Partial ATP depletion induces Fas- and caspase-mediated apoptosis in MDCK cells.

No abstract is available for this paper.

• Publication year

  1999

• Venue

  AJP - Renal Physiology

• Publication date

  1999-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1152/ajprenal.1999.276.6.F837PMID 29591383
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Graded ATP depletion can cause necrosis or apoptosis of cultured mouse proximal tubular cells.

  1998influential reference
• Caspases: the executioners of apoptosis.

  1997cited by this paper
• Altered ceramide and sphingosine expression during the induction phase of ischemic acute renal failure.

  1997cited by this paper
• Inhibition of interleukin 1beta converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage.

  1997cited by this paper
• Tissue-specific Pattern of Stress Kinase Activation in Ischemic/Reperfused Heart and Kidney*

  1997cited by this paper
• Recent advances in understanding mechanisms of renal tubular injury.

  1997influential reference
• Role of caspases (ICE/CED 3 proteases) in DNA damage and cell death in response to a mitochondrial inhibitor, antimycin A.

  1997cited by this paper
• Tight Junction Proteins Form Large Complexes and Associate with the Cytoskeleton in an ATP Depletion Model for Reversible Junction Assembly*

  1997cited by this paper
• Intracellular ATP levels determine cell death fate by apoptosis or necrosis.

  1997cited by this paper
• Long-term survival of limb allografts after weaning of cyclosporine: possible role of microchimerism.

  1997cited by this paper
• Internucleosomal DNA cleavage triggered by plasma membrane damage during necrotic cell death. Involvement of serine but not cysteine proteases.

  1997cited by this paper
• Intracellular Adenosine Triphosphate (ATP) Concentration: A Switch in the Decision Between Apoptosis and Necrosis

  1997cited by this paper
• Apoptosis by death factor.

  1997cited by this paper
• Role of ICE-like proteases in endothelial cell hypoxic and reperfusion injury.

  1997cited by this paper
• Apoptosis in the mammalian kidney: incidence, effectors, and molecular control in normal development and disease states.

  1997cited by this paper
• Tyrosine phosphorylation in DNA damage and cell death in hypoxic injury to LLC-PK1 cells.

  1997cited by this paper
• Renal stress response and acute renal failure.

  1997influential reference
• Role of reactive oxygen metabolites in DNA damage and cell death in chemical hypoxic injury to LLC-PK1 cells.

  1996cited by this paper
• Apoptosis in human kidney allografts.

  1996cited by this paper
• Detection of apoptosis at the single-cell level by direct incorporation of fluorescein-dUTP in DNA strand breaks.

  1996cited by this paper
• Human ICE/CED-3 protease nomenclature.

  1996cited by this paper
• Acceleration of recovery in acute renal failure: from cellular mechanisms of tubular repair to innovative targeted therapies.

  1996cited by this paper
• Growth factors and apoptosis in neonatal ureteral obstruction.

  1996cited by this paper
• Regulation of Fas and Fas ligand expression in cultured murine renal cells and in the kidney during endotoxemia.

  1996cited by this paper
• Mechanisms of apoptosis and its potential role in renal tubular epithelial cell injury.

  1996influential reference
• The molecular biology of apoptosis.

  1996cited by this paper
• Tissue remodeling during tumor necrosis factor-induced apoptosis in LLC-PK1 renal epithelial cells.

  1996cited by this paper
• Uninephrectomy reduces apoptotic cell death and enhances renal tubular cell regeneration in ischemic ARF in rats.

  1996cited by this paper
• Involvement of ICE family proteases in apoptosis induced by reoxygenation of hypoxic hepatocytes.

  1996cited by this paper
• Expression of apoptosis-related molecules in acute renal injury.

  1996cited by this paper
• Role of apoptosis in development of the ascending thin limb of the loop of Henle in rat kidney.

  1996cited by this paper
• Endonuclease induced DNA damage and cell death in chemical hypoxic injury to LLC-PK1 cells.

  1996cited by this paper
• Apoptosis and loss of renal tissue in polycystic kidney diseases.

  1995cited by this paper
• Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl

  1995cited by this paper
• Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)

  1995cited by this paper
• The death domain: a module shared by proteins with diverse cellular functions.

  1995cited by this paper
• ATP depletion: a novel method to study junctional properties in epithelial tissues. II. Internalization of Na+,K(+)-ATPase and E-cadherin.

  1994cited by this paper
• II. Internalization of Na + ,K + -ATPase and E-cadherin

  1994cited by this paper
• ATP depletion: a novel method to study junctional properties in epithelial tissues. I. Rearrangement of the actin cytoskeleton.

  1994cited by this paper
• Apoptosis and the kidney.

  1994cited by this paper
• Apoptosis and cell desquamation in repair process of ischemic tubular necrosis

  1993cited by this paper
• Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

  1992cited by this paper
• Morphologic, biochemical, and molecular evidence of apoptosis during the reperfusion phase after brief periods of renal ischemia.

  1992cited by this paper
• Apoptosis in metanephric development

  1992cited by this paper
• Effect of reversible ATP depletion on tight-junction integrity in LLC-PK1 cells.

  1991cited by this paper
• Apoptosis: A Basic Biological Phenomenon with Wide-ranging Implications in Tissue Kinetics

  1972cited by this paper

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