Junctional Adhesion Molecule-C Regulates the Early Influx of Leukocytes into Tissues during Inflammation1

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Journal of Immunology

• Publication date

  2005-05-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.4049/jimmunol.174.10.6406PMID 15879142
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2004influential reference
• DNAM-1 and PVR Regulate Monocyte Migration through Endothelial Junctions

  2004cited by this paper
• Junctional adhesion molecules (JAMs): more molecules with dual functions?

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• Adhesion mechanisms regulating the migration of monocytes

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• JAM-C is a component of desmosomes and a ligand for CD11b/CD18-mediated neutrophil transepithelial migration.

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• Coordinated Redistribution of Leukocyte LFA-1 and Endothelial Cell ICAM-1 Accompany Neutrophil Transmigration

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• Locomotion of monocytes on endothelium is a critical step during extravasation

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• P‐selectin mediates IL‐13‐induced eosinophil transmigration but not eotaxin generation in vivo: a comparative study with IL‐4‐elicited responses

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• Overlapping roles of endothelial selectins and vascular cell adhesion molecule-1 in immune complex-induced leukocyte recruitment in the cremasteric microvasculature.

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• Leukocyte trans-endothelial migration: JAMs add new pieces to the puzzle

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• Targeted recycling of PECAM from endothelial surface-connected compartments during diapedesis

  2003cited by this paper
• Leukocyte-endothelial-cell interactions in leukocyte transmigration and the inflammatory response.

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• Blood monocytes consist of two principal subsets with distinct migratory properties.

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• Monocytes Are Potent Facilitators of Alveolar Neutrophil Emigration During Lung Inflammation: Role of the CCL2-CCR2 Axis1

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• Rapid recruitment of inflammatory monocytes is independent of neutrophil migration.

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• The role of CC chemokine receptor 2 in alveolar monocyte and neutrophil immigration in intact mice.

  2002cited by this paper
• JAM2 interacts with alpha4beta1. Facilitation by JAM3.

  2002cited by this paper
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  2002cited by this paper
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  2002influential reference
• CD99 plays a major role in the migration of monocytes through endothelial junctions

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  2001influential reference
• JAM-2, a Novel Immunoglobulin Superfamily Molecule, Expressed by Endothelial and Lymphatic Cells*

  2001influential reference
• Platelet-endothelial cell adhesion molecule-1 (PECAM-1)-deficient mice demonstrate a transient and cytokine-specific role for PECAM-1 in leukocyte migration through the perivascular basement membrane.

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• The parting of the endothelium: miracle, or simply a junctional affair?

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  2000cited by this paper
• CD11/CD18-dependent and -independent neutrophil emigration in the lungs: how do neutrophils know which route to take?

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• Cutting edge: combined treatment of TNF-alpha and IFN-gamma causes redistribution of junctional adhesion molecule in human endothelial cells.

  1999cited by this paper
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  1998cited by this paper
• Neutrophils Emigrate from Venules by a Transendothelial Cell Pathway in Response to FMLP

  1998cited by this paper
• Uniform vascular-endothelial-cell-specific gene expression in both embryonic and adult transgenic mice.

  1997influential reference
• Neutrophil Emigration in the Skin, Lungs, and Peritoneum: Different Requirements for CD11/CD18 Revealed by CD18-deficient Mice

  1997cited by this paper
• Role of the intercellular adhesion molecule-1(ICAM-1) in endotoxin-induced pneumonia evaluated using ICAM-1 antisense oligonucleotides, anti-ICAM-1 monoclonal antibodies, and ICAM-1 mutant mice.

  1996cited by this paper
• P-selectin/ICAM-1 double mutant mice: acute emigration of neutrophils into the peritoneum is completely absent but is normal into pulmonary alveoli.

  1995cited by this paper
• The adhesion molecules used by monocytes for migration across endothelium include CD11a/CD18, CD11b/CD18, and VLA-4 on monocytes and ICAM-1, VCAM-1, and other ligands on endothelium.

  1995cited by this paper
• PECAM-1 is required for transendothelial migration of leukocytes

  1993cited by this paper
• Adhesion receptors of the immune system

  1990cited by this paper
• Hemostasis, Thrombosis, and Vascular Biology Table 1. Inhibition of Vap-1/ssao and Total Mao Enzyme Activity by Hydroxylamine, Semicarbazide, and Btt-2027

  year unknowncited by this paper

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• Leukocyte transendothelial migration hotspots at a glance.

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  2023cites this paper
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  2022cites this paper
• The Roles of Junctional Adhesion Molecules (JAMs) in Cell Migration

  2022cites this paper
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  2021cites this paper
• Regulatory mechanisms of neutrophil migration from the circulation to the airspace

  2021cites this paper
• Neutrophil transendothelial migration hotspots - mechanisms and implications.

  2021cites this paper
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  2020cites this paper
• Exosomal miR-146a-5p from Treponema pallidum-stimulated macrophages reduces endothelial cells permeability and monocyte transendothelial migration by targeting JAM-C.

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  2020cites this paper
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  2019cites this paper
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  2019cites this paper
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  2013cites this paper
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• Junctional adhesion molecule-C (JAM-C) regulates polarized neutrophil transendothelial cell migration in vivo

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• On, around, and through: neutrophil-endothelial interactions in innate immunity.

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• Infection Streptococcus pneumoniae Lungs during Roles in Neutrophil and T Cell Recruitment to Perform Crucial 1 β 4 α

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• A novel function of junctional adhesion molecule-C in mediating melanoma cell metastasis.

  2011cites this paper
• Cancer dissemination--lessons from leukocytes.

  2010cites this paper
• CD99 and CD99L2 act at the same site as, but independently of, PECAM-1 during leukocyte diapedesis.

  2010cites this paper
• Recent developments and complexities in neutrophil transmigration

  2010cites this paper
• Leukocyte transmigration across the blood-brain barrier: perspectives on neuroAIDS.

  2010cites this paper
• Interactions of Leukocytes with the Endothelium

  2010cites this paper
• Junctional Adhesion Molecules (JAMs)

  2010cites this paper
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  2009cites this paper
• Leukocyte – endothelial interactions in inflammation

  2009cites this paper
• Endothelial signaling in paracellular and transcellular leukocyte transmigration.

  2009cites this paper
• Genetic deletion of JAM-C reveals a role in myeloid progenitor generation.

  2009cites this paper
• Junctional Adhesion Molecule–C Mediates Leukocyte Infiltration in Response to Ischemia Reperfusion Injury

  2009cites this paper
• Adaptive Immune Response in JAM-C-Deficient Mice: Normal Initiation but Reduced IgG Memory1

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  2009cites this paper
• Endothelial cell activation leads to neutrophil transmigration as supported by the sequential roles of ICAM-2, JAM-A, and PECAM-1.

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• Role of GM-CSF signaling in cell-based tumor immunization.

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  2009cites this paper
• Junctional adhesion molecule (JAM)‐B supports lymphocyte rolling and adhesion through interaction with α4β1 integrin

  2009cites this paper
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  2009cites this paper
• Role of Junctional Adhesion Molecule-Like Protein in Mediating Monocyte Transendothelial Migration

  2009cites this paper
• Transepithelial migration of neutrophils: mechanisms and implications for acute lung injury.

  2009cites this paper
• Mechanisms of neutrophil transendothelial migration.

  2009influential citation
• Nepmucin/CLM‐9, an Ig domain‐containing sialomucin in vascular endothelial cells, promotes lymphocyte transendothelial migration in vitro

  2008cites this paper
• Evidence for cross‐reactivity of JAM‐C antibodies: implications for cellular localization studies

  2008cites this paper
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  2008influential citation
• Leçons des souris knock-out

  2008cites this paper
• Vascular and epithelial junctions: a barrier for leucocyte migration.

  2008cites this paper
• [JAM-C, adhesion molecule or intercellular junctional organizer: lessons from knock-out mice].

  2008cites this paper
• Brain Endothelial Cell-Cell Junctions: How to “Open” the Blood Brain Barrier

  2008cites this paper
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  2008cites this paper
• The role of junctional adhesion molecules in vascular inflammation

  2007cites this paper
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  2007cites this paper
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  2007cites this paper
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  2007cites this paper
• Regulation of vascular endothelial permeability by junctional adhesion molecules (JAM)

  2007cites this paper
• Lung dendritic cells elicited by Fms-like tyrosine 3-kinase ligand amplify the lung inflammatory response to lipopolysaccharide.

  2007cites this paper
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  2007cites this paper
• JAM family and related proteins in leukocyte migration (Vestweber series).

  2007cites this paper
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  2007cites this paper