Differential Regulation of the Overlapping Kaposi's Sarcoma-Associated Herpesvirus vGCR (orf74) and LANA (orf73) Promoters

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Journal of Virology

• Publication date

  2001-02-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/JVI.75.4.1798-1807.2001PMID 11160678PMCID PMC114089
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Real-Time Quantitative PCR

  2002cited by this paper
• Molecular Cloning: A Laboratory Manual

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• Modulation of Cellular and Viral Gene Expression by the Latency-Associated Nuclear Antigen of Kaposi's Sarcoma-Associated Herpesvirus

  2001cited by this paper
• Epstein-Barr virus.

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• Kaposi's Sarcoma-Associated Herpesvirus Open Reading Frame 50/Rta Protein Activates the Entire Viral Lytic Cycle in the HH-B2 Primary Effusion Lymphoma Cell Line

  2000cited by this paper
• Inflammatory cytokines and the reactivation of Kaposi's sarcoma-associated herpesvirus lytic replication.

  2000influential reference
• Transgenic Expression of the Chemokine Receptor Encoded by Human Herpesvirus 8 Induces an Angioproliferative Disease Resembling Kaposi's Sarcoma

  2000cited by this paper
• Rta of Murine Gammaherpesvirus 68 Reactivates the Complete Lytic Cycle from Latency

  2000cited by this paper
• Experimental Transmission of Kaposi's Sarcoma–Associated Herpesvirus (Kshv/Hhv-8) to Scid-Hu Thy/Liv Mice

  1999influential reference
• Role of the Epstein-Barr Virus Rta Protein in Activation of Distinct Classes of Viral Lytic Cycle Genes

  1999cited by this paper
• p53 inhibition by the LANA protein of KSHV protects against cell death

  1999cited by this paper
• Comparison of Genetic Variability at Multiple Loci across the Genomes of the Major Subtypes of Kaposi’s Sarcoma-Associated Herpesvirus Reveals Evidence for Recombination and for Two Distinct Types of Open Reading Frame K15 Alleles at the Right-Hand End

  1999cited by this paper
• Identification of the Immediate-Early Transcripts of Kaposi’s Sarcoma-Associated Herpesvirus

  1999cited by this paper
• Long-Term Infection and Transformation of Dermal Microvascular Endothelial Cells by Human Herpesvirus 8

  1999cited by this paper
• Reactivation and persistence of human herpesvirus-8 infection in B cells and monocytes by Th-1 cytokines increased in Kaposi's sarcoma.

  1999cited by this paper
• The latency-associated nuclear antigen tethers the Kaposi's sarcoma-associated herpesvirus genome to host chromosomes in body cavity-based lymphoma cells.

  1999cited by this paper
• Characterization and Cell Cycle Regulation of the Major Kaposi’s Sarcoma-Associated Herpesvirus (Human Herpesvirus 8) Latent Genes and Their Promoter

  1999cited by this paper
• Kinetics of Kaposi’s Sarcoma-Associated Herpesvirus Gene Expression

  1999cited by this paper
• Transcriptional analysis of human herpesvirus-8 open reading frames 71, 72, 73, K14, and 74 in a primary effusion lymphoma cell line.

  1999cited by this paper
• A Complex Translational Program Generates Multiple Novel Proteins from the Latently Expressed Kaposin (K12) Locus of Kaposi’s Sarcoma-Associated Herpesvirus

  1999cited by this paper
• Induction of human herpesvirus-8 DNA replication and transcription by butyrate and TPA in BCBL-1 cells.

  1999cited by this paper
• Identification of Kaposin (Open Reading Frame K12) as a Human Herpesvirus 8 (Kaposi’s Sarcoma-Associated Herpesvirus) Transforming Gene

  1999cited by this paper
• Expression of the Open Reading Frame 74 (G-Protein-Coupled Receptor) Gene of Kaposi’s Sarcoma (KS)-Associated Herpesvirus: Implications for KS Pathogenesis

  1999influential reference
• Gene expression from the ORF50/K8 region of Kaposi's sarcoma-associated herpesvirus.

  1999cited by this paper
• Functional Analysis of Human Herpesvirus 8-Encoded Viral Interferon Regulatory Factor 1 and Its Association with Cellular Interferon Regulatory Factors and p300

  1999cited by this paper
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  1999cited by this paper
• KSHV strains: the origins and global spread of the virus.

  1999cited by this paper
• Transcriptional Activation by the Product of Open Reading Frame 50 of Kaposi’s Sarcoma-Associated Herpesvirus Is Required for Lytic Viral Reactivation in B Cells

  1999influential reference
• G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator

  1998cited by this paper
• Activation of Human Herpesvirus 8 (HHV-8) Thymidine Kinase (TK) TATAA-Less Promoter by HHV-8 ORF50 Gene Product Is SP1 Dependent

  1998cited by this paper
• Kaposi's sarcoma-associated herpesvirus (human herpesvirus-8).

  1998cited by this paper
• Reactivation of Kaposi's sarcoma-associated herpesvirus infection from latency by expression of the ORF 50 transactivator, a homolog of the EBV R protein.

  1998cited by this paper
• Kaposi’s Sarcoma-Associated Herpesvirus Viral Interferon Regulatory Factor

  1998cited by this paper
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  1998cited by this paper
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  1998influential reference
• A Cluster of Latently Expressed Genes in Kaposi’s Sarcoma-Associated Herpesvirus

  1998influential reference
• Persistent Infection of Epstein-Barr Virus-Positive B Lymphocytes by Human Herpesvirus 8

  1998cited by this paper
• The 222- to 234-kilodalton latent nuclear protein (LNA) of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) is encoded by orf73 and is a component of the latency-associated nuclear antigen

  1997cited by this paper
• The cyclin encoded by Kaposi's sarcoma-associated herpesvirus stimulates cdk6 to phosphorylate the retinoblastoma protein and histone H1

  1997cited by this paper
• Selective switch between latency and lytic replication of Kaposi's sarcoma herpesvirus and Epstein-Barr virus in dually infected body cavity lymphoma cells

  1997cited by this paper
• Expression of human herpesvirus 8-encoded cyclin D in Kaposi's sarcoma spindle cells.

  1997cited by this paper
• Kaposi's sarcoma-associated herpesvirus encodes a functional cyclin

  1997cited by this paper
• Cell-homologous genes in the Kaposi's sarcoma-associated rhadinovirus human herpesvirus 8: determinants of its pathogenicity?

  1997cited by this paper
• Human herpesvirus 8 encodes a homolog of interleukin-6

  1997cited by this paper
• Kaposi's sarcoma-associated herpesvirus gene expression in endothelial (spindle) tumor cells

  1997cited by this paper
• Propagation of a human herpesvirus from AIDS-associated Kaposi's sarcoma.

  1997cited by this paper
• The size and conformation of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) DNA in infected cells and virions

  1996cited by this paper
• Lytic growth of Kaposi's sarcoma–associated herpesvirus (human herpesvirus 8) in culture

  1996influential reference
• Real time quantitative PCR.

  1996cited by this paper
• Restricted expression of Kaposi sarcoma-associated herpesvirus (human herpesvirus 8) genes in Kaposi sarcoma.

  1996cited by this paper
• Human herpesvirus-8/Kaposi's sarcoma-associated herpesvirus is a new transmissible virus that infects B cells

  1996cited by this paper
• Nucleotide sequence of the Kaposi sarcoma-associated herpesvirus (HHV8).

  1996cited by this paper
• Transcription start sites downstream of the Epstein-Barr virus (EBV) Fp promoter in early-passage Burkitt lymphoma cells define a fourth promoter for expression of the EBV EBNA-1 protein

  1996cited by this paper
• Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomas.

  1995cited by this paper
• Kaposi's sarcoma-associated herpesvirus-like DNA sequences in multicentric Castleman's disease.

  1995cited by this paper
• Reversal of in vitro p53 squelching by both TFIIB and TFIID

  1995cited by this paper
• Redefining the Epstein-Barr virus-encoded nuclear antigen EBNA-1 gene promoter and transcription initiation site in group I Burkitt lymphoma cell lines.

  1995cited by this paper
• Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma.

  1994cited by this paper
• Specific repression of TATA-mediated but not initiator-mediated transcription by wild-type p53

  1993cited by this paper
• Wild-type p53 binds to the TATA-binding protein and represses transcription.

  1992cited by this paper
• p53 alteration is a common event in the spontaneous immortalization of primary BALB/c murine embryo fibroblasts.

  1991cited by this paper
• Regulation of transformation and the cell cycle by p53.

  1991cited by this paper
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  1990cited by this paper
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  1987cited by this paper
• QUANTITATIVE STUDIES OF THE GROWTH OF MOUSE EMBRYO CELLS IN CULTURE AND THEIR DEVELOPMENT INTO ESTABLISHED LINES

  1963cited by this paper

• Genotoxic consequences of viral infections

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• Kaposi’s sarcoma herpesvirus latency-associated nuclear antigen broadly regulates viral gene expression and is essential for lytic infection

  2024cites this paper
• Enhancer-promoter activation by the Kaposi sarcoma-associated herpesvirus episome maintenance protein LANA

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• RNA decay during gammaherpesvirus infection reduces RNA polymerase II occupancy of host promoters but spares viral promoters

  2020cites this paper
• Sp3 Transcription Factor Cooperates with the Kaposi’s Sarcoma-Associated Herpesvirus ORF50 Protein To Synergistically Activate Specific Viral and Cellular Gene Promoters

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• Reduction of Kaposi’s Sarcoma-Associated Herpesvirus Latency Using CRISPR-Cas9 To Edit the Latency-Associated Nuclear Antigen Gene

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• Xrn1 activity broadly represses RNA polymerase II occupancy at mammalian but not viral promoters during herpesvirus infection

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• Herpesvirus infection reduces Pol II occupancy of host promoters but spares viral promoters

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• Activation of DNA Damage Response Induced by the Kaposi’s Sarcoma-Associated Herpes Virus

  2016cites this paper
• Expression of the Antisense-to-Latency Transcript Long Noncoding RNA in Kaposi's Sarcoma-Associated Herpesvirus

  2016cites this paper
• Next-Generation Sequencing in the Understanding of Kaposi’s Sarcoma-Associated Herpesvirus (KSHV) Biology

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• Nuclear Innate Immune DNA Sensor IFI16 Is Degraded during Lytic Reactivation of Kaposi's Sarcoma-Associated Herpesvirus (KSHV): Role of IFI16 in Maintenance of KSHV Latency

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• Preparation and characterization of polyclonal antibody against Kaposi’s sarcoma-associated herpesvirus lytic gene encoding RTA

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• Murine Gammaherpesvirus 68 ORF48 Is an RTA-Responsive Gene Product and Functions in both Viral Lytic Replication and Latency during In Vivo Infection

  2015cites this paper
• Site-Specific Association with Host and Viral Chromatin by Kaposi's Sarcoma-Associated Herpesvirus LANA and Its Reversal during Lytic Reactivation

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• Kaposi’s Sarcoma-Associated Herpesvirus: Pathogenesis and Host Immune Response

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• LANA Binds to Multiple Active Viral and Cellular Promoters and Associates with the H3K4Methyltransferase hSET1 Complex

  2014cites this paper
• Keeping it quiet: chromatin control of gammaherpesvirus latency

  2013cites this paper
• Small and large-scale gene regulation in Kaposi's Sarcoma-associated Herpesvirus

  2013cites this paper
• Positive and negative regulation in the promoter of the ORF46 gene of Kaposi's sarcoma-associated herpesvirus.

  2012cites this paper
• CTCF Regulates Kaposi's Sarcoma-Associated Herpesvirus Latency Transcription by Nucleosome Displacement and RNA Polymerase Programming

  2012cites this paper
• Binding of Cellular Export Factor REF/Aly by Kaposi's Sarcoma-Associated Herpesvirus (KSHV) ORF57 Protein Is Not Required for Efficient KSHV Lytic Replication

  2012cites this paper
• The RBP-Jκ Binding Sites within the RTA Promoter Regulate KSHV Latent Infection and Cell Proliferation

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• Cohesins Repress Kaposi's Sarcoma-Associated Herpesvirus Immediate Early Gene Transcription during Latency

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• Quantitative Analysis of the Bidirectional Viral G-Protein-Coupled Receptor and Lytic Latency-Associated Nuclear Antigen Promoter of Kaposi's Sarcoma-Associated Herpesvirus

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• Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen Induction by Hypoxia and Hypoxia-Inducible Factors

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• Ribosomal Protein S 6 Interacts with the Latency-Associated Nuclear Antigen of Kaposi ’ s Sarcoma-Associated Herpesvirus

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• Activates the Expression of ORF18 Binds to an RTA-Responsive Element and (RTA) of Murine Gammaherpesvirus 68 Replication and Transcription Activator

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• Mechanism of Glycyrrhizic Acid Inhibition of Kaposi's Sarcoma-Associated Herpesvirus: Disruption of CTCF-Cohesin-Mediated RNA Polymerase II Pausing and Sister Chromatid Cohesion

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• Restricted Kaposi’s Sarcoma (KS) Herpesvirus Transcription in KS Lesions from Patients on Successful Antiretroviral Therapy

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• Ribosomal Protein S6 Interacts with the Latency-Associated Nuclear Antigen of Kaposi's Sarcoma-Associated Herpesvirus

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• Chromatin organization of gammaherpesvirus latent genomes.

  2010cites this paper
• Transcriptional regulation of the ORF61 and ORF60 genes of Kaposi's sarcoma-associated herpesvirus.

  2010cites this paper
• Induction of angiogenic chemokine CCL2 by human herpesvirus 8 chemokine receptor.

  2010cites this paper
• Molecular biology of Kaposi's sarcoma-associated herpesvirus and related oncogenesis.

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• Murine Gammaherpesvirus 68 LANA Is Essential for Virus Reactivation from Splenocytes but Not Long-Term Carriage of Viral Genome

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• Generation and Application of Polyclonal Antibody Against Replication and Transcription Activator of Kaposi’s Sarcoma-Associated Herpesvirus

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• Binding of RBP-Jkappa (CSL) protein to the promoter of the Kaposi's sarcoma-associated herpesvirus ORF47 (gL) gene is a critical but not sufficient determinant of transactivation by ORF50 protein.

  2010cites this paper
• Distinct p53, p53:LANA, and LANA Complexes in Kaposi's Sarcoma-Associated Herpesvirus Lymphomas

  2010cites this paper
• The replication and transcription activator (RTA) of Kaposi’s sarcoma-associated herpesvirus/human herpesvirus-8

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• Disruption of LANA in Rhesus Rhadinovirus Generates a Highly Lytic Recombinant Virus

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• Kaposi sarcoma-associated herpes virus (KSHV) G protein-coupled receptor (vGPCR) activates the ORF50 lytic switch promoter: a potential positive feedback loop for sustained ORF50 gene expression.

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• Regulation of Expression, Mode of Action and Downstream Targets of ORF50 Protein in KSHV Lytic Cycle Activation

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• KSHV Latent Genes and Their Regulation

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• Transcriptional regulation of the open reading frame 35 encoded by Kaposi's sarcoma-associated herpesvirus.

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