Thrombolysis of cerebral clot embolism in rat: effect of treatment delay.

No abstract is available for this paper.

• Publication year

  1999

• Venue

  NeuroReport

• Publication date

  1999-11-08

• Fields of study

  Medicine

• Identifiers
  DOI 10.1097/00001756-199911080-00004PMID 10599832
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Brain hemorrhages after rt-PA treatment of embolic stroke in spontaneously hypertensive rats.

  1999cited by this paper
• Intravenous thrombolytic therapy for acute ischemic stroke. Weighing the risks and benefits of tissue plasminogen activator.

  1998cited by this paper
• Reperfusion after Thrombolytic Therapy of Embolic Stroke in the Rat: Magnetic Resonance and Biochemical Imaging

  1998cited by this paper
• Diffusion-, T2-, and Perfusion-Weighted Nuclear Magnetic Resonance Imaging of Middle Cerebral Artery Embolic Stroke and Recombinant Tissue Plasminogen Activator Intervention in the Rat

  1998cited by this paper
• REPERFUSION OF THE BRAIN AFTER GLOBAL ISCHEMIA: HEMODYNAMIC DISTURBANCES

  1997cited by this paper
• Acute stroke: usefulness of early CT findings before thrombolytic therapy.

  1997cited by this paper
• Activation of complement by tissue plasminogen activator, but not acute cerebral ischemia, in a rabbit model of thromboembolic stroke.

  1997cited by this paper
• Thrombolytic therapy in acute ischaemic stroke: the jury needs more evidence.

  1997cited by this paper
• Improved Perfusion with rt-PA and Hirulog in a Rabbit Model of Embolic Stroke

  1997cited by this paper
• Improved model of thromboembolic stroke and rt-PA induced reperfusion in the rat.

  1997cited by this paper
• Acute hypertension, but not thrombolysis, increases the incidence and severity of hemorrhagic transformation following experimental stroke in rabbits.

  1996cited by this paper
• Evolution of acute focal cerebral ischaemia in rats observed by localized 1H MRS, diffusion‐weighted MRI, and electrophysiological monitoring

  1995cited by this paper
• Monoclonal antibodies preventing leukocyte activation reduce experimental neurologic injury and enhance efficacy of thrombolytic therapy

  1995cited by this paper
• Tissue plasminogen activator for acute ischemic stroke.

  1995cited by this paper
• Evolution of Regional Changes in Apparent Diffusion Coefficient during Focal Ischemia of Rat Brain: The Relationship of Quantitative Diffusion NMR Imaging to Reduction in Cerebral Blood Flow and Metabolic Disturbances

  1995cited by this paper
• Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke. The European Cooperative Acute Stroke Study (ECASS)

  1995cited by this paper
• Effect of Delayed Thrombolysis with rt-PA in a Rat Embolic Stroke Model

  1994cited by this paper
• Reocclusion after thrombolytic therapy: strategies for inhibiting thrombin-induced platelet aggregation.

  1993cited by this paper
• Enhancing the efficacy of thrombolysis by AMPA receptor blockade with NBQX in a rat embolic stroke model.

  1993cited by this paper
• Neuroprotection with NBQX and thrombolysis with rt-PA in rat embolic stroke.

  1993cited by this paper
• Reocclusion after thrombolytic therapy: strategies for inhibiting thrombin-induced platelet aggregation.

  1993cited by this paper
• Diffusion-weighted MR imaging of acute stroke: correlation with T2-weighted and magnetic susceptibility-enhanced MR imaging in cats.

  1990cited by this paper
• Incidence of cerebral hemorrhage after treatment with tissue plasminogen activator or streptokinase following embolic stroke in rabbits [corrected].

  1990cited by this paper
• Fatal ischaemic brain oedema after early thrombolysis with tissue plasminogen activator in acute stroke.

  1988cited by this paper
• MR imaging of intravoxel incoherent motions: application to diffusion and perfusion in neurologic disorders.

  1986cited by this paper

• New insights into acute ischemic stroke from the perspective of spatial omics

  2025cites this paper
• The transient intraluminal filament Middle Cerebral Artery Occlusion stroke model in rats. A step by step guide and technical considerations.

  2022cites this paper
• Animal Models for Ischemic Stroke

  2017cites this paper
• Thromboembolic Model of Cerebral Ischemia and Reperfusion in Mice.

  2016cites this paper
• Animal models of ischemic stroke and their application in clinical research

  2015cites this paper
• Animal models of ischemic stroke and their application in clinical research

  2015cites this paper
• Altersabhängige Mikrogliaaktivierung und Proliferation nach Schlaganfall

  2014cites this paper
• Promoting stroke recovery using delayed growth factor delivery: Contribution of ipsilesional versus contralesional pyramidal tract plasticity

  2014cites this paper
• Rodent models of ischemic stroke lack translational relevance… are baboon models the answer?

  2014cites this paper
• Interazione tra Catestatina e fibre Orexinergiche/NMDAergiche in condizioni simil-ischemiche nel criceto ibernante

  2014cites this paper
• Blood-brain barrier leakage after transient cerebral ischemia

  2014cites this paper
• AFTER TRANSIENT CEREBRAL ISCHEMIA

  2014cites this paper
• Caractérisation par IRM précoce de la synergie tPA - inhibiteur du TAFI dans un modèle d'ischémie focale thromboembolique murin

  2013cites this paper
• Experimental Models of Brain Ischemia: A Review of Techniques, Magnetic Resonance Imaging, and Investigational Cell-Based Therapies

  2013cites this paper
• Etiology of Stroke and Choice of Models

  2012cites this paper
• Insights Into the Development and Treatment of Cardiovascular Disease: A Role for Animal Models

  2010cites this paper
• Animal Models of Ischemic Stroke. Part Two: Modeling Cerebral Ischemia

  2010cites this paper
• Animal models of ischemic stroke.

  2009cites this paper
• La protéine disulfide isomérase et l'ischémie reperfusion cérébrale: une voie de neuroprotection?

  2009cites this paper
• New Targets of Neuroprotection in Ischemic Stroke

  2008cites this paper
• Estudio de los mecanismos moleculares implicados en la muerte apoptótica en un modelo de isquemia cerebral in vitro

  2008cites this paper
• Pharmacological approaches to acute ischaemic stroke: reperfusion certainly, neuroprotection possibly

  2008cites this paper
• Rodent models of ischemic stroke: a useful tool for stroke drug development.

  2008cites this paper
• Acute ischemic stroke: overview of major experimental rodent models, pathophysiology, and therapy of focal cerebral ischemia.

  2007cites this paper
• Therapy of stroke – from experimental studies to clinical trials

  2007cites this paper
• Insights from Experimental Studies

  2006cites this paper
• Thrombolysis and Neuroprotection in Cerebral Ischemia

  2006cites this paper
• Therapeutic strategies for the treatment of stroke.

  2006cites this paper
• Pathophysiology and Therapy of Experimental Stroke

  2006cites this paper
• Neuroprotection – STAIR-Way to the Future?

  2006cites this paper
• Magnetic resonance imaging in ischemic stroke

  2006cites this paper
• N‐Acetylaspartate: a literature review of animal research on brain ischaemia

  2004cites this paper
• The natural course of lesion development in brain ischemia.

  2004cites this paper
• Mechanisms of Secondary Brain Damage from Trauma and Ischemia

  2004cites this paper
• Lesion evolution in cerebral ischemia

  2004cites this paper
• Animal models of stroke: do they have value for discovering neuroprotective agents?

  2003cites this paper
• Nitrones as neuroprotective agents in cerebral ischemia, with particular reference to NXY-059.

  2003cites this paper
• Prediction of Hemorrhagic Transformation After Thrombolytic Therapy of Clot Embolism: An MRI Investigation in Rat Brain

  2002cites this paper
• Thrombolytic Treatment of Clot Embolism in Rat: Comparison of Intra-arterial and Intravenous Application of Recombinant Tissue Plasminogen Activator

  2002cites this paper
• Magnetic Resonance Angiography of Thromboembolic Stroke in Rats: Indicator of Recanalization Probability and Tissue Survival after Recombinant Tissue Plasminogen Activator Treatment

  2002cites this paper
• Why do neuroprotective drugs that are so promising in animals fail in the clinic? An industry perspective

  2002cites this paper
• Effect of NXY‐059 on infarct volume after transient or permanent middle cerebral artery occlusion in the rat; studies on dose, plasma concentration and therapeutic time window

  2002influential citation
• Protocol of a Thromboembolic Stroke Model in the Rat: Review of the Experimental Procedure and Comparison of Models

  2002cites this paper
• Experimentelle Pathophysiologie zerebraler Durchblutungsstörungen

  2001cites this paper
• Early thrombolysis inhibits peri-infarct depolarizations in embolic MCA occlusion

  2001cites this paper
• Application of magnetic resonance to animal models of cerebral ischemia

  2001cites this paper
• Probability of Metabolic Tissue Recovery after Thrombolytic Treatment of Experimental Stroke: A Magnetic Resonance Spectroscopic Imaging Study in Rat Brain

  2000cites this paper
• Functional Differentiation of Multiple Perilesional Zones after Focal Cerebral Ischemia

  2000cites this paper