Peripheral urocortin delays gastric emptying: role of CRF receptor 2.

No abstract is available for this paper.

• Publication year

  1999

• Venue

  American Journal of Physiology - Gastrointestinal and Liver Physiology

• Publication date

  1999-04-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1152/ajpgi.1999.276.4.G867PMID 29597626
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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  1998influential reference
• Central CRF inhibits gastric emptying of a nutrient solid meal in rats: the role of CRF2receptors.

  1998cited by this paper
• Central CRF inhibits gastric emptying of a nutrient solid meal in rats: the role of CRF2 receptors.

  1998cited by this paper
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  1998cited by this paper
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  1996cited by this paper
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  1996cited by this paper
• Neuronal pathways involved in abdominal surgery-induced gastric ileus in rats.

  1996cited by this paper
• In vivo and in vitro characterization of antalarmin, a nonpeptide corticotropin-releasing hormone (CRH) receptor antagonist: suppression of pituitary ACTH release and peripheral inflammation.

  1996influential reference
• Cloning and characterization of human urocortin.

  1996influential reference
• Corticotrophin-releasing factor receptors: from molecular biology to drug design.

  1996cited by this paper
• Corticotropin-releasing hormone (CRH) receptors in the mesenteric small arteries of rats resemble the (2)-subtype.

  1996cited by this paper
• Passage of peptides across the blood-brain barrier: pathophysiological perspectives.

  1996cited by this paper
• Design and synthesis of a series of non-peptide high-affinity human corticotropin-releasing factor1 receptor antagonists.

  1996cited by this paper
• Intravenous interleukin-1-beta-induced inhibition of gastric emptying: involvement of central corticotrophin-releasing factor and prostaglandin pathways in rats.

  1996cited by this paper
• Cloning and characterization of human urocortin [published erratum appears in Endocrinoogy 1996 Sep;137(9):3896]

  1996cited by this paper
• Cloning and characterization of a functionally distinct corticotropin-releasing factor receptor subtype from rat brain.

  1995cited by this paper
• A sauvagine/corticotropin-releasing factor receptor expressed in heart and skeletal muscle.

  1995cited by this paper
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  1995cited by this paper
• The Role of CRF in Behavioral Aspects of Stress

  1995cited by this paper
• Identification of a second corticotropin-releasing factor receptor gene and characterization of a cDNA expressed in heart.

  1995cited by this paper
• Potent, structurally constrained agonists and competitive antagonists of corticotropin-releasing factor.

  1995influential reference
• Urocortin, a mammalian neuropeptide related to fish urotensin I and to corticotropin-releasing factor

  1995influential reference
• Fedotozine reversal of peritoneal-irritation-induced ileus in rats: possible peripheral action on sensory afferents.

  1994cited by this paper
• Role of CRF in Stress‐Related Alterations of Gastric and Colonic Motor Function a

  1993cited by this paper
• Corticotropin‐Releasing Factor Binding Sites Undergo Axonal Transport in the Rat Vagus Nerve

  1992cited by this paper
• Abdominal surgery-induced delayed gastric emptying in rats: role of CRF and sensory neurons.

  1992cited by this paper
• Biphasic changes in hypothalamo-pituitary-adrenal function during the early recovery period after major abdominal surgery.

  1991cited by this paper
• Physiology and pharmacology of corticotropin-releasing factor.

  1991cited by this paper
• Abdominal Surgery‐ and Trephination‐Induced Delay in Gastric Emptying is Prevented by Intracisternal Injection of CRF Antagonist in the Rat

  1991cited by this paper
• Evolutionary aspects in the peripheral peptidergic signals: CRF-like peptides and modulation of G.I. functions.

  1991cited by this paper
• Differential antagonist activity of alpha-helical corticotropin-releasing factor9-41 in three bioassay systems.

  1991cited by this paper
• Autocrine or paracrine inflammatory actions of corticotropin-releasing hormone in vivo.

  1991cited by this paper
• Pituitary-adrenal and vagus modulation of sauvagine- and CRF-induced inhibition of gastric emptying in rats.

  1990cited by this paper
• Gastrointestinal motor effects of corticotropin-releasing factor in mice.

  1990cited by this paper
• Inhibition of Gastric Motor Function by Circulating Corticotropin‐Releasing Factor in Anesthetized Rats

  1990cited by this paper
• Cholecystokinin inhibits gastric motility and emptying via a capsaicin-sensitive vagal pathway in rats.

  1988cited by this paper
• Stress-induced gastrointestinal secretory and motor responses in rats are mediated by endogenous corticotropin-releasing factor.

  1988cited by this paper
• Central nervous system effects of corticotropin-releasing factor on gastrointestinal transit in the rat.

  1988cited by this paper
• Central nervous system action of corticotropin-releasing factor to inhibit gastric emptying in rats.

  1987cited by this paper
• Corticotropin-releasing factor directly mediates colonic responses to stress.

  1987cited by this paper
• Peptide YY release by fatty acids is sufficient to inhibit gastric emptying in dogs.

  1986cited by this paper
• Corticotropin-releasing factor inhibits gastric emptying in dogs.

  1985cited by this paper
• Complete amino acid sequence of urotensin I, a hypotensive and corticotropin-releasing neuropeptide from Catostomus.

  1982cited by this paper
• Characterization of a 41-residue ovine hypothalamic peptide that stimulates secretion of corticotropin and beta-endorphin.

  1982cited by this paper
• Characterization of a 41-residue ovine hypothalamic peptide that stimulates secretion of corticotropin and beta-endorphin

  1981cited by this paper

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• Corticotropin-releasing factor and acute post-operative gut function in truamatic abdominal injury and elective abdominal surgery

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• Neuroendocrine control of the gut during stress: corticotropin-releasing factor signaling pathways in the spotlight.

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• Corticotropin-releasing factor inhibition of sheep fetal colonic contractility: mechanisms to prevent meconium passage in utero.

  2007cites this paper
• Urocortin I is present in the enteric nervous system and exerts an excitatory effect via cholinergic and serotonergic pathways in the rat colon.

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• Corticotropin-releasing factor receptors and stress-related alterations of gut motor function.

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• Urocortins and the regulation of gastrointestinal motor function and visceral pain.

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• Ghrelin, appetite, and gastric motility: the emerging role of the stomach as an endocrine organ

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• Isolation and Characterisation of the Corticotropin Releasing Factor Receptor 1 (CRFR1) Gene in a Teleost Fish, Fugu rubripes

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• Mechanisms and treatment of postoperative ileus.

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• Stimulation of rat pancreatic exocrine secretion by urocortin and corticotropin releasing factor.

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• Differential profile of CRF receptor distribution in the rat stomach and duodenum assessed by newly developed CRF receptor antibodies

  2003cites this paper
• The effect of urocortin on ingestive behaviours and brain Fos immunoreactivity in mice

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• Corticotropin-releasing factor receptor 1-deficient mice do not develop postoperative gastric ileus.

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• Effects of exogenous corticotropin-releasing factor on antropyloroduodenal motility and appetite in humans

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• The CRF peptide family and their receptors: yet more partners discovered.

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  2002cites this paper
• Gonadotropin-releasing-hormone-receptor antagonists.

  2001cites this paper
• Physiological roles of corticotropin-releasing hormone receptor type 2.

  2001cites this paper
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  2001cites this paper
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  2001cites this paper
• Peripheral urocortin inhibits gastric emptying and food intake in mice: differential role of CRF receptor 2.

  2001cites this paper
• Gastroduodenal motility.

  2000cites this paper
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  2000cites this paper
• Peptidergic regulation of gastrointestinal motility in rodents.

  2000cites this paper
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  2000cites this paper
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  2000cites this paper
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  2000cites this paper
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  2000cites this paper
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  1999cites this paper
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  1999cites this paper