The Coronary Drug Project. Initial findings leading to modifications of its research protocol.

No abstract is available for this paper.

• Publication year

  1970

• Venue

  Journal of the American Medical Association (JAMA)

• Publication date

  Unknown publication date

• Fields of study

  Medicine

• Identifiers
  DOI 10.1001/jama.214.7.1303PMID 4320008
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• No references are available for this paper.

• Feminizing Hormone Therapy in the Male Spontaneous Hypertensive Rat Impairs Accuracy of Estimated Renal Filtration.

  2025cites this paper
• Estrogen Influences Human Microvascular Endothelial Function Via Sex-Specific Regulation of Sphingolipids

  2025cites this paper
• Re-evaluation of the traditional diet-heart hypothesis: analysis of recovered data from Minnesota Coronary Experiment (1968-73)

  2024cites this paper
• Cross-Sex Hormone Therapy Is Associated With Loss of Circadian Rhythm in the Male Rat

  2024cites this paper
• Evidence-based pharmacotherapy in cardiology. National guideline

  2024cites this paper
• Cardiovascular disease and feminizing gender-affirming hormone therapy: Implications for the provision of safe and lifesaving care.

  2023cites this paper
• Ethics Committees: Structure, Roles, and Issues

  2023cites this paper
• International society of sports nutrition position stand: nutritional concerns of the female athlete

  2023cites this paper
• Estrogen and the Vascular Endothelium: The Unanswered Questions.

  2023cites this paper
• Atherosclerotic Cardiovascular Disease in Women: Providing Protection With Lipid-Altering Agents.

  2023cites this paper
• Linking Cardiovascular Risk With Estradiol Level in Men.

  2023cites this paper
• The Use of Female Menopausal Hormonal Replacement Therapy To Prevent Cardiovascular Disease in Women and in Men: A Lack of Clinical Benefit and the Potential for Harm.

  2023cites this paper
• Sex hormones, adiposity, and metabolic traits in men and women: a Mendelian randomisation study

  2022cites this paper
• Medical Transition for Gender Diverse Patients

  2020cites this paper
• Type 2 diabetes-related sex differences in cardiovascular risk: reasons, ramifications, and clinical realities.

  2019cites this paper
• Hormonale Therapiemöglichkeiten beim Mann in der "Andropause"

  2019cites this paper
• Cardiovascular implications of gender-affirming hormone treatment in the transgender population.

  2019cites this paper
• Conditional power as an aid in making interim decisions in observational studies

  2018cites this paper
• Improved adherence adjustment in the Coronary Drug Project

  2018cites this paper
• Molecular Risk Factors of Pulmonary Arterial Hypertension

  2017cites this paper
• The effects of oestrogens and their receptors on cardiometabolic health

  2017cites this paper
• Prevention of acute ischemic heart disease by using estrogenic metabolites

  2017cites this paper
• Associations of Endogenous Estradiol and Testosterone Levels With Plaque Composition and Risk of Stroke in Subjects With Carotid Atherosclerosis

  2017cites this paper
• Gender, Estrogen, and Obliterative Lesions in the Lung

  2017cites this paper
• Niacin for primary and secondary prevention of cardiovascular events.

  2017cites this paper
• Trials of testosterone replacement reporting cardiovascular adverse events

  2017cites this paper
• TASK FORCES Task Force 1. Pathogenesis of Coronary Disease: The Biologic Role of Risk Factors

  2016cites this paper
• Adherence adjustment in the Coronary Drug Project: A call for better per-protocol effect estimates in randomized trials

  2016cites this paper
• All cholesterol-lowering interventions are expected to reduce stroke: Confirmatory data from IMPROVE-IT

  2016cites this paper
• The Success Story of LDL Cholesterol Lowering.

  2016cites this paper
• Jerome Cornfield’s Bayesian approach to assessing interim results in clinical trials

  2016cites this paper
• Re-evaluation of the traditional diet-heart hypothesis: analysis of recovered data from Minnesota Coronary Experiment (1968-73)

  2016cites this paper
• The Success Story of LDL Cholesterol Lowering

  2016cites this paper
• Management of Hypogonadism in Cardiovascular Patients: What Are the Implications of Testosterone Therapy on Cardiovascular Morbidity?

  2016cites this paper
• ANDROGENS AND CORONARY ARTERY DISEASE

  2015cites this paper
• The Role of Testosterone Therapy in Cardiovascular Mortality: Culprit or Innocent Bystander?

  2015cites this paper
• Increased Risk of Non-Fatal Myocardial Infarction Following Testosterone Therapy Prescription in Men

  2014cites this paper
• Is men's health just a single letter?

  2014cites this paper
• Estradiol concentrations in young healthy US versus Chinese men

  2014cites this paper
• Risk factors associated with cardiovascular events during testosterone administration in older men with mobility limitation.

  2013cites this paper
• Lipid Lowering Drugs and Hyperlipidaemia

  2012cites this paper
• Postmenopausal Hormone Replacement Therapy, Coronary Heart Disease and Plasma Lipoproteins

  2012cites this paper
• Current development in clinical trials: issues old and new

  2012cites this paper
• Regulation of physiological and metabolic function of muscle by female sex steroids.

  2012cites this paper
• Jerome Cornfield's contributions to early large randomized clinical trials and some reminiscences from the years of the slippery doorknobs

  2012cites this paper
• Estrogens and atherosclerosis: insights from animal models and cell systems.

  2012cites this paper
• Testosterone, Hemostasis, and Cardiovascular Diseases in Men

  2011cites this paper
• Postmenopausal hormone therapy and cardiovascular disease in women.

  2010cites this paper
• Gene expression profile of endothelial cells exposed to estrogenic environmental compounds: implications to pulmonary vascular lesions.

  2010cites this paper
• Secondary prevention of ischaemic cardiac events.

  2009cites this paper
• Effects of gender and gonadectomy on growth and plasma cholesterol levels in pigs

  2009cites this paper
• Knowledge and Attitudes of Physicians about Lipids cardiovascular disease, family medicine, hypercholesterolemia, lipids, low-density lipoproteins

  2008cites this paper
• Estrogen-induced redox sensitive Id3 signaling controls the growth of vascular cells.

  2008cites this paper
• Considerations relevant to a rational transition from the present system to automated ECG analysis

  2007cites this paper
• Low serum testosterone and high serum estradiol associate with lower extremity peripheral arterial disease in elderly men. The MrOS Study in Sweden.

  2007cites this paper
• The pill and the pendulum.

  2007cites this paper
• VI. Importance of the electrocardiogram in populations outside the hospital

  2007cites this paper
• Postmenopausal Hormone Replacement Therapy: Endometrial and Breast Effects

  2007cites this paper
• Implications of Recent Clinical Trials of Postmenopausal Hormone Therapy for Management of Cardiovascular Disease

  2006cites this paper
• Artery Intima-Media Thickness in Middle-Aged Men Circulating Estradiol Is an Independent Predictor of Progression of Carotid

  2006cites this paper
• Endogenous Estradiol and Testosterone may Predispose toward Atherogenic Lipid Profile, but Higher Blood Level of Testosterone is Associated with Lower Number of Stenoses in the Coronary Arteries of Men with Coronary Disease

  2006cites this paper
• Effects of estrogens and progestins on high density lipoproteins

  2006cites this paper
• Cardiovascular risk and hormone replacement therapy

  2006cites this paper
• Coronary Intervention Study

  2005cites this paper
• An interdisciplinary analysis of the hormone replacement therapy saga

  2005cites this paper
• Hormone replacement therapy, cancer, controversies, and women’s health: historical, epidemiological, biological, clinical, and advocacy perspectives

  2005cites this paper
• Diethyistilbestrol Selectively Modulates Plasma Coagulation Protein Synthesis by the Perfused Rat Liver

  2005cites this paper
• Coronary Heart Disease

  2004cites this paper
• Commentary: hormone replacement therapy and coronary heart disease: four lessons.

  2004cites this paper
• Endogenous sex hormones and cardiovascular disease in men.

  2003cites this paper
• Cardiovascular effects of testosterone: implications of the “male menopause”?

  2003cites this paper
• Hormone replacement therapy and risk of cardiovascular disease: implications of the results of the Women's Health Initiative.

  2003cites this paper
• Grobbee Endogenous Sex Hormones and Cardiovascular Disease in Men Society

  2003cites this paper
• [Does hormone replacement therapy in menopause have a cardiovascular benefit?].

  2003cites this paper
• Prostate cancer

  2002cites this paper
• Hormones and the health of women: past, present, and future Keynote address *

  2002cites this paper
• Hormone replacement therapy: a time for pause.

  2002cites this paper
• Cardioprotective Benefits of Hormone Replacement Therapy

  2001cites this paper
• Estrogen-Progestin Hormone Replacement Therapy: Evaluation of Epidemiological Studies

  2001cites this paper
• Hormone replacement therapy, prothrombotic mutations, and the risk of incident nonfatal myocardial infarction in postmenopausal women.

  2001cites this paper
• Does tamoxifen enhance endothelial function by lowering the plasma levels of homocysteine?

  2001cites this paper
• Testosterone inhibits early atherogenesis by conversion to estradiol: Critical role of aromatase

  2001cites this paper
• Sex-related differences in the regulation of macrophage cholesterol metabolism

  2001cites this paper
• Initiation of hormone replacement therapy after acute myocardial infarction is associated with more cardiac events during follow-up.

  2001cites this paper
• CME Paper: Hormone Replacement Therapy for Prevention or Treatment of Atherosclerosis in Postmenopausal Women: Promises, Controversies, and Clinical Trials.

  2000cites this paper
• Hormone Replacement Therapy Should Not Be Used as Secondary Prevention of Coronary Heart Disease

  2000cites this paper
• Postmenopausal hormone replacement therapy increases coagulation activity and fibrinolysis.

  2000cites this paper
• Long-Term Cardiovascular Effects of High “Osteoprotective” Dose Levels of 17β-Estradiol in Spontaneously Hypertensive Rats

  2000cites this paper
• Divergent effects of hormone therapy on serum markers of inflammation in postmenopausal women with coronary artery disease on appropriate medical management.

  2000cites this paper
• The Heart and Estrogen/Progestin Replacement Study (HERS) in perspective – Results not very surprising

  2000cites this paper
• Gender representation in trials.

  2000cites this paper
• Effects of Hormone Replacement Therapy on Coagulation, Fibrinolysis, and Thrombosis Risk in Postmenopausal Women

  1999cites this paper
• Systematic review on the risk and benefit of different cholesterol-lowering interventions.

  1999cites this paper
• Postmenopausal hormone therapy, SERMs, and coronary heart disease in women

  1999cites this paper
• Assessment of the Risk for Venous Thromboembolism Among Users of Hormone Replacement Therapy

  1999cites this paper
• Sex steroids, insulin, and arterial stiffness in women and Men.

  1999cites this paper
• Report of a National Institutes of Health--Centers for Disease Control and Prevention workshop on the feasibility of conducting a randomized clinical trial to estimate the long-term health effects of intentional weight loss in obese persons.

  1999cites this paper
• Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research Group.

  1998cites this paper
• Hormone replacement therapy, heart disease, and other considerations.

  1998cites this paper
• Gender gap in aortic cholesterol accumulation in cholesterol-clamped rabbits: role of the endothelium and mononuclear-endothelial cell interaction.

  1998cites this paper