Recent developments of transition-state analogue glycosidase inhibitors of non-natural product origin.

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Chemical Reviews

• Publication date

  2002-01-29

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1021/CR000433KPMID 11841253
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Beta-D-glycosylamidines: potent, selective, and easily accessible 1-glycosidase inhibitors.

  2001cited by this paper
• Synthesis of 5-azacastanospermine, a conformationally restricted azafagomine analogue.

  2001cited by this paper
• A Free-Energy Relationship between the Rate of Acidic Hydrolysis of Glycosides and the pKa of Isofagomines

  2001cited by this paper
• A new class of glycosidase inhibitor: synthesis of salacinol and its stereoisomers.

  2001cited by this paper
• Isogalactofagomine lactam. A neutral nanomolar galactosidase inhibitor

  2001cited by this paper
• Glycogen phosphorylase inhibitors for treatment of type 2 diabetes mellitus

  2001cited by this paper
• Selective fowler reductions: asymmetric total syntheses of isofagomine and other 1-azasugars from methyl nicotinate.

  2001cited by this paper
• A new structural motif for the design of potent glucosidase inhibitors.

  2001cited by this paper
• Glycosidase inhibitors of gem-diamine 1-N-iminosugars. structures in media of enzyme assays.

  2001cited by this paper
• Noeuromycin, a glycosyl cation mimic that strongly inhibits glycosidases.

  2001cited by this paper
• Amino(hydroxymethyl)cyclopentanetriols, an Emerging Class of Potent Glycosidase Inhibitors—Part I: Synthesis and Evaluation of β‐D‐Pyranoside Analogues in the manno, gluco, galacto, and GlcNAc Series

  2001cited by this paper
• Stereoisomeric Imidazolo‐Pentoses − Synthesis, Chiroptical Properties, and Evaluation as Glycosidase Inhibitors

  2001cited by this paper
• β-d-Glycosylamidines: potent, selective, and easily accessible β-glycosidase inhibitors

  2001cited by this paper
• The rational design of an iminosugar inhibitor able to mimic substrate distortion occurring during retaining-cellulase hydrolysis

  2001cited by this paper
• Efficient synthesis of isofagomine and noeuromycin.

  2001cited by this paper
• Iminosugars: potential inhibitors of liver glycogen phosphorylase.

  2001cited by this paper
• Slow inhibition of almond beta-glucosidase by azasugars: determination of activation energies for slow binding.

  2001cited by this paper
• 1‐Azafagomine: A Hydroxyhexahydropyridazine That Potently Inhibits Enzymatic Glycoside Cleavage

  2001cited by this paper
• Amino(hydroxymethyl)cyclopentanetriols, an Emerging Class of Potent Glycosidase Inhibitors—Part II: Synthesis, Evaluation, and Optimization of β‐D‐Galactopyranoside Analogues

  2001cited by this paper
• Synthesis of 1-azagalactofagomine, a potent galactosidase inhibitor

  2001cited by this paper
• Glycosidase inhibition by cyclic sulfonium compounds.

  2001cited by this paper
• Synthesis of an 1′-Azasugar Analogue of Maltose

  2001cited by this paper
• A Large Difference in the Thermodynamics of Binding of Isofagomine and 1-Deoxynojirimycin to β-Glucosidase

  2000cited by this paper
• Chemoenzymatic synthesis of isogalactofagomine.

  2000cited by this paper
• Glycosidase inhibitors and their chemotherapeutic value, Part 2.

  2000cited by this paper
• β-Glycosidase inhibitors mimicking the pyranoside boat conformation

  2000cited by this paper
• Flexible synthesis and biological activity of uronic acid-type gem-diamine 1-N-iminosugars: a new family of glycosidase inhibitors.

  2000cited by this paper
• Nanomolar versus Millimolar Inhibition by Xylobiose-Derived Azasugars: Significant Differences between Two Structurally Distinct Xylanases

  2000cited by this paper
• Very Strong Inhibition of Glucosidases by C(2)-Substituted Tetrahydroimidazopyridines

  2000cited by this paper
• Synthesis of 3-substituted isofagomine analogues using an unusual syn hydrogenation reaction

  2000cited by this paper
• The Role of Sugar Substituents in Glycoside Hydrolysis

  2000cited by this paper
• Synthesis of 3-C-hydroxymethyl- and 3-deoxyisofagomine and investigation of their binding to β-glucosidase

  2000cited by this paper
• Processing Glucosidase Inhibition by 1-Azafagomine

  2000cited by this paper
• Synthesis of 2-substituted polyhydroxytetrahydropyrimidines (N-hydroxy cyclic guanidino-sugars): transition-state mimics of enzymatic glycosidic cleavage.

  2000cited by this paper
• The Inhibition of Bovine Kidney Hexosaminidase by N-Acetylglucosamine-Related 1,2,3- and 1,2,4-Triazoles Is in Agreement with an `anti'-Protonation

  2000cited by this paper
• Direct NMR‐Spectroscopic Determination of Active‐Enzyme Concentration by Titration with a Labeled Inhibitor: Determination of the kcat Value of Almond β‐Glucosidase

  2000cited by this paper
• A Comparison of Glucose- and Glucosamine-Related Inhibitors: Probing the Interaction of the 2-Hydroxy Group with Retaining beta-Glucosidases

  2000cited by this paper
• Enantiospecific synthesis of 1-azafagomine.

  2000cited by this paper
• A New, Simple, High-Affinity Glycosidase Inhibitor: Analysis of Binding through X-ray Crystallography, Mutagenesis, and Kinetic Analysis

  2000cited by this paper
• Stereoselective inhibition of alpha-L-fucosidases by N-benzyl aminocyclopentitols.

  2000cited by this paper
• Synthesis of (±)-isofagomine and its stereoisomers from arecoline

  2000cited by this paper
• Direct NMR-spectroscopic determination of active-enzyme concentration by titration with a labeled inhibitor: determination of the k(cat) value of almond beta-glucosidase.

  2000cited by this paper
• Sugar-mimic glycosidase inhibitors: natural occurrence, biological activity and prospects for therapeutic application

  2000cited by this paper
• Azafagomine hydrazones: an argument against a “Flat” transition state in glycoside cleavage

  2000cited by this paper
• Polycyclitols. Novel conduritol and carbasugar hybrids as a new class of potent glycosidase inhibitors

  2000cited by this paper
• Synthesis and evaluation of aminocyclopentitol inhibitors of beta-glucosidases.

  2000cited by this paper
• The effects of isofagomine, a potent glycogen phosphorylase inhibitor, on glycogen metabolism in cultured mouse cortical astrocytes.

  2000cited by this paper
• Glycosidase mechanisms.

  2000cited by this paper
• A general strategy towards the synthesis of 1-N-iminosugar type glycosidase inhibitors: demonstration by the synthesis of d- as well as l-glucose type iminosugars (isofagomines)

  2000cited by this paper
• Synthesis and Evaluation of Aminocyclopentitol Inhibitors of β-Glucosidases

  2000cited by this paper
• All eight stereoisomeric D-glyconic-delta-lactams: synthesis, conformational analysis, and evaluation as glycosidase inhibitors.

  2000cited by this paper
• Glycosidase inhibitors and their chemotherapeutic value, Part 3.

  2000cited by this paper
• Synthesis of the sialidase inhibitor siastatin B.

  2000cited by this paper
• Glycosidase inhibitors and their chemotherapeutic value, Part 1.

  2000cited by this paper
• Synthesis and Conformational Analysis of a Sulfonium-Ion Analogue of the Glycosidase Inhibitor Castanospermine

  2000cited by this paper
• Synthesis of C2-symmetric guanidino-sugars as potent inhibitors of glycosidases.

  2000cited by this paper
• Detailed structural analysis of glycosidase/inhibitor interactions: complexes of Cex from Cellulomonas fimi with xylobiose-derived aza-sugars.

  2000cited by this paper
• Sugar‐Derived Di‐ and Tetrahydropyridazinones: Synthesis of New Glycosidase Inhibitors

  2000cited by this paper
• Highly selective synthesis of 1-N-iminosugars of the D-glucose and -glucuronic acid types.

  2000cited by this paper
• Alkaloidal Sugar Mimetics: Biological Activities and Therapeutic Applications

  2000cited by this paper
• Investigation of the slow inhibition of almond beta-glucosidase and yeast isomaltase by 1-azasugar inhibitors: evidence for the 'direct binding' model.

  2000cited by this paper
• Synthesis of salacinol

  2000cited by this paper
• A norbornyl route to azasugars: stereoselective synthesis of isofagomine analogues

  2000cited by this paper
• Glycosidase mechanisms: anatomy of a finely tuned catalyst.

  1999cited by this paper
• Synthesis and biological evaluation of conduritol and conduramine analogs

  1999cited by this paper
• A Rationally Designed Inhibitor of α-1,3-Galactosyltransferase

  1999cited by this paper
• A facile synthesis of D-glucose-type gem-diamine 1-N-iminosugars: a new family of glucosidase inhibitors.

  1999cited by this paper
• Tetrazoles of manno- and rhamno-pyranoses: Contrasting inhibition of mannosidases by [4.3.0] but of rhamnosidase by [3.3.0] bicyclic tetrazoles

  1999cited by this paper
• THE FIRST COMBINATORIAL LIBRARY OF AZASUGAR GLYCOSIDASE INHIBITORS

  1999cited by this paper
• Anomer-selective inhibition of glycosidases using aminocyclopentanols.

  1999cited by this paper
• Homoisofagomines: Chemical-enzymatic synthesis and evaluation as α- and β-glucosidase inhibitors

  1999cited by this paper
• Selective inhibition of β-1,4- and α-1,3-galactosyltransferases: donor sugar-nucleotide based approach

  1999cited by this paper
• Synthesis of Glucose- and Mannose-Derived N-Acetylamino Imidazopyridines and their Evaluation as Inhibitors of Glycosidases

  1999cited by this paper
• A facile synthesis of D-galactose-type gem-diamine 1-N-iminosugar: a new family of galactosidase inhibitor.

  1999cited by this paper
• Recent Insights into Inhibition, Structure, and Mechanism of Configuration-Retaining Glycosidases.

  1999cited by this paper
• Chemoenzymatic Synthesis of Enantiopure 1-Azafagomine.

  1999cited by this paper
• Inhibition of cellobiohydrolases from Trichoderma reesei. Synthesis and evaluation of some glucose-, cellobiose-, and cellotriose-derived hydroximolactams and imidazoles.

  1999cited by this paper
• Lateral Protonation of a Glycosidase Inhibitor. Structure of the Bacillus agaradhaerens Cel5A in Complex with a Cellobiose-Derived Imidazole at 0.97 A Resolution

  1999cited by this paper
• Synthesis of an 1-azaglucose analogue with ring-oxygen retained

  1999cited by this paper
• Short synthesis of piperidine based hexopyranose minics. A remarkable example of syn hydrogenation

  1999cited by this paper
• Synthesis and Biological Activity of Natural Aminocyclopentitol Glycosidase Inhibitors: Mannostatins, Trehazolin, Allosamidins, and Their Analogues.

  1999cited by this paper
• Homoisofagomines: chemical-enzymatic synthesis and evaluation as alpha- and beta-glucosidase inhibitors.

  1999cited by this paper
• Synthesis of (+)-Azafagomine from D-xylose

  1999cited by this paper
• An Advantageous Synthesis of 5,6,7,8-Tetra-Hydrotetrazolo[1,5-a]Pyridines

  1999cited by this paper
• Enantioselective synthesis of a new family of α-l-fucosidase inhibitors

  1999cited by this paper
• Synthesis of C-(d-glycopyranosyl)ethylamines and C-(d-glycofuranosyl)methylamines as potential glycosidase inhibitors

  1999cited by this paper
• A Selectiveα-L-Fucosidase Inhibitor Based on an Aminocyclopentane Framework

  1999cited by this paper
• Imino sugars inhibit the formation and secretion of bovine viral diarrhea virus, a pestivirus model of hepatitis C virus: implications for the development of broad spectrum anti-hepatitis virus agents.

  1999cited by this paper
• Selective inhibition of beta-1,4- and alpha-1,3-galactosyltransferases: donor sugar-nucleotide based approach.

  1999cited by this paper
• The Synthesis of Imidazol Sugars Which Mimic Cyclic Carboxonium Ions Formed During the Glycosidase‐Catalysed Hydrolysis of Oligo and Polysaccharides

  1999cited by this paper
• Disarming flu viruses.

  1999cited by this paper
• Synthesis and deconvolution of the first combinatorial library of glycosidase inhibitors.

  1999cited by this paper
• Synthesis and glycosidase inhibitory activity of 5-thioglucopyranosylamines. Molecular modeling of complexes with glucoamylase.

  1999cited by this paper
• Efficient inhibition of muscle and liver glycogen phosphorylases by a new glucopyranosylidene-spiro-thiohydantoin.

  1999cited by this paper
• INHIBITION OF GLYCOSIDASES BY LACTAM OXIMES : INFLUENCE OF THE AGLYCON IN DISACCHARIDE ANALOGUES

  1998cited by this paper
• A glycosidase antibody elicited against a chair-like transition state analog by in vitro immunization.

  1998cited by this paper
• Snapshots along an enzymatic reaction coordinate: analysis of a retaining beta-glycoside hydrolase.

  1998cited by this paper
• Exploring the cellulose/xylan specificity of the beta-1,4-glycanase cex from Cellulomonas fimi through crystallography and mutation.

  1998cited by this paper
• Synthesis of a 2-deoxy-ribose type 1-N-iminosugar

  1998cited by this paper
• Kotalanol, a potent alpha-glucosidase inhibitor with thiosugar sulfonium sulfate structure, from antidiabetic ayurvedic medicine Salacia reticulata.

  1998cited by this paper

• Catalyzing Carbohydrate Cleavage: Glycosidases and Their Mechanisms.

  2026cites this paper
• A short synthesis of carbohydrate derived N-benzyl aminocyclopentitols through N-O bond cleavage of the corresponding isoxazolidine derivatives: Evaluation of their anticancer properties using in vitro and in silico studies.

  2025cites this paper
• Acid-catalysed rearrangement of acyl groups: synthesis of β-d-gluco aminocyclopentitols and carbanucleoside derivatives

  2025cites this paper
• In vitro comparison of the glycosidase inhibitory profile of isoiminosugars with their 1- and 5a-modified derivatives.

  2025cites this paper
• Non-carbohydrate syntheses of nucleoside analogues

  2025cites this paper
• Oxidative [3+2] annulation of activated pyridines for the synthesis of indolizinyl sulfonyl fluorides: a class of important pharmacophores.

  2025cites this paper
• Deoxygenated analogs of 2-deoxy-2,3-didehydro-N-acetyl neuraminic acid as inhibitors of human neuraminidase enzymes.

  2025cites this paper
• A 'chiron' approach to divergent synthesis of 2-C-tridecyl 1-N-iminosugar mimetics and their anticancer profile.

  2025cites this paper
• Lewis Acid-Mediated Domino Glycosylation/Cyclization of Substituted Glycals: A Stereoselective Route Toward the Synthesis of 1,2-Annulated C-Glycosides.

  2025cites this paper
• Exploring the Impact of Click Chemistry on Carbohydrate Derivatives and their Biological Properties

  2025cites this paper
• Enantiospecific Synthesis of Tetrahydroindolizines from Spiro-cyclopropanecarboxylated Sugars.

  2025cites this paper
• One-pot synthesis of novel iminosugar C-nucleosides based on the N-aryl iminium-ion.

  2025cites this paper
• Metal Catalyst-Free β-Amination of Branched rac-C8N-type such as C7N Carbasugars via Intramolecular aza-Michael Addition: Biological evolution, DFT studies and ADME Properties

  2024cites this paper
• Efficient synthesis for each of the eight stereoisomers of the iminosugars lentiginosine and 1,4-dideoxy-1,4-imino-D-arabinitol (DAB).

  2024cites this paper
• Crude extractchemical engineering: strategy for the library generation of novel bio-active chemical entities

  2024cites this paper
• Stereoselective synthesis of gem-dihalopiperidines via the halo-aza-Prins cyclization reaction: access to piperidin-4-ones and pyridines.

  2024cites this paper
• Acquiring stereospecific new pseudosugars: Obtaining rac-decahydro-1,4-epoxynaphthalene-2,3,5,6,7,8-hexaols from the Diels-Alder reaction and investigating their biological effects.

  2024cites this paper
• Binding interactions of hydrophobically-modified flavonols with β-glucosidase: fluorescence spectroscopy and molecular modelling study

  2023cites this paper
• Potent and Selective Cell-Active Iminosugar Inhibitors of Human α-N-Acetylgalactosaminidase (α-NAGAL).

  2023cites this paper
• Design and synthesis of iso-allo-DNJ and L-isoDALDP derivatives: pursuit of potent and selective inhibitors of α-glucosidase.

  2023cites this paper
• Synthesis, glycosidase inhibitory activity and computational studies of dideoxymethylnojirimycin and its derivatives

  2023cites this paper
• Exploration of the Transglycosylation Activity of Barley Limit Dextrinase for Production of Novel Glycoconjugates

  2023cites this paper
• Synthesis and evaluation of ent-Conduramine C-1 derivatives as α-glucosidase inhibitors via CSI-mediated amination reaction.

  2023cites this paper
• Diastereoselective Synthesis, Glycosidase Inhibition, and Docking Study of C-7-Fluorinated Casuarine and Australine Derivatives.

  2022cites this paper
• Three-Component Reaction of Sugar Hydroxylactone, Amine and Isocyanide for the Synthesis of Iminosugars

  2022cites this paper
• Synthetic access to syn-functionalised chiral hydroxy pyrrolidines and pyrrolidones: Evaluation of α-glucosidase inhibition activity, docking studies and pharmacokinetics prediction.

  2022cites this paper
• A hybrid of 1-deoxynojirimycin and benzotriazole induces preferential inhibition of butyrylcholinesterase (BuChE) over acetylcholinesterase (AChE)

  2022cites this paper
• Stereoselective synthesis of novel bis-homoinositols with bicyclo[4.2.0]octane motifs.

  2022cites this paper
• Fucoidan Regulates Starch Digestion: In Vitro and Mechanistic Study

  2022cites this paper
• Stereoselective Synthesis of Nojirimycin α-C-Glycosides from a Bicyclic Acyliminium Intermediate: A Convenient Entry to N,C-Biantennary Glycomimetics

  2022cites this paper
• QSER modeling of half-wave oxidation potential of indolizines by theoretical descriptors

  2022cites this paper
• Design, synthesis and glycosidase inhibition of C-4 branched LAB and DAB derivatives.

  2022cites this paper
• Investigation of the enantioselectivity of acetylcholinesterase and butyrylcholinesterase upon inhibition by tacrine-iminosugar heterodimers

  2022cites this paper
• Unusual seven-membered ring sugars and nucleosides: synthesis and biological properties

  2022cites this paper
• Combining Organocatalyzed Aldolization and Reductive Amination: An Efficient Reaction Sequence for the Synthesis of Iminosugars

  2021cites this paper
• Synthesis of hydroxymethyl analogues of mannostatin A and their evaluation as inhibitors of GH38 α-mannosidases

  2021cites this paper
• Ligand compatibility of salacinol-type α-glucosidase inhibitors toward the GH31 family

  2021cites this paper
• Application of carbohydrates in approved small molecule drugs: A review.

  2021cites this paper
• Stereoselective synthesis of a 4-⍺-glucoside of valienamine and its X-ray structure in complex with Streptomyces coelicolor GlgE1-V279S

  2021cites this paper
• Aromatic interactions in Glycochemistry: from molecular recognition to catalysis.

  2021cites this paper
• A Convenient Approach towards the Synthesis of ADMDP Type Iminosugars and Nojirimycin Derivatives from Sugar-Derived Lactams

  2021cites this paper
• Stereoselective Synthesis of a 4-⍺-Glucoside of Valienamine, Inhibition, and X-Ray Structural Studies Involving a Bacterial Glycoside Hydrolase-Like Enzyme of The GH13 Family

  2021cites this paper
• Synthesis and Evaluation of Novel Iminosugars Prepared from Natural Amino Acids

  2021cites this paper
• Functional design of glycan-conjugated molecules using a chemoenzymatic approach.

  2021cites this paper
• Review on the recent progress in the development of fluorescent probes targeting enzymes

  2021cites this paper
• Dysfunctional Inflammation in Cystic Fibrosis Airways: From Mechanisms to Novel Therapeutic Approaches

  2021cites this paper
• Shono‐Type Oxidation for Functionalization of N‐Heterocycles

  2021cites this paper
• Sugar-Derived Amidines and Congeners: Structures, Glycosidase Inhibition and Applications.

  2021cites this paper
• Structural analysis of halogenated bicyclo[4.2.0] inositols, biological activities and molecular docking studies

  2021cites this paper
• New total synthesis and structure confirmation of putative (+)-hyacinthacine C3 and (+)-5-epi-hyacinthacine C3

  2021cites this paper
• Inhibition of Clostridium difficile TcdA and TcdB toxins with transition state analogues

  2021cites this paper
• Enamides and dienamides in phosphoric acid-catalysed enantioselective cycloadditions for the synthesis of chiral amines.

  2021cites this paper
• Synthesis of Symmetrical Dodeco‐6,7‐diuloses

  2020cites this paper
• Synthesis of Isofagomine Derivatives as New Fluorescence pH Indicators/Glycosidase Inhibitors

  2020cites this paper
• O‐GlcNAcase: Emerging Mechanism, Substrate Recognition and Small‐Molecule Inhibitors

  2020cites this paper
• Total Syntheses of Kirkamide and N ‐acetyl ent ‐Conduramine B‐1

  2020cites this paper
• Carbohydrates: potential sweet tools against cancer.

  2020cites this paper
• Synthesis of Highly Oxygenated Bicyclic Carbasugars. Remarkable Difference in the Reactivity of the d-gluco and d-xylo- Derived Trienes

  2020cites this paper
• Synthesis and Therapeutic Applications of Iminosugars in Cystic Fibrosis

  2020cites this paper
• Stereoselective synthesis of (+)-5-thiosucrose and (+)-5-thioisosucrose

  2020cites this paper
• Contributing to the Study of Enzymatic and Chemical Glycosyl Transfer Through the Observation and Mimicry of Glycosyl Cations

  2020cites this paper
• Recent applications of the Wittig reaction in alkaloid synthesis.

  2020cites this paper
• Discovery of Novel Coumarin Analogs against the α-Glucosidase Protein Target of Diabetes Mellitus: Pharmacophore-Based QSAR, Docking, and Molecular Dynamics Simulation Studies

  2020cites this paper
• Chemoenzymatic Synthesis and Function of Chitin Derivatives.

  2020cites this paper
• A common strategy towards the synthesis of 1,4-dideoxy-1,4-imino-l-xylitol, deacetyl (+)-anisomycin and amino-substituted piperidine iminosugars.

  2020cites this paper
• Tuning the activity of iminosugars: novel N-alkylated deoxynojirimycin derivatives as strong BuChE inhibitors

  2020cites this paper
• Heparanase Inhibitors in Cancer Progression: Recent Advances.

  2020cites this paper
• Amino Acid-Based Synthesis and Glycosidase Inhibition of Cyclopropane-Containing Iminosugars

  2020cites this paper
• Iminosugars

  2020cites this paper
• 1,4-Dideoxy-1,4-imino-d-arabinitol (DAB) Analogues Possessing a Hydrazide Imide Moiety as Potent and Selective α-Mannosidase Inhibitors

  2020cites this paper
• Novel carbohydrate-triazole derivatives as potential α-glucosidase inhibitors.

  2020cites this paper
• Conformationally Restricted Oxazolidin‐2‐one Fused Bicyclic Iminosugars as Potential Glycosidase Inhibitors

  2020cites this paper
• Designed Heterocyclizing Reagents for Rapid Assembly of N-Fused Heteroarenes from Alkenes.

  2020cites this paper
• Stereodivergent routes in organic synthesis: carbohydrates, amino acids, alkaloids and terpenes.

  2020cites this paper
• Application 2D Descriptors and Artificial Neural Networks for Beta-Glucosidase Inhibitors Screening

  2020cites this paper
• Structural Dependence of Sulfated Polysaccharide for Diabetes Management: Fucoidan From Undaria pinnatifida Inhibiting α-Glucosidase More Strongly Than α-Amylase and Amyloglucosidase

  2020cites this paper
• A Convenient Synthetic Route towards 3,5‐Bis(hydroxymethyl)pyrrolizidines: Stereoselective Synthesis of Unnatural (–)‐Hyacinthacine B2

  2019cites this paper
• Synthesis of tricyclic quinazolinone-iminosugars as potential glycosidase inhibitors via a Mitsunobu reaction.

  2019cites this paper
• Design, synthesis and glycosidase inhibition studies of novel triazole fused iminocyclitol-δ-lactams.

  2019cites this paper
• Sn−Li Transmetalation of α‐Aminoorganostannanes for the Stereoselective Synthesis of Substituted Dehydropiperidines and Dehydroazepanes

  2019cites this paper
• Multivalent Effect in Glycosidase Inhibition: The End of the Beginning.

  2019cites this paper
• Spiro Iminosugars: Structural Diversity and Synthetic Strategies

  2019cites this paper
• Synthesis of conformationally constrained inhibitors for glycoside hydrolases

  2019cites this paper
• Chemical Diversification of Natural Product Extracts

  2019cites this paper
• Synthesis of 4a-Carba-d-lyxofuranose Derivatives and Their Evaluation as Inhibitors of GH38 α-Mannosidases

  2019cites this paper
• Probing of Carbohydrate-Protein Interactions Using Galactonoamidine Inhibitors

  2019influential citation
• Enantioselective synthesis of anti-3-alkenyl-2-amido-3-hydroxy esters: application to the total synthesis of (+)-alexine

  2019cites this paper
• A “turn off-on” fluorescent nanoprobe consisting of CuInS2 quantum dots for determination of the activity of β-glucosidase and for inhibitor screening

  2019cites this paper
• Stereoselective Synthesis of Highly Functionalized 5- and 6-Membered Aminocyclitols Starting with a Readily Available 2-Azetidinone.

  2019cites this paper
• Therapeutic significance of β-glucuronidase activity and its inhibitors: A review

  2019cites this paper
• The impact of aromatic stacking on glycoside reactivity: balancing CH/π and cation/π interactions for the stabilization of glycosyl-oxocarbenium ions.

  2019cites this paper
• N-Alkyl-1,5-dideoxy-1,5-imino-l-fucitols as fucosidase inhibitors: Synthesis, molecular modelling and activity against cancer cell lines.

  2019cites this paper
• Anodic Oxidation for the Stereoselective Synthesis of Heterocycles.

  2019cites this paper
• Capillary electrophoresis-based online immobilized enzyme reactor for beta-glucosidase kinetics assays and inhibitors screening.

  2019cites this paper
• Design, properties and applications of fluorinated and fluoroalkylated N-containing monosaccharides and their analogues

  2019cites this paper
• Synthesis of tricyclic benzimidazole-iminosugars as potential glycosidase inhibitors via a Mitsunobu reaction.

  2019cites this paper
• Synthesis and biological activity of diastereoisomeric octahydro-1H-indole-5,6,7-triols, analogues of castanospermine

  2019cites this paper
• Synthesis and glycosidase inhibition potency of all-trans substituted 1-C-perfluoroalkyl iminosugars.

  2018cites this paper
• Revealing the mechanism for covalent inhibition of glycoside hydrolases by carbasugars at an atomic level

  2018cites this paper
• Giant Glycosidase Inhibitors: First- and Second-Generation Fullerodendrimers with a Dense Iminosugar Shell.

  2018cites this paper