Implication of brain cdc2 and MAP2 kinases in the phosphorylation of tau protein in Alzheimer's disease

No abstract is available for this paper.

• Publication year

  1992

• Venue

  FEBS Letters

• Publication date

  1992-08-17

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/0014-5793(92)81278-TPMID 1323485
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1992cited by this paper
• cdc2 kinase-induced destabilization of MAP2-coated microtubules in Xenopus egg extracts.

  1992cited by this paper
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• Hydrofluoric acid-treated tau PHF proteins display the same biochemical properties as normal tau.

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  1992cited by this paper
• Mitogen-activated-protein-kinase-catalyzed phosphorylation of microtubule-associated proteins, microtubule-associated protein 2 and microtubule-associated protein 4, induces an alteration in their function.

  1992cited by this paper
• Dynamics of gene expression for microtubule-associated protein MAP1B, embryonic alpha-tubulin and late neural beta-tubulin mRNAs in the hippocampus of aged rats.

  1992cited by this paper
• Extracellular signal-regulated kinases: ERKs in progress.

  1991cited by this paper
• Two novel kinases phosphorylate tau and the KSP site of heavy neurofilament subunits in high stoichiometric ratios

  1991cited by this paper
• A serine/threonine proline kinase activity is included in the tau protein kinase fraction forming a paired helical filament epitope.

  1991cited by this paper
• TPA‐induced activation of MAP kinase

  1991cited by this paper
• In vitro effects on microtubule dynamics of purified Xenopus M phase-activated MAP kinase

  1991cited by this paper
• Tau in Alzheimer's disease and Down's syndrome is insoluble and abnormally phosphorylated.

  1991cited by this paper
• Dissection of the protein kinase cascade by which nerve growth factor activates MAP kinases

  1991cited by this paper
• Stimulation of protein tyrosine phosphorylation by NMDA receptor activation

  1991cited by this paper
• Tau in Alzheimer neurofibrillary tangles. N- and C-terminal regions are differentially associated with paired helical filaments and the location of a putative abnormal phosphorylation site.

  1991cited by this paper
• Downregulation of CDC2 upon terminal differentiation of neurons.

  1991cited by this paper
• Platelet-activating factor- and thrombin-induced stimulation of p34cdc2-cyclin histone H1 kinase activity in platelets.

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• Patterns of aberrant sprouting in Alzheimer's disease.

  1991cited by this paper
• A68: a major subunit of paired helical filaments and derivatized forms of normal Tau.

  1991cited by this paper
• Specific association of an M-phase kinase with isolated mitotic spindles and identification of two of its substrates as MAP4 and MAP1B.

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  1991cited by this paper
• Evidence for the involvement of protein kinase C in neurodegenerative changes in cultured human cortical neurons.

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  1991cited by this paper
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  1989cited by this paper
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  1989cited by this paper
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  1989cited by this paper
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  1989cited by this paper
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  1988cited by this paper
• [Alzheimer's disease: study of the distribution of tau proteins constituting helical filament pairs in human central nervous tissue].

  1988cited by this paper
• Epitopes that span the tau molecule are shared with paired helical filaments.

  1988cited by this paper
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  1988cited by this paper
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  1988cited by this paper
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  1987cited by this paper
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  1987cited by this paper
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  1987cited by this paper
• Recognition of tau epitopes by anti-neurofilament antibodies that bind to Alzheimer neurofibrillary tangles.

  1987cited by this paper
• Recognition of Alzheimer paired helical filaments by monoclonal neurofilament antibodies is due to crossreaction with tau protein.

  1987cited by this paper
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  1986cited by this paper
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  1986cited by this paper
• Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology.

  1986cited by this paper
• Tau protein function in living cells

  1986cited by this paper
• The distribution of tau in the mammalian central nervous system

  1985cited by this paper
• MAP2 is localized to the dendrites of hippocampal neurons which develop in culture.

  1984cited by this paper
• Differences in the cellular distributions of two microtubule-associated proteins, MAP1 and MAP2, in rat brain

  1984cited by this paper
• Phosphorylation affects the ability of tau protein to promote microtubule assembly.

  1984cited by this paper
• Fractionation of Brain Microtubule‐Associated Proteins

  1978cited by this paper
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  1978cited by this paper
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