Species differences in the formation of butadiene monoxide from 1,3-butadiene

No abstract is available for this paper.

• Publication year

  1985

• Venue

  Archives of Toxicology

• Publication date

  1985-09-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1007/BF00324781PMID 3879165
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Biological activation of 1,3-butadiene to vinyl oxirane by rat liver microsomes and expiration of the reactive metabolite by exposed rats

  2004cited by this paper
• NTP Toxicology and Carcinogenesis Studies of 1,3-Butadiene (CAS No. 106-99-0) in B6C3F1 Mice (Inhalation Studies).

  1984cited by this paper
• Inhalation pharmacokinetics based on gas uptake studies

  1984cited by this paper
• Inhalation pharmacokinetics based on gas uptake studies

  1983cited by this paper
• Hepatic microsomal metabolism of 1,3-butadiene.

  1982cited by this paper
• Enzymatic hydration of butadiene monoxide and its importance in the metabolism of butadiene.

  1981cited by this paper
• Simplified liquid chromatographic assay for epoxide hydrolase.

  1980cited by this paper
• Microsomal Metabolism of Butadiene

  1980cited by this paper
• Influence of experimental factors on the mutagenicity of vinylic monomers.

  1980cited by this paper
• The mutagenicity of butadiene towards Salmonella typhimurium.

  1980cited by this paper
• Impact of microsomal enzymes on the mutagenicity of acrylonitrile, butadiene and styrene

  1979cited by this paper
• Identification and quantitation of 1,2-epoxybutene-3 as the primary metabolite of 1,3-butadiene

  1979cited by this paper
• Activities of polycyclic hydrocarbon activating and inactivating enzymes in human lungs of smokers, non-smokers, lung-cancer and non-cancer patients.

  1979cited by this paper
• A simple and sensitive assay of 7-ethoxycoumarin deethylation.

  1978cited by this paper
• An improved assay of 7-ethoxycoumarin O-deethylase activity: induction of hepatic enzyme activity in C57BL/6J and DBA/2J mice by phenobarbital, 3-methylcholanthrene and 2,3,7,8-tetrachlorodibenzo-p-dioxin.

  1978cited by this paper
• Mutagenicity of butadiene and butadiene monoxide.

  1978cited by this paper
• Mechanism of Microsomal Monooxygenases and Drug Toxicity

  1977cited by this paper
• The O-dealkylation of 7-ethoxycoumarin by liver microsomes. A direct fluorometric test.

  1972cited by this paper
• Determination of drug metabolizing enzymes in needle biopsies of human liver

  1972cited by this paper

• Use of biomarker data and metabolite relative potencies to support derivation of noncancer reference values based on the reproductive and developmental toxicity effects of 1,3-butadiene.

  2022cites this paper
• Use of Biomarker Data and Relative Potencies of Mutagenic Metabolites to Support Derivation of Cancer Unit Risk Values for 1,3-Butadiene from Rodent Tumor Data

  2022cites this paper
• Beyond Science and Decisions: From Problem Formulation to Dose-Response Assessment Case Study: Cancer Risk Assessment for 1,3-Butadiene Based on New Data and Methods

  2022cites this paper
• Genotoxicity evaluation of carbon monoxide and 1,3-butadiene using a new joint technology: the in vitro γH2AX HCS assay combined with air–liquid interface system

  2018cites this paper
• Tobacco Smoke–Related Health Effects Induced by 1,3-Butadiene and Strategies for Risk Reduction

  2013cites this paper
• Ermittlung der Belastung durch den Metaboliten 1,2:3,4-Diepoxybutan bei 1,3-Butadien-exponierten Ratten und Mäusen

  2012cites this paper
• Quantitative human health risk assessment for 1,3-butadiene based upon ovarian effects in rodents.

  2012cites this paper
• 1,3-Butadiene: I. Review of metabolism and the implications to human health risk assessment

  2010cites this paper
• In vitro biotransformation of 2-methylpropene (isobutene) in rat lung tissue in comparison with liver tissue

  2009cites this paper
• Toxicity and Carcinogenicity of Hydrocarbons

  2008cites this paper
• Assessment of the Potential Risk to Workers from Exposure to 1 , 3-Butadiene by

  2006cites this paper
• Evaluation of DNA damage by alkaline elution technique after inhalation exposure of rats and mice to 1,3-butadiene

  2005cites this paper
• In vitro biotransformation of 2-methylpropene (isobutene): Epoxide formation in mice liver

  2005cites this paper
• Enzyme specific kinetics of 1,2-epoxybutene-3 in microsomes and cytosol from livers of mouse, rat, and man

  2005cites this paper
• A physiologically based pharmacokinetic model for butadiene and its metabolite butadiene monoxide in rat and mouse and its significance for risk extrapolation

  2005cites this paper
• Inhalation pharmacokinetics of 1,2-epoxybutene-3 reveal species differences between rats and mice sensitive to butadiene-induced carcinogenesis

  2004cites this paper
• The use of non-tumor data in cancer risk assessment: reflections on butadiene, vinyl chloride, and benzene.

  2003cites this paper
• DOSE-DEPENDENT EXCRETION OF UNCONJUGATED 3-BUTENE-1,2-DIOL MEASURED IN URINE WITH A GC/MS AFTER 1,3-BUTADIENE EXPOSURE

  2002cites this paper
• A review of the genetic and related effects of 1,3-butadiene in rodents and humans.

  2000cites this paper
• Mutations of ras Protooncogenes and p53 Tumor Suppressor Gene in Cardiac Hemangiosarcomas from B6C3F1 Mice Exposed to 1,3-Butadiene for 2 Years

  2000cites this paper
• Comparison of cytogenetic effects of 3,4-epoxy-1-butene and 1,2:3, 4-diepoxybutane in mouse, rat and human lymphocytes following in vitro G0 exposures.

  1999cites this paper
• Identification of novel metabolites of butadiene monoepoxide in rats and mice.

  1998cites this paper
• Epoxybutene-hemoglobin adducts in rats and mice: dose response for formation and persistence during and following long-term low-level exposure to butadiene.

  1998cites this paper
• Oxidation of 1,3-butadiene to (R)- and (S)-butadiene monoxide by purified recombinant cytochrome P450 2E1 from rabbit, rat and human.

  1998cites this paper
• Threshold of “Genotoxic” carcinogens

  1998cites this paper
• Butadiene: species comparison for metabolism and genetic toxicology.

  1998cites this paper
• Disposition of butadiene epoxides in Sprague-Dawley rats following exposures to 8000 ppm 1,3-butadiene: comparisons with tissue epoxide concentrations following low-level exposures.

  1998cites this paper
• Toxicology and epidemiology of 1,3-butadiene.

  1997cites this paper
• Comparison of the disposition of butadiene epoxides in Sprague-Dawley rats and B6C3F1 mice following a single and repeated exposures to 1,3-butadiene via inhalation.

  1997cites this paper
• Stereochemical aspects of 1,3-butadiene metabolism and toxicity in rat and mouse liver microsomes and freshly isolated rat hepatocytes.

  1997cites this paper
• Oxidation of 3-butene-1,2-diol by alcohol dehydrogenase.

  1996cites this paper
• Biomonitoring of 1,3-butadiene and related compounds.

  1996cites this paper
• Metabolism of 1,3-butadiene: species differences.

  1996cites this paper
• Flow cytometric and histological assessment of 1,2:3,4-diepoxybutane toxicity on mouse spermatogenesis.

  1996cites this paper
• Mechanistic data indicate that 1,3-butadiene is a human carcinogen.

  1995cites this paper
• Analysis of butadiene, butadiene monoxide, and butadiene dioxide in blood by gas chromatography/gas chromatography/mass spectroscopy.

  1995cites this paper
• Gender differences in the metabolism of 1,3-butadiene in Sprague-Dawley rats following a low level inhalation exposure.

  1995cites this paper
• Molecular and genetic toxicology of 1,3-butadiene.

  1995cites this paper
• Species-dependent differences in biotransformation pathways of 2-methylpropene (isobutene).

  1995cites this paper
• Clastogenic effects of 1, 3‐butadiene and its metabolites 1,2‐epoxybutene and 1,2,3,4‐diepoxybutane in splenocytes and germ cells of rats and mice in vivo

  1995cites this paper
• Disposition of butadiene monoepoxide and butadiene diepoxide in various tissues of rats and mice following a low-level inhalation exposure to 1,3-butadiene.

  1995cites this paper
• Metabolism of 1,3-butadiene to butadiene monoxide in mouse and human bone marrow cells.

  1995cites this paper
• Comparison of blood concentrations of 1,3-butadiene and butadiene epoxides in mice and rats exposed to 1,3-butadiene by inhalation.

  1994cites this paper
• Species differences in urinary butadiene metabolites: comparisons of metabolite ratios between mice, rats, and humans.

  1994cites this paper
• Determining acceptable risks: experimental and epidemiological issues.

  1994cites this paper
• Environmental exposure to 1, 3‐butadiene: A human health perspective

  1994cites this paper
• A brief survey of butadiene health effects: a role for metabolic differences.

  1993cites this paper
• Treosulphan, myleran and butadiene: similarities and differences.

  1993cites this paper
• Physiologically based toxicokinetic modeling of 1,3-butadiene lung metabolism in mice becomes more important at low doses.

  1993cites this paper
• 1,3-Butadiene: toxicity and carcinogenicity in laboratory animals and in humans.

  1992cites this paper
• Species differences in urinary butadiene metabolites; identification of 1,2-dihydroxy-4-(N-acetylcysteinyl)butane, a novel metabolite of butadiene.

  1992cites this paper
• Species and tissue differences in the microsomal oxidation of 1,3-butadiene and the glutathione conjugation of butadiene monoxide in mice and rats. Possible role in 1,3-butadiene-induced toxicity.

  1992cites this paper
• Comparison of the biotransformation of 1,3-butadiene and its metabolite, butadiene monoepoxide, by hepatic and pulmonary tissues from humans, rats and mice.

  1992cites this paper
• Mechanisms of 1,3-butadiene oxidations to butadiene monoxide and crotonaldehyde by mouse liver microsomes and chloroperoxidase.

  1991cites this paper
• Use of biological markers and pharmacokinetics in human health risk assessment.

  1991cites this paper
• Activation of K-ras by codon 13 mutations in C57BL/6 X C3H F1 mouse tumors induced by exposure to 1,3-butadiene.

  1990cites this paper
• Assessment of the potential risk to workers from exposure to 1,3-butadiene.

  1990cites this paper
• In vitro and in vivo genotoxicity of 1,3-butadiene and metabolites.

  1990cites this paper
• Inhalation pharmacokinetics of 1,3-butadiene and 1,2-epoxybutene-3 in rats and mice.

  1990cites this paper
• Concentration-dependent depletion of non-protein sulfhydryl (NPSH) content in lung, heart and liver tissue of rats and mice after acute inhalation exposure to butadiene.

  1989cites this paper
• Metabolism of 1,3-butadiene by lung and liver microsomes of rats and mice repeatedly exposed by inhalation to 1,3-butadiene.

  1988cites this paper
• Depletion of hepatic non-protein sulfhydryl content during exposure of rats and mice to butadiene.

  1988cites this paper
• Genotoxic properties of 1,3-butadiene.

  1988cites this paper
• Alkylation of nuclear proteins and DNA after exposure of rats and mice to [1,4-14C]1,3-butadiene.

  1986cites this paper
• In vivo sister chromatid exchange and micronucleus induction studies with 1,3-butadiene in B6C3F1 mice and Sprague-Dawley rats.

  1986cites this paper
• Species differences in butadiene metabolism between mice and rats evaluated by inhalation pharmacokinetics

  1986cites this paper
• * Cited in Text + Cited in Supplemental Document ***draft for Public Comment***

  year unknowncites this paper