Evidence for autoimmunity to myosin and other heart-specific autoantigens in patients with dilated cardiomyopathy and their relatives.

No abstract is available for this paper.

• Publication year

  1996

• Venue

  International Journal of Cardiology

• Publication date

  1996-05-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/0167-5273(96)02593-4PMID 8803680
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Soluble interleukin-2 receptor levels in patients with dilated cardiomyopathy. Correlation with disease severity and cardiac autoantibodies.

  1995cited by this paper
• Familial dilated cardiomyopathy in the United Kingdom.

  1995cited by this paper
• Autoimmunity to alpha myosin in a subset of patients with idiopathic dilated cardiomyopathy.

  1995cited by this paper
• Organ-specific cardiac autoantibodies in dilated cardiomyopathy. Frequency and clinical correlates in Polish patients.

  1995cited by this paper
• Organ-specific autoimmunity.

  1995cited by this paper
• Circulating heart autoantibodies in familial as compared with nonfamilial idiopathic dilated cardiomyopathy.

  1994cited by this paper
• Role of autoimmunity in dilated cardiomyopathy.

  1994cited by this paper
• Low frequency of detection by nested polymerase chain reaction of enterovirus ribonucleic acid in endomyocardial tissue of patients with idiopathic dilated cardiomyopathy.

  1994cited by this paper
• A prospective case-control study of antibodies to coxsackie B virus in idiopathic dilated cardiomyopathy.

  1994cited by this paper
• Autoantibodies against human ventricular myosin in sera of patients with acute and chronic myocarditis.

  1994cited by this paper
• Molecular biology of IDDM

  1994cited by this paper
• Clinical and prognostic significance of detection of enteroviral RNA in the myocardium of patients with myocarditis or dilated cardiomyopathy.

  1994cited by this paper
• Evidence from family studies for autoimmunity in dilated cardiomyopathy.

  1994cited by this paper
• Induction of multiple heart autoantibodies in mice with coxsackievirus B3- and cardiac myosin-induced autoimmune myocarditis.

  1994cited by this paper
• Defining criteria for autoimmune diseases (Witebsky's postulates revisited)

  1993cited by this paper
• Failure to demonstrate enterovirus aetiology in Swedish patients with dilated cardiomyopathy

  1993cited by this paper
• Frequency and specificity of antiheart antibodies in patients with dilated cardiomyopathy detected using SDS-PAGE and western blotting.

  1993cited by this paper
• Familial aggregation of idiopathic dilated cardiomyopathy: clinical features and pedigree analysis in 14 families.

  1993cited by this paper
• Localization of a functional autoimmune epitope on the muscarinic acetylcholine receptor-2 in patients with idiopathic dilated cardiomyopathy.

  1993cited by this paper
• Idiopathic dilated cardiomyopathy: lack of association between circulating organ-specific cardiac antibodies and HLA-DR antigens.

  1992cited by this paper
• Identification of alpha- and beta-cardiac myosin heavy chain isoforms as major autoantigens in dilated cardiomyopathy.

  1992cited by this paper
• Similar prevalence of enteroviral genome within the myocardium from patients with idiopathic dilated cardiomyopathy and controls by the polymerase chain reaction

  1992cited by this paper
• HLA and immunoglobulin polymorphisms in idiopathic dilated cardiomyopathy.

  1992cited by this paper
• Expression of myosin-class II major histocompatibility complexes in the normal myocardium occurs before induction of autoimmune myocarditis.

  1992cited by this paper
• The frequency of familial dilated cardiomyopathy in a series of patients with idiopathic dilated cardiomyopathy.

  1992cited by this paper
• Autoantibodies against the beta-adrenergic receptor in human myocarditis and dilated cardiomyopathy: beta-adrenergic agonism without desensitization.

  1991cited by this paper
• Beta-adrenoceptor antibodies and genetics in dilated cardiomyopathy--an overview and review.

  1991cited by this paper
• HLA class II (DR and DQ) antigen associations in idiopathic dilated cardiomyopathy. Validation study and meta-analysis of published HLA association studies.

  1991cited by this paper
• Myosin-induced acute myocarditis is a T cell-mediated disease.

  1991cited by this paper
• Antigen presentation: structural themes and functional variations.

  1991cited by this paper
• Autoantibodies against the β-adrenergic receptor in human myocarditis and dilated cardiomyopathy: β-adrenergic agonism without desensitization

  1991cited by this paper
• Clinical and pathologic study of familial dilated cardiomyopathy.

  1990cited by this paper
• Mapping of a functional autoimmune epitope on the beta 1-adrenergic receptor in patients with idiopathic dilated cardiomyopathy.

  1990cited by this paper
• Novel organ-specific circulating cardiac autoantibodies in dilated cardiomyopathy.

  1990cited by this paper
• Circulating heart-reactive antibodies in patients with myocarditis or cardiomyopathy.

  1990cited by this paper
• Inappropriate major histocompatibility complex expression on cardiac tissue in dilated cardiomyopathy. Relevance for autoimmunity?

  1990cited by this paper
• The Registry of the International Society for Heart Transplantation: seventh official report--1990.

  1990cited by this paper
• Advances in Cardiomyopathies

  1990cited by this paper
• Biomolecular Changes in Dilated Cardiomyopathy

  1990cited by this paper
• Antibody-mediated enhancement of calcium permeability in cardiac myocytes

  1988cited by this paper
• Myocarditis. A histopathologic definition and classification.

  1987cited by this paper
• Coxsackievirus B-3 myocarditis. Acute and chronic forms of the disease caused by different immunopathogenic mechanisms.

  1987cited by this paper
• Cardiac myosin induces myocarditis in genetically predisposed mice.

  1987cited by this paper
• Organ‐Specific Autoimmunity: A 1986 Overview

  1986cited by this paper
• Demonstration of organ specific antibodies against heart mitochondria (anti-M7) in sera from patients with some forms of heart diseases.

  1984cited by this paper
• Clinical and pathologic findings of myocarditis in two families with dilated cardiomyopathy.

  1984cited by this paper
• Diagnostic relevance of humoral and cytotoxic immune reactions in primary and secondary dilated cardiomyopathy.

  1983cited by this paper
• Reduced Suppressor Cell Activity in Congestive Cardiomyopathy and in Myocarditis

  1982cited by this paper
• Deficient natural killer cell activity in patients with idiopathic dilated cardiomyopathy.

  1982cited by this paper
• Diagnostic relevance of humoral and cell-mediated immune reactions in patients with acute viral myocarditis.

  1982cited by this paper
• The natural history of idiopathic dilated cardiomyopathy.

  1981cited by this paper
• Viral myocarditis. A review.

  1980cited by this paper
• Viral myocarditis. A review.

  1980cited by this paper

• Cardiac autoantibodies promote a fibrotic transcriptome and reduced ventricular recovery in human myocarditis

  2025cites this paper
• IgE and cardiac disease

  2025cites this paper
• Autoimmune-Like Mechanism in Heart Failure Enables Preventive Vaccine Therapy

  2024cites this paper
• Comparison of COVID-19 Vaccine-Associated Myocarditis and Viral Myocarditis Pathology

  2023cites this paper
• Cardio-Immunology of Myocarditis: Focus on Immune Mechanisms and Treatment Options

  2019cites this paper
• Galectin-3 deficiency enhances type 2 immune cell-mediated myocarditis in mice

  2018cites this paper
• Lipoxin A4 mitigates experimental autoimmune myocarditis by regulating inflammatory response, NF-κB and PI3K/Akt signaling pathway in mice.

  2017cites this paper
• Chapter 1 - Cellular Immunity: A Role for Cytokines

  2017cites this paper
• Complete Freund's adjuvant induces experimental autoimmune myocarditis by enhancing IL‐6 production during initiation of the immune response

  2017cites this paper
• Gene expression analysis during recovery process indicates the mechanism for innate immune injury and repair from Coxsackievirus B3-induced myocarditis.

  2016cites this paper
• Phosphoinositide 3-kinase inhibitor LY294002 ameliorates the severity of myosin-induced myocarditis in mice.

  2016cites this paper
• ASPECTE MOLECULARE ŞI IMUNOLOGICE ALE CARDIOMIOPATIEI DILATATIVE ÎN PEDIATRIE

  2016cites this paper
• Prompt benefit of early immunosuppressive therapy in acute lymphocytic myocarditis with persistent heart failure

  2016cites this paper
• Auto-antibodies as possible markers and mediators of ischemic, dilated, and rhythmic cardiopathies.

  2015cites this paper
• Signaling in Autoimmune Myocarditis Mimicry and Antibody-Mediated Cell

  2015cites this paper
• Oleanolic acid modulates the immune-inflammatory response in mice with experimental autoimmune myocarditis and protects from cardiac injury. Therapeutic implications for the human disease.

  2014cites this paper
• Protective Role of the Cholinergic Anti-Inflammatory Pathway in a Mouse Model of Viral Myocarditis

  2014cites this paper
• Cross-sectional study: CagA–positive Helicobacter pylori infection, acute coronary artery disease and systemic levels of B-type natriuretic peptide

  2013cites this paper
• Advances in monoclonal antibody application in myocarditis

  2013cites this paper
• Acute viral myocarditis: current concepts in diagnosis and treatment.

  2013cites this paper
• Myocardial performance in children with autoimmune hepatitis: Doppler tissue imaging study

  2013cites this paper
• Autoimmune Myocarditis, Valvulitis, and Cardiomyopathy

  2013influential citation
• acute v iral myocarditis: c urrent c oncepts in diagnosis and t reatment

  2013cites this paper
• Current treatment options in (peri)myocarditis and inflammatory cardiomyopathy

  2012cites this paper
• Recent clinical and translational research on pediatric myocarditis.

  2011cites this paper
• Effects of protein A immunoadsorption on methylglyoxal levels in patients with chronic dilated cardiomyopathy and diabetes mellitus

  2011cites this paper
• Effects of protein A immunoadsorption in patients with chronic dilated cardiomyopathy

  2010cites this paper
• Contribution of TLR7 and TLR9 signaling to the susceptibility of MyD88-deficient mice to myocarditis

  2010cites this paper
• Role of Toll-like receptor 8 in the development of spontaneous autoimmunity in mice

  2010influential citation
• Cutting Edge: Cardiac Myosin Activates Innate Immune Responses through TLRs1

  2009cites this paper
• Spontaneous autoimmune myocarditis and cardiomyopathy in HLA-DQ8.NODAbo transgenic mice.

  2009cites this paper
• Turning point in myocarditis.

  2009cites this paper
• Throat infection, neck and chest pain and cardiac response: A persistent infection-related clinical syndrome

  2009cites this paper
• Effects of protein A immunoadsorption in patients with advanced chronic dilated cardiomyopathy

  2009cites this paper
• Innate Immune Responses through TLRs Cutting Edge: Cardiac Myosin Activates

  2009cites this paper
• Consequences of unlocking the cardiac myosin molecule in human myocarditis and cardiomyopathies

  2008cites this paper
• Autoantibodies in atrial fibrillation: Actor, biomaker or bystander?

  2008cites this paper
• Expressão de citocinas inflamatórias e quimiocinas no tecido cardíaco de pacientes com Cardiomiopatia Chagásica Crônica

  2008cites this paper
• HLA-DRB1 gene polymorphism in patients with dilated cardiomyopathy

  2008cites this paper
• Possible association of HLA-DRB1 gene with the autoantibody against myocardial mitochondria ADP/ATP carrier in dilated cardiomyopathy

  2008cites this paper
• Circulating autoantibodies to troponin I in Emery-Dreifuss muscular dystrophy.

  2008cites this paper
• Autoantibodies in Atrial Fibrillation: Actors, Biomarkers or Bystanders? How Far Have We Come?

  2008cites this paper
• Discovering novel targets for autoantibodies in dilated cardiomyopathy

  2008cites this paper
• Morphologische und molekularpathologische Befunde bei Parvovirus B19- und Humanem Herpesvirus vomTyp 6-assoziierter Myokarditis.Eine Follow-up-Studie

  2008cites this paper
• Integrated Biomarkers in Cardiomyopathies

  2007cites this paper
• Genetics of autoreactive B cells.

  2007cites this paper
• Spontaneous myocarditis mimicking human disease occurs in the presence of an appropriate MHC and non-MHC background in transgenic mice.

  2007cites this paper
• Integrated biomarkers in cardiomyopathies: cardiovascular magnetic resonance imaging combined with molecular and immunologic markers--a stepwise approach for diagnosis and treatment.

  2007cites this paper
• Autoimmunological features in inflammatory cardiomyopathy

  2007cites this paper
• Immunopathogenesis of Dilated Cardiomyopathy. Evidence for the Role of TH2-Type CD4+T Lymphocytes and Association with Myocardial HLA-DR Expression

  2006cites this paper
• Mimicry and Antibody-Mediated Cell Signaling in Autoimmune Myocarditis1

  2006cites this paper
• National Institutes of Health-sponsored workshop on inflammation and immunity in dilated cardiomyopathy.

  2006cites this paper
• Genetics of Autoimmune Myocarditis

  2006cites this paper
• T regulatory cells: sentinels against autoimmune heart disease.

  2006cites this paper
• Chronic heart failure: a report from the Dartmouth Diastole Discourses.

  2006cites this paper
• Two Autoimmune Diabetes Loci Influencing T Cell Apoptosis Control Susceptibility to Experimental Autoimmune Myocarditis1

  2005cites this paper
• Protection against experimental autoimmune myocarditis is mediated by interleukin-10-producing T cells that are controlled by dendritic cells.

  2005cites this paper
• Inflammatory Dilated Cardiomyopathy (DCMI)

  2005cites this paper
• Immunogenicity of a DNA vaccine for coxsackievirus B3 in mice: protective effects of capsid proteins against viral challenge.

  2005cites this paper
• Pre- and post-transplant anti-myosin and anti-heat shock protein antibodies and cardiac transplant outcome.

  2004cites this paper
• Endothelial expression of MHC class II molecules in autoimmune disease.

  2004cites this paper
• T cell mimicry in inflammatory heart disease.

  2004cites this paper
• Implication du récepteur 5-HT4 cardiaque humain dans la fibrillation auriculaire : rôle d’auto-anticorps dirigés contre ce récepteur ?

  2004cites this paper
• Angiotensin converting enzyme inhibitors and angiotensin II receptor antagonists in experimental myocarditis.

  2003cites this paper
• IL-12 is required for differentiation of pathogenic CD8+ T cell effectors that cause myocarditis.

  2003cites this paper
• Interleukin-6–Deficient Mice Resist Development of Autoimmune Myocarditis Associated With Impaired Upregulation of Complement C3

  2003cites this paper
• Autoimmune cardiomyopathy and heart block develop spontaneously in HLA-DQ8 transgenic IAβ knockout NOD mice

  2003cites this paper
• Human viral cardiomyopathy.

  2003cites this paper
• Myocarditis and dilated cardiomyopathy: an inflammatory link.

  2003cites this paper
• Humoral Immune Response in Viral Myocarditis

  2003cites this paper
• Cellular Immunity: A Role for Cytokines

  2003cites this paper
• Dilated Cardiomyopathies and Congestive Heart Failure

  2003cites this paper
• Dilatative Kardiomyopathie und Myokarditis Aktuelle diagnostische Erfordernisse und therapeutische Möglichkeiten

  2002cites this paper
• Dilated Cardiomyopathies as a Cause of Congestive Heart Failure

  2002cites this paper
• Pathophysiology of viral myocarditis: the role of humoral immune response.

  2002cites this paper
• Cytokines that regulate autoimmune myocarditis.

  2002cites this paper
• Cardiomyopathy is linked to complement activation.

  2002cites this paper
• Nicht-invasive darstellung komplexer perianaller fistelgangsysteme mittels hochauflösender MRT in 3D-sequenztechnik

  2002cites this paper
• Immune mediators in inflammatory heart disease: insights from a mouse model

  2002cites this paper
• Myocarditis

  2002cites this paper
• [Dilated cardiomyopathy and myocarditis. Current diagnostic requirements and therapeutic possibilities].

  2002cites this paper
• Experimental autoimmune myocarditis in A/J mice is an interleukin-4-dependent disease with a Th2 phenotype.

  2001cites this paper
• Managing heart failure with immunomodulatory agents.

  2001cites this paper
• Cardiac myosin and the TH1/TH2 paradigm in autoimmune myocarditis.

  2001cites this paper
• Antibodies to an Epitope from the Cha Human Autoantigen Are Markers of Chagas' Disease

  2001cites this paper
• Dual role of the IL-12/IFN-gamma axis in the development of autoimmune myocarditis: induction by IL-12 and protection by IFN-gamma.

  2001cites this paper
• Characterization of anti-myocardial autoantibodies in Japanese patients with dilated cardiomyopathy.

  2001cites this paper
• Dual Role of the IL-12/IFN-γ Axis in the Development of Autoimmune Myocarditis: Induction by IL-12 and Protection by IFN-γ1

  2001cites this paper
• Induction of Cardiomyopathy in Severe Combined Immunodeficiency Mice by Transfer of Lymphocytes from Patients with Idiopathic Dilated Cardiomyopathy

  2000cites this paper
• Identification and characterization of the antigen presenting cell in rat autoimmune myocarditis: evidence of bone marrow derivation and non-requirement for MHC class I compatibility with pathogenic T cells.

  2000cites this paper
• Definition of Inflammatory Cardiomyopathy (Myocarditis): On the Way to Consensus A Status Report

  2000cites this paper
• Chronic myocarditis induced by T cells reactive to a single cardiac myosin peptide: persistent inflammation, cardiac dilatation, myocardial scarring and continuous myocyte apoptosis.

  2000cites this paper
• Viral damage or ‘molecular mimicry’—placing the blame in myocarditis

  2000cites this paper
• Necropsy diagnosis of myocarditis: a retrospective study using CD45RO immunohistochemistry

  2000cites this paper
• Induction of cardiomyopathy in severe combined immunodeficiency mice by transfer of lymphocytes from patients with idiopathic dilated cardiomyopathy.

  2000cites this paper
• Alterations in cardiac function and gene expression during autoimmune myocarditis in mice.

  2000cites this paper
• Enzyme-linked immunosorbent assay for anti-tropomyosin antibodies and its clinical application to various heart diseases.

  2000cites this paper
• Antigenic Mimicry between Self and Coxsackievirus Proteins Leads to Both Humoral and Cellular Autoimmunity to Heart Proteins

  2000cites this paper
• Myocarditis

  2000cites this paper
• IgG subclass reactivity to human cardiac myosin in cardiomyopathy patients is indicative of a Th1‐like autoimmune disease

  1999cites this paper