Serologic marker candidates identified among B-cell linear epitopes of Nsp2 and structural proteins of a North American strain of porcine reproductive and respiratory syndrome virus.

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Virology

• Publication date

  2006-09-30

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/J.VIROL.2006.05.036PMID 16843516
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2001influential reference
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