Role of phospholipase A(2) on the variations of the choline signal intensity observed by 1H magnetic resonance spectroscopy in brain diseases.

No abstract is available for this paper.

• Publication year

  2000

• Venue

  Brain research. Brain research reviews

• Publication date

  2000-09-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/S0165-0173(00)00037-0PMID 11011072
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Reduced concentrations of thalamic N-acetylaspartate in male patients with schizophrenia.

  2000cited by this paper
• Recovery of the brain choline level in treated Cushing's patients as monitored by proton magnetic resonance spectroscopy.

  2000cited by this paper
• A 1H MRS study of probable Alzheimer's disease and normal aging: implications for longitudinal monitoring of dementia progression.

  1999cited by this paper
• Characterization of choline compounds with in vitro 1H magnetic resonance spectroscopy for the discrimination of primary brain tumors.

  1999cited by this paper
• Magnetic Resonance Spectroscopy Diagnosis of Neurological Diseases

  1999cited by this paper
• Macrophage responses to Toxoplasma antigens in vitro: a possible role in inflammatory lesions in toxoplasmosis.

  1999cited by this paper
• Cerebral proton and phosphorus-31 magnetic resonance spectroscopy in patients with subclinical hepatic encephalopathy.

  1999cited by this paper
• Brain metabolic alterations in Cushing's syndrome as monitored by proton magnetic resonance spectroscopy

  1999cited by this paper
• [Proton magnetic resonance spectrometry for the non-invasive exploration of human brain metabolism: current and future clinical applications].

  1999cited by this paper
• Tumour phospholipid metabolism

  1999cited by this paper
• Neither short-term nor long-term administration of oral choline alters metabolite concentrations in human brain.

  1999cited by this paper
• Characterization of heparin low-affinity phospholipase A1 present in brain and testicular tissue.

  1999cited by this paper
• Aging of the adult human brain: In vivo quantitation of metabolite content with proton magnetic resonance spectroscopy

  1999cited by this paper
• A Proton Magnetic Resonance Spectroscopy Study of the Striatum and Cerebral Cortex in Parkinson's Disease

  1999cited by this paper
• In vivo spectroscopic quantification of the N‐acetyl moiety, creatine, and choline from large volumes of brain gray and white matter: Effects of normal aging

  1999cited by this paper
• Prognostic value of proton magnetic resonance spectroscopy in ischemic stroke.

  1998cited by this paper
• Quantitative proton magnetic resonance spectroscopy of the basal ganglia in patients with affective disorders

  1998cited by this paper
• Frontal lobe proton magnetic-resonance spectroscopy in Graves' disease: a pilot study.

  1998cited by this paper
• Decreased dorsolateral prefrontal N-acetyl aspartate in bipolar disorder.

  1998cited by this paper
• Serial precision of metabolite peak area ratios and water referenced metabolite peak areas in proton MR spectroscopy of the human brain.

  1998cited by this paper
• 31P magnetic resonance spectroscopy in the frontal lobe of major depressed patients

  1998cited by this paper
• 31Phosphorus magnetic resonance spectroscopy of the dorsolateral prefrontal region in schizophrenics--a study including 50 patients and 36 controls.

  1998cited by this paper
• Lack of effect of oral choline supplement on the concentrations of choline metabolites in human brain

  1998cited by this paper
• Phospholipid‐Metabolizing Enzymes in Alzheimer's Disease: Increased Lysophospholipid Acyltransferase Activity and Decreased Phospholipase A2 Activity

  1998cited by this paper
• Proton‐Decoupled 31P Magnetic Resonance Spectroscopy Reveals Osmotic and Metabolic Disturbances in Human Hepatic Encephalopathy

  1998cited by this paper
• Localised 1H-MR spectroscopy for metabolic characterisation of diffuse and focal brain lesions in patients infected with HIV

  1998cited by this paper
• Quantitative proton-decoupled 31P MRS and 1H MRS in the evaluation of Huntington's and Parkinson's diseases

  1998cited by this paper
• Clinical Applications of Magnetic Resonance Spectroscopy

  1997cited by this paper
• Involvement of phospholipase A2 in neurodegeneration.

  1997cited by this paper
• Cerebral cortical phospholipase A2 activity of senescence-accelerated mouse is increased in an age-dependent manner.

  1997cited by this paper
• The growing phospholipase A2 superfamily of signal transduction enzymes.

  1997cited by this paper
• Proton MR spectroscopic imaging of the striatum in Parkinson's disease.

  1997cited by this paper
• Increased choline signal coinciding with malignant degeneration of cerebral gliomas: a serial proton magnetic resonance spectroscopy imaging study.

  1997cited by this paper
• In vivo proton magnetic resonance spectroscopy of the normal aging human brain.

  1996cited by this paper
• Association study of bipolar disorder at the phospholipase A2 gene (PLA2A) in the Darier's disease (DAR) region of chromosome 12q23‐q24.1

  1996cited by this paper
• Susceptibility to TNF in the presence of inhibitors of transcription or translation is dependent on the activity of cytosolic phospholipase A2 in human melanoma tumor cells.

  1996cited by this paper
• Kinetics of choline transport and phosphorylation in human breast cancer cells; NMR application of the zero trans method.

  1996cited by this paper
• Regionally specific pattern of neurochemical pathology in schizophrenia as assessed by multislice proton magnetic resonance spectroscopic imaging.

  1996cited by this paper
• In vivo 1H MRS choline: correlation with in vitro chemistry/histology.

  1996cited by this paper
• Cytosolic phospholipase A2 (cPLA2) immunoreactivity is elevated in Alzheimer's disease brain.

  1996cited by this paper
• Reactive glia express cytosolic phospholipase A2 after transient global forebrain ischemia in the rat.

  1996cited by this paper
• Quantitative measurements with localized 1H MR spectroscopy in children with Canavan's disease

  1996cited by this paper
• Proton magnetic resonance spectroscopy: the new gold standard for diagnosis of clinical and subclinical hepatic encephalopathy?

  1996cited by this paper
• Choline ingestion increases the resonance of choline-containing compounds in human brain: an in vivo proton magnetic resonance study.

  1995cited by this paper
• Proton magnetic resonance spectroscopy of the left medial temporal and frontal lobes in chronic schizophrenia: preliminary report

  1995cited by this paper
• Radiologic-pathologic correlation. Cerebral toxoplasmosis and lymphoma in AIDS.

  1995cited by this paper
• Purification of a phosphatidic-acid-hydrolysing phospholipase A2 from rat brain.

  1995cited by this paper
• Abnormal frontal lobe phosphorous metabolism in bipolar disorder.

  1995cited by this paper
• Characterization of a Novel Phospholipase A2 Activity in Human Brain

  1995cited by this paper
• Decreased brain choline uptake in older adults. An in vivo proton magnetic resonance spectroscopy study.

  1995cited by this paper
• Transduction of physical force by the vascular wall Role of phospholipase C and cytochrome P450 metabolites of arachidonic acid.

  1995cited by this paper
• Brain lesions in patients with AIDS: H-1 MR spectroscopy.

  1995cited by this paper
• Proton magnetic resonance spectroscopy: an in vivo method of estimating hippocampal neuronal depletion in schizophrenia

  1995cited by this paper
• Alterations in the activity of phospholipases A2 in postmortem white matter from patients with multiple sclerosis

  1995cited by this paper
• Plasmalogens, phospholipases A2 and signal transduction.

  1995cited by this paper
• Clinical applications of magnetic resonance spectroscopy.

  1994cited by this paper
• Decrease in brain choline‐containing compounds following a short period of global ischemia in gerbils as detected by 1H NMR spectroscopy in vivo

  1994cited by this paper
• Diversity of group types, regulation, and function of phospholipase A2.

  1994cited by this paper
• Pressurization of isolated renal arteries increases inositol trisphosphate and diacylglycerol.

  1994cited by this paper
• Cerebral Phosphorus‐31 magnetic resonance spectroscopy in patients with chronic hepatic encephalopathy

  1994cited by this paper
• Activation of type D phospholipase by serum stimulation and ras-induced transformation in NIH3T3 cells.

  1994cited by this paper
• Proton magnetic resonance spectroscopy of basal ganglia in chronic schizophrenia

  1994cited by this paper
• In Vivo Proton Spectroscopy of Intracranial Infections and Neoplasms

  1994cited by this paper
• Brain choline in depression: in vivo detection of potential pharmacodynamic effects of antidepressant therapy using hydrogen localized spectroscopy.

  1994cited by this paper
• 1H magnetic resonance spectroscopy characterization of neuronal dysfunction in drug-naive, chronic schizophrenia.

  1994cited by this paper
• Proton spectroscopy of human brain: effects of age and sex.

  1994cited by this paper
• 1H-magnetic resonance spectroscopy of the left temporal and frontal lobes in schizophrenia: clinical, neurodevelopmental, and cognitive correlates.

  1994cited by this paper
• Abnormal cerebral metabolite concentrations in patients with probable alzheimer disease

  1994cited by this paper
• Regional variations in cerebral proton spectroscopy in patients with chronic hepatic encephalopathy

  1994cited by this paper
• Glucocorticoids inhibit soluble phospholipase C activity and cytosolic guanine nucleotide regulatory protein-alpha i immunoreactivity in spleen.

  1993cited by this paper
• Detection of neutral active phosphatidylcholine-specific phospholipase C in Friend leukemia cells before and after erythroid differentiation.

  1993cited by this paper
• Evidence for impairment of energy metabolism in vivo in Huntington's disease using localized 1H NMR spectroscopy.

  1993cited by this paper
• Evidence for irnnairment of energy metabofism in vivo in Huntington's disease using localized 1H NMR spectroscopy

  1993cited by this paper
• Secretory non-pancreatic group II phospholipase A2: role in physiologic and inflammatory processes.

  1993cited by this paper
• The proton NMR spectrum in acute EAE: The significance of the change in the Cho:Cr ratio

  1993cited by this paper
• Elevated PLA2 activity in schizophrenics and other psychiatric patients.

  1993cited by this paper
• Choline, a precursor of acetylcholine and phospholipids in the brain.

  1993cited by this paper
• Release of choline from rat brain under hypoxia: contribution from phospholipase A2 but not from phospholipase D.

  1993cited by this paper
• Plasma polyunsaturated fatty acids in liver cirrhosis with or without chronic hepatic encephalopathy: a preliminary study.

  1992cited by this paper
• Decreased phosphorus metabolite concentrations and alkalosis in chronic cerebral infarction.

  1992cited by this paper
• Identification and Purification of Calcium‐Independent Phospholipase A2 from Bovine Brain Cytosol

  1992cited by this paper
• Human brain infarction: proton MR spectroscopy.

  1992cited by this paper
• Proton NMR spectroscopy of Canavan's disease.

  1992cited by this paper
• Brain phosphorous metabolism in depressive disorders detected by phosphorus-31 magnetic resonance spectroscopy.

  1992cited by this paper
• Metabolic disorders of the brain in chronic hepatic encephalopathy detected with H-1 MR spectroscopy.

  1992cited by this paper
• 31P and 3‐fluoro‐3‐deoxy‐D‐glucose 19F In vivo NMR spectroscopy of aged rat brain

  1991cited by this paper
• Characterization of phospholipase A2 (PLA2) activity in gerbil brain: enhanced activities of cytosolic, mitochondrial, and microsomal forms after ischemia and reperfusion

  1991cited by this paper
• A review of chemical issues in 1H NMR spectroscopy: N‐acetyl‐l‐aspartate, creatine and choline

  1991cited by this paper
• Biochemical changes within a multiple sclerosis plaque in vivo.

  1991cited by this paper
• Proton magnetic resonance spectroscopy for metabolic characterization of plaques in multiple sclerosis

  1991cited by this paper
• Localized 1H NMR spectroscopy in patients with chronic hepatic encephalopathy. Analysis of changes in cerebral glutamine, choline and inositols

  1991cited by this paper
• Alterations in brain high-energy phosphate and membrane phospholipid metabolism in first-episode, drug-naive schizophrenics. A pilot study of the dorsal prefrontal cortex by in vivo phosphorus 31 nuclear magnetic resonance spectroscopy.

  1991cited by this paper
• Effects of hypernatremia on organic brain osmoles.

  1990cited by this paper
• Proton magnetic resonance spectroscopy in multiple sclerosis

  1990cited by this paper
• In vivo 13c nuclear magnetic resonance investigations of choline metabolism in rabbit brain

  1990cited by this paper
• Activation of phosphatidylcholine-specific phospholipase C in cell growth and oncogene transformation.

  1989cited by this paper
• Brain Phospholipase A2 Is Activated After Experimental Closed Head Injury in the Rat

  1989cited by this paper
• Combined 1H-MR imaging and localized 31P-spectroscopy of intracranial tumors in 43 patients.

  1988cited by this paper
• 31P Nuclear Magnetic Resonance Studies of Phosphoglyceride Metabolism in Developing and Degenerating Brain: Preliminary Observations

  1987cited by this paper
• Phosphatidylethanol Formation via Transphosphatidylation by Rat Brain Synaptosomal Phospholipase D

  1987cited by this paper

• Differences in biochemical metabolism and cognitive function between bipolar I and bipolar II disorder

  2026cites this paper
• Repeated Electroconvulsive Shock Transiently Affects Cognition and Neurometabolism in Mice.

  2025cites this paper
• Transdiagnostic reduction in cortical choline-containing compounds in anxiety disorders: a 1H-magnetic resonance spectroscopy meta-analysis

  2025influential citation
• Magnetic resonance spectroscopy in MELAS syndrome: correlation with CSF and plasma metabolite levels and change after glutamine supplementation

  2023cites this paper
• Neurometabolite levels in the brains of patients with autism spectrum disorders: A meta-analysis of proton magnetic resonance spectroscopy studies (N = 1501)

  2023cites this paper
• Restored retinal physiology after administration of niacin with citicoline in a mouse model of hypertensive glaucoma

  2023cites this paper
• Multi-Omics Analysis of Magnetically Levitated Plasma Biomolecules

  2022influential citation
• Kinetic isotope effects and synthetic strategies for deuterated carbon-11 and fluorine-18 labelled PET radiopharmaceuticals.

  2021cites this paper
• Alterations of Brain Metabolites in Adults With HIV

  2021cites this paper
• Effect of modified electroconvulsive therapy on neuro metabolites and magnetic resonance spectroscopy imaging signals in patients with refractory obsessive-compulsive disorder.

  2021cites this paper
• Proton magnetic resonance spectroscopic analysis of changes in brain metabolites following electroconvulsive therapy in patients with major depressive disorder

  2019influential citation
• Regional Metabolic Patterns of Abnormal Postoperative Behavioral Performance in Aged Mice Assessed by 1H-NMR Dynamic Mapping Method

  2019cites this paper
• Systematic review of in-vivo neuro magnetic resonance spectroscopy for the assessment of posttraumatic stress disorder.

  2018cites this paper
• WITHDRAWN: Correlative 1H MRS and High Resolution NMR Metabolomics to study Neurometabolic alterations in Rat Brain due to Chronic Hypobaric Hypoxia.

  2018cites this paper
• Functional neurochemical imaging of the human striatal cholinergic system during reversal learning

  2018cites this paper
• Region-specific aging of the human brain as evidenced by neurochemical profiles measured noninvasively in the posterior cingulate cortex and the occipital lobe using 1H magnetic resonance spectroscopy at 7 T.

  2017cites this paper
• Magnetic resonance spectroscopy abnormalities in traumatic brain injury: A meta-analysis.

  2017cites this paper
• In vivo functional neurochemistry of human cortical cholinergic function during visuospatial attention

  2017cites this paper
• Dietary phosphatidylcholine impacts on growth performance and lipid metabolism in adult Genetically Improved Farmed Tilapia (GIFT) strain of Nile tilapia Oreochromis niloticus.

  2017cites this paper
• Brain metabolite levels in recently sober individuals with alcohol use disorder: Relation to drinking variables and relapse.

  2016cites this paper
• Illness versus substance use effects on the frontal white matter in early phase schizophrenia: A 4Tesla (1)H-MRS study.

  2016cites this paper
• Concomitants of alcoholism: differential effects of thiamine deficiency, liver damage, and food deprivation on the rat brain in vivo

  2016cites this paper
• Correlation between neurochemical metabolism and memory function in adolescent patients with depression: A multi‐voxel 1H magnetic resonance spectroscopy study

  2016cites this paper
• Magnetic Resonance Spectroscopy in Major Depressive Disorder

  2015cites this paper
• Neurochemical changes in the pericalcarine cortex in congenital blindness attributable to bilateral anophthalmia.

  2015cites this paper
• Neurometabolic and structural alterations in rat brain due to acute hypobaric hypoxia: in vivo 1H MRS at 7 T

  2014cites this paper
• Investigating Cortical Changes in Cervical Spondylotic Myelopathy Using Functional Magnetic Resonance Imaging, Proton Magnetic Resonance Spectroscopy and Diffusion Tensor Imaging

  2014cites this paper
• Chronic alcohol consumption, abstinence and relapse: brain proton magnetic resonance spectroscopy studies in animals and humans.

  2013cites this paper
• Multimodal elucidation of choline metabolism in a murine glioma model using magnetic resonance spectroscopy and 11C-choline positron emission tomography.

  2013cites this paper
• Selective breeding for helplessness in rats alters the metabolic profile of the hippocampus and frontal cortex: a 1H-MRS study at 9.4 T.

  2013cites this paper
• A Guide to the Metabolic Pathways and Function of Metabolites Observed in Human Brain 1H Magnetic Resonance Spectra

  2013cites this paper
• Neurochemical changes within human early blind occipital cortex.

  2013cites this paper
• Rat strain differences in brain structure and neurochemistry in response to binge alcohol

  2013cites this paper
• Hippocampal abnormalities of glutamate/glutamine, N-acetylaspartate and choline in patients with depression are related to past illness burden.

  2013cites this paper
• Investigation of potential biomarkers of treatment-resistant schizophrenia

  2013cites this paper
• Development of NMR spectroscopic methods for dynamic detection of acetylcholine synthesis by choline acetyltransferase in hippocampal tissue

  2013cites this paper
• Detection of metabolites in the white matter of frontal lobes and hippocampus with proton in first‐episode treatment‐naïve schizophrenia patients

  2012cites this paper
• Brain Imaging in Behavioral Neuroscience

  2012cites this paper
• MR spectroscopy in opiate maintenance therapy: association of glutamate with the number of previous withdrawals in the anterior cingulate cortex

  2012cites this paper
• Metabolomics study of Buyang Huanwu Tang Decoction in ischemic stroke mice by 1H NMR

  2012cites this paper
• Is Brain Maturation Comparable in Fetuses and Premature Neonates at Term Equivalent Age?

  2011cites this paper
• Proton Magnetic Resonance Spectroscopy in adult cancer patients with delirium

  2011cites this paper
• Metabolic changes in visual cortex of neonatal monocular enucleated rat: a proton magnetic resonance spectroscopy study

  2011cites this paper
• Biochemical correlates of cognition: exploring the relationships between blood, brain and behaviour

  2011cites this paper
• Wirkung von Cannabinoiden auf das Gehirn: Ein Überblick über MRI Befunde

  2011cites this paper
• Apparent Diffusion Coefficients of Metabolites in Patients with MELAS Using Diffusion-Weighted MR Spectroscopy

  2011cites this paper
• MRI of experimental gliomas.

  2011cites this paper
• Magnetic Resonance Spectroscopy for Evaluation of Liposome-Encapsulated Hemoglobin as a Resuscitation Fluid

  2010cites this paper
• Specific metabolites in the medial prefrontal cortex are associated with the neurocognitive deficits in schizophrenia: A preliminary study

  2010cites this paper
• Effects of antidepressant treatment on N-acetyl aspartate and choline levels in the hippocampus and thalami of post-stroke depression patients: a study using (1)H magnetic resonance spectroscopy.

  2010cites this paper
• Neurochemical Alterations in Methamphetamine-Dependent Patients Treated with Cytidine-5′-Diphosphate Choline: A Longitudinal Proton Magnetic Resonance Spectroscopy Study

  2010cites this paper
• etabolic changes in visual cortex of neonatal monocular enucleated rat : a roton magnetic resonance spectroscopy study pril

  2010cites this paper
• A selective 15N-to-(1)H polarization transfer sequence for more sensitive detection of 15N-choline.

  2010cites this paper
• The Effect of Ethanol on Human Brain Metabolites Longitudinally Characterized by Proton MR Spectroscopy

  2009cites this paper
• Effects of overnight sleep restriction on brain chemistry and mood in women with unipolar depression and healthy controls.

  2009cites this paper
• Proton magnetic resonance spectroscopy revealed choline reduction in the visual cortex in an experimental model of chronic glaucoma.

  2009cites this paper
• Correlation between Choline Signal Intensity and Acetylcholine Level in Different Brain Regions of Rat

  2008influential citation
• Introduction to clinical in vivo MR spectroscopy.

  2008cites this paper
• Increased NAA and reduced choline levels in the anterior cingulum following chronic methylphenidate

  2008cites this paper
• Two distinct tumor phenotypes isolated from glioblastomas show different MRS characteristics

  2008cites this paper
• 31P magnetic resonance spectroscopy of endothelial cells grown in three-dimensional matrigel constructs as an enabling platform technology: II. The effect of anti-inflammatory drugs on phosphometabolite levels.

  2008cites this paper
• Cognitive MR spectroscopy of anterior cingulate cortex in ADHD: elevated choline signal correlates with slowed hit reaction times.

  2008cites this paper
• Reduced brain choline in homocystinuria due to remethylation defects

  2008cites this paper
• Effects of altered corticosteroid milieu on rat hippocampal neurochemistry and structure--an in vivo magnetic resonance spectroscopy and imaging study.

  2008cites this paper
• 1H MR spectroscopic imaging in patients with MRI-negative extratemporal epilepsy: correlation with ictal onset zone and histopathology

  2007cites this paper
• Dorsolateral prefrontal cortex N-acetylaspartate/total creatine (NAA/tCr) loss in male recreational cannabis users.

  2007cites this paper
• Proton magnetic resonance spectroscopy study of dyskinesia patients

  2007cites this paper
• Infratentorial pediatric brain tumors: the value of new imaging modalities.

  2007cites this paper
• Magnetic resonance imaging in relapsing-remitting multiple sclerosis

  2007cites this paper
• Multiparametric differentiation of posterior fossa tumors in children using diffusion‐weighted imaging and short echo‐time 1H‐MR spectroscopy

  2007cites this paper
• Magnetic Resonance Spectroscopy Detects Brain Injury and Predicts Cognitive Functioning in Children with Brain Injuries

  2006cites this paper
• Metabolic characterization of the R6/2 transgenic mouse model of Huntington's disease by high-resolution MAS 1H NMR spectroscopy.

  2006cites this paper
• The neurochemical basis of human cortical auditory processing: combining proton magnetic resonance spectroscopy and magnetoencephalography

  2006cites this paper
• Proton Magnetic Resonance Spectroscopy as a Monitoring Tool for Electroconvulsive Therapy Effects on the Brain

  2006cites this paper
• Correlation between MR-spectroscopic rat hippocampal choline levels and phospholipase A2

  2006influential citation
• The biochemistry of dysfunctional emotions: proton MR spectroscopic findings in major depressive disorder.

  2006cites this paper
• Alcohol consumption significantly influences the MR signal of frontal choline-containing compounds

  2006cites this paper
• The effect of antidepressant treatment on N-acetyl aspartate levels of medial frontal cortex in drug-free depressed patients.

  2006cites this paper
• A 1HMRS study of the anterior cingulate gyrus in euthymic bipolar patients

  2006cites this paper
• Effects of Mirtazapine on Hippocampal Metabolites of Female Patients with Major Depression

  2005cites this paper
• Monitoring the effects of chronic alcohol consumption and abstinence on brain metabolism: a longitudinal proton magnetic resonance spectroscopy study.

  2005cites this paper
• Glycerophosphocholine is elevated in cerebrospinal fluid of Alzheimer patients.

  2004cites this paper
• Choline rise in the rat hippocampus induced by electroconvulsive shock treatment.

  2003cites this paper
• Specific creatine rise in learned helplessness induced by electroconvulsive shock treatment

  2003cites this paper
• Increased choline levels coincide with enhanced proliferative activity of human neuroepithelial brain tumors

  2002cites this paper
• Brain metabolite changes in cortical grey and normal-appearing white matter in clinically early relapsing-remitting multiple sclerosis.

  2002cites this paper
• Electroconvulsive therapy in a patient receiving rivastigmine.

  2002cites this paper
• Long-term brain metabolic alterations in exogenous Cushing's syndrome as monitored by proton magnetic resonance spectroscopy.

  2001cites this paper