Associative visual agnosia and alexia without prosopagnosia.

Disagreement over the neuroanatomical substrate of associative visual agnosia encompasses such basic issues as: (1) the necessity for bilateral lesions; (2) the intrahemispheric locus of damage; and (3) the roles of disconnection versus cortical damage. We examined three patients whose associative visual agnosia encompassed objects and printed words but spared faces. CAT scans revealed unilateral dominant occipitotemporal strokes. CAT scans of four previously reported cases with this same profile of associative agnosia were obtained. Dominant parahippocampal, fusiform and lingual gyri were the most extensively damaged cortical regions surveyed and were involved in all cases. Of white matter tracts surveyed, only temporal white matter including inferior longitudinal fasciculus was severely and universally involved. Splenium of the corpus callosum was frequently but not always involved. We conclude there is a form of associative visual agnosia with agnosia for objects and printed words but sparing face recognition which has a characteristic unilateral neuropathology. Damage or disconnection of dominant parahippocampal, fusiform and lingual gyri is the necessary and sufficient lesion.

• Publication year

  1994

• Venue

  Cortex; a journal devoted to the study of the nervous system and behavior

• Publication date

  1994-09-01

• Fields of study

  Medicine, Psychology

• Identifiers
  DOI 10.1016/S0010-9452(13)80337-1PMID 7805382
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Parts and Wholes in Face Recognition

  1993cited by this paper
• Dissociation of Object and Spatial Vision in Human Extrastriate Cortex: Age-Related Changes in Activation of Regional Cerebral Blood Flow Measured with [15 O]Water and Positron Emission Tomography

  1992cited by this paper
• Visual associative agnosia and optic aphasia. A single case study and a review of the syndromes.

  1992cited by this paper
• Functional neuroanatomy of face and object processing. A positron emission tomography study.

  1992cited by this paper
• Functional Associations among Human Posterior Extrastriate Brain Regions during Object and Spatial Vision

  1992cited by this paper
• Dissociation of object and spatial visual processing pathways in human extrastriate cortex.

  1991cited by this paper
• Visual topography of area TEO in the macaque

  1991cited by this paper
• Cognitive Neuropsychology: Patterns of Co-occurrence Among the Associative Agnosias: Implications for Visual Object Representation

  1991cited by this paper
• Visual Object Representation: Interpreting Neurophysiological Data within a Computational Framework

  1990cited by this paper
• Brain Imaging

  1990cited by this paper
• Visual Agnosia: Disorders of Object Recognition and What They Tell Us about Normal Vision

  1990cited by this paper
• Preserved object recognition and reading comprehension in optic aphasia.

  1989cited by this paper
• [Disconnection and recognition of faces. A case with lesions of the left visual cortex and the splenium].

  1988cited by this paper
• Dissociable visual and spatial impairments following right posterior cerebral lesions: clinical, neuropsychological and anatomical evidence.

  1987cited by this paper
• The pattern of neuropsychological impairment associated with left posterior cerebral artery infarcts.

  1987cited by this paper
• Visual associative agnosia: a clinico-anatomical study of a single case.

  1986cited by this paper
• Multimodal agnosia after unilateral left hemisphere lesion

  1986cited by this paper
• Lexical processing in the absence of explicit word identification: Evidence from a letter-by-letter reader

  1986cited by this paper
• The assessment of aphasia and related disorders By Harold Goodglass and edith kaplan philadelphia, lea & febiger, 1983 illustrated, $27.50 (package)

  1984cited by this paper
• Residual reading capability in a patient with alexia without agraphia.

  1984cited by this paper
• [Visual and tactile agnosia].

  1984cited by this paper
• The anatomic basis of pure alexia

  1983cited by this paper
• Object vision and spatial vision: Two cortical pathways

  1983cited by this paper
• The anatomical basis of visual agnosia

  1983cited by this paper
• A memory system in the monkey.

  1982cited by this paper
• Two cortical visual systems

  1982cited by this paper
• [Associative visual agnosia: role of the left hemisphere in visual perception (author's transl)].

  1981cited by this paper
• Sensory-specific and fractional disorders of recent memory in man. I. Isolated loss of visual recent memory.

  1980cited by this paper
• The locus of the posterior subdivision of the inferotemporal visual learning area in the monkey

  1980cited by this paper
• [Visual agnosia without right hemianopia in a right-handed patient (author's transl)].

  1980cited by this paper
• The anatomic basis of visual agnosia

  1979cited by this paper
• AN ATLAS OF THE HUMAN BRAIN FOR COMPUTERIZED TOMOGRAPHY.

  1978cited by this paper
• Visual agnosia-prosopagnosia. A clinicopathologic correlation.

  1974cited by this paper
• Comprehension in alexia.

  1973cited by this paper
• Visual agnosia: a single case report.

  1971cited by this paper
• Further evidence on the locus of the visual area in the temporal lobe of the monkey.

  1969cited by this paper
• Disconnexion syndromes in animals and man. I.

  1965cited by this paper
• The association value of random shapes.

  1959cited by this paper
• Tactile thought, with special reference to the blind.

  1953cited by this paper
• UNILATERAL CEREBRAL DOMINANCE AS RELATED TO MIND BLINDNESS: MINIMAL LESION CAPABLE OF CAUSING VISUAL AGNOSIA FOR OBJECTS

  1937cited by this paper

• Seeing and visualizing across the hemispheres.

  2025cites this paper
• Neuropsychological Diagnosis and Assessment of Alexia: A Mixed-Methods Study

  2024cites this paper
• Clinical and structural disconnectome evaluation in a case of optic aphasia

  2024cites this paper
• Learning From Mistakes: Cognitive and Metabolic Correlates of Errors on Picture Naming in the Alzheimer’s Disease Spectrum

  2022cites this paper
• Cerebral White Matter Tract Anatomy.

  2022cites this paper
• The inferior longitudinal fasciculus: anatomy, function and surgical considerations.

  2021cites this paper
• Running head: FMRI OF WORD READING AND PICTURE NAMING 1 Considering unique, shared, and dominant brain activation in the Visual Word Form Area and Lateral Occipital Cortex: A comparison of separate and combined word reading and picture naming

  2021cites this paper
• Unique, shared, and dominant brain activation in Visual Word Form Area and Lateral Occipital Complex during reading and picture naming

  2021cites this paper
• From Action to Cognition: Neural Reuse, Network Theory and the Emergence of Higher Cognitive Functions

  2021cites this paper
• Does mental rotation emulate motor processes? An electrophysiological study of objects and body parts

  2021cites this paper
• Visual Agnosia

  2020cites this paper
• Properties of cross-modal occipital responses in early blindness: An ALE meta-analysis

  2019cites this paper
• Memory impairment in patients with spleen deficiency syndrome: Evidence from a resting-state fMRI study

  2019cites this paper
• Higher Cortical Visual Disorders.

  2019cites this paper
• Disorders of Higher Cortical Visual Function

  2019cites this paper
• Functional connectivity and the failure to retrieve meaning from shape in visual object agnosia

  2019cites this paper
• Functional compensation of the left inferior longitudinal fasciculus for picture naming

  2018cites this paper
• Hemifield coding in ventral object-sensitive areas - Evidence from visual hemiagnosia.

  2018cites this paper
• Congenital prosopagnosia without object agnosia? A literature review

  2018cites this paper
• The Fusiform and Occipital Face Areas Can Process a Nonface Category Equivalently to Faces

  2018cites this paper
• Cortical Brain Changes in Patients With Locked-In Syndrome Experiencing Hallucinations and Delusions

  2018cites this paper
• Functional Anatomy of the Inferior Longitudinal Fasciculus: From Historical Reports to Current Hypotheses

  2018cites this paper
• isual form-processing deficits : A global clinical classification

  2017cites this paper
• The Visual Agnosias and Related Disorders

  2017cites this paper
• [Hyperfamiliarity for faces in temporal lobe epilepsy].

  2015cites this paper
• Emergence delirium with transient associative agnosia and expressive aphasia reversed by flumazenil in a pediatric patient.

  2015cites this paper
• Visual form-processing deficits : A global clinical classification

  2014cites this paper
• FAMILAR FACES : THE EFFECTS OF EXPERIENCE ON CHANGE BLINDNESS

  2014cites this paper
• Sex differences in cortical thickness and their possible genetic and sex hormonal underpinnings.

  2014cites this paper
• Higher Cortical Visual Deficits

  2014cites this paper
• Visual form-processing deficits: a global clinical classification.

  2014cites this paper
• Visual form-processing deficits: a global clinical classification

  2014cites this paper
• Cortical' signs and symptoms

  2012cites this paper
• 視覚失語に移行した連合型視覚失認の 1 例

  2012cites this paper
• fMRI of Human Visual Pathways

  2011cites this paper
• Neural deficits in second language reading: fMRI evidence from Chinese children with English reading impairment

  2011cites this paper
• Complementary neural representations for faces and words: A computational exploration

  2011cites this paper
• 25 – Posterior Cerebral Artery Disease

  2011cites this paper
• A new selective developmental deficit: Impaired object recognition with normal face recognition.

  2011influential citation
• The Literate Brain: The Relationship between Spelling and Reading

  2011cites this paper
• Disorders of higher visual processing.

  2011cites this paper
• DISORDERS OF COLOR AND OBJECT RECOGNITION: SYNDROMES OF THE VENTRAL OCCIPITOTEMPORAL PATHWAY

  2010cites this paper
• Visual and Semantic Processing of Living Things and Artifacts: An fMRI Study

  2010influential citation
• The orthography-specific functions of the left fusiform gyrus: evidence of modality and category specificity.

  2010cites this paper
• 錯綜図における形態知覚が保たれた連合型視覚失認の 1 例

  2010cites this paper
• Structural correlates of memory performance with diffusion tensor imaging

  2009cites this paper
• Visual Perceptual Consequences of Stroke

  2009cites this paper
• A Novel Experimental Method for Measuring Vergence and Accommodation Responses to the Main Near Visual Cues in Typical and Atypical Groups

  2009cites this paper
• The neuropsychological and neuroradiological correlates of slowly progressive visual agnosia

  2009cites this paper
• We're getting warmer—characterizing the mechanisms of face recognition with acquired prosopagnosia: A comment on Riddoch et al. (2008)

  2008cites this paper
• Vision and Higher Cortical Function

  2008cites this paper
• Chapter 21 Visual agnosia.

  2008cites this paper
• Face perception in its neurobiological and social context

  2008cites this paper
• The associative processes involved in faces-proper names versus animals-common names binding: a comparative ERP study.

  2007cites this paper
• Personhood and Neuroscience: Naturalizing or Nihilating?

  2007cites this paper
• Face familiarity feelings, the right temporal lobe and the possible underlying neural mechanisms.

  2007cites this paper
• GOLDSMITHS Research Online

  2007cites this paper
• A Mixture of Experts Model Exhibiting Prosopagnosia

  2006cites this paper
• Anatomical signatures of dyslexia in children: unique information from manual and voxel based morphometry brain measures.

  2005cites this paper
• Dynamics of Brain Activation During an Explicit Word and Image Recognition Task: An Electrophysiological Study

  2004cites this paper
• Prosopagnosia: ¿entidad única o múltiple?

  2004cites this paper
• From Segmentation to Imagination: Testing the Integrity of the Ventral Visual Processing Pathway in Alzheimer's Disease

  2004cites this paper
• [Prosopagnosia: is it a single or a multiple entity?].

  2004cites this paper
• Chapter 8 – Posterior Cerebral Artery Disease

  2004cites this paper
• TOPIC: SPECIFIC NEUROPSYCHOLOGICAL SYNDROMES

  2003cites this paper
• Visual object and face processing in mild-to-moderate Alzheimer's disease: from segmentation to imagination.

  2003cites this paper
• On the neural correlates of object recognition awareness: relationship to computational activities and activities mediating perceptual awareness.

  2002cites this paper
• Recognizing the un-real McCoy: Priming and the modularity of face recognition

  2002cites this paper
• Facial recognition and prosopagnosia: past and present concepts

  2001cites this paper
• On the correlation between synchronized oscillatory activities and consciousness.

  2001cites this paper
• Dynamics of brain activation during a word and image recognition task: An electrophysiological study

  2001cites this paper
• The influence of misnaming on object recognition: a case of multimodal agnosia.

  2001cites this paper
• Face module, face network: The cognitive architecture of the brain revealed through studies of face processing.

  2001cites this paper
• Face modules, face network: the cognitive architecture of the brain revealed through studies of face processing.

  2001cites this paper
• Left posterior BA37 is involved in object recognition: a TMS study.

  2001cites this paper
• The lateral occipital complex and its role in object recognition.

  2001cites this paper
• Annotation: the cognitive neuroscience of face recognition: implications for developmental disorders.

  2001cites this paper
• Superadditive effects of multiple lesions in a connectionist architecture: implications for the neuropsychology of optic aphasia.

  2000cites this paper
• EARLY COMMITMENT OF NEURAL SUBSTRATES FOR FACE RECOGNITION

  2000cites this paper
• Prosopagnosia in modular neural network models.

  1999cites this paper
• Neuroanatomic correlates of visual agnosia in Alzheimer’s disease

  1999cites this paper
• Imaging visual recognition: PET and fMRI studies of the functional anatomy of human visual recognition.

  1999cites this paper
• Neuroanatomy of Apraxia and Visual Agnosia in Alzheimer´s Disease

  1999cites this paper
• Organization of face and object recognition in modular neural network models

  1999cites this paper
• Chapter 10 Prosopagnosia in modular neural network models

  1999cites this paper
• Agnosie visuelle

  1999cites this paper
• Associative visual agnosia resulting from a disconnection between intact visual memory and semantic systems.

  1998cites this paper
• Alexia sin agrafia en el infarto cerebral occipital

  1998cites this paper
• Human visual object recognition: What have we learned from neuroimaging?

  1998cites this paper
• [Pure alexia: presentation of a case].

  1998cites this paper
• Specificity of face recognition: recognition of exemplars of non-face objects in prosopagnosia.

  1998cites this paper
• Associative agnosia and optic aphasia: qualitative or quantitative difference?

  1997cites this paper
• A Locus in Human Extrastriate Cortex for Visual Shape Analysis

  1997cites this paper
• PET imaging of maze processing.

  1997cites this paper
• What Is Special about Face Recognition? Nineteen Experiments on a Person with Visual Object Agnosia and Dyslexia but Normal Face Recognition

  1997cites this paper
• Postgeniculate afferent visual system and visual higher cortical function, 1994.

  1996cites this paper
• Is face recognition 'special'? Evidence from neuropsychology.

  1996cites this paper
• Knowledge, implicit knowledge and metaknowledge in visual agnosia and pure alexia.

  1995cites this paper
• What do we know about people with developmental prosopagnosia?

  year unknowncites this paper
• Human Neuroscience

  year unknowninfluential citation