Alpha1-adrenergic receptor signaling is localized to caveolae in neonatal rat cardiomyocytes.

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Journal of Molecular and Cellular Cardiology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 16730745
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Endothelin-1–Induced Arrhythmogenic Ca2+ Signaling Is Abolished in Atrial Myocytes of Inositol-1,4,5-Trisphosphate(IP3)–Receptor Type 2–Deficient Mice

  2005cited by this paper
• G-protein-coupled Receptor Signaling Components Localize in Both Sarcolemmal and Intracellular Caveolin-3-associated Microdomains in Adult Cardiac Myocytes*

  2005cited by this paper
• PIP2 signaling in lipid domains: a critical re‐evaluation

  2005cited by this paper
• Mobility of proteins associated with the plasma membrane by interaction with inositol lipids

  2005cited by this paper
• Impaired KCNQ1–KCNE1 and Phosphatidylinositol-4,5-Bisphosphate Interaction Underlies the Long QT Syndrome

  2005cited by this paper
• Low mobility of phosphatidylinositol 4,5-bisphosphate underlies receptor specificity of Gq-mediated ion channel regulation in atrial myocytes.

  2005cited by this paper
• Human cardiac phospholipase D activity is tightly controlled by phosphatidylinositol 4,5-bisphosphate.

  2004cited by this paper
• Differential Recruitment of Kv1.4 and Kv4.2 to Lipid Rafts by PSD-95*

  2004cited by this paper
• UTP Transactivates Epidermal Growth Factor Receptors and Promotes Cardiomyocyte Hypertrophy Despite Inhibiting Transcription of the Hypertrophic Marker Gene, Atrial Natriuretic Peptide*

  2004cited by this paper
• Do you believe in lipid rafts? Biologists are turning to several analytical techniques to find out whether lipid rafts really exist?

  2004cited by this paper
• The alpha(1A/C)- and alpha(1B)-adrenergic receptors are required for physiological cardiac hypertrophy in the double-knockout mouse.

  2003cited by this paper
• Developmental changes in beta2-adrenergic receptor signaling in ventricular myocytes: the role of Gi proteins and caveolae microdomains.

  2003cited by this paper
• Lymphocyte lipid rafts: structure and function.

  2003cited by this paper
• Lipid Rafts/Caveolae Are Essential for Insulin-like Growth Factor-1 Receptor Signaling during 3T3-L1 Preadipocyte Differentiation Induction*

  2003cited by this paper
• Endothelin-1 activates mesangial cell ERK1/2 via EGF-receptor transactivation and caveolin-1 interaction.

  2003cited by this paper
• Caveolae-associated proteins in cardiomyocytes: caveolin-2 expression and interactions with caveolin-3.

  2003cited by this paper
• Akt-mediated Cardiomyocyte Survival Pathways Are Compromised by Gαq-induced Phosphoinositide 4,5-Bisphosphate Depletion*

  2003cited by this paper
• Cholesterol levels modulate EGF receptor-mediated signaling by altering receptor function and trafficking.

  2002cited by this paper
• Inositol Polyphosphate 1-Phosphatase Is a Novel Antihypertrophic Factor*

  2002cited by this paper
• Alpha1-adrenoceptor-mediated breakdown of phosphatidylinositol 4,5-bisphosphate inhibits pinacidil-activated ATP-sensitive K+ currents in rat ventricular myocytes.

  2002cited by this paper
• The TRPM7 channel is inactivated by PIP2 hydrolysis

  2002cited by this paper
• Signaling microdomains define the specificity of receptor-mediated InsP(3) pathways in neurons.

  2002cited by this paper
• Cholesterol Depletion from the Plasma Membrane Triggers Ligand-independent Activation of the Epidermal Growth Factor Receptor*

  2002cited by this paper
• Modulation of cardiac PIP2 by cardioactive hormones and other physiologically relevant interventions.

  2002cited by this paper
• Signalling and non-caveolar rafts.

  2001cited by this paper
• Evidence for selective coupling of alpha 1-adrenergic receptors to phospholipase C-beta 1 in rat neonatal cardiomyocytes.

  2001cited by this paper
• Depletion of Phosphatidylinositol 4,5-Bisphosphate by Activation of Phospholipase C-coupled Receptors Causes Slow Inhibition but Not Desensitization of G Protein-gated Inward Rectifier K+ Current in Atrial Myocytes*

  2001cited by this paper
• Accumulation of molecules involved in alpha1-adrenergic signal within caveolae: caveolin expression and the development of cardiac hypertrophy.

  2001cited by this paper
• The conserved phosphoinositide 3‐kinase pathway determines heart size in mice

  2000cited by this paper
• Membrane cytoskeleton: PIP(2) pulls the strings.

  2000cited by this paper
• PIP2 and PIP3: complex roles at the cell surface.

  2000cited by this paper
• Differential targeting of beta -adrenergic receptor subtypes and adenylyl cyclase to cardiomyocyte caveolae. A mechanism to functionally regulate the cAMP signaling pathway.

  2000cited by this paper
• The type II PIPkins (PtdIns5P 4-kinases): enzymes in search of a function?

  1999cited by this paper
• Activated protein kinase C isoforms target to cardiomyocyte caveolae : stimulation of local protein phosphorylation.

  1999cited by this paper
• Modification of the Laemmli sodium dodecyl sulfate-polyacrylamide gel electrophoresis procedure to eliminate artifacts on reducing and nonreducing gels.

  1997cited by this paper
• Regulation of Cardiac Na+,Ca2+ Exchange and KATP Potassium Channels by PIP2

  1996cited by this paper
• Rho is required for Galphaq and alpha1-adrenergic receptor signaling in cardiomyocytes. Dissociation of Ras and Rho pathways.

  1996cited by this paper
• Phosphoinositide kinases.

  1996cited by this paper
• The inositol phosphate response to thrombin in rat right atria differs from the response to noradrenaline.

  1995cited by this paper
• Suppression of ventricular arrhythmias during ischemia-reperfusion by agents inhibiting Ins(1,4,5)P3 release.

  1995cited by this paper
• Inositol phosphate release and metabolism in rat left atria.

  1995cited by this paper
• Two forms of phospholipase C-beta 1 generated by alternative splicing.

  1994cited by this paper
• Proteolytic modification of membrane-associated phospholipase C-beta by mu-calpain enhances its activation by G-protein beta gamma subunits in human platelets.

  1994cited by this paper
• Endothelin stimulates phosphatidylinositol turnover in rat right and left atria.

  1990cited by this paper

• Phthalate monoesters affect membrane fluidity and cell-cell contacts in endometrial stromal adherent cell lines and spheroids.

  2024cites this paper
• Sur7 mediates a novel pathway for PI4,5P2 regulation in C. albicans that promotes stress resistance and cell wall morphogenesis

  2024cites this paper
• Cholesterol and PIP2 Modulation of BKCa Channels.

  2023cites this paper
• Physiological functions of caveolae in endothelium.

  2023cites this paper
• Novel Smooth Muscle Ca2+-Signaling Nanodomains in Blood Pressure Regulation

  2022cites this paper
• Lipid rafts in psychiatry.

  2019cites this paper
• Interaction Between Pannexin 1 and Caveolin-1 in Smooth Muscle Can Regulate Blood Pressure

  2018cites this paper
• Changes in the plasma membrane in metabolic disease: impact of the membrane environment on G protein‐coupled receptor structure and function

  2018cites this paper
• Caveolin 1 Promotes Renal Water and Salt Reabsorption

  2018cites this paper
• Myocyte membrane and microdomain modifications in diabetes: determinants of ischemic tolerance and cardioprotection

  2017cites this paper
• Sarcolemmal dependence of cardiac protection and stress‐resistance: roles in aged or diseased hearts

  2016cites this paper
• Studying GPCR/cAMP pharmacology from the perspective of cellular structure

  2015cites this paper
• Identification of Caveolar Resident Proteins in Ventricular Myocytes Using a Quantitative Proteomic Approach: Dynamic Changes in Caveolar Composition Following Adrenoceptor Activation

  2015cites this paper
• A dPIP5K Dependent Pool of Phosphatidylinositol 4,5 Bisphosphate (PIP2) Is Required for G-Protein Coupled Signal Transduction in Drosophila Photoreceptors

  2015cites this paper
• Cardiac Alpha1-Adrenergic Receptors: Novel Aspects of Expression, Signaling Mechanisms, Physiologic Function, and Clinical Importance

  2014cites this paper
• The Phosphatidylinositol(4,5)Bisphosphate–Binding Sequence of Transient Receptor Potential Channel Canonical 4α Is Critical for Its Contribution to Cardiomyocyte Hypertrophy

  2014influential citation
• An association of metabolic syndrome constellation with cellular membrane caveolae

  2014cites this paper
• Differences in the Signaling Pathways of α1A- and α1B-Adrenoceptors Are Related to Different Endosomal Targeting

  2013cites this paper
• A Role for G-Proteins in Directing G-Protein-Coupled Receptor–Caveolae Localization

  2012cites this paper
• RhoA localization with caveolin-1 regulates vascular contractions to serotonin.

  2012cites this paper
• Phosphatidylinositol 4, 5 bisphosphate and the actin cytoskeleton.

  2012cites this paper
• Caveolae create local signalling domains through their distinct protein content, lipid profile and morphology.

  2012influential citation
• Phospholipase Cβlb associates with a Shank3 complex at the cardiac sarcolemma

  2011cites this paper
• Role of caveolin-1 in brown adipose tissue

  2010cites this paper
• Caveolae Contribute to the Apoptosis Resistance Induced by the α1A-Adrenoceptor in Androgen-Independent Prostate Cancer Cells

  2009cites this paper
• Lipid rafts constrain basal alpha(1A)-adrenergic receptor signaling by maintaining receptor in an inactive conformation.

  2009cites this paper
• Adenosine A(1) receptors selectively target protein kinase C isoforms to the caveolin-rich plasma membrane in cardiac myocytes.

  2009cites this paper
• Gq‐initiated cardiomyocyte hypertrophy is mediated by phospholipase Cβ1b

  2009cites this paper
• Caveolae, ion channels and cardiac arrhythmias.

  2008cites this paper
• The regulation of the cardiac potassium channel (HERG) by caveolin-1.

  2008cites this paper
• The α1a-Adrenergic Receptor Occupies Membrane Rafts with Its G Protein Effectors but Internalizes via Clathrin-coated Pits*

  2008cites this paper
• Novel regulatory mechanisms of D1 dopamine receptor maturation and internalization.

  2008cites this paper
• The role of phosphatidylinositol metabolism and actin in polarized biosynthetic traffic

  2008influential citation
• Nuclear α1-Adrenergic Receptors Signal Activated ERK Localization to Caveolae in Adult Cardiac Myocytes

  2008cites this paper
• The extreme C‐terminal region of phospholipase Cβ1 determines subcellular localization and function; the “b” splice variant mediates α1‐adrenergic receptor responses in cardiomyocytes

  2008cites this paper
• Regulation of the actin cytoskeleton by phosphatidylinositol 4-phosphate 5 kinases

  2007cites this paper
• Arterial remodeling and plasma volume expansion in caveolin-1-deficient mice.

  2007cites this paper
• Dual control of cardiac Na+–Ca2+ exchange by PIP2: electrophysiological analysis of direct and indirect mechanisms

  2007cites this paper
• On the physiological roles of PIP2 at cardiac Na+–Ca2+ exchangers and KATP channels: a long journey from membrane biophysics into cell biology

  2007cites this paper
• N − 3 PUFAs modulate global gene expression profile in cultured rat cardiomyocytes. Implications in cardiac hypertrophy and heart failure

  2007cites this paper
• Local PIP(2) signals: when, where, and how?

  2007cites this paper
• Increased Rho activation and PKC-mediated smooth muscle contractility in the absence of caveolin-1.

  2006cites this paper