Three novel fusion transcripts of the paired box 5 gene in B-cell precursor acute lymphoblastic leukemia

G. Fazio,G. Daniele,V. Cazzaniga,L. Impera,M. Severgnini,I. Iacobucci,M. Galbiati,A. Leszl,I. Cifola,G. De Bellis,P. Bresciani,G. Martinelli,G. Basso,A. Biondi,C. Storlazzi,G. Cazzaniga

Published 2015 in Haematologica

ABSTRACT

PAX5 encodes for a transcription factor essential for B-lymphoid cell commitment and is rearranged in 30% of B-cell precursor acute lymphoblastic leukemia pediatric patients (BCP-ALL).[1][1] Since the first characterization of PAX5/ETV6 ,[2][2] an increasing number of PAX5 fusion genes have been

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