Drug transporters in the lung--do they play a role in the biopharmaceutics of inhaled drugs?

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Journal of Pharmacy and Science

• Publication date

  2010-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/jps.21995PMID 19950388
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• RT‐PCR analysis of ABC, SLC and SLCO drug transporters in human lung epithelial cell models

  2009cited by this paper
• In‐vitro respiratory drug absorption models possess nominal functional P‐glycoprotein activity

  2009cited by this paper
• Identification of the Efflux Transporter of the Fluoroquinolone Antibiotic Ciprofloxacin in Murine Macrophages: Studies with Ciprofloxacin-Resistant Cells

  2009cited by this paper
• ABCG2: a perspective.

  2009cited by this paper
• Transport of Dicationic Drugs Pentamidine and Furamidine by Human Organic Cation Transporters

  2009cited by this paper
• P-Glycoprotein-Mediated Transport of Moxifloxacin in a Calu-3 Lung Epithelial Cell Model

  2009cited by this paper
• RT-PCR analysis of ABC, SLC and SLCO drug transporters in human lung epithelial cell models.

  2009cited by this paper
• Pulmonary elimination rate of inhaled 99mTc-sestamibi radioaerosol is delayed in healthy cigarette smokers.

  2008cited by this paper
• Lack of difference in pulmonary absorption of digoxin, a P‐glycoprotein substrate, in mdr1a‐deficient and mdr1a‐competent mice

  2008cited by this paper
• Xenobiotic transporters of the human organic anion transporting polypeptides (OATP) family

  2008cited by this paper
• Molecular and functional expression of multidrug resistance-associated protein-1 in primary cultured rat alveolar epithelial cells.

  2008cited by this paper
• Organic cation transporters

  2008cited by this paper
• Arachidonic acid pathway activates multidrug resistance related protein in cultured human lung cells

  2008cited by this paper
• The inhibitory effects of fluoroquinolones on L-carnitine transport in placental cell line BeWo.

  2008cited by this paper
• Chemotoxicity of doxorubicin and surface expression of P-glycoprotein (MDR1) is regulated by the Pseudomonas aeruginosa toxin Cif.

  2008cited by this paper
• The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADME-Tox).

  2008cited by this paper
• Effect of COPD treatments on MRP1-mediated transport in bronchial epithelial cells

  2008cited by this paper
• Pulmonary alveolar epithelial uptake of S-nitrosothiols is regulated by L-type amino acid transporter.

  2008cited by this paper
• In vitro cell culture models for the assessment of pulmonary drug disposition.

  2008cited by this paper
• Role of transport proteins in drug discovery and development: a pharmaceutical perspective

  2008cited by this paper
• hPEPT1 is responsible for uptake and transport of Gly-Sar in the human bronchial airway epithelial cell-line Calu-3

  2008cited by this paper
• Organic cation transporters and their pharmacokinetic and pharmacodynamic consequences.

  2008cited by this paper
• ABC multidrug transporters: structure, function and role in chemoresistance.

  2008cited by this paper
• Role of transport proteins in drug discovery and development: a pharmaceutical perspective.

  2008cited by this paper
• MRP class of human ATP binding cassette (ABC) transporters: historical background and new research directions

  2008cited by this paper
• The epithelial cholinergic system of the airways

  2008cited by this paper
• In vitro cell culture models for the assessment of pulmonary drug disposition

  2008cited by this paper
• Polyspecific Organic Cation Transporters: Structure, Function, Physiological Roles, and Biopharmaceutical Implications

  2007cited by this paper
• Air-liquid interface (ALI) culture of human bronchial epithelial cell monolayers as an in vitro model for airway drug transport studies.

  2007cited by this paper
• Down-regulation of the non-neuronal acetylcholine synthesis and release machinery in acute allergic airway inflammation of rat and mouse.

  2007cited by this paper
• Involvement of Breast Cancer Resistance Protein (ABCG2) in the Biliary Excretion Mechanism of Fluoroquinolones

  2007cited by this paper
• Decreased P‐glycoprotein (P‐gp/MDR1) expression in inflamed human intestinal epithelium is independent of PXR protein levels

  2007cited by this paper
• The effect of corticosteroids on the disposal of long-acting beta2-agonists by airway smooth muscle cells.

  2007cited by this paper
• Monolayers of porcine alveolar epithelial cells in primary culture as an in vitro model for drug absorption studies.

  2007cited by this paper
• OCTN2-mediated carnitine uptake in a newly discovered human proximal tubule cell line (Caki-1).

  2007cited by this paper
• Epithelial organic cation transporters ensure pH-dependent drug absorption in the airway.

  2007cited by this paper
• Cigarette smoke extract affects functional activity of MRP1 in bronchial epithelial cells

  2007cited by this paper
• P-glycoprotein (MDR1) functional activity in human alveolar epithelial cell monolayers

  2007cited by this paper
• New strategies to address drug-drug interactions involving OATPs.

  2007cited by this paper
• Localization of the ABCG2 mitoxantrone resistance-associated protein in normal tissues.

  2006cited by this paper
• Cellular functions of vaults and their involvement in multidrug resistance.

  2006cited by this paper
• Role of acetylcholine and polyspecific cation transporters in serotonin-induced bronchoconstriction in the mouse

  2006cited by this paper
• Single high dose dexamethasone treatment decreases the pathological score and increases the survival rate of paraquat-intoxicated rats.

  2006cited by this paper
• Organic anion transporter family: current knowledge.

  2006cited by this paper
• Culture of Calu-3 Cells at the Air Interface Provides a Representative Model of the Airway Epithelial Barrier

  2006cited by this paper
• Towards an in vitro model of cystic fibrosis small airway epithelium: characterisation of the human bronchial epithelial cell line CFBE41o-

  2006cited by this paper
• Modulation of p-glycoprotein and breast cancer resistance protein by some prescribed corticosteroids.

  2006cited by this paper
• Diminished expression of multidrug resistance-associated protein 1 (MRP1) in bronchial epithelium of COPD patients

  2006cited by this paper
• Tissue distribution and thyroid hormone regulation of Pept1 and Pept2 mRNA in rodents.

  2006cited by this paper
• Structure and function of the MRP2 (ABCC2) protein and its role in drug disposition

  2006cited by this paper
• Expression profiles of 50 xenobiotic transporter genes in humans and pre-clinical species: A resource for investigations into drug disposition

  2006cited by this paper
• Scientific perspectives on drug transporters and their role in drug interactions.

  2006cited by this paper
• Human respiratory epithelial cell culture for drug delivery applications.

  2005cited by this paper
• Expression of lung resistance-related protein, LRP, and multidrug resistance-related protein, MRP1, in normal human lung cells in long-term cultures

  2005cited by this paper
• Polyspecific cation transporters mediate luminal release of acetylcholine from bronchial epithelium.

  2005cited by this paper
• Evaluation of drug-drug interaction in the hepatobiliary and renal transport of drugs.

  2005cited by this paper
• Brain permeability of inhaled corticosteroids

  2005cited by this paper
• Monitoring the initial pulmonary absorption of two different beclomethasone dipropionate aerosols employing a human lung reperfusion model

  2005cited by this paper
• TISSUE DISTRIBUTION AND HEPATIC AND RENAL ONTOGENY OF THE MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN (MRP) FAMILY IN MICE

  2005cited by this paper
• P-glycoprotein expression increases ATP release in respiratory cystic fibrosis cells.

  2005cited by this paper
• Functional characterization of the peptide transporter PEPT2 in primary cultures of human upper airway epithelium.

  2005cited by this paper
• Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense.

  2005cited by this paper
• Role of organic anion transporting polypeptide 2 in pharmacokinetics of digoxin and beta-methyldigoxin in rats.

  2005cited by this paper
• Salbutamol is actively absorbed across human bronchial epithelial cell layers.

  2005cited by this paper
• Immuno-histochemical detection of MRPs in human lung cells in culture.

  2005cited by this paper
• Identification of Budesonide and Prednisone as Substrates of the Intestinal Drug Efflux Pump P-glycoprotein

  2004cited by this paper
• The proton oligopeptide cotransporter family SLC15 in physiology and pharmacology

  2004cited by this paper
• Molecular mechanisms of pulmonary peptidomimetic drug and peptide transport.

  2004cited by this paper
• Respiratory Research BioMed Central Review

  2004cited by this paper
• KINETIC CHARACTERIZATION OF P-GLYCOPROTEIN-MEDIATED EFFLUX OF RHODAMINE 6G IN THE INTACT RABBIT LUNG

  2004cited by this paper
• Identification and functional assessment of the novel murine organic anion transporter Oat5 (Slc22a19) expressed in kidney.

  2004cited by this paper
• Identification of the gonad-specific anion transporter SLCO6A1 as a cancer/testis (CT) antigen expressed in human lung cancer.

  2004cited by this paper
• N‐acetylcysteine enhances multidrug resistance‐associated protein 1 mediated doxorubicin resistance

  2004cited by this paper
• Genetic Variants of the Human H+/Dipeptide Transporter PEPT2: Analysis of Haplotype Functions

  2004cited by this paper
• The multispecific organic anion transporter family: properties and pharmacological significance.

  2004cited by this paper
• Profile of P-glycoprotein distribution in the rat and its possible influence on the salbutamol intestinal absorption process.

  2004cited by this paper
• The organic anion transporter (OATP) family.

  2004cited by this paper
• Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview.

  2003cited by this paper
• Constitutive Expression of P-Glycoprotein in Normal Lung Alveolar Epithelium and Functionality in Primary Alveolar Epithelial Cultures

  2003cited by this paper
• Identification and characterization of novel rat and human gonad-specific organic anion transporters.

  2003cited by this paper
• 16HBE14o- Human Bronchial Epithelial Cell Layers Express P-Glycoprotein, Lung Resistance-Related Protein, and Caveolin-1

  2003cited by this paper
• The human bronchial epithelial cell line 16HBE14o- as a model system of the airways for studying drug transport.

  2003cited by this paper
• Pharmacokinetics of idarubicin in the isolated perfused rat lung: effect of cinchonine and rutin

  2003cited by this paper
• Real-time reverse transcription-PCR expression profiling of the complete human ATP-binding cassette transporter superfamily in various tissues.

  2003cited by this paper
• Molecular characterization of human and rat organic anion transporter OATP-D.

  2003cited by this paper
• Drug Absorption from the Isolated Perfused Rat Lung–Correlations with Drug Physicochemical Properties and Epithelial Permeability

  2003cited by this paper
• Tissue distribution and chemical induction of multiple drug resistance genes in rats.

  2002cited by this paper
• Transport of HIV-Protease Inhibitors Across 1α,25di-Hydroxy Vitamin D3-Treated Calu-3 Cell Monolayers: Modulation of P-Glycoprotein Activity

  2002cited by this paper
• Organ distribution of multidrug resistance proteins 1, 2, and 3 (Mrp1, 2, and 3) mRNA and hepatic induction of Mrp3 by constitutive androstane receptor activators in rats.

  2002cited by this paper
• Distribution and function of the peptide transporter PEPT2 in normal and cystic fibrosis human lung

  2002cited by this paper
• Transport and Utilization of Arginine and Arginine-Containing Peptides by Rat Alveolar Macrophages

  2002cited by this paper
• Expression of multidrug resistance‐associated protein 2 (MRP2) in normal human tissues and carcinomas using tissue microarrays

  2002cited by this paper
• Peptide transport in the mammary gland: expression and distribution of PEPT2 mRNA and protein.

  2002cited by this paper
• Isolation, characterization and differential gene expression of multispecific organic anion transporter 2 in mice.

  2002cited by this paper
• Multidrug resistance related molecules in human and murine lung.

  2002cited by this paper
• Identification of a novel human organic anion transporting polypeptide as a high affinity thyroxine transporter.

  2002cited by this paper
• Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver.

  2001cited by this paper
• Multidrug resistance-associated protein-1 functional activity in Calu-3 cells.

  2001cited by this paper
• P-glycoprotein efflux pump expression and activity in Calu-3 cells.

  2001cited by this paper
• Localization of the peptide transporter PEPT2 in the lung: implications for pulmonary oligopeptide uptake.

  2001cited by this paper

• Mapping the ABC Transporter Landscape in the Human Lung: A Comprehensive Characterisation of P-gp, MRP1 and BCRP Expression and Functional Activity in Human Lung Epithelial Cells.

  2025cites this paper
• Population pharmacokinetics study on nebulized and intravenous administration of polymyxin B in patients with pneumonia caused by multidrug-resistant gram-negative bacteria

  2025cites this paper
• Optimizing the pharmacokinetics and selectivity of TMPRSS2 inhibitors.

  2025cites this paper
• Is Rifampin (Rifampicin) Essential for the Treatment of Rhodococcus equi Infections in Foals? A Critical Review of the Role of Rifampin

  2025cites this paper
• Assessment of drug permeability using a small airway microphysiological system

  2025cites this paper
• Modeling lung transporters and their influence on inhaled drug disposition.

  2025cites this paper
• Insights into Inhalation Drug Disposition: The Roles of Pulmonary Drug-Metabolizing Enzymes and Transporters

  2024cites this paper
• A 3D Model of the Human Lung Airway for Evaluating Permeability of Inhaled Drugs.

  2024cites this paper
• Soluplus–TPGS Mixed Micelles as a Delivery System for Brigatinib: Characterization and In Vitro Evaluation

  2024cites this paper
• Pulmonary drug delivery devices and nanosystems as potential treatment strategies for acute respiratory distress syndrome (ARDS).

  2024cites this paper
• Emerging roles of ncRNAs regulating ABCC1 on chemotherapy resistance of cancer – a review

  2023cites this paper
• Lung penetration and pneumococcal target binding of antibiotics in lower respiratory tract infection

  2022cites this paper
• Impact of P-gp and BCRP on pulmonary drug disposition assessed by PET imaging in rats.

  2022cites this paper
• Predicting Regional Respiratory Tissue and Systemic Concentrations of Orally Inhaled Drugs through a Novel PBPK Model

  2022cites this paper
• Fundamentals and Applications of Isolated Perfused Lung (IPL) Model in the Development of Pulmonary Drug Delivery.

  2022cites this paper
• Expression and Function of ABC Transporters in Human Alveolar Epithelial Cells

  2022cites this paper
• Pharmacokinetic considerations to optimize clinical outcomes for COVID-19 drugs

  2022cites this paper
• Airway local endoscopic pharmacological treatment; current applications and future concepts.

  2022cites this paper
• Influence of Particle Size and Particle Deposition of Inhaled Medication in Lung Disease: A Comrehensive Review

  2022cites this paper
• PET imaging to assess the impact of P-glycoprotein on pulmonary drug delivery in rats.

  2021cites this paper
• Modification of Apremilast from Pills to Aerosol a Future Concept

  2021cites this paper
• Organic cation transporters (OCTs/OCTNs) in human primary alveolar epithelial cells.

  2021cites this paper
• Epithelial permeability and drug absorption in the lungs

  2021cites this paper
• Drug distribution in lung tissue

  2021cites this paper
• Pulmonary Drug Delivery

  2021cites this paper
• Aerosol-based Pulmonary Delivery of Therapeutic Molecules from Food Sources: Delivery Mechanism, Research Trends, and the Way Forward

  2021cites this paper
• The Effect of Modified Porcine Surfactant Alone or in Combination with Polymyxin B on Lung Homeostasis in LPS-Challenged and Mechanically Ventilated Adult Rats

  2020cites this paper
• Organic Cation Transporters in the Lung—Current and Emerging (Patho)Physiological and Pharmacological Concepts

  2020cites this paper
• Disruption of small molecule transporter systems by Transporter‐Interfering Chemicals (TICs)

  2020cites this paper
• The potential of Atorvastatin for chronic lung diseases therapy

  2020cites this paper
• Cigarette smoke extract combined with lipopolysaccharide reduces OCTN1/2 expression in human alveolar epithelial cells in vitro and rat lung in vivo under inflammatory conditions.

  2020cites this paper
• In vitro, ex vivo and in vivo methods of lung absorption for inhaled drugs.

  2020cites this paper
• Organic Cation Transporters (OCTs) in EpiAirway™, a Cellular Model of Normal Human Bronchial Epithelium

  2020cites this paper
• Towards a Quantitative Mechanistic Understanding of Localized Pulmonary Tissue Retention—A Combined In Vivo/In Silico Approach Based on Four Model Drugs

  2020cites this paper
• Characterization of ABC Transporters in EpiAirway™, a Cellular Model of Normal Human Bronchial Epithelium

  2020cites this paper
• Regional differences in airway susceptibility to cigarette smoke: An investigational case study of epithelial function and gene alterations in in vitro airway epithelial three-dimensional cultures

  2020cites this paper
• Strategies for pulmonary delivery of drugs

  2020cites this paper
• Drug Metabolism and Pharmacogenetics

  2019cites this paper
• Functional analysis of OCTN2 and ATB0,+ in normal human airway epithelial cells

  2019cites this paper
• Rational particle design to overcome pulmonary barriers for obstructive lung diseases therapy.

  2019cites this paper
• Membrane transporter data to support kinetically-informed chemical risk assessment using non-animal methods: Scientific and regulatory perspectives

  2019cites this paper
• Induction of multidrug resistance-associated protein 3 expression by diesel exhaust particle extract in human bronchial epithelial BEAS-2B cells.

  2019cites this paper
• Pharmacokinetic/pharmacodynamic relationship of pulmonary administration methods for milrinone : a translational approach

  2018cites this paper
• Quantification of membrane transporter proteins in human lung and immortalized cell lines using targeted quantitative proteomic analysis by isotope dilution nanoLC–MS/MS

  2018cites this paper
• A Genome-Wide Linkage Study for Chronic Obstructive Pulmonary Disease in a Dutch Genetic Isolate Identifies Novel Rare Candidate Variants

  2018cites this paper
• Nrf2 overexpression protects against paraquat-induced A549 cell injury primarily by upregulating P-glycoprotein and reducing intracellular paraquat accumulation

  2018cites this paper
• Repurposing of statins via inhalation to treat lung inflammatory conditions

  2018cites this paper
• Evaluating drug delivery to the lung using polyamine ion-pairs

  2018cites this paper
• Expression analysis of human solute carrier (SLC) family transporters in nasal mucosa and RPMI 2650 cells

  2018cites this paper
• Expression of MATE1, P-gp, OCTN1 and OCTN2, in epithelial and immune cells in the lung of COPD and healthy individuals

  2018cites this paper
• Ion-Pairing with Spermine Targets Theophylline To the Lungs via the Polyamine Transport System.

  2018cites this paper
• Encapsulation of desmopressin into hydrophobic nanoparticles and hydrophilic microparticles for pulmonary drug delivery

  2017cites this paper
• Études biopharmaceutiques et formulation de chloramphénicol et de thiamphénicol pour le traitement ciblé des infections pulmonaires par voie inhalée

  2017cites this paper
• Activity of Multidrug Resistance-Associated Proteins 1-5 (MRP1-5) in the RPMI 2650 Cell Line and Explants of Human Nasal Turbinate.

  2017cites this paper
• Current Progress Toward a Better Understanding of Drug Disposition Within the Lungs: Summary Proceedings of the First Workshop on Drug Transporters in the Lungs.

  2017cites this paper
• Aerosolized Polymyxin B for Treatment of Respiratory Tract Infections: Determination of Pharmacokinetic-Pharmacodynamic Indices for Aerosolized Polymyxin B against Pseudomonas aeruginosa in a Mouse Lung Infection Model

  2017cites this paper
• Elucidating the Pharmacokinetics/Pharmacodynamics of Aerosolized Colistin against Multidrug-Resistant Acinetobacter baumannii and Klebsiella pneumoniae in a Mouse Lung Infection Model

  2017cites this paper
• Enhanced expression of Organic Cation Transporters in bronchial epithelial cell layers following insults associated with asthma – Impact on salbutamol transport

  2017cites this paper
• Is RPMI 2650 a Suitable In Vitro Nasal Model for Drug Transport Studies?

  2017cites this paper
• SLC and ABC Transporters: Expression, Localization, and Species Differences at the Blood-Brain and the Blood-Cerebrospinal Fluid Barriers

  2017cites this paper
• Functional and molecular analysis of Organic Cation Transporters (OCTs and OCTNs) in human airway epithelial cells and macrophages

  2017cites this paper
• The Differential Absorption of a Series of P-Glycoprotein Substrates in Isolated Perfused Lungs from Mdr1a/1b Genetic Knockout Mice can be Attributed to Distinct Physico-Chemical Properties: an Insight into Predicting Transporter-Mediated, Pulmonary Specific Disposition

  2017cites this paper
• Development of a Novel Quantitative Structure-Activity Relationship Model to Accurately Predict Pulmonary Absorption and Replace Routine Use of the Isolated Perfused Respiring Rat Lung Model

  2016cites this paper
• Pharmacokinetics/Pharmacodynamics of Pulmonary Delivery of Colistin against Pseudomonas aeruginosa in a Mouse Lung Infection Model

  2016influential citation
• Penetration of antimicrobials to pulmonary epithelial lining fluid and muscle and impact of drug physicochemical properties determined by microdialysis.

  2016cites this paper
• Inhaled Biologics: From Preclinical to Product Approval.

  2016cites this paper
• Pharmacokinetic Considerations of Inhaled Pharmaceuticals for Systemic Delivery.

  2016cites this paper
• Transport mechanisms at the pulmonary mucosa: implications for drug delivery

  2016cites this paper
• Lung-targeted receptor occupancy by drug inhalation : an experimental and computational evaluation.

  2016cites this paper
• Organic cation rhodamines for screening organic cation transporters in early stages of drug development.

  2016cites this paper
• Alteration in Intrapulmonary Pharmacokinetics of Aerosolized Model Compounds Due to Disruption of the Alveolar Epithelial Barriers Following Bleomycin-Induced Pulmonary Fibrosis in Rats.

  2016cites this paper
• Development of a Multicompartment Permeability-Limited Lung PBPK Model and Its Application in Predicting Pulmonary Pharmacokinetics of Antituberculosis Drugs

  2015cites this paper
• Drug Transporter Protein Quantification of Immortalized Human Lung Cell Lines Derived from Tracheobronchial Epithelial Cells (Calu-3 and BEAS2-B), Bronchiolar-Alveolar Cells (NCI-H292 and NCI-H441), and Alveolar Type II-like Cells (A549) by Liquid Chromatography-Tandem Mass Spectrometry.

  2015cites this paper
• Interplay of Breast Cancer Resistance Protein (BCRP) and Metabolizing Enzymes.

  2015cites this paper
• Chapter 2 Pulmonary Drug Metabolism , Clearance , and Absorption

  2015cites this paper
• Specific expression of OATPs in primary small cell lung cancer (SCLC) cells as novel biomarkers for diagnosis and therapy.

  2015influential citation
• Functional characterization of the organic cation transporters (OCTs) in human airway pulmonary epithelial cells.

  2015cites this paper
• Regulation of Human Hepatic Drug Transporter Activity and Expression by Diesel Exhaust Particle Extract

  2015cites this paper
• Role of integrin-linked kinase in drug resistance of lung cancer

  2015cites this paper
• In Vitro Testing for Orally Inhaled Products: Developments in Science-Based Regulatory Approaches

  2015cites this paper
• Permeation of Therapeutic Drugs in Different Formulations across the Airway Epithelium In Vitro

  2015cites this paper
• The Characterization of the Human Nasal Epithelial Cell Line RPMI 2650 Under Different Culture Conditions and Their Optimization for an Appropriate in vitro Nasal Model

  2015cites this paper
• Wide expression of type I Na+-phosphate cotransporter 3 (NPT3/SLC17A2), a membrane potential-driven organic anion transporter.

  2015cites this paper
• Absorption of ipratropium and l-carnitine into the pulmonary circulation of the ex-vivo rat lung is driven by passive processes rather than active uptake by OCT/OCTN transporters.

  2015cites this paper
• The characterization of the human cell line Calu-3 under different culture conditions and its use as an optimized in vitro model to investigate bronchial epithelial function.

  2015cites this paper
• “Target-Site” Drug Metabolism and Transport

  2015influential citation
• Protein kinase C affects the internalization and recycling of organic anion transporting polypeptide 1B1.

  2015cites this paper
• Intrabronchial Microdialysis: Effects of Probe Localization on Tissue Trauma and Drug Penetration into the Pulmonary Epithelial Lining Fluid

  2015cites this paper
• Lung Anatomy and Physiology and Their Implications for Pulmonary Drug Delivery

  2015cites this paper
• Examining the selectivity in the impact of pulmonary P-gp upon the absorption of its substrates using an IPML model with knockout mice

  2015cites this paper
• Expression and function of multidrug resistance-related protein 1 in human lung epithelial cells

  2014influential citation
• Critical domains within the sequence of human organic anion transporting polypeptides.

  2014cites this paper
• Pharmaceutical Aerosols and Pulmonary Drug Delivery

  2014cites this paper
• Delivery strategies for sustained drug release in the lungs.

  2014cites this paper
• Biopharmaceutical Characterization of Nebulized Antimicrobial Agents in Rats: 1. Ciprofloxacin, Moxifloxacin, and Grepafloxacin

  2014cites this paper
• Across the pulmonary epithelial barrier: Integration of physicochemical properties and human cell models to study pulmonary drug formulations.

  2014cites this paper
• Experimentation with aerosol bonsetan, pirfenidone, treprostinil and sidenafil.

  2014cites this paper
• In vitro and ex vivo methods predict the enhanced lung residence time of liposomal ciprofloxacin formulations for nebulisation.

  2014cites this paper
• Biopharmaceutical Characterization of Nebulized Antimicrobial Agents in Rats: 2. Colistin

  2014cites this paper
• Defense mechanisms of the respiratory system and aerosol production systems.

  2014cites this paper