The relation of magnesium and calcium intakes and a genetic polymorphism in the magnesium transporter to colorectal neoplasia risk.

No abstract is available for this paper.

• Publication year

  2007

• Venue

  American Journal of Clinical Nutrition

• Publication date

  2007-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1093/AJCN/86.3.743PMID 17823441PMCID PMC2082111
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2007cited by this paper
• Magnesium and neoplasia: from carcinogenesis to tumor growth and progression or treatment.

  2007cited by this paper
• Magnesium intake and colorectal cancer risk in the Netherlands Cohort Study

  2007cited by this paper
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  2006cited by this paper
• Calcium plus vitamin D supplementation and the risk of colorectal cancer.

  2006cited by this paper
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  2006cited by this paper
• Type 2 diabetes as an inflammatory cardiovascular disorder.

  2005cited by this paper
• A TRPM7 variant shows altered sensitivity to magnesium that may contribute to the pathogenesis of two Guamanian neurodegenerative disorders.

  2005influential reference
• Essential role for TRPM6 in epithelial magnesium transport and body magnesium homeostasis

  2005influential reference
• Sources of variation in nutrient intakes among men in Shanghai, China

  2005cited by this paper
• Dietary calcium, phosphorus, vitamin D, dairy products and the risk of colorectal adenoma and cancer among French women of the E3N‐EPIC prospective study

  2005cited by this paper
• Magnesium intake in relation to risk of colorectal cancer in women

  2005cited by this paper
• Magnesium intake in relation to risk of colorectal cancer in women.

  2005cited by this paper
• Magnesium Intake and Risk of Coronary Heart Disease among Men

  2004cited by this paper
• Dairy foods, calcium, and colorectal cancer: a pooled analysis of 10 cohort studies.

  2004cited by this paper
• Disruption of TRPM6/TRPM7 complex formation by a mutation in the TRPM6 gene causes hypomagnesemia with secondary hypocalcemia.

  2004cited by this paper
• Dietary intake of selected minerals for the United States population: 1999-2000.

  2004cited by this paper
• Magnesium intake and risk of type 2 diabetes in men and women.

  2004cited by this paper
• Epithelial Ca2+ and Mg2+ channels in health and disease.

  2004influential reference
• Magnesium deficiency inhibits primary tumor growth but favors metastasis in mice.

  2004cited by this paper
• Variation in nutrient intakes among women in Shanghai, China

  2004cited by this paper
• Diet, Body Weight, and Colorectal Cancer: A Summary of the Epidemiologic Evidence

  2003cited by this paper
• Development of a culturally sensitive food frequency questionnaire for use in the Southern Community Cohort Study.

  2003cited by this paper
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  2003cited by this paper
• Risk factors for advanced colonic neoplasia and hyperplastic polyps in asymptomatic individuals.

  2003cited by this paper
• Regulation of Vertebrate Cellular Mg2 Homeostasis by TRPM7

  2003influential reference
• 'Mendelian randomization': can genetic epidemiology contribute to understanding environmental determinants of disease?

  2003cited by this paper
• Molecular mechanism of active Ca2+ reabsorption in the distal nephron.

  2002influential reference
• Protective effect of calcium deficiency on the inflammatory response in magnesium-deficient rats

  2002cited by this paper
• Sporadic colorectal cancers with microsatellite instability and their possible origin in hyperplastic polyps and serrated adenomas.

  2001cited by this paper
• Extracellular calcium sensing and extracellular calcium signaling.

  2001cited by this paper
• Population stratification in epidemiologic studies of common genetic variants and cancer: quantification of bias.

  2000influential reference
• Hyperplastic polyps and DNA microsatellite unstable cancers of the colorectum

  2000cited by this paper
• Calcium and fibre supplementation in prevention of colorectal adenoma recurrence: a randomised intervention trial. European Cancer Prevention Organisation Study Group.

  2000cited by this paper
• Calcium supplements for the prevention of colorectal adenomas. Calcium Polyp Prevention Study Group.

  1999cited by this paper
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  1998cited by this paper
• Cancer Incidence in Five Continents

  1997cited by this paper
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  1997cited by this paper
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  1996cited by this paper
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  1996cited by this paper
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  1996cited by this paper
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  1994cited by this paper
• Diet and risk of clinical diabetes in women.

  1992cited by this paper
• Magnesium absorption: mechanisms and the influence of vitamin D, calcium and phosphate.

  1991influential reference
• Correlates of fasting insulin levels in young adults: the CARDIA study.

  1991cited by this paper
• Mechanisms of magnesium transport.

  1991cited by this paper
• Effect of dietary magnesium supplementation in the prevention of coronary heart disease and sudden cardiac death.

  1990cited by this paper
• Magnesium: nature's physiologic calcium blocker.

  1984cited by this paper
• Colon cancer: its precursors and companions in Hawaii Japanese.

  1979cited by this paper
• Effect of salmon calcitonin on symptoms and urinary excretion of 5 hydroxyindoleacetic acid in the carcinoid syndrome.

  1978cited by this paper
• Cancer incidence in five continents.

  1976cited by this paper
• THE REQUIREMENT OF MAGNESIUM BY THE NORMAL ADULT. SUMMARY AND ANALYSIS OF PUBLISHED DATA.

  1964cited by this paper

• Reply to A. Guan.

  2025cites this paper
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  2025cites this paper
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  2025cites this paper
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  2025cites this paper
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  2025cites this paper
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  2025cites this paper
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  2025cites this paper
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  2025cites this paper
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  2024cites this paper
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  2024cites this paper
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  2024cites this paper
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  2024cites this paper
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  2024cites this paper
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  2023cites this paper
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  2023cites this paper
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  2023cites this paper
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  2023cites this paper
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  2023cites this paper
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  2023cites this paper
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  2022cites this paper
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  2022cites this paper
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  2022cites this paper
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  2022cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2017cites this paper
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  2016cites this paper