Stroke Neuroprotection: Preconditioning of the Brain and Stem Cells.

  2018influential citation
• CREB controls cortical circuit plasticity and functional recovery after stroke

  2018cites this paper
• Carnosine activates the CREB pathway in Caco-2 cells

  2017cites this paper
• Crosstalk of metabolic factors and neurogenic signaling in adult neurogenesis: Implication of metabolic regulation for mental and neurological diseases.

  2017cites this paper
• Extracellular regulated protein kinaseis critical for the role of 5‐HT1a receptor in modulating nNOS expression and anxiety‐related behaviors

  2017cites this paper
• ZL006 promotes migration and differentiation of transplanted neural stem cells in male rats after stroke

  2017cites this paper
• Canonical Transient Receptor Potential Channels and Their Link with Cardio/Cerebro-Vascular Diseases

  2017cites this paper
• A causal mediation model of ischemia reperfusion injury in the retina

  2017cites this paper
• Histone acetylation of oligodendrocytes protects against white matter injury induced by inflammation and hypoxia-ischemia through activation of BDNF-TrkB signaling pathway in neonatal rats.

  2017cites this paper
• Metabolic Factors and Adult Neurogenesis: Impacts of Chinese Herbal Medicine on Brain Repair in Neurological Diseases.

  2017cites this paper
• Examining the Effects of Anti-Nogo a Immunotherapy on Post-Stroke Neurogenesis in the Adult Rat

  2016influential citation
• CREB-mediated synaptogenesis and neurogenesis is crucial for the role of 5-HT1a receptors in modulating anxiety behaviors

  2016influential citation
• Myeloperoxidase Inhibition Increases Neurogenesis after Ischemic Stroke

  2016cites this paper
• Critical role of astrocytic interleukin-17 A in post-stroke survival and neuronal differentiation of neural precursor cells in adult mice

  2016cites this paper
• Anti-Nogo-A Immunotherapy Does Not Alter Hippocampal Neurogenesis after Stroke in Adult Rats

  2016influential citation
• Cerium oxide nanoparticles promote neurogenesis and abrogate hypoxia-induced memory impairment through AMPK–PKC–CBP signaling cascade

  2016cites this paper
• Protective Effects of Danshen on Cerebral Vessels and the Nervous System

  2015cites this paper
• L‐3‐n‐butylphthalide Promotes Neurogenesis and Neuroplasticity in Cerebral Ischemic Rats

  2015cites this paper
• Mitogen and stress-activated kinases 1/2 regulate ischemia-induced hippocampal progenitor cell proliferation and neurogenesis.

  2015cites this paper
• Inhibition of miR-134 Protects Against Hydrogen Peroxide-Induced Apoptosis in Retinal Ganglion Cells

  2015cites this paper
• Tissue-Specific Progenitor and Stem Cells Phosphodiesterase 7 Inhibition Induces Dopaminergic Neurogenesis in Hemiparkinsonian Rats

  2015cites this paper
• Current Neurogenic and Neuroprotective Strategies to Prevent and Treat Neurodegenerative and Neuropsychiatric Disorders

  2015cites this paper
• Post-Translational Modifications of Histones in Vertebrate Neurogenesis

  2015cites this paper
• Adjuvant Granulocyte Colony-Stimulating Factor Therapy Results in Improved Spatial Learning and Stimulates Hippocampal Neurogenesis in a Mouse Model of Pneumococcal Meningitis

  2015cites this paper
• Neurogenesis and neuroprotection in postischemic brain neurodegeneration with Alzheimer phenotype: is there a role for curcumin?

  2015cites this paper
• Inhibition of MAPK/ERK signaling blocks hippocampal neurogenesis and impairs cognitive performance in prenatally infected neonatal rats

  2015cites this paper
• Neuroprotection by (-)-epigallocatechin-3-gallate in a rat model of stroke is mediated through inhibition of endoplasmic reticulum stress.

  2014cites this paper
• Physical exercise ameliorates the reduction of neural stem cell, cell proliferation and neuroblast differentiation in senescent mice induced by D-galactose

  2014cites this paper
• Convergent and Divergent Pathways Decoding Hierarchical Additive Mechanisms in Treating Cerebral Ischemia–Reperfusion Injury

  2014influential citation
• Therapeutic Intervention of Learning and Memory Decays by Salidroside Stimulation of Neurogenesis in Aging

  2014cites this paper
• Forced limb-use enhances brain plasticity through the cAMP/PKA/CREB signal transduction pathway after stroke in adult rats

  2014cites this paper
• The gep proto-oncogene Gα12 mediates LPA-stimulated activation of CREB in ovarian cancer cells.

  2014cites this paper
• Nuclear Calcium Signaling Induces Expression of the Synaptic Organizers Lrrtm1 and Lrrtm2*

  2014cites this paper
• The interaction between microglia and neural stem/precursor cells.

  2014cites this paper
• Neuronal Activity-Dependent Transcriptional Regulation of the Synaptic Cell Adhesion Molecules Lrrtm1 and Lrrtm2

  2014cites this paper
• The effect of maternal infection on cognitive development and hippocampus neuronal apoptosis, proliferation and differentiation in the neonatal rats.

  2013cites this paper
• Neuroprotective effect of calcitriol on ischemic/reperfusion injury through the NR3A/CREB pathways in the rat hippocampus.

  2013cites this paper
• The Transcriptional Response of Neurotrophins and Their Tyrosine Kinase Receptors in Lumbar Sensorimotor Circuits to Spinal Cord Contusion is Affected by Injury Severity and Survival Time

  2013cites this paper
• Delayed hyperbaric oxygen therapy induces cell proliferation through stabilization of cAMP responsive element binding protein in the rat model of MCAo-induced ischemic brain injury.

  2013cites this paper
• Neuroprotective Effect of Resveratrol on Ischemia/Reperfusion Injury in Rats Through TRPC6/CREB Pathways

  2013influential citation
• Acupuncture stimulation induces neurogenesis in adult brain.

  2013cites this paper
• CREB-mediated Enhancement of Hippocampus-dependent Memory Consolidation and Reconsolidation

  2013cites this paper
• Gene expression analysis of neurotrophins, Trk receptors, and associated regulatory molecules after contusive spinal cord injury.

  2013cites this paper
• Adult neurogenesis in the dentate gyrus

  2013cites this paper
• F3/Contactin promotes hippocampal neurogenesis, synaptic plasticity, and memory in adult mice

  2013cites this paper
• Psychosocial influences on the dynamics of adult hippocampal neurogenesis

  2012cites this paper
• Significant implications of Bcl-2 in the formation of striatonigral projection neurons in the ischemic striatum

  2012cites this paper
• When Things Go Wrong - Diseases and Disorders of the Human Brain

  2012cites this paper
• CREB signalling in neural stem/progenitor cells: Recent developments and the implications for brain tumour biology

  2012cites this paper
• CREB Signaling in Neural Stem/Progenitor Cells: Implications for a Role in Brain Tumors

  2012cites this paper
• Chronic Nicotine Administration Impairs Activation of Cyclic AMP-Response Element Binding Protein and Survival of Newborn Cells in the Dentate Gyrus

  2012influential citation
• Seeing old friends from a different angle: Novel properties of hematopoietic growth factors in the healthy and diseased brain

  2012cites this paper
• The transcriptional response to chronic stress and glucocorticoid receptor blockade in the hippocampal dentate gyrus

  2012cites this paper
• A Signaling Cascade of Nuclear Calcium-CREB-ATF3 Activated by Synaptic NMDA Receptors Defines a Gene Repression Module That Protects against Extrasynaptic NMDA Receptor-Induced Neuronal Cell Death and Ischemic Brain Damage

  2011cites this paper
• Research progress on neurobiology of neuronal nitric oxide synthase

  2011cites this paper
• Hippocampal Telomerase Is Involved in the Modulation of Depressive Behaviors

  2011cites this paper