Plasma choline and betaine and their relation to plasma homocysteine in normal pregnancy.

No abstract is available for this paper.

• Publication year

  2005

• Venue

  American Journal of Clinical Nutrition

• Publication date

  2005-06-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1093/AJCN/81.6.1383PMID 15941891
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Choline and phosphatidylcholine

  2005cited by this paper
• Periconceptional dietary intake of choline and betaine and neural tube defects in offspring.

  2004cited by this paper
• Betaine and Folate Status as Cooperative Determinants of Plasma Homocysteine in Humans

  2004cited by this paper
• Betaine as a Determinant of Postmethionine Load Total Plasma Homocysteine Before and After B-Vitamin Supplementation

  2004influential reference
• Renal Handling of Homocysteine During Normal Pregnancy and Preeclampsia

  2004cited by this paper
• Determination of choline, betaine, and dimethylglycine in plasma by a high-throughput method based on normal-phase chromatography-tandem mass spectrometry.

  2003cited by this paper
• Plasma total homocysteine in uncomplicated pregnancy and in preeclampsia.

  2003cited by this paper
• Homocysteine and other plasma amino acids in preeclampsia and in pregnancies without complications.

  2003cited by this paper
• Homocysteine‐betaine interactions in a murine model of 5,10‐methylenetetrahydrofolate reductase deficiency

  2003cited by this paper
• Free and Phospholipid-Bound Choline Concentrations in Serum during Pregnancy, after Delivery and in Newborns

  2002influential reference
• Longitudinal concentrations of vitamin B(12) and vitamin B(12)-binding proteins during uncomplicated pregnancy.

  2002cited by this paper
• The pregnancy-related decrease in fasting plasma homocysteine is not explained by folic acid supplementation, hemodilution, or a decrease in albumin in a longitudinal study.

  2002cited by this paper
• Longitudinal vitamin and homocysteine levels in normal pregnancy

  2001cited by this paper
• Choline: an essential nutrient for humans.

  2000cited by this paper
• Choline: Needed for Normal Development of Memory

  2000cited by this paper
• Changes in homocysteine levels during normal pregnancy.

  1999cited by this paper
• Interaction between Dietary Methionine and Methyl Donor Intake on Rat Liver Betaine-homocysteine Methyltransferase Gene Expression and Organization of the Human Gene*

  1999cited by this paper
• Homocysteine metabolism.

  1999cited by this paper
• Homocysteine and cardiovascular disease.

  1998cited by this paper
• The relationship between maternal and neonatal umbilical cord plasma homocyst(e)ine suggests a potential role for maternal homocyst(e)ine in fetal metabolism.

  1998cited by this paper
• Plasma Homocyst(e)ine Concentrations in Pregnant and Nonpregnant Women With Controlled Folate Intake

  1998cited by this paper
• Homocysteine and cardiovascular disease

  1996cited by this paper
• Pregnancy and lactation are associated with diminished concentrations of choline and its metabolites in rat liver.

  1995cited by this paper
• Pattern of vitamin B12 and folic acid during pregnancy.

  1994cited by this paper
• Choline and human nutrition.

  1994cited by this paper
• Decreased serum homocysteine in pregnancy.

  1992cited by this paper
• Longitudinal assessment of changes in reproductive hormones during normal pregnancy.

  1991cited by this paper
• Choline, an essential nutrient for humans

  1991cited by this paper
• Placental corticotropin-releasing hormone may be a stimulator of maternal pituitary adrenocorticotropic hormone secretion in humans.

  1989cited by this paper
• The Adrenal Gland

  1988cited by this paper
• [Endocrinology in pregnancy].

  1987cited by this paper
• Total homocyst(e)ine in plasma and amniotic fluid of pregnant women.

  1986cited by this paper
• Evidence of saturable uptake mechanisms at maternal and fetal sides of the perfused human placenta by rapid paired-tracer dilution: studies with calcium and choline.

  1986cited by this paper
• Measurement of free choline concentrations in maternal and neonatal blood by micropyrolysis gas chromatography.

  1985influential reference
• Modern nutrition in health and disease

  1980cited by this paper
• Clinical Physiology in Obstetrics

  1980cited by this paper
• FREE CHOLINE CONCENTRATION AND CEPHALIN‐N‐METHYLTRANSFERASE ACTIVITY IN THE MATERNAL AND FOETAL LIVER AND PLACENTA OF PREGNANT RATS

  1978influential reference
• Studies on accumulation and metabolic fate of (N-Me3h)choline in human term placenta fragments.

  1976cited by this paper
• Methionine metabolism in mammals. Regulation of homocysteine methyltransferases in rat tissue.

  1971cited by this paper
• The Adrenal Gland

  1949cited by this paper
• ESTROGENS AND ANDROGENS

  1943cited by this paper

• Vitamin B12 and Homocysteine in Pregnant Women With Gestational Diabetes Mellitus and Their Association With Obesity.

  2026cites this paper
• Choline in Adolescent Pregnancy: The Impact on Fetal Brain Development and Long-Term Cognitive Outcomes of Offspring

  2025cites this paper
• Methionine in embryonic development: metabolism, redox homeostasis, epigenetic modification and signaling pathway

  2025cites this paper
• Longitudinal Analysis of One-Carbon Metabolism-Related Metabolites in Maternal and Cord Blood of Japanese Pregnant Women

  2024cites this paper
• Supplementing dietary betaine during late gestation increases plasma betaine and methionine concentrations in pregnant Merino ewes but not neonatal lambs

  2024cites this paper
• Biomarker Candidates of Habitual Food Intake in a Swedish Cohort of Pregnant and Lactating Women and Their Infants

  2024cites this paper
• Metabolomic Profiling of Hormonal Contraceptive Use in Young Females Using a Commercially Available LC-MS/MS Kit

  2023cites this paper
• Choline – a scoping review for Nordic Nutrition Recommendations 2023

  2023cites this paper
• Gene expression of cardiovascular risk markers in mononuclear cells of pregnant woman in relation to plasma leptin and homocysteine levels: A cross sectional study

  2023cites this paper
• Trimester-specific reference intervals of serum homocysteine levels for pregnant women: a longitudinal study in China

  2023cites this paper
• Serum 5-Methyltetrahydrofolate Status Is Associated with One-Carbon Metabolism-Related Metabolite Concentrations and Enzyme Activity Indicators in Young Women

  2023cites this paper
• Anthropometric measures and arsenic methylation among pregnant women in rural northern Bangladesh

  2023cites this paper
• Diet- and microbiota-related metabolite, 5-aminovaleric acid betaine (5-AVAB), in health and disease.

  2022cites this paper
• Pregnancy-induced alterations of 1-carbon metabolism and significance for maternal nutrition requirements.

  2022cites this paper
• Homocysteine Metabolism in Pregnancy and Developmental Impacts

  2022cites this paper
• Betaine consumption as a new clinical approach to treatment and prophylaxis of folate-related pathologies.

  2022cites this paper
• Quantitative analysis of the serum proteome during early pregnancy in mares.

  2022cites this paper
• Effects of betaine supplementation on cardiovascular markers: A systematic review and Meta-analysis

  2021cites this paper
• Maternal plasma choline and betaine in late pregnancy and child growth up to age 8 years in the KOALA Birth Cohort Study

  2021cites this paper
• Choline metabolome response to prenatal choline supplementation across pregnancy: A randomized controlled trial

  2021cites this paper
• A Novel Review of Homocysteine and Pregnancy Complications

  2021cites this paper
• Epigenetic landscape of stress surfeit disorders: Key role for DNA methylation dynamics.

  2021cites this paper
• Presence of MTHFR Polymorphisms and the Levels of Folic Acid and Homocysteine in Women Enrolled in an Assisted Reproductive Program

  2020cites this paper
• One Carbon Metabolism and Mammalian Pregnancy Outcomes.

  2020cites this paper
• Effects of maternal and fetal choline concentrations on the fetal growth and placental DNA methylation of 12 target genes related to fetal growth, adipogenesis, and energy metabolism

  2020cites this paper
• Maternal betaine status, but not that of choline or methionine, is inversely associated with infant birth weight

  2019cites this paper
• Serum Betaine and Dimethylglycine Are Higher in South Asian Compared with European Pregnant Women in Canada, with Betaine and Total Homocysteine Inversely Associated in Early and Midpregnancy, Independent of Ethnicity.

  2019cites this paper
• Prospective associations of maternal choline status with offspring body composition in the first 5 years of life in two large mother-offspring cohorts: the Southampton Women's Survey cohort and the Growing Up in Singapore Towards healthy Outcomes cohort.

  2019cites this paper
• The Roles of Choline in Maintaining Optimal Health

  2019cites this paper
• S 2 Appendix : Determinants of plasma homocysteine as ingredients for the novel drink powder supplement

  2019cites this paper
• The Impact of One Carbon Metabolism on Histone Methylation

  2019cites this paper
• Longitudinal Changes of One-Carbon Metabolites and Amino Acid Concentrations during Pregnancy in the Women First Maternal Nutrition Trial

  2019influential citation
• PEMT rs12325817 and PCYT1A rs7639752 polymorphisms are associated with betaine but not choline concentrations in pregnant women.

  2018cites this paper
• Effect of homocysteine on pregnancy: A systematic review.

  2018cites this paper
• Association of serum asymmetric dimethylarginine, homocysteine, and l-arginine concentrations during early pregnancy with hypertensive disorders of pregnancy.

  2017cites this paper
• Dietary choline intake and biomarkers of choline status across the life cycle

  2017influential citation
• Diet and DNA damage in infants: the DADHI study

  2017cites this paper
• Maternal choline status during pregnancy, but not that of betaine, is related to antenatal mental well‐being: The growing up in Singapore toward healthy outcomes cohort

  2017influential citation
• Impact of Pre-Pregnancy BMI on B Vitamin and Inflammatory Status in Early Pregnancy: An Observational Cohort Study

  2016cites this paper
• Examining the essentiality of maternal choline intake during early infant development

  2016cites this paper
• The Pediatric Methionine Requirement Should Incorporate Remethylation Potential and Transmethylation Demands.

  2016cites this paper
• Potential role of folate in pre-eclampsia.

  2015cites this paper
• A prospective study of maternal fatty acids, micronutrients and homocysteine and their association with birth outcome.

  2015cites this paper
• Maternal Choline Status, but Not Fetal Genotype, Influences Cord Plasma Choline Metabolite Concentrations.

  2015influential citation
• Vitamin B12 and Choline Status in a Cohort of Canadian Pregnant Women and their Newborn Infants

  2015influential citation
• Folate, Vitamin B12 and Homocysteine status in the post-folic acid fortification era in different subgroups of the Brazilian population attended to at a public health care center

  2015cites this paper
• Biomarkers of Nutrition for Development-Folate Review.

  2015cites this paper
• Serial determinations of asymmetric dimethylarginine and homocysteine during pregnancy to predict pre‐eclampsia: a longitudinal study

  2015cites this paper
• Availability of arsenic in human milk in women and its correlation with arsenic in urine of breastfed children living in arsenic contaminated areas in Bangladesh

  2014cites this paper
• Egg n-3 fatty acid composition modulates biomarkers of choline metabolism in free-living lacto-ovo-vegetarian women of reproductive age.

  2014cites this paper
• Nutritional effects of betaine on weight and length of rat offspring

  2014cites this paper
• Most blood biomarkers related to vitamin status, one-carbon metabolism, and the kynurenine pathway show adequate preanalytical stability and within-person reproducibility to allow assessment of exposure or nutritional status in healthy women and cardiovascular patients.

  2014cites this paper
• Maternal choline supplementation: a nutritional approach for improving offspring health?

  2014cites this paper
• Availability of arsenic in breast milk, effect of chronic arsenic exposure on type 2 diabetes, hypertension in adults and on children's nutritional status in Bangladesh

  2014cites this paper
• Authorised EU health claims for choline

  2014cites this paper
• Modeling Most Blood Biomarkers Related to Vitamin Status , One-Carbon Metabolism , and the Kynurenine Pathway Show Adequate Preanalytical Stability and Within-Person Reproducibility to Allow Assessment of Exposure or Nutritional Status in Healthy Women and Cardiovascular Patients 1 – 3

  2014cites this paper
• Plasma choline and betaine correlate with serum folate, plasma S-adenosyl-methionine and S-adenosyl-homocysteine in healthy volunteers

  2013cites this paper
• Low plasma vitamin B-12 is associated with a lower pregnancy-associated rise in plasma free choline in Canadian pregnant women and lower postnatal growth rates in their male infants.

  2013cites this paper
• Methyl donor supplementation of gestating sow diets improves pregnancy outcomes and litter size

  2013cites this paper
• Choline metabolism in response to choline intake, pregnancy, and polymorphisms of one-carbon metabolic genes in humans

  2013cites this paper
• Low folate status enhances pregnancy changes in plasma betaine and dimethylglycine concentrations and the association between betaine and homocysteine.

  2013cites this paper
• Elevated dimethylglycine in blood of children with congenital heart defects and their mothers.

  2013cites this paper
• Low folate status enhances pregnancy changes in plasma betaine and dimethylglycine concentrations and the association between betaine

  2013cites this paper
• The Metabolic Burden of Methyl Donor Deficiency with Focus on the Betaine Homocysteine Methyltransferase Pathway

  2013cites this paper
• Developmental epigenetics in humans : can maternal nutritional status mediate DNA methylation in their offspring?

  2013influential citation
• on ‘From plough through practice to policy’ Maternal nutritional status, C 1 metabolism and offspring DNA methylation: a review of current evidence in human subjects

  2012cites this paper
• Maternal choline intake modulates maternal and fetal biomarkers of choline metabolism in humans.

  2012cites this paper
• Maternal homocysteine and small-for-gestational-age offspring: systematic review and meta-analysis.

  2012cites this paper
• Early Second Trimester Maternal Plasma Choline and Betaine Are Related to Measures of Early Cognitive Development in Term Infants

  2012influential citation
• Methionine, homocysteine, one carbon metabolism and fetal growth

  2012cites this paper
• Measuring allostatic load in a nationally representative sample of pregnant women

  2012cites this paper
• Homocistena srica en neonatos de preeclmpticas y de embarazadas normotensas

  2011cites this paper
• Maternal nutritional status, C1 metabolism and offspring DNA methylation: a review of current evidence in human subjects

  2011cites this paper
• Umbilical choline and related methylamines betaine and dimethylglycine in relation to birth weight

  2011cites this paper
• Choline and betaine in health and disease

  2011cites this paper
• Homocysteine in pregnancy.

  2011cites this paper
• Physiologic changes in homocysteine metabolism in pregnancy: a longitudinal study in Spain.

  2011cites this paper
• Determining the role of choline dehydrogenase in sperm cell function

  2011cites this paper
• Pre- and postnatal health: evidence of increased choline needs.

  2010cites this paper
• Choline in health and disease

  2010cites this paper
• The clinical significance of betaine, an osmolyte with a key role in methyl group metabolism.

  2010influential citation
• Age and sex differences in plasma homocysteine, choline and betaine status in Seychellois children and young adults

  2010cites this paper
• Emerging societies : coexistence of childhood malnutrition and obesity

  2009cites this paper
• Choline: an essential nutrient for public health.

  2009cites this paper
• Folate and Choline Interrelationships: Metabolic and Potential Health Implications

  2009cites this paper
• Effects of arsenic on maternal and fetal health.

  2009cites this paper
• Choline and Its Products Acetylcholine and Phosphatidylcholine

  2009cites this paper
• The homocysteine pathway in human subfertility

  2009cites this paper
• Homocysteine metabolism in the pre-ovulatory follicle during ovarian stimulation.

  2008cites this paper
• Choline concentrations in human maternal and cord blood and intelligence a t5yo f age 1-3

  2008cites this paper
• Effects of Folate and Vitamin B12 Deficiencies During Pregnancy on Fetal, Infant, and Child Development

  2008cites this paper
• Genetic polymorphisms in methyl-group metabolism and epigenetics: lessons from humans and mouse models.

  2008cites this paper
• Breast-feeding Protects against Arsenic Exposure in Bangladeshi Infants

  2008cites this paper
• Homocysteine concentration, related B vitamins, and betaine in pregnant women recruited to the Seychelles Child Development Study.

  2008cites this paper
• Choline concentrations in human maternal and cord blood and intelligence at 5 y of age.

  2008cites this paper
• 1H-NMR metabolic profiling of human neonatal urine

  2007cites this paper
• 3.2 Choline and Its Products Acetylcholine and Phosphatidylcholine Choline

  2007cites this paper
• Relationship of dimethylglycine, choline, and betaine with oxoproline in plasma of pregnant women and their newborn infants.

  2007cites this paper
• Homocysteine, Cysteine, and Related Metabolites in Maternal and Fetal Plasma in Preeclampsia

  2007cites this paper
• Nutritional Status Has Marginal Influence on the Metabolism of Inorganic Arsenic in Pregnant Bangladeshi Women

  2007cites this paper