Transient outwardly rectifying A currents are involved in the firing rate response to altered CO2 in chemosensitive locus coeruleus neurons from neonatal rats.

No abstract is available for this paper.

• Publication year

  2013

• Venue

  American Journal of Physiology. Regulatory Integrative and Comparative Physiology

• Publication date

  2013-10-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1152/ajpregu.00029.2013PMID 23948777PMCID PMC3798795
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2011influential reference
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