Amino acid sequence of the alpha subunit of transducin deduced from the cDNA sequence.

No abstract is available for this paper.

• Publication year

  1985

• Venue

  Proceedings of the National Academy of Sciences of the United States of America

• Publication date

  1985-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1073/PNAS.82.13.4311PMID 2409555PMCID PMC390403
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• ADP-ribosylation of transducin by islet-activation protein. Identification of asparagine as the site of ADP-ribosylation.

  1984cited by this paper
• Purification and properties of the inhibitory guanine nucleotide regulatory unit of brain adenylate cyclase.

  1984cited by this paper
• Genes in S. cerevisiae encoding proteins with domains homologous to the mammalian ras proteins.

  1984cited by this paper
• Amino acid sequence of retinal transducin at the site ADP-ribosylated by cholera toxin.

  1984cited by this paper
• ADP-ribosylation of transducin by pertussis toxin blocks the light-stimulated hydrolysis of GTP and cGMP in retinal photoreceptors.

  1984cited by this paper
• Isolation of two proteins with high affinity for guanine nucleotides from membranes of bovine brain.

  1984cited by this paper
• Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs.

  1984cited by this paper
• Characterization of transducin from bovine retinal rod outer segments. The role of sulfhydryl groups.

  1984cited by this paper
• Homologies between signal transducing G proteins and ras gene products.

  1984cited by this paper
• Harvey murine sarcoma virus p21 ras protein: biological and biochemical significance of the cysteine nearest the carboxy terminus.

  1984cited by this paper
• G proteins and dual control of adenylate cyclase.

  1984cited by this paper
• The Drosophila ras oncogenes: structure and nucleotide sequence.

  1984cited by this paper
• Comparative biochemical properties of normal and activated human ras p21 protein

  1984cited by this paper
• Biological properties of human c-Ha-ras1 genes mutated at codon 12

  1984cited by this paper
• Complete nucleotide sequences of the T24 human bladder carcinoma oncogene and its normal homologue

  1983cited by this paper
• Characterization of transducin from bovine retinal rod outer segments. II. Evidence for distinct binding sites and conformational changes revealed by limited proteolysis with trypsin.

  1983cited by this paper
• ras-Related gene sequences identified and isolated from Saccharomyces cerevisiae

  1983cited by this paper
• The regulatory components of adenylate cyclase and transducin. A family of structurally homologous guanine nucleotide-binding proteins.

  1983cited by this paper
• Regional homology in GTP-binding proto-oncogene products and elongation factors

  1983cited by this paper
• Yeast RNA polymerase II genes: isolation with antibody probes.

  1983cited by this paper
• Identification of the predominant substrate for ADP-ribosylation by islet activating protein.

  1983cited by this paper
• Regional homology in GTP-binding proto-oncogene products and elongation factors.

  1983cited by this paper
• Transducin and the cyclic GMP phosphodiesterase: amplifier proteins in vision.

  1983cited by this paper
• Characterization of transducin from bovine retinal rod outer segments. I. Separation and reconstitution of the subunits.

  1983cited by this paper
• Isolation, sequence analysis, and intron-exon arrangement of the gene encoding bovine rhodopsin.

  1983cited by this paper
• Functional homology between signal-coupling proteins. Cholera toxin inactivates the GTPase activity of transducin.

  1982cited by this paper
• The primary structure of elongation factor G from Escherichia coli. A complete amino acid sequence.

  1982cited by this paper
• Flow of information in the light-triggered cyclic nucleotide cascade of vision.

  1981cited by this paper
• A system for shotgun DNA sequencing.

  1981cited by this paper
• Conformational changes of adenylate cyclase regulatory proteins mediated by guanine nucleotides.

  1981cited by this paper
• The amino acid sequence of elongation factor Tu of Escherichia coli. The complete sequence.

  1981cited by this paper
• Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

  1980cited by this paper
• Guanine nucleotide-binding and autophosphorylating activities associated with the p21src protein of Harvey murine sarcoma virus

  1980cited by this paper
• Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease.

  1979cited by this paper
• The GTP‐binding center of elongation factor G is located in its N‐terminal domain

  1978cited by this paper
• The role of guanosine 5'-triphosphate in polypeptide chain elongation.

  1978cited by this paper
• The primary structure of elongation factor G from Escherichia coli Amino acid sequence of the region containing the GTP‐binding center

  1978cited by this paper
• DNA sequencing with chain-terminating inhibitors.

  1977cited by this paper
• Mechanism of adenylate cyclase activation by cholera toxin: inhibition of GTP hydrolysis at the regulatory site.

  1977cited by this paper
• A general method for isolation of high molecular weight DNA from eukaryotes.

  1976cited by this paper
• Detection of specific sequences among DNA fragments separated by gel electrophoresis.

  1975cited by this paper
• Purification of biologically active globin messenger RNA by chromatography on oligothymidylic acid-cellulose.

  1972cited by this paper

• The Role of Galphaz in Neuron Development and CNS Biology

  2011cites this paper
• Gustducin and transducin: a tale of two G proteins.

  2007cites this paper
• Expansion of signal transduction by G proteins. The second 15 years or so: from 3 to 16 alpha subunits plus betagamma dimers.

  2007cites this paper
• Expansion of signal transduction by G proteins The second 15 years or so: From 3 to 16 α subunits plus βγ dimers

  2007cites this paper
• Why photoreceptors die (and why they don't)

  2006cites this paper
• G-proteins and GPCrs: from the beginning.

  2006cites this paper
• PDE6 is an effector for the Wnt/Ca2+/cGMP-signalling pathway in development.

  2004cites this paper
• Wnt-frizzled signaling to G-protein-coupled effectors

  2003cites this paper
• Semaphorin 3F gene from human 3p21.3 suppresses tumor formation in nude mice.

  2002cites this paper
• Semaphorin 3 F Gene from Human 3 p 21 . 3 Suppresses Tumor Formation in Nude Mice 1

  2002cites this paper
• Molecular evolution of proteins involved in vertebrate phototransduction.

  2002cites this paper
• Regulation of Xenopus oocyte meiosis arrest by G protein betagamma subunits.

  2001cites this paper
• Regulation of Xenopus oocyte meiosis arrest by G protein βγ subunits

  2001cites this paper
• Expression of Exogenous Proteins in Porcine Maturing Oocytes after mRNA Injection: Kinetic Analysis and Oocyte Selection Using EGFP mRNA

  2001cites this paper
• GTP-binding proteins in plants

  1999cites this paper
• Cloning and analysis of the cDNA encoding the rod G-protein transduction alpha, beta1 and gamma1 subunits from the canine retina.

  1997cites this paper
• G Protein‐Coupled Receptors and the G Protein Family

  1997cites this paper
• Chaperonin-mediated folding in the eukaryotic cytosol proceeds through rounds of release of native and nonnative forms.

  1997cites this paper
• Cloning and analysis of the cDNA encoding the rod G-protein transducin α, β1 and γ1 subunits from the canine retina

  1997cites this paper
• Increase of protein tyrosine phosphorylation in rat retina after ischemia-reperfusion injury.

  1996cites this paper
• Coupling of bitter receptor to phosphodiesterase through transducin in taste receptor cells

  1995cites this paper
• Molecular cloning and characterization of RGA1 encoding a G protein α subunit from rice (Oryza sativa L. IR-36)

  1995cites this paper
• GTP-binding proteins 1: heterotrimeric G proteins.

  1995cites this paper
• The Effect of Carboxyl-terminal Mutagenesis of G on Rhodopsin and Guanine Nucleotide Binding (*)

  1995cites this paper
• Isoprenylated protein endopeptidase.

  1994cites this paper
• Improved large-scale purification of transducin, and its alpha and beta gamma subunits from frozen retinas.

  1994cites this paper
• Enzymatic and nonenzymatic ADP-ribosylation of cysteine

  1994cites this paper
• Identification of a binding site on retinal transducin alpha for the phosphodiesterase inhibitory gamma subunit.

  1994cites this paper
• Effects of the amphiphilic peptides mastoparan and adenoregulin on receptor binding, G proteins, phosphoinositide breakdown, cyclic AMP generation, and calcium influx

  1994cites this paper
• [44] Isoprenylated protein endopeptidase

  1994cites this paper
• GTP-binding proteins. 1: heterotrimeric G proteins.

  1994cites this paper
• Molecular cloning of G proteins and phosphodiesterases from rat taste cells.

  1994cites this paper
• Gustducin and Transducin Are Present in Taste Cells

  1994cites this paper
• Repair and replacement to restore sight. Report from the Panel on Photoreceptor/Retinal Pigment Epithelium.

  1993cites this paper
• Cooperative binding of the retinal rod G-protein, transducin, to light-activated rhodopsin.

  1993cites this paper
• 33P is preferable to 35S for labeling probes used in in situ hybridization.

  1993cites this paper
• PHOTOSENSORY TRANSDUCTION IN CILIATES. II. POSSIBLE ROLE OF G‐PROTEIN AND cGMP IN Stentor coeruleus

  1993cites this paper
• Tryptophan207 is involved in the GTP-dependent conformational switch in the alpha subunit of the G protein transducin: chymotryptic digestion patterns of the GTP gamma S and GDP-bound forms.

  1993cites this paper
• Identification of the alpha-subunits of rod and cone transducin in chicken photoreceptor cells.

  1993cites this paper
• CHAPTER 2 – STRUCTURE AND FUNCTION OF G PROTEINS

  1993cites this paper
• The molecular cloning of the squid (Loligo forbesi) visual Gq-alpha subunit and its expression in Saccharomyces cerevisiae.

  1993cites this paper
• X‐Arrestin: a new retinal arrestin mapping to the X chromosome

  1993cites this paper
• The molecular biology of taste transduction

  1993cites this paper
• Tryptophan207 is involved in the GTP-dependent conformational switch in the α subunit of the G protein transducin: Chymotryptic digestion patterns of the GTPγS and GDP-bound forms

  1993cites this paper
• Transgenic Mouse Studies of Retinal Degeneration: Expression of The β-Subunit of cGMP Phosphodiesterase and Transducin α-Subunits

  1993cites this paper
• Stimulation by nitric oxide of an NAD linkage to glyceraldehyde-3-phosphate dehydrogenase.

  1993cites this paper
• Molecular characterization of a novel retinal metabotropic glutamate receptor mGluR6 with a high agonist selectivity for L-2-amino-4-phosphonobutyrate.

  1993cites this paper
• Tryptophan W207 in transducin T alpha is the fluorescence sensor of the G protein activation switch and is involved in the effector binding.

  1993cites this paper
• Gustducin is a taste-cell-specific G protein closely related to the transducins

  1992cites this paper
• Regulation of retinal cGMP cascade by phosducin in bovine rod photoreceptor cells. Interaction of phosducin and transducin.

  1992cites this paper
• Identification of effector-activating residues of Gsα

  1992cites this paper
• Hormonal stimulation of adenylyl cyclase through Gi-protein βγ subunits

  1992cites this paper
• Detection of coincident signals by G proteins and adenylyl cyclase.

  1992cites this paper
• Lipid modification at the N terminus of photoreceptor G-protein α-subunit

  1992cites this paper
• A conserved retina-specific gene encodes a basic motif/leucine zipper domain.

  1992cites this paper
• Hormonal stimulation of adenylyl cyclase through Gi-protein beta gamma subunits.

  1992cites this paper
• A microsomal endoprotease that specifically cleaves isoprenylated peptides.

  1992cites this paper
• α Gustducin: A Taste Cell Specific G Protein Subunit Closely Related to the α Transducins

  1992cites this paper
• Domain mapping of the retinal cyclic GMP phosphodiesterase gamma-subunit. Function of the domains encoded by the three exons of the gamma-subunit gene.

  1992cites this paper
• Activated cGMP phosphodiesterase of retinal rods. A complex with transducin alpha subunit.

  1992cites this paper
• Enhancement of cholera toxin-catalyzed ADP-ribosylation by guanine nucleotide-binding proteins.

  1992cites this paper
• Lipid modification at the N terminus of photoreceptor G-protein alpha-subunit.

  1992cites this paper
• Identification of effector-activating residues of Gs alpha.

  1992cites this paper
• Signal Transducing G-Proteins: α Subunits

  1992cites this paper
• Amino acid-specific ADP-ribosylation: structural characterization and chemical differentiation of ADP-ribose-cysteine adducts formed nonenzymatically and in a pertussis toxin-catalyzed reaction.

  1992cites this paper
• Phylogeny and evolutionary rates of G protein α subunit genes

  1992cites this paper
• Carriers of the mouse rd gene have reduced levels of the beta subunit of the retinal cyclic GMP phosphodiesterase.

  1992cites this paper
• Phylogeny and evolutionary rates of G protein alpha subunit genes.

  1992cites this paper
• Sites of interaction between rod G-protein alpha-subunit and cGMP-phosphodiesterase gamma-subunit. Implications for the phosphodiesterase activation mechanism.

  1992cites this paper
• Characterization of the human rod transducin alpha-subunit gene.

  1992cites this paper
• The rod transducin alpha subunit amino terminus is heterogeneously fatty acylated.

  1992cites this paper
• The GTPase superfamily: conserved structure and molecular mechanism

  1991cites this paper
• Expression of G-Protein α-Subunit cDNA

  1991cites this paper
• The Effects of Chronic Ethanol Exposure of the Dopaminergic System of the Rat Brain

  1991cites this paper
• Structure and function of G proteins.

  1991cites this paper
• Analyzing the substrate specificity of Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase by co-expressing it with mammalian G protein alpha subunits in Escherichia coli.

  1991cites this paper
• On the origins and present state of the art of G protein research.

  1991cites this paper
• Structure and function of signal-transducing GTP-binding proteins.

  1991cites this paper
• Expression of G-protein alpha-subunit cDNA.

  1991cites this paper
• Structural heterogeneity of membrane receptors and GTP-binding proteins and its functional consequences for signal transduction.

  1991cites this paper
• Structural analysis of rod GTP-binding protein, Gt. Limited proteolytic digestion pattern of Gt with four proteases defines monoclonal antibody epitope.

  1991cites this paper
• Isolation and sequence analysis of TGA1 cDNAs encoding a tomato G protein alpha subunit.

  1991cites this paper
• Oncogene N-ras mediates selective inhibition of c-fos induction by nerve growth factor and basic fibroblast growth factor in a PC12 cell line

  1990cites this paper
• The gamma subunit of transducin is farnesylated.

  1990cites this paper
• Molecular cloning and characterization of GPA1, a G protein alpha subunit gene from Arabidopsis thaliana.

  1990cites this paper
• Molecular cloning, primary structure, and orientation of the vertebrate photoreceptor cell protein peripherin in the rod outer segment disk membrane.

  1990cites this paper
• CHAPTER 4 – Organization of Genes Coding for G-Protein α Subunits in Higher and Lower Eukaryotes

  1990cites this paper
• Two G protein oncogenes in human endocrine tumors.

  1990cites this paper
• Identification of monoclonal antibody 4A-binding site on the transducin alpha subunit. Immunoblotting of submaxillary Arg-C protease fragments of transducin.

  1990cites this paper
• CHAPTER 5 – Structural, Immunobiological, and Functional Characterization of Guanine Nucleotide-Binding Protein Go

  1990cites this paper
• The p38 and p34 polypeptides of growth cone particle membranes are the α- and β-subunits of G proteins

  1990cites this paper
• Transduction of receptor signal into modulation of effector activity by G proteins: the first 20 years or so …

  1990cites this paper
• Sites of interaction in the complex between beta- and gamma-subunits of transducin.

  1990cites this paper
• Multiple forms of Go alpha mRNA: analysis of the 3'-untranslated regions.

  1990cites this paper
• Receptor-effector coupling by G proteins.

  1990cites this paper
• The p38 and p34 polypeptides of growth cone particle membranes are the alpha- and beta-subunits of G proteins.

  1990cites this paper
• Visual transduction in rod outer segments.

  1990cites this paper
• Guanine nucleotide-binding proteins (G proteins) in activation of adenylyl cyclase: lessons learned from cholera and "travelers' diarrhea".

  1989cites this paper
• Evidence for oligomeric forms of transducins alpha subunit: formation of intermolecular alpha-alpha disulfide linkages.

  1989cites this paper
• G proteins in Aplysia: biochemical characterization and regional and subcellular distribution.

  1989cites this paper