T. Nozu

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Aliases
T Nozu, T. Nozu, Tsukasa Nozu
Publication record
109 papers · 1,726 citations · H-index 22

PAPERS

Bombesin improves visceral hypersensitivity and colonic hyperpermeability via BB1 receptor-dependent multi-pathway mechanisms in a rat model of irritable bowel syndrome.
20260 citationsauthor #1
Brain AMPK signaling improves intestinal barrier function through brain orexin and the vagal pathway in rats.
20251 citationsauthor #2
Carnosine improves colonic hyperpermeability through the brain histamine H1 receptor, basal forebrain cholinergic neurons, adenosine A2B receptors and vagus nerve in rats.
20251 citationsauthor #2
Irisin prevents visceral hypersensitivity and colonic hyperpermeability in a rat model of irritable bowel syndrome.
20253 citationsauthor #1
The neurotensin receptor 1 agonist PD149163 alleviates visceral hypersensitivity and colonic hyperpermeability in rat irritable bowel syndrome model
20244 citationsauthor #1
Splenectomy prevents brain orexin, ghrelin, or oxytocin but not GLP‐1‐induced improvement of intestinal barrier function in rats
20240 citationsauthor #2
Brain histamine improves colonic hyperpermeability through the basal forebrain cholinergic neurons, adenosine A2B receptors and vagus nerve in rats.
20244 citationsauthor #2
Tranilast alleviates visceral hypersensitivity and colonic hyperpermeability by suppressing NLRP3 inflammasome activation in irritable bowel syndrome rat models.
20246 citationsauthor #1
Prostaglandin I2 suppresses the development of gut-brain axis disorder in irritable bowel syndrome in rats.
20232 citationsauthor #3
Centrally administered GLP-1 analogue improves intestinal barrier function through the brain orexin and the vagal pathway in rats.
202312 citationsauthor #2
Brain Neuropeptides, Neuroinflammation, and Irritable Bowel Syndrome
202317 citationsauthor #2
Adult-onset Periodic Fever, Aphthous Stomatitis, Pharyngitis and Cervical Adenitis Syndrome Responsive to Colchicine
20231 citationsauthor #1
Ghrelin prevents lethality in a rat endotoxemic model through central effects on the vagal pathway and adenosine A2B signaling
20231 citationsauthor #2
Imeglimin prevents visceral hypersensitivity and colonic hyperpermeability in irritable bowel syndrome rat model.
20235 citationsauthor #1
Phlorizin attenuates postoperative gastric ileus in rats
20233 citationsauthor #1
Pathophysiological Commonality Between Irritable Bowel Syndrome and Metabolic Syndrome: Role of Corticotropin-releasing Factor–Toll-like Receptor 4–Proinflammatory Cytokine Signaling
202222 citationsauthor #1
Peripheral apelin mediates visceral hypersensitivity and impaired gut barrier in a rat irritable bowel syndrome model.
202211 citationsauthor #1
Activation of basal forebrain cholinergic neurons improves colonic hyperpermeability through the vagus nerve and adenosine A2B receptors in rats.
20225 citationsauthor #2
Oxytocin acts centrally in the brain to improve leaky gut through the vagus nerve and a cannabinoid signaling in rats.
202216 citationsauthor #2
A patient with familial Mediterranean fever mimicking diarrhea-dominant irritable bowel syndrome who successfully responded to treatment with colchicine: a case report
20221 citationsauthor #5
Centrally administered butyrate improves gut barrier function, visceral sensation and septic lethality in rats.
202122 citationsauthor #2
Central regulatory mechanisms of visceral sensation in response to colonic distension with special reference to brain orexin.
20218 citationsauthor #3
Phlorizin attenuates visceral hypersensitivity and colonic hyperpermeability in a rat model of irritable bowel syndrome.
202117 citationsauthor #1
EMA401, an angiotensin II type 2 receptor antagonist blocks visceral hypersensitivity and colonic hyperpermeability in rat model of irritable bowel syndrome.
20218 citationsauthor #1
Activation of central adenosine A2B receptors mediate brain ghrelin-induced improvement of intestinal barrier function through the vagus nerve in rats.
202117 citationsauthor #2
Ghrelin acts in the brain to block colonic hyperpermeability in response to lipopolysaccharide through the vagus nerve.
202022 citationsauthor #2
Imipramine improves visceral sensation and gut barrier in rat models of irritable bowel syndrome.
20209 citationsauthor #1
5-HT2A receptors but not cannabinoid receptors in the central nervous system mediate levodopa-induced visceral antinociception in conscious rats
20206 citationsauthor #2
Losartan improves visceral sensation and gut barrier in a rat model of irritable bowel syndrome
202016 citationsauthor #1
Brain orexin improves intestinal barrier function via the vagal cholinergic pathway.
202028 citationsauthor #2
Adenosine A1 receptor agonist induces visceral antinociception via 5-HT1A, 5-HT2A, dopamine D1 or cannabinoid CB1 receptors, and the opioid system in the central nervous system.
202010 citationsauthor #2
Centrally administered orexin prevents lipopolysaccharide and colchicine induced lethality via the vagal cholinergic pathway in a sepsis model in rats.
20208 citationsauthor #2
Central oxytocin signaling mediates the central orexin-induced visceral antinociception through the opioid system in conscious rats.
20198 citationsauthor #2
Grape Seed Extract Eliminates Visceral Allodynia and Colonic Hyperpermeability Induced by Repeated Water Avoidance Stress in Rats
201922 citationsauthor #2
Dehydroepiandrosterone sulfate improves visceral sensation and gut barrier in a rat model of irritable bowel syndrome
201917 citationsauthor #1
[Mechanism of visceral hypersensitivity in patients with irritable bowel syndrome].
20191 citationsauthor #1
Butyrate inhibits visceral allodynia and colonic hyperpermeability in rat models of irritable bowel syndrome
201941 citationsauthor #1
Pioglitazone improves visceral sensation and colonic permeability in a rat model of irritable bowel syndrome.
201914 citationsauthor #1
Glucagon‐like peptide‐1 analog, liraglutide, improves visceral sensation and gut permeability in rats
201848 citationsauthor #1
Altered colonic sensory and barrier functions by CRF: roles of TLR4 and IL-1.
201848 citationsauthor #1
Role of the cannabinoid signaling in the brain orexin- and ghrelin-induced visceral antinociception in conscious rats.
201810 citationsauthor #2
Lovastatin inhibits visceral allodynia and increased colonic permeability induced by lipopolysaccharide or repeated water avoidance stress in rats
201822 citationsauthor #1
Ghrelin acts centrally to induce an antinociceptive action during colonic distension through the orexinergic, dopaminergic and opioid systems in conscious rats.
201820 citationsauthor #2
Metformin inhibits visceral allodynia and increased gut permeability induced by stress in rats
201825 citationsauthor #1
A hypothesis for understanding mechanisms of normal and abnormal behavior states based on operation hypothesis
20181 citationsauthor #6
Cold Exposure Related Fever with an Mediterranean Fever (MEFV) Gene Mutation
20176 citationsauthor #2
A glucagon-like peptide-1 analog,
20170 citationsauthor #1
Repeated water avoidance stress induces visceral hypersensitivity: Role of interleukin‐1, interleukin‐6, and peripheral corticotropin‐releasing factor
201733 citationsauthor #1
Bullous pemphigoid and percutaneous endoscopic gastrostomy
20160 citationsauthor #1
Adenosine A1 receptors mediate the intracisternal injection of orexin-induced antinociceptive action against colonic distension in conscious rats.
201616 citationsauthor #2
Levodopa acts centrally to induce an antinociceptive action against colonic distension through activation of D2 dopamine receptors and the orexinergic system in the brain in conscious rats.
20169 citationsauthor #2
Water avoidance stress induces visceral hyposensitivity through peripheral corticotropin releasing factor receptor type 2 and central dopamine D2 receptor in rats
20169 citationsauthor #1
[Diagnosis at a Glance.]
20161 citationsauthor #1
Lipopolysaccharide induces visceral hypersensitivity: role of interleukin-1, interleukin-6, and peripheral corticotropin-releasing factor in rats
201642 citationsauthor #1
Retropharyngeal Calcific Tendinitis.
20151 citationsauthor #1
Brainstem control of locomotion and muscle tone with special reference to the role of the mesopontine tegmentum and medullary reticulospinal systems
2015196 citationsauthor #3
Screening for Major Depressive Disorder with the Patient Health Questionnaire (PHQ-9 and PHQ-2) in an Outpatient Clinic Staffed by Primary Care Physicians in Japan: A Case Control Study
201533 citationsauthor #4
Colorectal distention induces acute and delayed visceral hypersensitivity: role of peripheral corticotropin-releasing factor and interleukin-1 in rats
20159 citationsauthor #1
Corticotropin-releasing factor receptor type 1 and type 2 interaction in irritable bowel syndrome
201550 citationsauthor #1
Antinociceptive action against colonic distension by brain orexin in conscious rats.
201526 citationsauthor #2
Involvement of the dopaminergic system in the central orexin-induced antinociceptive action against colonic distension in conscious rats.
201521 citationsauthor #2
An Adult Patient With Cyclic Vomiting Syndrome Successfully Treated With Oral Sumatriptan
20147 citationsauthor #4
A balance theory of peripheral corticotropin-releasing factor receptor type 1 and type 2 signaling to induce colonic contractions and visceral hyperalgesia in rats.
201434 citationsauthor #1
Urocortin 2 blocks the suppression of gastric antral contractions induced by lipopolysaccharide in freely moving conscious rats.
20143 citationsauthor #1
Water-avoidance stress enhances gastric contractions in freely moving conscious rats: role of peripheral CRF receptors
201418 citationsauthor #1
Peripheral corticotropin‐releasing factor (CRF) induces stimulation of gastric contractions in freely moving conscious rats: role of CRF receptor types 1 and 2
201320 citationsauthor #1
7. Functional Abdominal Pain Syndrome
20130 citationsauthor #1
Mo1988 Inhibition of Corticotropin Releasing Factor (CRF) Receptor Type 2 Signaling Enhances Peripheral CRF-Induced Stimulation of Colonic Contractions in Conscious Rats
20131 citationsauthor #1
[Functional gastrointestinal disorders (FGID): progress in diagnosis and treatments. Topic II. Current status and future prospective of medical care of the representative disorders; 7. Functional abdominal pain syndrome].
20130 citationsauthor #1
A higher frequency of lumbar ossification of the posterior longitudinal ligament in elderly in an outpatient clinic in Japan
20137 citationsauthor #4
Tu1974 Endogenous IL-1 Mediates the LPS-Induced Inhibition of Gastric Motility in Conscious Rats
20120 citationsauthor #2
Endogenous orexin-A in the brain mediates 2-deoxy-d-glucose-induced stimulation of gastric motility in freely moving conscious rats
201221 citationsauthor #1
Chronic Right Lower Abdominal Pain Due to Lumbar Ossification of the Posterior Longitudinal Ligament
20123 citationsauthor #4
High rate of smoking in female patients with Mondor’s disease in an outpatient clinic in Japan
20127 citationsauthor #3
IL-1 Receptor Antagonist Blocks the Lipopolysaccharide-Induced Inhibition of Gastric Motility in Freely Moving Conscious Rats
201210 citationsauthor #2
Peritoneal loose body.
20127 citationsauthor #1
Epiploic appendagitis as an uncommon cause of lower abdominal pain
20120 citationsauthor #8
Role of brain orexin in the pathophysiology of functional gastrointestinal disorders
201133 citationsauthor #2
The rate of polymyalgia rheumatica (PMR) and remitting seronegative symmetrical synovitis with pitting edema (RS3PE) syndrome in a clinic where primary care physicians are working in Japan
201136 citationsauthor #4
Severe hyponatremia in association with I(131) therapy in a patient with metastatic thyroid cancer.
201120 citationsauthor #1
Modulatory effects of the GABAergic basal ganglia neurons on the PPN and the muscle tone inhibitory system in cats.
201141 citationsauthor #3
Visceral sensation and irritable bowel syndrome; with special reference to comparison with functional abdominal pain syndrome
201116 citationsauthor #1
Central orexin-A increases colonic motility in conscious rats.
201126 citationsauthor #1
Bullous pemphigoid and percutaneous endoscopic gastrostomy.
20108 citationsauthor #1
Characteristics in patients with headache in an outpatient clinic in Japan
201021 citationsauthor #5
Acquired factor V inhibitor in a patient with a mechanical aortic valve under warfarin therapy.
20108 citationsauthor #1
Idiopathic spontaneous intramural hematoma of the colon: a case report and review of the literature
200913 citationsauthor #1
Clinical characteristics of asymptomatic esophagitis
200844 citationsauthor #1
Emphysematous cystitis with air bubbles in the inferior vena cava
20084 citationsauthor #1
Repetitive rectal painful distention induces rectal hypersensitivity in patients with irritable bowel syndrome
200616 citationsauthor #1
Fitz-Hugh-Curtis syndrome.
200622 citationsauthor #1
Corticotropin-releasing factor induces rectal hypersensitivity after repetitive painful rectal distention in healthy humans
200641 citationsauthor #1
Peripheral injection of sauvagine prevents repeated colorectal distension-induced visceral pain in female rats.
200541 citationsauthor #4
Image of the month. Isolated dissection of the superior mesenteric artery.
20044 citationsauthor #1
Image of the month: David M. Warshauer, section editor
200411 citationsauthor #1
Inadequate health care-seeking behavior of Japanese patients with functional gastrointestinal disorders: a preliminary survey
20023 citationsauthor #1
Peripheral urocortin delays gastric emptying: role of CRF receptor 2.
199914 citationsauthor #1
Peripheral urocortin delays gastric emptying: role of CRF receptor 2.
199978 citationsauthor #1
Intracisternal or microinjection of TRH into DMN does not activate non-adrenergic, non-cholinergic inhibitory (NANC) neurons of the rat stomach
19981 citationsauthor #1
Peripheral urocortin- and CRF-induced gastric stasis: Role of CRF2 receptor subtype in rats
19980 citationsauthor #1

TIMELINE

1992 43 citations

1994 0 citations

1995 30 citations

1998 4 citations

1999 92 citations

2002 3 citations

2004 15 citations

2005 41 citations

2006 79 citations

2008 48 citations

2009 13 citations

2010 37 citations

2011 172 citations

2012 48 citations

2013 28 citations

2014 62 citations

2015 336 citations

2016 77 citations

2017 39 citations

2018 174 citations

2019 103 citations

2020 99 citations

2021 72 citations

2022 55 citations

2023 41 citations

2024 14 citations

2025 5 citations

2026 0 citations

T. Nozu

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