Adjunctive Bright Light Therapy for Bipolar Depression: A Randomized Double-Blind Placebo-Controlled Trial.

No abstract is available for this paper.

• Publication year

  2017

• Venue

  American Journal of Psychiatry

• Publication date

  2017-10-03

• Fields of study

  Medicine, Psychology

• Identifiers
  DOI 10.1176/appi.ajp.2017.16101200PMID 28969438
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Efficacy of Bright Light Treatment, Fluoxetine, and the Combination in Patients With Nonseasonal Major Depressive Disorder: A Randomized Clinical Trial.

  2016cited by this paper
• Canadian Consensus Guidelines For The Treatment Of Seasonal Affective Disorder

  2016cited by this paper
• Suicidal ideation in depressed postpartum women: Associations with childhood trauma, sleep disturbance and anxiety.

  2015cited by this paper
• Rapid treatment response of suicidal symptoms to lithium, sleep deprivation, and light therapy (chronotherapeutics) in drug-resistant bipolar depression.

  2014cited by this paper
• Outpatient triple chronotherapy for bipolar depression: case report.

  2012cited by this paper
• Controlled trial of safety and efficacy of bright light therapy vs. negative air ions in patients with bipolar depression.

  2012cited by this paper
• Rapid and sustained antidepressant response with sleep deprivation and chronotherapy in bipolar disorder.

  2009cited by this paper
• Lifetime and 12-month prevalence of bipolar spectrum disorder in the National Comorbidity Survey replication.

  2007cited by this paper
• Effectiveness of adjunctive antidepressant treatment for bipolar depression.

  2007cited by this paper
• Light therapy for bipolar disorder: a case series in women.

  2007influential reference
• Mood switch in bipolar depression: comparison of adjunctive venlafaxine, bupropion and sertraline

  2006cited by this paper
• Predictors of recurrence in bipolar disorder: primary outcomes from the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD).

  2006cited by this paper
• The circadian basis of winter depression.

  2006cited by this paper
• Light Treatment for Sleep Disorders : Consensus Report . IV . Sleep Phase and Duration Disturbances

  2006cited by this paper
• Clinical implications of Brief Psychiatric Rating Scale scores.

  2005cited by this paper
• Circadian time of morning light administration and therapeutic response in winter depression.

  2001cited by this paper
• Action Spectrum for Melatonin Regulation in Humans: Evidence for a Novel Circadian Photoreceptor

  2001cited by this paper
• A controlled trial of timed bright light and negative air ionization for treatment of winter depression.

  1998influential reference
• Structured Clinical Interview for DSM-IV Axis I Disorders

  1997cited by this paper
• Midday exposure to bright light changes the circadian organization of plasma melatonin rhythm in humans.

  1997cited by this paper
• Predictors of response and nonresponse to light treatment for winter depression.

  1996cited by this paper
• Light therapy in patients with rapid cycling bipolar disorder: preliminary results.

  1995cited by this paper
• Light therapy in seasonal affective disorder is independent of time of day or circadian phase.

  1993cited by this paper
• Treatment of seasonal affective disorder with green light and red light.

  1991cited by this paper
• Light therapy for seasonal affective disorder. A review of efficacy.

  1989cited by this paper
• The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research.

  1989influential reference
• Assessment of suicidal intention: the Scale for Suicide Ideation.

  1979cited by this paper
• A self-assessment questionnaire to determine morningness-eveningness in human circadian rhythms.

  1976influential reference
• The Journal of Clinical Endocrinology & Metabolism Printed in U.S.A. Copyright © 2001 by The Endocrine Society Diminished Melatonin Secretion in the Elderly Caused by Insufficient Environmental Illumination*

  year unknowninfluential reference

• Circadian rhythm disruption in bipolar disorder: Mechanisms, clinical significance, and rhythm-oriented interventions

  2026cites this paper
• The effect of bright light therapy on glycemic control and cortisol rhythmicity in depression: a randomized controlled trial.

  2026cites this paper
• The placebo effect on depressive symptoms and brain age in patients with depression: a reanalysis study of a randomized controlled clinical trial on the antidepressive effect of bright light therapy.

  2026cites this paper
• The association between sleep onset time and depression among U.S. adults: a cross-sectional study from NHANES 2015–2020

  2025cites this paper
• Circadian Regulation of Neuronal Membrane Capacitance—Mechanisms and Implications for Neural Computation and Behavior

  2025cites this paper
• Interaction of daytime and nighttime light exposure on objective sleep quality in patients with bipolar disorder: a cross-sectional analysis of the APPLE cohort

  2025cites this paper
• Molecular pathways linking the serotonin transporters (SERT) to depressive disorder: from mechanisms to treatments.

  2025cites this paper
• Light therapy for bipolar disorders: Clinical recommendations from the international society for bipolar disorders (ISBD) Chronobiology and Chronotherapy Task Force

  2025influential citation
• Smartphone-Based Bioelectric Coherence Index for Mental Health Diagnostics: A Digital Twin Study

  2025cites this paper
• Lightbox therapy for college students’ depressive symptoms: a pilot study

  2025cites this paper
• Efficiency evaluation and facial expressions biomarker of light therapy in youths with subthreshold depression: A randomized control trial study.

  2025cites this paper
• Stuck in time: The slow march of circadian medicine and how to speed it up

  2025cites this paper
• Chronobiologic treatments for mood disorders.

  2025cites this paper
• Irregular sleep-wake rhythm disorder: From the pathophysiologic perspective to the treatment.

  2025cites this paper
• Effectiveness of bright light therapy in patients suffering from unipolar or bipolar depression; a naturalistic study

  2025cites this paper
• Collecting, detecting, and handling non-wear intervals in longitudinal light exposure data

  2025cites this paper
• Light-eye-body axis: exploring the network from retinal illumination to systemic regulation

  2025cites this paper
• Sleep and psychiatric disorders: Bidirectional interactions and shared neurobiological mechanisms

  2025cites this paper
• Adjunctive bright light therapy to enhance continuous positive airway pressure adherence in patients with comorbid major depressive disorder and obstructive sleep apnoea syndrome: study protocol for a randomised sham-controlled trial

  2025cites this paper
• An intricate relationship between circadian rhythm dysfunction and psychiatric diseases

  2024cites this paper
• A pre-post trial to examine biological mechanisms of the effects of time-restricted eating on symptoms and quality of life in bipolar disorder

  2024cites this paper
• Bright Light Therapy for Nonseasonal Depressive Disorders: A Systematic Review and Meta-Analysis.

  2024cites this paper
• Photobiomodulation therapy mitigates depressive-like behaviors by remodeling synaptic links and mitochondrial function.

  2024cites this paper
• Environmental Bright Light Exposure, Depression Symptoms, and Sleep Regularity

  2024cites this paper
• A randomized controlled trial to compare the effects of time-restricted eating versus Mediterranean diet on symptoms and quality of life in bipolar disorder

  2024cites this paper
• Bright Light Therapy as Add-On to Inpatient Treatment in Youth With Moderate to Severe Depression: A Randomized Clinical Trial.

  2024cites this paper
• Effects of light therapy on sleep and circadian rhythm in older type 2 diabetics living in long-term care facilities: a randomized controlled trial

  2024cites this paper
• The Effect of Light on Negative Emotion and Cognitive Regulation in Individuals with Depressive Tendencies

  2024cites this paper
• Bright Light Therapy for Major Depressive Disorder in Adolescent Outpatients: A Preliminary Study

  2024influential citation
• Microbiota–gut–brain axis mechanisms in the complex network of bipolar disorders: potential clinical implications and translational opportunities

  2023cites this paper
• Delivery of bright light therapy within the veterans health administration.

  2023cites this paper
• Increased volume of the left hippocampal dentate gyrus after 4 weeks of bright light exposure in patients with mood disorders: a randomized controlled study

  2023cites this paper
• A reply to Sit et al.

  2023cites this paper
• Illuminating the way: the role of bright light therapy in the treatment of depression

  2023cites this paper
• 35 years of light treatment for mental disorders in the Netherlands

  2023cites this paper
• Bright light treatment counteracts stress-induced sleep alterations in mice, via a visual circuit related to the rostromedial tegmental nucleus

  2023cites this paper
• Prophylactic Management of Women With Bipolar Disorder During Pregnancy and the Perinatal Period

  2023cites this paper
• Light Therapy for Adolescent Depression: A Scoping Review

  2023cites this paper
• Bipolar Disorder, Circadian Rhythm and Clock Genes

  2023cites this paper
• Adolescent Nonpharmacological Interventions for Early-Life Stress and Their Mechanism.

  2023cites this paper
• A System for Rapidly Yet Rigorously Evaluating the Quality of Randomized Controlled Trials

  2023cites this paper
• Targeted visual cortex stimulation (TVCS): a novel neuro-navigated repetitive transcranial magnetic stimulation mode for improving cognitive function in bipolar disorder

  2023cites this paper
• Lifestyle interventions for bipolar disorders: A Systematic Review and Meta-Analysis.

  2023cites this paper
• The efficacy and safety of lurasidone in bipolar I depression with and without rapid cycling: A pooled post-hoc analysis of two randomized, placebo-controlled trials.

  2023cites this paper
• Circadian Disruption and Mental Health: The Chronotherapeutic Potential of Microbiome-Based and Dietary Strategies

  2023cites this paper
• Lighting Intervention with Different Colors on Emotion: A Bayesian Network Meta-Analysis

  2023cites this paper
• Therapeutic Interventions to Mitigate Mitochondrial Dysfunction and Oxidative Stress–Induced Damage in Patients with Bipolar Disorder

  2022cites this paper
• Psychopharmacological Treatment Algorithms of Manic/Mixed and Depressed Episodes in Pediatric Bipolar Disorder

  2022cites this paper
• Effectiveness of light therapy as adjunctive treatment in bipolar depression: A pilot study.

  2022cites this paper
• Non-Medicamentous Spa Treatment of Mental Disorders

  2022cites this paper
• Lower Morning Levels Of Cortisol And Neuropeptides In Blood Samples From Patients With Bipolar Disorder

  2022cites this paper
• Luxotonic signals in human prefrontal cortex as a possible substrate for effects of light on mood and cognition

  2022cites this paper
• Prediction of Dropout in a Randomized Controlled Trial of Adjunctive Light Treatment in Patients with Non-Seasonal Depression and Evening Chronotype

  2022cites this paper
• Bipolar Disorder

  2022cites this paper
• Circadian Neuromarkers of Mood Disorders

  2022cites this paper
• Circadian rhythm and disease: Relationship, new insights, and future perspectives

  2022cites this paper
• Fact-checking Chronotherapeutic Research: Commentary on Bisdounis, et al. (2022).

  2022cites this paper
• Multi-Level Processes and Retina–Brain Pathways of Photic Regulation of Mood

  2022cites this paper
• Photobiomodulation Therapy Ameliorates Glutamatergic Dysfunction in Mice with Chronic Unpredictable Mild Stress-Induced Depression

  2021cites this paper
• PET evaluation of light-induced modulation of microglial activation and GLP-1R expression in depressive rats

  2021cites this paper
• DAILY—A Personalized Circadian Zeitgeber Therapy as an Adjunctive Treatment for Alcohol Use Disorder Patients: Study Protocol for a Randomized Controlled Trial

  2021cites this paper
• “Shedding Light on Light”: A Review on the Effects on Mental Health of Exposure to Optical Radiation

  2021cites this paper
• Preventive effect of morning light exposure on relapse into depressive episode in bipolar disorder

  2021cites this paper
• Light therapy for seasonal affective disorder in visual impairment and blindness - a pilot study.

  2021cites this paper
• Exploring potential mechanisms underpinning the therapeutic effects of surfing

  2021cites this paper
• Sleep and Memory Consolidation Dysfunction in Psychiatric Disorders: Evidence for the Involvement of Extracellular Matrix Molecules

  2021cites this paper
• Disrupted circadian rhythms and mental health.

  2021cites this paper
• Late chronotype predicts more depressive symptoms in bipolar disorder over a 5 year follow-up period

  2021cites this paper
• Outdoor daylight exposure and longer sleep promote wellbeing under COVID‐19 mandated restrictions

  2021cites this paper
• Supersensitivity of Patients With Bipolar I Disorder to Light-Induced Phase Delay by Narrow Bandwidth Blue Light

  2021cites this paper
• The influence of weather on the course of bipolar disorder: A systematic review

  2021cites this paper
• No man is an island

  2021cites this paper
• Psychological and behavioural interventions in bipolar disorder that target sleep and circadian rhythms: a systematic review of randomised controlled trials.

  2021cites this paper
• Efficacy and Safety of Light Therapy as a Home Treatment for Motor and Non-Motor Symptoms of Parkinson Disease: A Meta-Analysis

  2021cites this paper
• Luminothérapie dans les troubles de l’humeur

  2021cites this paper
• ADHD 24/7: Circadian clock genes, chronotherapy and sleep/wake cycle insufficiencies in ADHD

  2020cites this paper
• Stemmingsstoornissen

  2020cites this paper
• The Inpatient with Depression

  2020cites this paper
• Antidepressant light therapy for bipolar patients: A meta-analyses.

  2020cites this paper
• The Light of Hope in Antidepressant Strategies

  2020cites this paper
• Task-related functional magnetic resonance imaging-based neuronavigation for the treatment of depression by individualized repetitive transcranial magnetic stimulation of the visual cortex

  2020cites this paper
• Treating winter depressive episodes in bipolar disorder: an open trial of light therapy

  2020cites this paper
• Bright light therapy in the treatment of patients with bipolar disorder: A systematic review and meta-analysis

  2020cites this paper
• Response to ‘Efficacy and safety of bright light therapy for bipolar depression’

  2020cites this paper
• Light affects behavioral despair involving the clock gene Period 1

  2020cites this paper
• Efficacy and safety of bright light therapy for bipolar depression

  2020cites this paper
• Association between light exposure at night and manic symptoms in bipolar disorder: cross-sectional analysis of the APPLE cohort

  2020cites this paper
• Sleep and sleep treatments in bipolar disorder.

  2020cites this paper
• Adherence and acceptability of light therapies to improve sleep in intrinsic circadian rhythm sleep disorders and neuropsychiatric illness: a systematic review.

  2020cites this paper
• Carbon monoxide: a critical physiological regulator sensitive to light

  2020cites this paper
• Editorial: Back to the Future: On the Road Towards Precision Psychiatry

  2020cites this paper
• Role of biological rhythm dysfunction in the development and management of bipolar disorders: a review

  2020cites this paper
• Circadian rhythm disruption and mental health

  2020cites this paper
• Dynamic LED-light versus static LED-light for depressed inpatients: study protocol for a randomised clinical study

  2020cites this paper
• Efficacy and safety of bright light therapy for manic and depressive symptoms in patients with bipolar disorder: A systematic review and meta‐analysis

  2020influential citation
• Luxotonic signals in human prefrontal cortex: A possible substrate for effects of light on mood and cognition

  2020cites this paper
• Advances toward precision medicine for bipolar disorder: mechanisms & molecules

  2020cites this paper
• Efficacy of Triple Chronotherapy in unipolar and bipolar depression: A systematic review of the available evidence.

  2020cites this paper
• Sleep Medicine and Mental Health: A Guide for Psychiatrists and Other Healthcare Professionals

  2020cites this paper
• Adjunctive bright light treatment with gradual advance in unipolar major depressive disorder with evening chronotype – A randomized controlled trial

  2020cites this paper