Increased interleukin-6 production by murine bone marrow and bone cells after estrogen withdrawal.

No abstract is available for this paper.

• Publication year

  1993

• Venue

  Endocrinology

• Publication date

  1993-08-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1210/ENDO.133.2.8393776PMID 8393776
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Demonstration of estrogen and vitamin D receptors in bone marrow-derived stromal cells: up-regulation of the estrogen receptor by 1,25-dihydroxyvitamin-D3.

  1993cited by this paper
• Increased osteoclast development after estrogen loss: mediation by interleukin-6

  1992cited by this paper
• 17 beta-estradiol inhibits interleukin-6 production by bone marrow-derived stromal cells and osteoblasts in vitro: a potential mechanism for the antiosteoporotic effect of estrogens.

  1992cited by this paper
• Increased osteoclast development after estrogen loss: mediation by interleukin-6.

  1992cited by this paper
• Production of various cytokines by normal human osteoblast-like cells in response to interleukin-1 beta and tumor necrosis factor-alpha: lack of regulation by 17 beta-estradiol.

  1992cited by this paper
• Functional estrogen receptors in osteoblastic cells demonstrated by transfection with a reporter gene containing an estrogen response element.

  1991cited by this paper
• The effects of interleukin 6 and interleukin 3 on early hematopoietic events in long-term cultures of human marrow.

  1991cited by this paper
• Osteotropic factor responsiveness of highly purified populations of early and late precursors for human multinucleated cells expressing the osteoclast phenotype

  1991cited by this paper
• Chinese hamster ovarian cells transfected with the murine interleukin-6 gene cause hypercalcemia as well as cachexia, leukocytosis and thrombocytosis in tumor-bearing nude mice.

  1991cited by this paper
• IL-1 and tumor necrosis factor synergistically stimulate fibroblast IL-6 production and stabilize IL-6 messenger RNA.

  1990cited by this paper
• IL-6 is produced by osteoblasts and induces bone resorption.

  1990cited by this paper
• The bone marrow-derived stromal cell lines MC3T3-G2/PA6 and ST2 support osteoclast-like cell differentiation in cocultures with mouse spleen cells.

  1989cited by this paper
• Parathyroid hormone (PTH) and PTH-like protein (PLP) stimulate interleukin-6 production by osteogenic cells: a possible role of interleukin-6 in osteoclastogenesis.

  1989cited by this paper
• Interleukin‐6 is produced by bone and modulated by parathyroid hormone

  1989cited by this paper
• Evidence of estrogen receptors in normal human osteoblast-like cells.

  1988cited by this paper
• Osteoblastic cells are involved in osteoclast formation.

  1988cited by this paper
• Estrogen binding, receptor mRNA, and biologic response in osteoblast-like osteosarcoma cells.

  1988cited by this paper
• Osteoblastic cells mediate osteoclastic responsiveness to parathyroid hormone.

  1986cited by this paper
• Parathyroid hormone-stimulated development of osteoclasts in cultures of cells from neonatal murine calvaria.

  1986cited by this paper
• 1,25-Dihydroxycholecalciferol and glucocorticosteroid regulation of adenylate cyclase in an osteoblast-like cell line.

  1985cited by this paper
• A simplification of the protein assay method of Lowry et al. which is more generally applicable.

  1977cited by this paper

• Systemic immunological responses are dependent on sex and ovarian hormone presence following acute inhaled woodsmoke exposure

  2024cites this paper
• Raloxifene improves TNF-α-induced osteogenic differentiation inhibition of bone marrow mesenchymal stem cells and alleviates osteoporosis

  2020cites this paper
• Oestrogen-deficiency induces bone loss by modulating CD14+ monocyte and CD4+ T cell DR3 expression and serum TL1A levels

  2019cites this paper
• Bone and the Immune System

  2017cites this paper
• Animal Models in Bone Research

  2017cites this paper
• Bone Toxicology

  2017cites this paper
• Does systemic inflammation and immune activation contribute to fracture risk in HIV?

  2016influential citation
• The Effects of Hormonal Therapy and Exercise on Bone Turnover in Postmenopausal Women: A Randomised Double-Blind Pilot Study

  2016cites this paper
• Calcium supplements controversy in osteoporosis: a physiological mechanism supporting cardiovascular adverse effects

  2015cites this paper
• Ablation of p38α MAPK Signaling in Osteoblast Lineage Cells Protects Mice From Bone Loss Induced by Estrogen Deficiency.

  2015cites this paper
• THE EFFECTS OF COMMONLY USED DRUGS ON ORTHODONTIC TOOTH MOVEMENT : A SYSTEMATIC REVIEW

  2014cites this paper
• Circulating miR-21, miR-146a and Fas ligand respond to postmenopausal estrogen-based hormone replacement therapy--a study with monozygotic twin pairs.

  2014cites this paper
• Bone and Cytokines: Beyond IL-1, IL-6 and TNF-α

  2014cites this paper
• Replacement therapy with DHEA plus corticosteroids in patients with chronic inflammatory diseases - substitutes of adrenal and sex hormones

  2014cites this paper
• Estrogen Withdrawal from Osteoblasts and Osteocytes Causes Increased Mineralization and Apoptosis

  2014cites this paper
• Differential Roles of MAPK Kinases MKK3 and MKK6 in Osteoclastogenesis and Bone Loss

  2014cites this paper
• Vitamin K catabolite inhibition of ovariectomy-induced bone loss: structure-activity relationship considerations.

  2014cites this paper
• This is an electronic reprint of the original article. This reprint may differ from the original in pagination and typographic detail.

  2014cites this paper
• Regulation of the gp 80 and gp 130 Subunits of the IL-6 Receptor by Sex Steroids in the Murine Bone Marrow

  2013cites this paper
• Androgens and Skeletal Biology: Basic Mechanisms

  2013cites this paper
• Death receptor 3 : a regulator of bone turnover and new target for therapy for osteoporosis?

  2013cites this paper
• Seed, soil and secreted hormones: potential interactions of breast cancer cells with their endocrine/paracrine microenvironment and implications for treatment with bisphosphonates.

  2012cites this paper
• Adiposidad, estado pro-inflamatorio y resistencia a la insulina durante la menopausia.

  2012cites this paper
• Understanding the Aging Process Using Epidemiologic Approaches

  2012cites this paper
• Demystifying fatigue in Crohn’s disease:assessing prevalence, pathogenic and contributing factors for clinical application

  2012cites this paper
• HIV: Inflammation and Bone

  2012cites this paper
• Inflammatory markers in population studies of aging.

  2011cites this paper
• Oestrogen deficiency modulates particle-induced osteolysis

  2011cites this paper
• The association between microvascular and macrovascular endothelial function in patients with rheumatoid arthritis: a cross-sectional study

  2011cites this paper
• [Osteoblast-osteoclast interaction mechanisms].

  2011cites this paper
• Neuro-endocrine-immune Crosstalk and Implications for Cancer Therapy

  2011cites this paper
• modulates particle-induced osteolysis.

  2011cites this paper
• Decrease in particle‐induced osteolysis in ovariectomized mice

  2010cites this paper
• Glycitein decreases the generation of murine osteoclasts and increases apoptosis

  2010cites this paper
• Cytokines in the pathogenesis of osteoporosis

  2010cites this paper
• Androgen Action in Bone: Basic Cellular and Molecular Aspects

  2010cites this paper
• Bone remodeling, humoral networks and smart biomaterial technology for osteoporosis.

  2010influential citation
• The Molecular Biology of Sex Steroids in Bone: Similarities and Differences among the Sexes

  2010cites this paper
• Potential Role of Arginine, Glutamine and Taurine in Ameliorating Osteoporotic Biomarkers in Ovariectomized Rats

  2009cites this paper
• Protective action of aqueous black tea (Camellia sinensis) extract (BTE) against ovariectomy‐induced oxidative stress of mononuclear cells and its associated progression of bone loss

  2009cites this paper
• Sex Hormones and Immunosenescence

  2009cites this paper
• Osteoprotegerin and ligand of receptor activator of nuclear factor kappaB expression in ovariectomized rats during tooth movement.

  2009cites this paper
• Estrogens and Progestins

  2008cites this paper
• Preventive effects of genistein on leukocyte adhesion in femur venules and on bone-loss induced in ovariectomized female rats

  2008cites this paper
• arthritis and osteoporosis

  2008cites this paper
• Mechanisms of Estrogen Action in Bone

  2008cites this paper
• Estrogen and raloxifene in experimental arthritis and osteoporosis

  2008cites this paper
• Androgens Receptor Expression and Steroid Action in Bone

  2008cites this paper
• The "lively" cytokines network in beta-Thalassemia Major-related osteoporosis.

  2007cites this paper
• The “lively” cytokines network in β-Thalassemia Major-related osteoporosis

  2007cites this paper
• The complex role of estrogens in inflammation.

  2007cites this paper
• MONONUCLEAR CELLS ON HYPOGONADAL OSTEOPOROSIS: PREVENTION BY GARLIC

  2007cites this paper
• Role of peritoneal macrophages and lymphocytes in the development of hypogonadal osteoporosis in an ovariectomized rat model: possible phytoestrogenic efficacy of oil extract of garlic to preserve skeletal health

  2007cites this paper
• p38 MAPK Signaling in Oral-related Diseases

  2007cites this paper
• A novel femur window chamber for in vivo studies of bone microcirculation

  2007cites this paper
• Dietary arginine silicate inositol complex improves bone mineralization in quail.

  2006cites this paper
• Bone metabolism in ovariectomized rats with induced hyperthyroidism: the effect of estrogen replacement.

  2006cites this paper
• Assessment of mineralised bone mass and mineral supplementation in the newborn infant

  2006cites this paper
• Attenuation of osteoclastogenesis and osteoclast function by apigenin.

  2006cites this paper
• Effects of menopause and postmenopausal tibolone treatment on plasma TNFalpha, IL-4, IL-10, IL-12 cytokine pattern and some bone turnover markers.

  2006cites this paper
• Macrophage may responses to androgen via its receptor.

  2006cites this paper
• Enhanced Androgen Signaling with Androgen Receptor Overexpression in the Osteoblast Lineage Controls Skeletal Turnover, Matrix Quality, and Bone Architecture

  2005cites this paper
• Biochanin A stimulates osteoblastic differentiation and inhibits hydrogen peroxide-induced production of inflammatory mediators in MC3T3-E1 cells.

  2005cites this paper
• The Role of Hypogonadism in the Evolution of Bone Loss before and after Cardiac Transplantation

  2005cites this paper
• QSTEOGENESIS AND KAEMOPOEESXS : A SYMBIOTIC MICRQEMRONMENT

  2004cites this paper
• Mechanism of Action and Preclinical Profile of Raloxifene, a Selective Estrogen Receptor Modulator*

  2004cites this paper
• Pulsed electromagnetic field stimulation of bone marrow cells derived from ovariectomized rats affects osteoclast formation and local factor production

  2004cites this paper
• Energy balance and bone mineral density on male and female distance runners

  2004cites this paper
• Increased expression of IL-6 and RANK mRNA in human trabecular bone from fragility fracture of the femoral neck.

  2004cites this paper
• Changes in serum tumor necrosis factor (TNF-alpha) with kami-shoyo-san administration in depressed climacteric patients.

  2004cites this paper
• The skeleton : biochemical, genetic, and molecular interactions in development and homeostasis

  2004cites this paper
• Skeletal hormones and the C/EBP and Runx transcription factors: interactions that integrate and redefine gene expression.

  2004cites this paper
• The effects of alendronate and calcitonin on cytokines in postmenopausal osteoporosis: a 6-month randomized and controlled study.

  2003cites this paper
• Phytoestrogen genistein acts as an estrogen agonist on human osteoblastic cells through estrogen receptors alpha and beta.

  2003cites this paper
• Genetic regulation of osteoclast development and function

  2003cites this paper
• Genistein prevents bone resorption diseases by inhibiting bone resorption and stimulating bone formation.

  2003cites this paper
• Phytoestrogen genistein acts as an estrogen agonist on human osteoblastic cells through estrogen receptors α and β

  2003influential citation
• Avaliação de efeitos da prática de impostação de mãos sobre os sistemas hematológico e imunológico de camundongos machos

  2003cites this paper
• Androgen Action in Bone

  2003cites this paper
• Increased bone remodeling due to ovariectomy dramatically increases tumoral growth in the 5T2 multiple myeloma mouse model.

  2003cites this paper
• Effects of osteoporotic cytokines in ovary-intact and ovariectomised rats with induced hyperthyroidism; is skeletal responsiveness to thyroid hormone altered in estrogen deficiency?

  2003cites this paper
• Association between bone loss and promoter polymorphism in the IL-6 gene in elderly Japanese women with hip fracture

  2003cites this paper
• SP500263, a novel SERM, blocks osteoclastogenesis in a human bone cell model: role of IL-6 and GM-CSF.

  2003cites this paper
• Ethnic difference in contribution of alleles of the interleukin‐1 receptor antagonist gene to predisposition to osteoporosis

  2002cites this paper
• Is aging a disease? A review of the Serono Symposia Workshop held under the auspices of The 3rd World Congress on the Aging Male, February 9, 2002, Berlin, Germany

  2002cites this paper
• Differential Response of Estrogen Receptors (cid:1) and (cid:2) to SP500263, a Novel Potent Selective Estrogen Receptor Modulator

  2002cites this paper
• Changes in proinflammatory cytokine activity after menopause.

  2002cites this paper
• Chapter 43 – Androgens: Receptor Expression and Steroid Action in Bone

  2002cites this paper
• Effects of oestrogen deprivation on interleukin-6 production by peripheral blood mononuclear cells of postmenopausal women.

  2002cites this paper
• Differential response of estrogen receptors alpha and beta to SP500263, a novel potent selective estrogen receptor modulator.

  2002cites this paper
• Chapter 37 – Estrogens and Progestins

  2002cites this paper
• Possible pathogenetic role of new cytokines in postmenopausal osteoporosis and changes during calcitonin plus calcium therapy

  2002influential citation
• Animal Models in Osteoporosis Research

  2002cites this paper
• Expression of Interleukin-6 (IL-6) and IL-6 receptor mRNA in human bone samples from pre- and postmenopausal women.

  2002cites this paper
• Sex steroids and bone.

  2002cites this paper
• Chapter 39 – Mechanisms of Estrogen Action in Bone

  2002cites this paper
• Pathophysiologie der Osteoporose und therapeutische Konsequenzen

  2002cites this paper
• Interleukin-1β gene and receptor antagonist gene polymorphisms in patients with calcium oxalate stones

  2001cites this paper
• Estrogen receptor alpha, but not estrogen receptor beta, is involved in the regulation of the OPG/RANKL (osteoprotegerin/receptor activator of NF-kappa B ligand) ratio and serum interleukin-6 in male mice.

  2001cites this paper
• Regulation of Bone Cell Function by Estrogens

  2001cites this paper