Communication: Resonance reaction in diffusion-influenced bimolecular reactions.

We investigate the influence of a stochastically fluctuating step-barrier potential on bimolecular reaction rates by exact analytical theory and stochastic simulations. We demonstrate that the system exhibits a new "resonant reaction" behavior with rate enhancement if an appropriately defined fluctuation decay length is of the order of the system size. Importantly, we find that in the proximity of resonance, the standard reciprocal additivity law for diffusion and surface reaction rates is violated due to the dynamical coupling of multiple kinetic processes. Together, these findings may have important repercussions on the correct interpretation of various kinetic reaction problems in complex systems, as, e.g., in biomolecular association or catalysis.

• Publication year

  2016

• Venue

  Journal of Chemical Physics

• Publication date

  2016-02-24

• Fields of study

  Medicine, Physics, Chemistry

• Identifiers
  DOI 10.1063/1.4942998arXiv 1602.07469PMID 26931674
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Communication: Resonance reaction in diffusion-influenced bimolecular reactions.

  2016cited by this paper
• Theory of Solvation-Controlled Reactions in Stimuli-Responsive Nanoreactors

  2015cited by this paper
• Both protein dynamics and ligand concentration can shift the binding mechanism between conformational selection and induced fit

  2014cited by this paper
• How hydrophobic drying forces impact the kinetics of molecular recognition

  2013cited by this paper
• Solvent fluctuations in hydrophobic cavity–ligand binding kinetics

  2013cited by this paper
• Charge regulation in biomolecular solution

  2013cited by this paper
• Weak temporal signals can synchronize and accelerate the transition dynamics of biopolymers under tension

  2012cited by this paper
• Thermosensitive Au-PNIPA yolk-shell nanoparticles with tunable selectivity for catalysis.

  2012cited by this paper
• Resonant activation in polymer translocation: new insights into the escape dynamics of molecules driven by an oscillating field

  2010cited by this paper
• Stochastic resonance vs. resonant activation

  2006cited by this paper
• Substrate concentration dependence of the diffusion-controlled steady-state rate constant.

  2004cited by this paper
• Experimental investigation of resonant activation

  2000cited by this paper
• Conformation gating as a mechanism for enzyme specificity.

  1998cited by this paper
• Surmounting fluctuating barriers: Basic concepts and results

  1997cited by this paper
• Thermally driven escape with fluctuating potentials: A new type of resonant activation.

  1995cited by this paper
• Stochastic Processes in Physics and Chemistry

  1995cited by this paper
• Thermally activated escape with potential fluctuations driven by an Ornstein-Uhlenbeck process.

  1995cited by this paper
• Rates of activated processes with fluctuating barriers.

  1994cited by this paper
• Thermally activated escape over fluctuating barriers.

  1993cited by this paper
• Resonant activation over a fluctuating barrier.

  1992cited by this paper
• Rate processes with dynamical disorder

  1990cited by this paper
• Protein fluctuations, distributed coupling, and the binding of ligands to heme proteins

  1988cited by this paper
• Diffusion-controlled macromolecular interactions.

  1985cited by this paper
• Fluctuation-dominated kinetics in diffusion-controlled reactions.

  1985cited by this paper
• Brownian dynamics simulation of diffusion‐influenced bimolecular reactions

  1984cited by this paper
• Transient kinetics of chemical reactions with bounded diffusion perpendicular to the reaction coordinate: Intramolecular processes with slow conformational changes

  1983cited by this paper
• Diffusion-Controlled Reactions

  1983cited by this paper
• Stochastically gated diffusion‐influenced reactions

  1982cited by this paper
• Stochastic Processes in Chemical Physics: The Master Equation

  1977cited by this paper
• Forces between Protein Molecules in Solution Arising from Fluctuations in Proton Charge and Configuration.

  1952cited by this paper
• Reaction Rates in Ionic Solutions

  1942cited by this paper

• Electrostatic Interactions Accelerating Water Oxidation Catalysis via Intercatalyst O-O Coupling.

  2021cites this paper
• Active binary switching of soft colloids: stability and structural properties.

  2021cites this paper
• The role of water in the kinetics of hydrophobic molecular recognition investigated by stochastic modeling and molecular simulations

  2018cites this paper
• Catalyzed Bimolecular Reactions in Responsive Nanoreactors

  2017cites this paper
• Communication: Resonance reaction in diffusion-influenced bimolecular reactions.

  2016cites this paper