Well-differentiated and dedifferentiated liposarcomas

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Virchows Archiv

• Publication date

  2010-02-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/s00428-009-0815-xPMID 19688222
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Pathology and Genetics

  2010cited by this paper
• Variability of origin for the neocentromeric sequences in analphoid supernumerary marker chromosomes of well-differentiated liposarcomas.

  2009cited by this paper
• HMGA2 is the partner of MDM2 in well‐differentiated and dedifferentiated liposarcomas whereas CDK4 belongs to a distinct inconsistent amplicon

  2008cited by this paper
• The prognostic impact of dedifferentiation in retroperitoneal liposarcoma

  2008cited by this paper
• Fluorescence in situ hybridization for MDM2 gene amplification as a diagnostic tool in lipomatous neoplasms

  2008cited by this paper
• Peroxisome proliferator‐activated receptor γ agonists inhibit adipocyte expression of α1‐acid glycoprotein

  2007cited by this paper
• CT‐guided, COBRA‐FISH‐assisted diagnosis of well‐differentiated liposarcoma (inflammatory subtype) of the retroperitoneum

  2007cited by this paper
• JUN oncogene amplification and overexpression block adipocytic differentiation in highly aggressive sarcomas.

  2007cited by this paper
• Gene expression profiling of liposarcoma identifies distinct biological types/subtypes and potential therapeutic targets in well-differentiated and dedifferentiated liposarcoma.

  2007cited by this paper
• Potential for treatment of liposarcomas with the MDM2 antagonist Nutlin‐3A

  2007cited by this paper
• Peroxisome proliferator-activated receptor gamma agonists inhibit adipocyte expression of alpha1-acid glycoprotein.

  2007cited by this paper
• Dedifferentiated Liposarcomas With Divergent Myosarcomatous Differentiation Developed in the Internal Trunk: A Study of 27 Cases and Comparison to Conventional Dedifferentiated Liposarcomas and Leiomyosarcomas

  2007cited by this paper
• Detection of MDM2-CDK4 Amplification by Fluorescence In Situ Hybridization in 200 Paraffin-embedded Tumor Samples: Utility in Diagnosing Adipocytic Lesions and Comparison With Immunohistochemistry and Real-time PCR

  2007influential reference
• Subtype Specific Prognostic Nomogram for Patients With Primary Liposarcoma of the Retroperitoneum, Extremity, or Trunk

  2006cited by this paper
• Cyclin-dependent kinase pathways as targets for cancer treatment.

  2006cited by this paper
• Local recurrence of myxofibrosarcoma is associated with increase in tumour grade and cytogenetic aberrations, suggesting a multistep tumour progression model

  2006cited by this paper
• Myxoid malignant fibrous histiocytoma and pleomorphic liposarcoma share very similar genomic imbalances

  2005cited by this paper
• MDM2 and CDK4 Immunostainings Are Useful Adjuncts in Diagnosing Well-Differentiated and Dedifferentiated Liposarcoma Subtypes: A Comparative Analysis of 559 Soft Tissue Neoplasms With Genetic Data

  2005influential reference
• Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors: liposarcoma.

  2004cited by this paper
• JNK activation is critical for Aplidin™-induced apoptosis

  2004cited by this paper
• Inflammatory malignant fibrous histiocytomas and dedifferentiated liposarcomas: histological review, genomic profile, and MDM2 and CDK4 status favour a single entity

  2004cited by this paper
• [From cytogenetics to cytogenomics of adipose tissue tumors: 2. Malignant adipose tissue tumors].

  2004cited by this paper
• ASK1 (MAP3K5) as a potential therapeutic target in malignant fibrous histiocytomas with 12q14–q15 and 6q23 amplifications

  2004influential reference
• De la cytogénétique à la cytogénomique des tumeurs adipocytaires 2. Tumeurs adipocytaires malignes

  2004cited by this paper
• Most Malignant Fibrous Histiocytomas Developed in the Retroperitoneum Are Dedifferentiated Liposarcomas: A Review of 25 Cases Initially Diagnosed as Malignant Fibrous Histiocytoma

  2003cited by this paper
• A subgroup of malignant fibrous histiocytomas is associated with genetic changes similar to those of well-differentiated liposarcomas.

  2002cited by this paper
• Cyclin D-dependent kinases, INK4 inhibitors and cancer.

  2002cited by this paper
• Enzinger and Weiss's Soft Tissue Tumors

  2001cited by this paper
• Dedifferentiated liposarcoma.

  2001cited by this paper
• MDM2--master regulator of the p53 tumor suppressor protein.

  2000cited by this paper
• The expression of MDM2/CDK4 gene product in the differential diagnosis of well differentiated liposarcoma and large deep-seated lipoma

  2000cited by this paper
• Characterization of centromere alterations in liposarcomas

  2000cited by this paper
• Structure of the supernumerary ring and giant rod chromosomes in adipose tissue tumors

  1999cited by this paper
• Dedifferentiated liposarcoma: a report of nine cases with a peculiar neurallike whorling pattern associated with metaplastic bone formation.

  1998cited by this paper
• Liposarcoma with meningothelial‐like whorls: a study of 17 cases of a distinctive histological pattern associated with dedifferentiated liposarcoma

  1998cited by this paper
• The cytogenetics of lipomatous tumours

  1997cited by this paper
• Well-differentiated inflammatory liposarcoma: an uncommon and easily overlooked variant of a common sarcoma.

  1997cited by this paper
• Dedifferentiated liposarcoma: a clinicopathological analysis of 155 cases with a proposal for an expanded definition of dedifferentiation.

  1997influential reference
• Heterologous Elements in the Dedifferentiated Component of Dedifferentiated Liposarcoma

  1994cited by this paper
• Dedifferentiated Liposarcoma Clinicopathologic Analysis of 32 Cases Suggesting a Better Prognostic Subgroup Among Pleomorphic Sarcomas

  1994cited by this paper
• Complex composition and co‐amplification of SAS and MDM2 in ring and giant rod marker chromosomes in well‐differentiated liposarcoma

  1994cited by this paper
• Divergent Myosarcomatous Differentiation in Retroperitoneal Liposarcoma

  1993cited by this paper
• Well-Differentiated Liposarcoma (Atypical Lipoma) of Deep Soft Tissue of the Extremities, Retroperitoneum, and Miscellaneous Sites: A Follow-up Study of 92 Cases with Analysis of the Incidence of “Dedifferentiation”

  1992cited by this paper
• Atypical and Malignant Neoplasms Showing Lipomatous Differentiation: A Study of 111 Cases

  1987cited by this paper
• Atypical lipoma, atypical intramuscular lipoma and well differentiated retroperitoneal liposarcoma

  1980cited by this paper
• Liposarcoma A study of 55 cases with a reassessment of its classification

  1979cited by this paper
• Atypical lipoma, atypical intramuscular lipoma, and well differentiated retroperitoneal liposarcoma. A reappraisal of 30 cases formerly classified as well differentiated liposarcoma

  1979cited by this paper

• Predictors of survival in dedifferentiated liposarcoma: A population-based analysis of the SEER database.

  2026cites this paper
• KNTC1 and PRC1 define an immunosuppressive microenvironment and poor prognosis in liposarcoma

  2026cites this paper
• Unusual Retroperitoneal Soft Tissue Sarcomas: Giant Masqueraders

  2025cites this paper
• The contribution of MDM2 gene ampli­fication to the differential diagnosis of liposarcomas: clinical practice in a tertiary health care facility

  2025cites this paper
• Well-Differentiated Liposarcoma in the Left Face.

  2025cites this paper
• Long-term disease control in dedifferentiated liposarcoma: a case report on trabectedin priming followed by PD-1 inhibition

  2025cites this paper
• Case Report: Diagnosis and treatment of giant thoracodorsal liposarcoma

  2025cites this paper
• Pancreatic liposarcoma: A case report

  2025cites this paper
• Curative endoscopic resection of giant esophageal dedifferentiated liposarcoma: a case report and literature review

  2025cites this paper
• Identification of the First Case of Dedifferentiated Liposarcoma in Amphibians: Insights from Maculopaa medogensis

  2024cites this paper
• Use of radiologic imaging to differentiate lipoma from atypical lipomatous tumor/well-differentiated liposarcoma: Systematic review

  2024cites this paper
• Classifying and grading liposarcoma by CT.

  2024cites this paper
• Интимальная саркома. Описание клинических случаев

  2024cites this paper
• Large atypical lipomatous tumour of the neck with mediastinal extension managed by transcervical excision

  2024cites this paper
• Cellular origin and clonal evolution of human dedifferentiated liposarcoma

  2024cites this paper
• Dedifferentiated liposarcoma of the pleura: a case report

  2024cites this paper
• Recurrent Intrathoracic Liposarcoma: A Case Report and a Comprehensive Literature Review of a Rare Clinical Entity

  2024influential citation
• Dedifferentiated Liposarcoma: A Rare Entity

  2024cites this paper
• Relapse of Atypical Spindle Cell/Pleomorphic Lipomatous Tumor With New Amplification in the 12q13-15 Region.

  2024cites this paper
• Precision Medicine in Cytopathology.

  2024cites this paper
• An overview on liposarcoma subtypes: Genetic alterations and recent advances in therapeutic strategies

  2024cites this paper
• Diagnosing liposarcoma on (peri)‐renal mass biopsy: A clinicopathological study of 30 cases

  2024cites this paper
• The association between CD34 expression status and the clinicopathological behavior of dedifferentiated liposarcoma.

  2024cites this paper
• Primary dedifferentiated liposarcoma of the gallbladder: a case report and literature review.

  2024cites this paper
• Whole exome sequencing of well-differentiated liposarcoma and dedifferentiated liposarcoma in older woman: a case report

  2023cites this paper
• Prognostic value of clinical and MRI features in the screening of lipomatous lesions.

  2023cites this paper
• Sarcoma care in the era of precision medicine

  2023cites this paper
• Immunohistochemical Expression of p16 and CDK4 in Soft Tissue Tumors

  2023cites this paper
• MDM2 for the practicing pathologist: a primer

  2023cites this paper
• A metabolic crosstalk between liposarcoma and muscle sustains tumor growth

  2023cites this paper
• Low local recurrence rates following marginal surgical resection of non-coelomic Atypical Lipomatous Tumours/Well-differentiated Liposarcomas.

  2023cites this paper
• Does “Low-Grade” Dedifferentiated Liposarcoma Exist? The Role of Mitotic Index in Separating Dedifferentiated Liposarcoma From Cellular Well-differentiated Liposarcoma

  2023cites this paper
• MDM2 amplification is rare in gastric cancer

  2023cites this paper
• Case Report: Primary low-grade dedifferentiated liposarcoma of the urinary bladder with molecular confirmation

  2023cites this paper
• Unravelling homologous recombination repair deficiency and therapeutic opportunities in soft tissue and bone sarcoma

  2023cites this paper
• Silver In Situ Hybridization for the Rapid Assessment of MDM2 Amplification in Soft Tissue and Bone Tumors. Validation Based on an Audit of 192 Consecutive Cases Evaluated by Silver In Situ Hybridization and Fluorescence In Situ Hybridization

  2023cites this paper
• Dedifferentiated liposarcoma primary to the chest wall with spontaneous shrinking: report of a case

  2023cites this paper
• Established and Experimental Systemic Treatment Options for Advanced Liposarcoma

  2022cites this paper
• Recurrent primary orbital well-differentiated liposarcoma /atypical lipomatous tumor: A rare case report with six-year follow-up

  2022cites this paper
• Liposarcoma subtype recurrence and survival: A UK regional cohort study.

  2022cites this paper
• Molecular classification of soft tissue sarcomas for adequate diagnosis: A study on the northeast population of Morocco

  2022cites this paper
• Clinical decision-making strategies for rare somatic variants in cancer

  2022cites this paper
• CD44 In Sarcomas: A Comprehensive Review and Future Perspectives

  2022cites this paper
• The Genomics of Liposarcoma: A Review and Commentary

  2022cites this paper
• Detection of MDM2 amplification by shallow whole genome sequencing of cell-free DNA of patients with dedifferentiated liposarcoma

  2022cites this paper
• Head pleomorphic sarcoma showing murine double minute 2 amplification without a well‐differentiated liposarcoma component in a pediatric patient

  2022influential citation
• Dedifferentiated liposarcoma in the extremity and trunk wall: A multi-institutional study of 132 cases by the Japanese Musculoskeletal Oncology Group (JMOG).

  2022cites this paper
• Radiomics of Musculoskeletal Sarcomas: A Narrative Review

  2022cites this paper
• The Immune Contexture of Liposarcoma and Its Clinical Implications

  2022influential citation
• Evaluation Criteria for Chromosome Instability Detection by FISH to Predict Malignant Progression in Premalignant Glottic Laryngeal Lesions

  2022cites this paper
• The Molecular Biology of Soft Tissue Sarcomas: Current Knowledge and Future Perspectives

  2022influential citation
• What’s new in adipocytic neoplasia?

  2021cites this paper
• Resection Status Does Not Impact Recurrence in Well-Differentiated Liposarcoma of the Extremity

  2021cites this paper
• Differential diagnosis of lipoma and atypical lipomatous tumor/well‐differentiated liposarcoma by cytological analysis

  2021cites this paper
• Retroperitoneal Liposarcoma: A Case Report and Review of Literature

  2021cites this paper
• The utility of fluorescence in situ hybridization (FISH) in determining DNA damage-inducible transcript 3 (DDIT3) amplification in dedifferentiated liposarcomas - an important diagnostic pitfall.

  2021cites this paper
• Inhibition of P53-mediated cell cycle control as the determinant in dedifferentiated liposarcomas development.

  2021cites this paper
• Retroperitoneal Dedifferentiated Liposarcoma.

  2021cites this paper
• Decoded: A Case Report on Dedifferentiated Liposarcoma on the Gluteal Area

  2021cites this paper
• Impact of Pathological Stratification on the Clinical Outcomes of Advanced Well-Differentiated/Dedifferentiated Liposarcoma Treated with Trabectedin

  2021cites this paper
• A scoring system combining clinical, radiological, and histopathological examinations for differential diagnosis between lipoma and atypical lipomatous tumor/well-differentiated liposarcoma

  2021cites this paper
• Risk Factors of Survival in Dedifferentiated Liposarcoma

  2021cites this paper
• Giant Perinephric Dedifferentiated Liposarcoma Masquerading Cystic Renal Tumor: A Case Report and Literature Review

  2021cites this paper
• [Retroperitoneal dedifferentiated liposarcomas: semi-quantitative assessment of the dedifferentiated component and prognosis].

  2020cites this paper
• A Retrospective Study of Superficial Type Atypical Lipomatous Tumor

  2020cites this paper
• Parosteal osteosarcoma associated with a low-grade component mimicking well-differentiated liposarcoma: a case report

  2020cites this paper
• Scrotal liposarcoma: Case report of a rare extratesticular mass

  2020cites this paper
• Pilot study to differentiate lipoma from atypical lipomatous tumour/well-differentiated liposarcoma using MR radiomics-based texture analysis

  2020cites this paper
• Thoracoscopic resection of a huge esophageal dedifferentiated liposarcoma: A case report.

  2020cites this paper
• Diagnosis of Musculoskeletal Tumors and Tumor-like Conditions: Clinical, Radiological and Histological Correlations - The Rizzoli Case Archive

  2020cites this paper
• Expanding the differential of cutaneous epithelioid tumors: A case of dedifferentiated liposarcoma with epithelioid features involving the skin, with review of the literature

  2020cites this paper
• C World Journal of Clinical Cases Thoracoscopic resection of a huge esophageal dedifferentiated liposarcoma: A case report

  2020cites this paper
• Soft Tissue Tumour Pathology

  2020cites this paper
• Differentiating atypical lipomatous tumors from lipomas with magnetic resonance imaging: a comparison with MDM2 gene amplification status

  2019cites this paper
• Treatment Facility: An Important Prognostic Factor for Dedifferentiated Liposarcoma Survival

  2019cites this paper
• A Case of Retroperitoneal Liposarcoma Mimicking an Adrenocortical Carcinoma

  2019cites this paper
• Adipogenesis induces growth inhibition of dedifferentiated liposarcoma

  2019cites this paper
• What’s new in adipocytic neoplasia?

  2019cites this paper
• Surprising Bone and Soft Tissue Lesions of the Chest: Pictorial Review

  2019cites this paper
• MDM2 Inhibition in a Subset of Sarcoma Cell Lines Increases Susceptibility to Radiation Therapy by Inducing Senescence in the Polyploid Cells

  2019cites this paper
• Phase 1 study of the MDM2 inhibitor AMG 232 in patients with advanced P53 wild-type solid tumors or multiple myeloma

  2019cites this paper
• [Mass of adipose tissue: Inflammation, pseudo-tumour and tumour: The cornelian fan: Case No. 4].

  2019cites this paper
• A Low-Grade Myxoid Liposarcoma Arising in a Deep-Seated Conventional Lipoma

  2019cites this paper
• RETROPERITONEAL NON-ORGAN LIPOSARCOMAS: THE MODERN CONCEPT

  2019influential citation
• Liposarcomas

  2019cites this paper
• Increased H 3 K 9 me 3 drives dedifferentiated phenotype via KLF 6 repression in liposarcoma

  2019cites this paper
• The PTEN Tumor Suppressor Gene in Soft Tissue Sarcoma

  2019cites this paper
• Low-grade Osteosarcomatous Dedifferentiation of an Atypical Lipomatous Tumor in a Pediatric Patient

  2019cites this paper
• Molecular Characterization of a Rare Dedifferentiated Liposarcoma With Rhabdomyosarcomatous Differentiation in a 24 Year Old

  2019cites this paper
• Treatment Facility: An Important Prognostic Factor for Dedifferentiated Liposarcoma Survival.

  2019cites this paper
• Thoracic Liposarcoma In An End Stage Renal Disease Patient.

  2019cites this paper
• Dedifferentiated Liposarcoma of the Left Thigh: a Rare Case

  2019influential citation
• A contemporary review of myxoid adipocytic tumors.

  2019cites this paper
• Pharmacotherapy for liposarcoma: current state of the art and emerging systemic treatments

  2019influential citation
• Allosteric changes in HDM2 by the ATM phosphomimetic S395D mutation: implications on HDM2 function

  2019cites this paper
• MDM2 RNA In Situ Hybridization for the Diagnosis of Atypical Lipomatous Tumor: A Study Evaluating DNA, RNA, and Protein Expression

  2019cites this paper
• ЗАБРЮШИННЫЕ НЕОРГАННЫЕ ЛИПОСАРКОМЫ: СОВРЕМЕННЫЙ ВЗГЛЯД НА ПРОБЛЕМУ

  2019cites this paper
• Pleomorphic Liposarcoma of Finger–a Rare Entity

  2019cites this paper
• Well-differentiated liposarcoma and dedifferentiated liposarcoma: An updated review.

  2019cites this paper
• Markers and Immunoprofile of Adipocytic Tumors

  2018cites this paper