Domain organization of I kappa B alpha and sites of interaction with NF-kappa B p65

No abstract is available for this paper.

• Publication year

  1995

• Venue

  Molecular and Cellular Biology

• Publication date

  1995-04-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1128/MCB.15.4.2166PMID 7891711PMCID PMC230444
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Inducible nuclear expression of newly synthesized I kappa B alpha negatively regulates DNA-binding and transcriptional activities of NF-kappa B

  1995cited by this paper
• Inducible degradation of I kappa B alpha in vitro and in vivo requires the acidic C-terminal domain of the protein

  1995cited by this paper
• Autoregulation of I kappa B alpha activity.

  1994cited by this paper
• The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B.

  1994cited by this paper
• Role of cysteine62 in DNA recognition by the P50 subunit of NF-kappa B.

  1993cited by this paper
• Common structural constituents confer I kappa B activity to NF‐kappa B p105 and I kappa B/MAD‐3.

  1993cited by this paper
• Interaction of the C-terminal region of p105 with the nuclear localisation signal of p50 is required for inhinition of NF-ϰB binding activity

  1993cited by this paper
• Mutual regulation of the transcriptional activator NF-kappa B and its inhibitor, I kappa B-alpha.

  1993cited by this paper
• Control of nuclear factor-kappa B DNA-binding activity by inhibitory proteins containing ankyrin repeats.

  1993cited by this paper
• Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha: a mechanism for NF-kappa B activation

  1993cited by this paper
• The I kappa B proteins: members of a multifunctional family.

  1993cited by this paper
• In vivo control of NF‐kappa B activation by I kappa B alpha.

  1993cited by this paper
• Lipopolysaccharide induces phosphorylation of MAD3 and activation of c-Rel and related NF-kappa B proteins in human monocytic THP-1 cells.

  1993cited by this paper
• NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway.

  1993cited by this paper
• The IκB proteins: members of a multifunctional family

  1993influential reference
• GAL4-I kappa B alpha and GAL4-I kappa B gamma activate transcription by different mechanisms.

  1993cited by this paper
• Cytokine‐inducible expression in endothelial cells of an I kappa B alpha‐like gene is regulated by NF kappa B.

  1993cited by this paper
• Rapid proteolysis of I kappa B-alpha is necessary for activation of transcription factor NF-kappa B.

  1993cited by this paper
• Proteolytic degradation of MAD3 (I kappa B alpha) and enhanced processing of the NF-kappa B precursor p105 are obligatory steps in the activation of NF-kappa B.

  1993cited by this paper
• Promoter analysis of the gene encoding the I kappa B‐alpha/MAD3 inhibitor of NF‐kappa B: positive regulation by members of the rel/NF‐kappa B family.

  1993cited by this paper
• Regulation of the NF-kappa B/rel transcription factor and I kappa B inhibitor system.

  1993cited by this paper
• Regulation of the NF-?B/rel transcription factor and I?B inhibitor system

  1993cited by this paper
• GAL4-lϰBα and GAL4-lϰBγ activate transcription by different mechanisms

  1993cited by this paper
• Interaction of the C-terminal region of p105 with the nuclear localisation signal of p50 is required for inhibition of NF-kappa B DNA binding activity.

  1993influential reference
• Direct association of pp40/I kappa B beta with rel/NF-kappa B transcription factors: role of ankyrin repeats in the inhibition of DNA binding activity.

  1992cited by this paper
• I kappa B gamma, a 70 kd protein identical to the C-terminal half of p110 NF-kappa B: a new member of the I kappa B family.

  1992cited by this paper
• A novel mitogen-inducible gene product related to p50/p105-NF-kappa B participates in transactivation through a kappa B site

  1992cited by this paper
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  1992influential reference
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  1992influential reference
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  1992cited by this paper
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  1991influential reference
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  1991cited by this paper
• Cytoplasmic retention, DNA binding and processing of the NF‐kappa B p50 precursor are controlled by a small region in its C‐terminus.

  1991cited by this paper
• The p65 subunit is responsible for the strong transcription activating potential of NF‐kappa B.

  1991influential reference
• DNA binding and I kappa B inhibition of the cloned p65 subunit of NF-kappa B, a rel-related polypeptide.

  1991cited by this paper
• Cloning of an NF-kappa B subunit which stimulates HIV transcription in synergy with p65.

  1991cited by this paper
• Characterization of an immediate-early gene induced in adherent monocytes that encodes I kappa B-like activity.

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• Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF‐kappa B transcription factor and HIV‐1.

  1991influential reference
• Isolation of a rel-related human cDNA that potentially encodes the 65-kD subunit of NF-kappa B.

  1991influential reference
• Rel-associated pp40: an inhibitor of the rel family of transcription factors.

  1991influential reference
• DNA binding and IκB inhibition of the cloned p65 subunit of NF-κB, a rel-related polypeptide

  1991influential reference
• Cloning of the p50 DNA binding subunit of NF-κB: Homology to rel and dorsal

  1990influential reference
• Cloning of the p50 DNA binding subunit of NF-kappa B: homology to rel and dorsal.

  1990cited by this paper
• The DNA binding subunit of NF-κB is identical to factor KBF1 and homologous to the rel oncogene product

  1990cited by this paper
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  1990influential reference
• Sequence requirement for specific interaction of an enhancer binding protein (EBP1) with DNA.

  1989cited by this paper
• Enhancer binding protein (EBP1) makes base and backbone contacts over one complete turn of the DNA double helix.

  1989cited by this paper
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  1988cited by this paper
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  year unknowninfluential reference
• Control of nuclear factor-K B DNA-binding activity by inhibitory proteins containing ankyrin repeats

  year unknowninfluential reference
• Rapid Induction in Regenerating Liver of RL/IF-1 (an IKB That Inhibits NF-KB, RelB-p50, and c-Rel-p50) and PHF, a Novel KB Site-Binding Complex

  year unknowninfluential reference
• Mutual regulation of the transcriptional activator NF-cB and its inhibitor, I1cB-a

  year unknowncited by this paper
• GAL4-IxBa and GAL4-IxB-y activate transcription by different mechanisms

  year unknowninfluential reference
• A Novel Mitogen-Inducible Gene Product Related to p50/p105-NF-KB Participates in Transactivation through a KB Site

  year unknowncited by this paper
• Direct association of pp40/IKcBB with rel/NF-KcB transcription factors: Role of ankyrin repeats in the inhibition of DNA binding activity

  year unknowninfluential reference

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